Clinical trials: EMBRYO IMPLANTATION
Hearing Loss, Unilateral, Deafness, Unilateral
Investigation to Evaluate the Safety and Effectiveness of Cochlear Implantation in Children and Adults With Unilateral Hearing Loss/Single-sided Deafness
The aim of the study is to assess the continued efficacy and safety of cochlear implantation in participants aged 5 years and above with Unilateral Hearing Loss (UHL)/Single Sided Deafness (SSD) supporting a change indication for…
- Trial name
- PAS-SSD (NCT05318417)
- Testing
- The Cochlear™ Nucleus® Cochlear Implant (CI) System
- Where
- 6 sites in United States
- Volunteers
- 60 people
- Sponsor
- Cochlear
Aortic Stenosis
TAVI Without On-Site Cardiac Surgery in Poland: A Randomized Multicenter Trial Protocol
Aortic stenosis (AS) represents the most prevalent acquired valvular heart disease in European populations, and transcatheter aortic valve implantation (TAVI) has become the dominant treatment modality for patients with…
- Trial name
- NOSCAR-TAVI (NCT07515768)
- Testing
- transcathter aortic valve implantation
- Volunteers
- 404 people
- Sponsor
- Medical University of Warsaw
Aortic Stenosis, Cardiogenic Shock
Transcatheter AortiC Valve Implantation in aorTic stenosIs CardiogenIc Shock
The goal of this clinical trial is to learn if acute transcatheter aortic valve implantation (TAVI) is superior to standard treatment (stabilization in an intensive care unit and TAVI subsequently) to treat cardiogenic shock in…
- Trial name
- TACTICS (NCT06638268)
- Testing
- Acute TAVI, Stabilization and subacute TAVI
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Cardiac Arrest, Heart Arrest
ICD Shock Detection by a Wearable
Trial to assess the ability of a wearable to detect defibrillation from an implantable ICD
- Conditions
- Cardiac Arrest, Heart Arrest, Cardiopulmonary Arrest
- Trial name
- LOISICD (NCT04565652)
- Testing
- Device Wearers
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Lois Medical LTD
Lenses, Intraocular, Glaucoma Filtration Implants
Visual Function and Patient Satisfaction in Glaucoma or Ocular Hypertensive Patients Undergoing Simultaneous Cataract Surgery and i-Stent Implantation
New extended depth of focus intraocular lenses (IOLs) are being used in a broader spectrum of patients than trifocal IOLs. The purpose of this study is to evaluate visual improvement after cataract surgery in patients with…
- Trial name
- NCT05392738
- Testing
- I-Stent implantation
- Where
- Spain
- Volunteers
- 45 people
- Sponsor
- Clínica Rementería
Cataract
Postoperative Discomfort and Ocular Redness Following Phacoemulsification Surgery
Primary objective of the study is the assessment of the patients' discomfort and ocular redness following cataract extraction surgery by means of phacoemulsification and intraocular lens implantation.
- Trial name
- NCT02558218
- Testing
- Systane Ultra, tobradex quid (Standard)
- Where
- Greece
- Volunteers
- 80 people
- Sponsor
- Democritus University of Thrace
Cardiac Implantable Electronic Device Implantation
Educational Intervention for Elderly Patients With Cardiac Implantable Electronic Devices and Their Family Caregivers
This study evaluated whether a Family-Centered Empowerment Model could improve health status and functional independence and reduce complications in older adults after cardiac implantable electronic device (CIED) implantation.
- Trial name
- NCT07857915
- Testing
- Family-Centered Empowerment Model (FCEM), Routine Care
- Where
- Iran
- Volunteers
- 80 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Osteoarthritis
Safety and Efficacy of Autologous Bone Marrow Stem Cells for Treating Osteoarthritis
Osteoarthritis is a leading cause of chronic disability in elderly and the risk of disability attributed to osteoarthritis is as great as or greater than due to any other medical condition in that age group.
- Trial name
- NCT01152125
- Testing
- Autologous bone marrow stem cells
- Where
- India
- Volunteers
- 10 people
- Sponsor
- International Stemcell Services Limited
Subfertility
BAP-EB as a Predictive Tool for Endometrial Receptivity and Pregnancy Outcome of IVF Treatment
To determine the predictive value of attachment rate of human embryonic stem cells (hESC)-derived trophoblast spheroids (BAP-EB, embryo surrogate) onto endometrial epithelial cells (EEC) on success of IVF treatment and to use the…
- Trial name
- NCT02713854
- Testing
- endometrial biopsy
- Where
- China
- Volunteers
- 240 people
- Sponsor
- The University of Hong Kong
Pacemaker, ICD
Monaldi Hospital Rhythm Registry
The study is a prospective registry. Consecutive patients with indications of implant / replacement or upgrade of pacemaker (PM), implantable cardioverter defibrillator (ICD), Implanted loop recorder (ILR) will be enrolled.
- Conditions
- Pacemaker, ICD, Implanted Loop Recorder
- Trial name
- NCT05072119
- Testing
- Device implantation
- Where
- Italy
- Volunteers
- 5,000 people
- Sponsor
- University of Campania Luigi Vanvitelli
Glaucoma
AGV Implantation With Ologen in Pediatric Glaucomas
Ahmed Glaucoma Valve Implantation with Ologen augmentation in secondary pediatric glaucomas: A 2-year randomized controlled trial. Background: Many studies have investigated the clinical benefits of Ologen for trabeculectomy.
- Trial name
- NCT05014386
- Testing
- Ahmed Glaucoma Valve Implantation in secondary pediatric glaucomas., Ahmed Glaucoma Valve Implantation with Ologen augmentation in secondary pediatric glaucomas
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Deafness
Neurophysiological Measures of Auditory Perception and Rehabilitation in Cochlear Implanted Patients
This study aims at investigating new automatic fitting techniques for cochlear implant patients based on objective measures. For this reason, the evolution of these neurophysiological measures, expressing the encoding of pure…
- Trial name
- NEUROSYLLABIC (NCT02323256)
- Testing
- Auditory steady-state response ASSR, Speech-ABR, Acoustic Change Complex ACC
- Where
- France
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Ataxia - Other, Dystonia Disorder
Stimulation of the Dentate Nucleus of the Cerebellum for the Treatment of Refractory Spasticity With or Without Dystonia
Electrical stimulation (DBS) through electrodes implanted in the dentate nucleus of the cerebellum for the treatment of tremor intractable with medication, dystonia due to cerebrovascular disease (stroke), sequelae of traumatic…
- Conditions
- Ataxia - Other, Dystonia Disorder, Tremor, Essential, Choreatic Disorder
- Trial name
- DN_DBS (NCT07231302)
- Testing
- Analytical observation
- Volunteers
- 20 people
- Sponsor
- Kleber Paiva Duarte
Deafness, Hearing Loss
Children's Bilateral Cochlear Implantation in Finland
The purpose of this study is to evaluate short and long term outcomes (benefits and side-effects) of bilateral cochlear implantation and bilateral hearing aid rehabilitation in Finnish children.
- Trial name
- FinBiCI (NCT00960102)
- Testing
- cochlear implant, hearing aid
- Where
- 5 sites in Finland
- Volunteers
- 40 people
- Sponsor
- Kuopio University Hospital
Infertility, Female, Infertility of Uterine Origin
Progesterone Levels and Endometrial Compaction in Frozen-Thawed Embryo Transfer Cycles
This study is intended to determine whether there is a correlation between endometrial compaction and serum progesterone levels on the day of frozen embryo transfers by using transvaginal sonography for the endometrial assessment.
- Conditions
- Infertility, Female, Infertility of Uterine Origin, Implantation; Placenta
- Trial name
- NCT04554654
- Testing
- transvaginal ultrasound,
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cem Demirel
Coronary Artery Disease
Serial OCT Evaluation of Tissue Coverage in Patients Submitted to Inspiron Drug Eluting Stent Implantation
Prospective, multicentric, single-arm study to evaluate fast and effective tissue repair in patients undergone percutaneous coronary intervention with drug eluting stent Inspiron.
- Trial name
- REPAIR (NCT03269461)
- Testing
- Angiography and Optical Coherence Tomography evaluations
- Where
- 5 sites in Brazil
- Volunteers
- 60 people
- Sponsor
- Scitech Produtos Medicos SA
Coronary Heart Disease, Diabetes Mellitus
Comparison of Diabetes Mellitus and Non-diabetes Mellitus Patients for DES Surface COVERage by OCT
Diabetic patients are prone to a diffuse and rapidly progressive form of atherosclerosis. Both clinical and angiographic outcomes following percutaneous coronary intervention (PCI) are poor in patients with DM compared with those…
- Trial name
- DM-COVER (NCT01021930)
- Testing
- Polymer-based sirolimus-eluting stent(Cypher stent ) and Polymer-free paclitaxel-eluting stent (YinYi stent)
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Harbin Medical University
Aortic Stenosis, Nursing Caries
The Effect of Education and Follow-up Program in Patients Undergoing TAVI
Aortic stenosis is a progressive disease that affects approximately 3% of adults aged 75 and over. If left untreated, the mortality rate of aortic stenosis, which becomes symptomatic in a short time, is 50% in the first year…
- Trial name
- NCT05625269
- Testing
- Education
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Dokuz Eylul University
Presbyopia, Refractive Errors
Comparison of Premium Monovision and Bilateral Implantation of Trifocal Diffractive Intraocular Lenses
Primary objective of this study is to compare two presbyopia correction surgical techniques, specificaly premium monovision, in which the dominant eye is corrected with an extended depth of field intraocular lens and the…
- Conditions
- Presbyopia, Refractive Errors, Cataract
- Trial name
- NCT05494177
- Testing
- bUDVA, bUIRA, bUNRA, bUICPS, bUNCPS, Contrast sensitivity
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Democritus University of Thrace
Cataract, Intraocular Lens Complication
Functional IOL Implantation in Patients With Epiretinal Membrane
We have designed this prospective study to evaluate macular involvement and epiretinal membrane (ERM) grading by OCT in eyes with ERM and to compare clinical outcomes after implantation of Enhance IOL with standard monofocal IOL…
- Conditions
- Cataract, Intraocular Lens Complication, Epiretinal Membrane
- Trial name
- NCT06719739
- Testing
- Intraocular lens implantation
- Where
- 2 sites in China
- Volunteers
- 90 people
- Sponsor
- Eye & ENT Hospital of Fudan University
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