Clinical trials: EMBRYO IMPLANTATION
Posterior Synechiae of Iris
Mydriatic Drops After Combined Surgery
The study goal is to evaluate the influence of mydriatic drops on the development of posterior synechia after combined cataract and vitrectomy surgery.
- Trial name
- NCT05614622
- Testing
- Cyclopentolate Hydrochloride 1.0% eye drops
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Coronary Artery Disease
OPTIMIZE PCI: Multicenter Randomized Trial of OCT Compared to IVUS and Angiography to Guide Coronary Stent Implantation
The objective of this clinical investigation is to demonstrate the safety and efficacy of an OCT guided strategy for stent implantation
- Trial name
- ILUMIEN III (NCT02471586)
- Testing
- Coronary PCI guided by IVUS, Coronary PCI guided by OCT, Coronary PCI guided by Angiography
- Where
- 29 sites in United States, Belgium and 6 more
- Volunteers
- 450 people
- Sponsor
- Abbott Medical Devices
Malignant Glioma, Neoplasms
Antisense102: Pilot Immunotherapy for Newly Diagnosed Malignant Glioma
This human Phase 1 trial is a continuation of a Phase 1 trial which enrolled patients with recurrent gliomas (#TJU-14379-101) and which was designed after a previously conducted Phase 1 human trial at our institution.
- Trial name
- NCT02507583
- Testing
- IGF-1R/AS ODN; Surgery with tissue harvest and implantation 20 diffusion chambers in the rectus sheath with IGF-1R/AS ODN within 24 hours of craniotomy, implanted for 48 hours.
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- david andrews
High Myopia
Changes of the Corneal Endothelial Cell Count After Artisan Phakic Intraocular Lens Implantation
the investigator will evaluate the change in endothelial cell count in eyes implanted with the iris-claw phakic Artisan lens for treatment of moderate to high myopia using specular microscopy
- Trial name
- NCT03266354
- Testing
- specular microscopy before and after Artisan PIOL
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Assiut University
End-stage Renal Disease, Kidney Failure, Chronic
Safety and Efficacy of a Vascular Prosthesis for Hemodialysis Access in Patients With End-Stage Renal Disease
The purpose of this study is to assess the safety and efficacy of a novel, tissue-engineered vascular prosthesis, the Human Acellular Vascular Graft, HAVG.
- Trial name
- NCT01840956
- Testing
- HAVG
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- Humacyte, Inc.
Coronary Artery Disease
Safety and Efficacy of POT PTCA Balloon Dilatation Catheter for the Optimal Dilation After DES Implantation
The objective of this randomized control trial is to gain clinical insight on the use of POT PTCA balloon dilatation catheter for the optimal dilation after drug-eluting stent implantation.
- Trial name
- POT-DES (NCT05368129)
- Testing
- Balloon dilation
- Where
- China
- Volunteers
- 48 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Pain, Patient Satisfaction
Patient-controlled Sedation in Port Implantation (PACSPI-1)
The purpose of this prospective, observational study is to assess the feasibility of patient-controlled sedation (PCS) for implantation of subcutaneous venous ports (SVP).
- Trial name
- PACSPI-1 (NCT04631393)
- Testing
- Propofol Alfentanil
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Stefanie Seifert
Clinical Pregnancy After Single Embryo Transfer
Embryo Selection by Time Lapse Monitoring for Single Embryo Transfer ("SET")
A multiple pregnancy is an undesired outcome of assisted reproduction. Current embryo selection technologies are inefficient in identifying the embryo with the highest implantation potential.
- Trial name
- NCT01694641
- Testing
- time-lapse morphokinetic evaluation
- Where
- 2 sites in Hungary
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Dunamenti REK Istenhegyi IVF Center
Low-Flow, Low-Gradient Aortic Stenosis
Anatomic Stenosis Severity as a Prognostic Marker in Patients With Low-Flow Low-Gradient Aortic Stenosis Undergoing TAVI
The ATLAS TAVI Registry is a retrospective, investigator-initiated, multicenter registry including patients, who underwent Transcatheter Aortic Valve Implantation (TAVI) for classical or paradoxical low-flow, low-gradient aortic…
- Trial name
- ATLAS TAVI (NCT04914481)
- Where
- 11 sites in Canada, Denmark and 5 more
- Volunteers
- 1,500 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Vision Disorders
Modification in Cortical Activation in Pseudophakic Patients With Visual Difficulties After a Multifocal Implantation
This study will highlight differences in cortical activation between asymptomatic and symptomatic patients.
- Trial name
- PlainteIMF (NCT02529098)
- Testing
- fMRI
- Where
- France
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Pregnancy, Fertility
Prognostic Value of PIF Detection in Embryo Culture Media Correlation With Pregnancy Outcome
PIF: biomarker of successful implantation To overcome the poor reproductive potential of embryos generated during in vitro fertilization cycles and the lack of markers enabling the identification of the most competent ones, it is…
- Trial name
- PIF-SET1 (NCT01803893)
- Where
- 5 sites in United States, France and 1 more
- Volunteers
- 500 people
- Sponsor
- BioIncept LLC
Corneal Astigmatism in Cataract Patients and Previous DALK
Effectiveness of Toric Intraocular Lenses for Treating Corneal Astigmatism in Patients With Cataract and Previous DALK
the purpose of this study was to assess the efficacy of custom made toric intraocular lens implantation in patients with simultaneous post-DALK high corneal astigmatism and cataract.
- Trial name
- NCT03398109
- Testing
- Customized toric IOL for post-DALK atigmatism
- Volunteers
- 10 people
- Sponsor
- Fondazione G.B. Bietti, IRCCS
Acute Myocardial Infarction, Heart Failure
"ESTIMATION Study" for Endocardial Mesenchymal Stem Cells Implantation in Patients After Acute Myocardial Infarction
The investigators hypothesised that endocardial stem cells implantation following after percutaneous coronary intervention (PCI) could reduce the scar formation and increase reverse remodeling in patients with primary acute…
- Trial name
- ESTIMATION (NCT01394432)
- Where
- Russia
- Volunteers
- 50 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Virtual Reality, Medical Device
Effect of Virtual Reality on Patient's Comfort During Cardiac Electronic Device Implantation.
The purpose of this study is to assess the effect on patient's comfort of a virtual reality experience during a procedure of cardiac electronic device implantation under local anesthesia.
- Conditions
- Virtual Reality, Medical Device, Local Anesthesia, Pain
- Trial name
- NCT06346132
- Testing
- Virtual reality application
- Where
- Switzerland
- Volunteers
- 150 people
- Sponsor
- Schlotterbeck Hervé
Periprosthetic Aortic Valve Regurgitation After TAVI
Edwards SAPIEN-3 Periprosthetic Leakage Evaluation Versus Medtronic CoreValve in Transfemoral Aortic Valve Implantation
Transcatheter aortic valve replacement (TAVR) is a good alternative treatment for patients with severe aortic valve stenosis with similar mid-term success rates as compared to surgery.
- Trial name
- ELECT (NCT01982032)
- Testing
- Transcatheter aortic valve replacement, Medtronic CoreValve system, Edwards SAPIEN bioprosthesis
- Where
- Netherlands
- Volunteers
- 56 people
- Sponsor
- UMC Utrecht
Chronic Spinal Cord Injury
RESTORES Trial: RESToration Of Rehabilitative Function With Epidural Spinal Stimulation
Spinal Cord Injury (SCI), being a devastating diagnosis, has little to no recovery which leads to a long-standing of debilitating impairment for affected patients.
- Trial name
- RS-01 (NCT05644171)
- Testing
- RESToration Of Rehabilitative function with Epidural spinal Stimulation
- Where
- Singapore
- Volunteers
- 18 people
- Sponsor
- National Neuroscience Institute
Acute Coronary Syndromes (ACS), Chronic Coronary Syndrome
Starring Optical Coherence Tomography During Percutaneous Coronary Intervention Guidance
The starring optical coherence tomography during percutaneous coronary intervention guidance (OCT-AGEM) registry aims to evaluate the clinical impact of intra-procedural optical coherence tomography (OCT) in coronary…
- Conditions
- Acute Coronary Syndromes (ACS), Chronic Coronary Syndrome, MINOCA, INOCA (Ischemia With Non Obstructive Coronary Artery Disease)
- Trial name
- OCT-AGEM (NCT07182799)
- Testing
- Plaque vulnerability assessment, Stent implantation optimization
- Where
- Italy
- Volunteers
- 3,200 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Bone Healing, Augmentation
Healing After Augmentation of Alveolar Ridge Using Collagen Membrane
One of the prerequisites for successful prosthetic implant therapy of patients is achieving the initial stability of the embedded implant, which largely depends on the width alveolar ridge, at the place of its installation.
- Conditions
- Bone Healing, Augmentation, Augmentation, Alveolar Ridge
- Trial name
- NCT06885983
- Testing
- implant placement, Guided bone regeneration
- Where
- Serbia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Belgrade
Luteal Phase, Biomarkers
Early Pregnancy Cohort and Preimplantation Factor
Miscarriage is a common event associated with severe psychological and social morbidity, further tormenting in women suffering recurrent pregnancy loss (RPL) by at least three consecutive losses.
- Conditions
- Luteal Phase, Biomarkers, Abortion, Spontaneous, Abortion, Habitual
- Trial name
- PEP-cohort (NCT02761772)
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Nordsjaellands Hospital
Cochlear Implant, Severe to Very Severe Sensorineural Hearing Loss
Epidemiological Survey on the Current Status of Cochlear Implantation in China
Cochlear implantation is an effective intervention for patients with severe to very severe sensorineural hearing loss. By the beginning of 2026, the total number of cochlear implants in China was about 180000.
- Trial name
- NCT07821281
- Testing
- Cochlear Implant
- Volunteers
- 180,000 people
- Sponsor
- Chinese PLA General Hospital
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