Clinical trials: EMBRYO IMPLANTATION
Adolescent Idiopathic Scoliosis
PMS Evaluation of Safety and Efficacy of the MID-C System 5 Years Post-implantation in AIS
The ApiFix MID-C System is a unidirectional expandable rod, designed to be connected unilaterally to the spine via 2 anchor points on the concave side of a scoliotic deformity above and below the apex of the major curvature to…
- Trial name
- NCT04684927
- Testing
- MID-C System -Minimal invasive deformity correction system for the treatment of AIS
- Sponsor
- Apifix
Live Birth Delivery Rate
Pre-Implantation Genetic Screening in Women Under the Age of 36 Years With Single Embryo Transfer
BACKGROUND: Single-embryo transfer is a well-accepted strategy to avoid multiple pregnancies in an assisted reproductive technology programme. The selection of the embryo with the highest implantation potential is a crucial step.
- Trial name
- NCT00670059
- Testing
- single embryo transfer without aneuploidy screening, single embryo transfer with aneuploidy screening
- Where
- Belgium
- Volunteers
- 240 people
- Sponsor
- Vrije Universiteit Brussel
Placental Development Pregnancy Outcome
Peri-implantation Abstinence and Placental Health
This study examined whether avoiding sexual intercourse during the time when a fertilized egg may attach to the uterus affects placental development and pregnancy outcomes.
- Trial name
- NCT07843173
- Testing
- Couples were instructed to avoid sexual intercourse for 14 days after ovulation during each study cycle, covering the expected peri-implantation period.
- Where
- Malaysia
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Ventricular Tachyarrhythmia
NORDIC ICD (Cardioverter Defibrillator Implantation) Trial
The purpose of the NORDIC ICD study is to evaluate whether ICD implantation without intra-operative DF testing is non-inferior to ICD implantation with intra-operative DF testing regarding the efficacy of the first ICD shock for…
- Trial name
- NCT01282918
- Testing
- ICD implantation w/o DF test, ICD implantation with DF test
- Where
- 2 sites in Germany, Sweden
- Volunteers
- 1,077 people
- Sponsor
- Biotronik SE & Co. KG
Acute Myocardial Infarction, Coronary Syndrome
Antiplatelet Therapy Following Stent Implantation
Coronary artery stents, particularly drug-eluting stents (DES), are used in the majority of patients who undergo percutaneous coronary intervention (PCI) to improve symptoms in patients with obstructive coronary artery disease.
- Conditions
- Acute Myocardial Infarction, Coronary Syndrome, Angina, Unstable
- Trial name
- Anti-Clot (NCT02051361)
- Where
- Greece
- Volunteers
- 900 people
- Sponsor
- Elpen Pharmaceutical Co. Inc.
Syncope, Bradycardia
Registry of Device Implantation
The implantable device therapy for cardiac arrhythmias has been an established therapy, and one of the common standard procedures in cardiac clinical practice.
- Conditions
- Syncope, Bradycardia, Tachycardia, Sudden Cardiac Death
- Trial name
- NCT03360227
- Testing
- implantation of cardiac devices
- Where
- Germany
- Volunteers
- 2,000 people
- Sponsor
- Klinik für Kardiologie, Pneumologie und Angiologie
Coronary Artery Disease
Comparison Between P2Y12 Antagonist Monotherapy and Dual Antiplatelet Therapy After DES
To compare the efficacy and safety of clopidogrel monotherapy versus aspirin plus P2Y12 antagonist following 3-month of DAPT in patients undergoing PCI with DES.
- Trial name
- SMART-CHOICE (NCT02079194)
- Testing
- P2Y12 antagonist monotherapy, aspirin plus P2Y12 antagonist
- Where
- South Korea
- Volunteers
- 3,000 people
- Sponsor
- Samsung Medical Center
Female Infertility, Oocyte Competence
Adipose Stem Cell Mitochondria Supplementation to Oocytes (ASCENT)
The purpose of this study is to investigate the potential of autologous adipose stem cell (ASC) mitochondrial transfer (ASCENT) to oocytes along with intracytoplasmic sperm injection (ICSI)as a means of enhancing embryo…
- Conditions
- Female Infertility, Oocyte Competence, Mitochondria, Recurent Implantation Failures
- Trial name
- NCT07066267
- Testing
- Experimental
- Where
- Sri Lanka
- Volunteers
- 20 people
- Sponsor
- Sunkaky Medical Cooperation
Pregnancy Related
Transcriptome Profiling and Endometrial Receptivity
The aim of this study is to correlate and identify the biochemical markers which may reflect WOI. Blood samples will be collected and endometrial biopsy will be performed at particular time points.
- Trial name
- NCT03925311
- Testing
- endometrial biopsy and blood sampling
- Where
- Hong Kong
- Volunteers
- 220 people
- Sponsor
- Chinese University of Hong Kong
Abdominal Aortic Aneurysm, Endoleak
AneuFix - Prophylactic Sac Filling
This study is set up to assess the feasibility and safety of the clinical procedure using AneuFix in a prophylactic setting at the time of EVAR endograft implantation.
- Trial name
- NCT04307992
- Testing
- Prophylactic sac filling with AneuFix
- Where
- 3 sites in Netherlands
- Volunteers
- 20 people
- Sponsor
- TripleMed B.V.
Infertility
Prospective Observational Study of Peri-implantation Serum hCG Levels
The purpose of this study is to prospectively define a set of data suitable for developing models of pregnancy viability. Those models will be based on serum hCG concentration measured during the peri-implantation period in…
- Trial name
- NCT01184469
- Where
- United States
- Volunteers
- 451 people, healthy volunteers welcome
- Sponsor
- Bruce Shapiro M.D.
Aortic Valve Stenosis
Engager Align Post-market Clinical Study
Purpose To characterize the safety and clinical benefit of the Engager Transcatheter Aortic Valve Implantation System in a real world environment.
- Trial name
- NCT02149654
- Testing
- Engager Transcatheter Aortic Valve Implantation System
- Where
- Netherlands
- Volunteers
- 27 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Autoimmunity, Inguinal Hernia
ASIA-Mesh: a Pilot Study for Diagnostics and Treatment on ASIA Syndrome Caused by Polypropylene Mesh Implantation
In the present pilot study, a possible relation between the implantation of PP mesh for inguinal hernia, vaginal prolapse and SUI repair and subsequent systemic auto-immune complaints is investigated by testing immunologic and…
- Conditions
- Autoimmunity, Inguinal Hernia, Stress Urinary Incontinence, Pelvic Organ Prolapse
- Trial name
- NCT06363903
- Testing
- mesh allergy test, blood tests, Mesh removal
- Where
- 3 sites in Netherlands
- Volunteers
- 50 people
- Sponsor
- Maxima Medical Center
Transcatheter Aortic Valve Implantation
Investigation of the NVT ALLEGRA Plus THV System in Patients With Severe Aortic Stenosis or Failed Surgical Aortic Bioprosthesis
The EMPIRE II study evaluates the safety and performance of the entire ALLEGRA THV System. The primary safety endpoint is composite of all-cause mortality or stroke rates at 12 months.
- Trial name
- EMPIRE-II (NCT05804903)
- Testing
- (ALLEGRA Plus Transcatheter Heart Valve) TAVI in severe calcified aortic stenosis or in failed surgical aortic bioprosthesis
- Where
- 7 sites in Finland, Germany and 3 more
- Volunteers
- 177 people
- Sponsor
- NVT GmbH
Liver Disease, Liver Cirrhosis
Hepatocyte Matrix Implant Study
This clinical investigation of the hepatocyte matrix implant is an evaluation blinded non-randomized and monocentric pilot study of Phase I, which is conducted as a therapeutic investigation.
- Trial name
- HMI (NCT00935454)
- Testing
- Hepatocyte matrix implantation
- Where
- Switzerland
- Volunteers
- 10 people
- Sponsor
- Baermed
Stromal Keratitis
Stromal Lenticule Implantation for Management of Herpetic Stromal Keratitis
The aim of this study is the evaluation of corneal transparency and improvement of visual acuity in patients with herpetic stromal keratitis.
- Trial name
- Relex-Smile (NCT05156151)
- Testing
- Relex-Smile
- Where
- Kosovo
- Volunteers
- 35 people
- Sponsor
- Eye Hospital Pristina Kosovo
Coronary Artery Disease, Coronary Disease
Late Stent Strut Apposition and Coverage After Drug-Eluting Stent Implantation by OCT in Patients With AMI
The purpose of this study is to evaluate the incidence of late incomplete stent apposition (ISA) and un-coverage by optical coherence tomography (OCT) following everolimus-eluting stent (EES) with bioabsorbable polymer (SYNERGY™…
- Conditions
- Coronary Artery Disease, Coronary Disease, Myocardial Ischemia, Arterial Occlusive Diseases
- Trial name
- NCT02770651
- Testing
- Everolimus-Eluting stent, Zotarolimus-Eluting stent
- Where
- South Korea
- Volunteers
- 69 people
- Sponsor
- Keimyung University Dongsan Medical Center
Cataract
Recommendations for Monitoring Clinical Experience Following Implantation of the AcrySof® Toric
To allow surgeons to obtain clinical experience on the postoperative uncorrected and best distance corrected visual acuities (UCVA and BDCVA) and corneal and refractive cylinder of the AcrySof Toric IOL.
- Trial name
- NCT00761488
- Testing
- AcrySof® Toric IOL
- Where
- United States
- Sponsor
- Alcon Research
Corneal Transplantation, Corneal Graft Rejection
Study to Assess LX201 for Prevention of Corneal Allograft Rejection or Graft Failure in Subjects Who Have Experienced One or More Rejection Episodes Following Penetrating Keratoplasty
This study will evaluate the use of LX201 to prevent future graft rejection episodes and/or graft failure in patients who have undergone corneal transplantation and who have recently experienced a rejection episode due to an…
- Trial name
- NCT00447642
- Testing
- LX201
- Where
- 30 sites in United States, Germany
- Volunteers
- 122 people
- Sponsor
- Lux Biosciences, Inc.
Cataract
Evaluation of Quality of Vision and Visual Outcomes With Bilateral Implantation of the Clareon PanOptix Intraocular Lens
To evaluate visual outcomes and quality of vision following bilateral implantation of the Clareon PanOptix intraocular lens (IOL) targeted for emmetropia.
- Trial name
- NCT05518539
- Testing
- The Clareon™ PanOptix™ Trifocal (toric and non-toric models)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Newsom Eye & Laser Center
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