Clinical trials: EMBRYO IMPLANTATION
Bradycardia, Brady-tachy Syndrome
Reduction Or Elimination Of Radiation During Implantation of Cardiac Devices Using Ultrasound
Specialized equipment is required to put pacemakers in the heart. This requires use of radiation to see the wires or leads being implanted in the heart.
- Trial name
- RADICAL USE (NCT04858698)
- Testing
- Ultrasound / Echocardiography
- Where
- Canada
- Volunteers
- 66 people
- Sponsor
- Habib Khan
Recurrent Implantation Failure
ERA in Young Primary Infertile RIF Patients
This study aims to evaluate the clinical efficacy of transcriptome-based endometrial receptivity analysis (tb-ERA) and investigate the molecular mechanisms of abnormal receptivity in young women with unexplained recurrent…
- Trial name
- ERA (NCT07767240)
- Testing
- tb-ERA and personalized embryo transfer
- Where
- China
- Volunteers
- 400 people
- Sponsor
- ShangHai Ji Ai Genetics & IVF Institute
Infertility
Intrauterine Human Chorionic Gonadotrophins (hCG) and Endometrial Treg Cells
Intrauterine injection of hCG around the time of implantation may increase endometrial Treg cells and improve implantation. It has been demonstrated that regulatory T cells expand during pregnancy.
- Trial name
- NCT01064219
- Testing
- human chorionic gonadotrophin
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- The Egyptian IVF-ET Center
Repeated Embryo Implantation Failure, Recurrent Miscarriage
Immune Profile Analysis and Biomarker Identification in Women With Repeated Implantation Failure or Unexplained Recurrent Spontaneous Miscarriage
Implantation is a determining step in human reproduction which requires the transition from a pro-inflammatory state to an anti-inflammatory state allowing the implantation of a competent embryo within a receptive endometrium…
- Conditions
- Repeated Embryo Implantation Failure, Recurrent Miscarriage, Immune System
- Trial name
- ERIM (NCT05648136)
- Testing
- blood sample
- Where
- France
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
IVF
Dual Trigger, Urinary HCG or Recombinant HCG, Which is the Best !?
a comparative study among dual trigger, urinary HCG and recombinant HCG regarding the outcome of ICSI- antagonist cycles
- Trial name
- NCT04265495
- Where
- Bahrain
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Al Baraka Fertility Hospital
Hip Osteoarthritis
Autologous Chondrocyte Intra-articular Implantation in Patients With Severe Hip Osteoarthritis
Hip osteoarthritis is degeneration of hip cartilage and inflammation of subchondral bone and soft tissue linings. Patients have pain, stiffness, swelling, and difficulty walking.
- Trial name
- NCT01500811
- Testing
- cell injection
- Where
- Iran
- Volunteers
- 6 people
- Sponsor
- Royan Institute
Transcatheter Aortic Valve Implantation Prosnosis and Complications
Tryptase Level as a Marker of Complications in Transcatheter Aortic Valve Replacement
An association between mast cells and outcomes of patients undergoing transcatheter aortic valve replacement (TAVR) has not been studied to our knowledge.
- Trial name
- TAVR (NCT03047681)
- Testing
- venous blood withdrawl
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Mitral Insufficiency, Mitral Stenosis
Polish Transcatheter Transfemoral Mitral Valve-in-Valve Implantation (Mitral ViV) Registry
In recent years increasing number of mitral bioprosthesis implantation, especially in elderly population, is observed. Bioprosthetic valves are associated with a lower risk of thrombotic and bleeding adverse events compared with…
- Conditions
- Mitral Insufficiency, Mitral Stenosis, Mitral Stenosis With Insufficiency, Heart Failure
- Trial name
- NCT05625607
- Testing
- Transcatheter mitral valve-in-valve implantation
- Where
- 7 sites in Poland
- Volunteers
- 100 people
- Sponsor
- Medical University of Warsaw
Pacemaker DDD, Cardiopulmonary Endurance
Effect of Standardized Exercise on Cardiopulmonary Function in Patients With Permanent Pacemaker Implantation
The purpose of this study is to observe the changes of cardiopulmonary endurance in patients with pacemaker implantation after long-term exercise, to explore the significance of exercise on patients with pacemaker implantation…
- Trial name
- NCT04957771
- Testing
- Supervise and guide regular exercise
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Peking University Third Hospital
Primary Open Angle Glaucoma
Effect of Xen Implantation on the Aqueous Humor Proteome
The purpose of this study is to determine how the aqueous humor proteome changes after implantation of a Xen microstent for treatment of glaucoma.
- Trial name
- NCT04141865
- Testing
- Xen, Aqueous shunt
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Price Vision Group
Glaucoma, Open-Angle
Retrospective Review of Xen Gel Stent Implantation With Open vs. Closed Conjunctiva Approach
To measure surgical success of open vs closed conjunctiva with Xen implantation.
- Trial name
- NCT04406467
- Testing
- Xen Gel Stent
- Where
- United States
- Volunteers
- 137 people
- Sponsor
- Johns Hopkins University
Keratoconus
Pentacam Findings After Implantation of Intrastromal Corneal Rings in Keratoconus.
keratoconus is a progressive corneal ectatic disease characterized by paraxial stromal thinning and weakening, resulting in irregular astigmatism, corneal protrusion, and distortion of the anterior corneal surface.
- Trial name
- NCT04562064
- Testing
- corneal tomography scans
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Assiut University
Edentulism, Dental Implantation, Endosseous
Subcrestal vs Juxtacrestal PRAMA Implants With Variable Necks
The goal of this clinical trial is to understand how different implant neck designs and placement depths affect the surrounding bone and peri-implant tissue (the tissue around a dental implant) in adults who need implants in the…
- Conditions
- Edentulism, Dental Implantation, Endosseous, Marginal Bone Loss, Periimplant Bone Loss
- Trial name
- NCT07107464
- Testing
- Short Neck Implant - Crestal Placement, Standard Neck Implant - 1 mm Subcrestal Placement, Long Neck Implant - 2 mm Subcrestal Placement
- Where
- Cuba
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- ARDEC Academy
Cerebral Palsy
Safety and Effectiveness of Autologous Adipose Tissue Derived Mesenchymal Stem Cell Implantation in Patients With CP
Safety and Effectiveness of Autologous Adipose Tissue Derived mesenchymal Stem Cell Implantation in Patients with CP
- Trial name
- CP (NCT03979898)
- Testing
- ASTROSTEM
- Where
- South Korea
- Volunteers
- 1 people
- Sponsor
- R-Bio
Any Patient Who Fulfills the Inclusion Criteria to be Implanted With a Dual Chamber Pacemaker Maybe Included in the Study as Per ACC/AHA Guidelines
Comparison of AAIsafeR and DDD Modes in Non-selected Patients
1 Purpose In patients with sinus node dysfunction (SND), the use of AAI mode is rare. In paroxysmal high-degree or complete atrio-ventricular (AV) block, paroxysmal vagally-mediated bradycardia, single chamber atrial pacemakers…
- Trial name
- CAN-SAVE R (NCT01219621)
- Testing
- Symphony Dual Chamber Rate Responsive Device
- Where
- 10 sites in Canada
- Volunteers
- 450 people
- Sponsor
- Sorin Group Canada
Coronary Artery Disease, Aortic Valve Stenosis
Prospective Registry of Patients Undergoing Cardiac CT With NAEOTOM Alpha PCD-CT Before TAVI Procedure
The clinical and demographic characteristics of patients undergoing transcatheter aortic valve implantation (TAVI) pose unique challenges for coronary computed tomography (CT) imaging, as this patient population is mainly…
- Conditions
- Coronary Artery Disease, Aortic Valve Stenosis, Tomography, X-Ray Computed
- Trial name
- Alpha Registry (NCT07016477)
- Testing
- Ultra-High Resolution Photon Counting Detector Coronary Computed Tomography Angiography
- Where
- 7 sites in United States, Germany and 3 more
- Volunteers
- 1,000 people
- Sponsor
- Semmelweis University
Major Adverse Cardiovascular and Cerebrovascular Events (MACCE)
Observational Prospective Study OPTIMA II - Follow-up
The current follow-up study was planned to reveal the rates of Major Adverse Cardiovascular and Cerebrovascular Events (MACCE) during 4-year follow-up in patients participated in OPTIMA study.
- Trial name
- OPTIMAII (NCT02099565)
- Where
- Russia
- Volunteers
- 572 people
- Sponsor
- AstraZeneca
Ascites, Paracentesis
Medical-economic Evaluation of the Care of Refractory Ascites by Implantation of Alfapump® Device in Cirrhotic Patients
The hypothesis is that the Alfapump® strategy would be more effective in terms of QALYs generated , and that the cost of Alfapump® device and its implantation will be totally or partially offset by the reduction in the number of…
- Conditions
- Ascites, Paracentesis, Cirrhosis
- Trial name
- ARIAPUMP (NCT03506893)
- Testing
- Alphapump, Ascites puncture
- Where
- 10 sites in France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Grenoble
Calcific Aortic Valve Disease, Inflammation
Impact of TAVI on the Gut Microbiota and Its Metabolites
Aortic stenosis is a common heart valve disease in older adults. It occurs when the aortic valve becomes narrowed, making it harder for blood to flow from the heart to the rest of the body.
- Conditions
- Calcific Aortic Valve Disease, Inflammation, Dysbiosis, TAVI
- Trial name
- Swiss-GUT-TAVI (NCT07565077)
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Kidney Transplant; Complications, Kidney Transplant Infection
Pediatric Kidney Transplantation, Ureteroneocystostomy Techniques
In this study the researchers want to retrospectively compare non-refluxing ureteroneocystostomy (UNC techniques to reflux UNC techniques in paediatric kidney recipients with regard to urinary tract infections and uteral…
- Conditions
- Kidney Transplant; Complications, Kidney Transplant Infection, Kidney Transplant Failure and Rejection
- Trial name
- TUIKIT (NCT05397821)
- Testing
- UNC technique
- Where
- Netherlands
- Volunteers
- 398 people
- Sponsor
- Radboud University Medical Center
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