Clinical trials: EMBRYO IMPLANTATION
Cataract
Visual Outcomes of Tecnis Symfony Opti-Blue EDOF Intraocular Lens (IOL)
Tecnis Symfony Optiblue EDOF IOL is the latest version of Tecnis Symfony IOL with a violet light filter (VLF), which blocks short-wavelength light and improves the quality of vision while minimizing visual disturbances.
- Trial name
- NCT06500416
- Testing
- Tecnis Symfony OptiBlue/ Tecnis Symfony OptiBlue toric IOL
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Coastal Eye Surgeons PLLC
Cataract
Visual Function After Implantation of Bilateral AcrySof® Toric Natural Intraocular Lens
The purpose of this study is to evaluate the effect that placement and power of the AcrySof Toric has on post-operative visual acuity and spectacle independence for distance vision.
- Trial name
- NCT00760487
- Testing
- AcrySof Toric IOL
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Alcon Research
Coronary Artery Disease, Atrial Fibrillation
Rivaroxaban Estimation With Warfarin in Atrial Fibrillation Patients With Coronary Stent Implantation Study (REWRAPS)
Antiplatelet therapy is indispensable for the prevention of stent thrombosis in patients who underwent coronary artery stenting.
- Conditions
- Coronary Artery Disease, Atrial Fibrillation, Stroke, Fetal Blood Loss
- Trial name
- REWRAPS (NCT02024230)
- Testing
- Rivaroxaban or Warfarin
- Where
- Japan
- Volunteers
- 500 people
- Sponsor
- Fujita Health University
Corneal Edema
EndoArt® Implantation in Subjects With Chronic Corneal Edema
The EndoArt® is intended to be used as an endothelial prosthesis in patients with chronic corneal edema.The EndoArt® (Artificial Endothelial layer) is a permanent implant, constructed of a clear, transparent, foldable…
- Trial name
- NCT05139771
- Testing
- THE ENDOART® IMPLANTATION (Artificial Endothelial layer)
- Where
- 12 sites in France, Georgia and 4 more
- Volunteers
- 52 people
- Sponsor
- Eye-yon Medical
Infertility, Subfertility
The Accuracy of Endometrial Ultrasound to Predict Implantation
To measure the accuracy of different ultrasound endometrial patterns to predict successful embryo implantation during assisted conception; in vitro fertilisation (IVF) or intracytoplasmic sperm injection (ICSI).
- Trial name
- NCT03860636
- Testing
- Endometrial Pattern on Ultrasound at ET, Endometrial Pattern on Ultrasound at HCG, Endometrial Pattern on Ultrasound at TVOR
- Where
- United Kingdom
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Endometrial Injury, Hysteroscopy
The Combination of Endometrial Injury and Freeze All Strategy in Women With a History of RIF
The investigators checked the hypothesis whether endometrial injury performed during the cycle before a frozen embryo transfer in women with RIF can improve pregnancy rates
- Conditions
- Endometrial Injury, Hysteroscopy, Repeated Implantation Failures
- Trial name
- NCT04597463
- Testing
- Endometrial injury
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Coronary Artery Disease
Ischemic and Bleeding Outcomes After Angiolite Stent Implantation and an Abbreviated Dual Antiplatelet Therapy
Factorial 2x2, all-comer, multicentre, randomized controlled trial (ratio 1:1:1:1). First, the study will compare (first randomization) the non-inferiority in target lesion failure of angiolite stent versus Xience stent family.
- Trial name
- ANGIODAPT (NCT05952206)
- Testing
- Angiolite: Sirolimus-eluting stent, Xience: Everolimus-eluting stent, 1-month DAPT
- Where
- 38 sites in Belgium, France and 1 more
- Volunteers
- 2,312 people
- Sponsor
- iVascular S.L.U.
Ischemic Congestive Heart Failure
Safety and Efficacy of Adipose Derived Stem Cells for Congestive Heart Failure
The intent of this clinical study is to answer the questions: 1. Is the proposed treatment safe 2. Is treatment effective in improving the disease pathology of patients with Heart Disease as assessed by a series of measurements…
- Trial name
- NCT01502514
- Testing
- Fat Harvesting and Implantation of Adipose Derived Stem Cells
- Where
- Mexico
- Sponsor
- Ageless Regenerative Institute
Visual Acuity
Clinical Assessment of Visual Function With the Acrysof ReSTOR Multifocal IOL
The purpose of this study is to assess uniocular and binocular unaided distance, intermediate, and near VA; contrast sensitivity, accommodation amplitude, stereopsis, glare testing, ocular aberrations and the clinical…
- Trial name
- NCT00759096
- Testing
- RESTOR IOL Model SA60D3
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Alcon Research
Aortic Stenosis
TRanscatheter Aortic-Valve Implantation Without On-site Cardiac Surgery
TRACS-PRIME is a prospective, randomized, multicenter clinical trial evaluating whether transcatheter aortic valve implantation (TAVI) can be performed safely and effectively in selected hospitals without on-site cardiac surgery…
- Trial name
- TRACS-PRIME (NCT07604402)
- Testing
- Transcatheter Aortic Valve Implantation
- Where
- 11 sites in Italy
- Volunteers
- 1,612 people
- Sponsor
- University Hospital of Ferrara
Infertility
OBE001 Phase 2 Dose-finding Study Versus Placebo in Women Undergoing Embryo Transfer in the Context of IVF-ICSI
The primary objective of this study is to assess the increase in clinical pregnancy rate after administration of a range of single oral doses of OBE001, an oral oxytocin antagonist, compared to placebo.
- Trial name
- IMPLANT (NCT02310802)
- Testing
- OBE001 dose 1, OBE001 dose 2, OBE001 dose 3
- Where
- 18 sites in Belgium, Czechia and 4 more
- Volunteers
- 247 people
- Sponsor
- ObsEva SA
Patients Who Are Scheduled to Undergo a PCI (Percutaneous Coronary Intervention) for CTO (Chronic Total Occlusion)
TIcaGrEloR and ABSORB Bioresorbable Vascular Scaffold Implantation for Recovery of Vascular Function After Successful Chronic Total Occlusion Recanalization
The study is a single-centre, randomized, active controlled, open label clinical trial. The primary hypothesis is that ticagrelor will show superiority over clopidogrel immediately after CTO-PCI (chronic total occlusion …
- Trial name
- TIGER-BVS (NCT02211066)
- Testing
- Clopidogrel, Ticagrelor
- Where
- 2 sites in Spain
- Volunteers
- 59 people
- Sponsor
- Hospital Clinic of Barcelona
Microtia
Long-Term Follow-Up Study of Unilateral Microtia Patients Implanted With AUR-201
Long-term follow-up of unilateral microtia patients implanted with AUR-201.
- Trial name
- AUR-201 (NCT06078566)
- Testing
- AUR-201
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Auregen Biotherapeutics, SA
Pulmonary Regurgitation
Implantation of the Venus P-Valve™ in the Pulmonic Position in Patients With Native Outflow Tracts
A prospective, non-randomized multi-center clinical investigation of the Venus P-Valve™ for the treatment of pulmonary regurgitation with or without stenosis in patient with native outflow tracts.
- Trial name
- NCT02846753
- Testing
- trans catheter heart valve replacement
- Volunteers
- 84 people
- Sponsor
- Venus MedTech (HangZhou) Inc.
Infertility
Using Embryo Organoids to Discover Human-specific Mechanisms of Preimplantation Embryo Development and Early Pregnancy
EMBRYOx study aims to establish and validate the use of trophoblast organoids (embryoids) from trophoblast placental stem cells as a 3D research model in understanding further preimplantation embryo development in vitro.
- Trial name
- EMBRYOx (NCT05231551)
- Testing
- Placental tissues
- Where
- France
- Volunteers
- 5 people
- Sponsor
- University Hospital, Montpellier
Aortic Stenosis, Multi Vessel Coronary Artery Disease
The TransCatheter Valve and Vessels Trial
The trial objective is to investigate whether Fractional Flow Reserve (FFR)-Guided Percutaneous Coronary Intervention (PCI) and TransCatheter Aortic Valve Implantation (TAVI) strategy for treatment of multivessel disease and…
- Conditions
- Aortic Stenosis, Multi Vessel Coronary Artery Disease, TAVI, CABG
- Trial name
- TCW (NCT03424941)
- Testing
- FFR-guided PCI and TAVI, CABG and SAVR
- Where
- 20 sites in Austria, Denmark and 8 more
- Volunteers
- 172 people
- Sponsor
- Maatschap Cardiologie Zwolle
Aortic Valve Stenosis
Engager Align Post-market Clinical Study
Purpose To characterize the safety and clinical benefit of the Engager Transcatheter Aortic Valve Implantation System in a real world environment.
- Trial name
- NCT02149654
- Testing
- Engager Transcatheter Aortic Valve Implantation System
- Where
- Netherlands
- Volunteers
- 27 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Effect on Implantation and Pregnancy Rates
Effect of Seminal Plasma Insemination on Pregnancy Rates After IVF-ET
Seminal plasma insemination into the vaginal vault of patients undergoing IVF-ET increases uterine receptivity.
- Trial name
- NCT01809366
- Testing
- seminal plasma insemination
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Assaf-Harofeh Medical Center
Infertility
Incidence of Non Receptive Endometrium in Obese Women
This study evaluates the incidence of Non Receptive endometrium in obese infertile women compared to infertile normal weight women using Endometrial Receptivity Array (ERA) test, containing 238 genes, identifying the receptivity…
- Trial name
- NCT02205866
- Testing
- Endometrial Receptivity Array analysis of endometrial biopsy
- Where
- 3 sites in United States, Spain
- Volunteers
- 183 people
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Infertility, Infertility (IVF Patients)
Endometrial Receptivity Prediction During in Vitro Fertilization Using Artificial Intelligence
The investigators plan to use artificial intelligence to analyse vaginal ultrasound images of the uterine lining (endometrium) taken during routine IVF treatment, which may predict implantation success during IVF treatment.
- Trial name
- NCT06717802
- Where
- Hungary
- Volunteers
- 1,500 people
- Sponsor
- Gottsegen National Cardiovascular Institute
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