Clinical trials: EMBRYO IMPLANTATION
Aortic Stenosis
Videodensitometric Angiographic Assessment of AR in the Cath-lab for Intraprocedural Guidance of TAVI in CHINA
This clinical trial, a prospective, randomized, multicenter study, assigns patients to either videodensitometry-guided TAVI or conventional TTE/TEE-guided TAVI (stand of care), with the primary endpoint being regurgitation…
- Trial name
- NCT06891079
- Testing
- Videodensitometric guided, Stand of care guided
- Where
- 2 sites in China
- Volunteers
- 320 people
- Sponsor
- Xijing Hospital
Osseointegrated Dental Implantation
Effect of Platelet-rich Factor on Implant Stability and Bone Resorption in the Lower Posterior Mandible
The main objective of this clinical trial study is to consider the effect of Platelet-Rich-Factor (PRF) on implant stability and marginal bone resorption around dental implants.
- Trial name
- NCT02349620
- Testing
- PRF
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- Reza Tabrizi
Percutaneous Transluminal Coronary Angioplasty
Quantitative Coronary Angiography Versus Imaging GUIDancE for Bioresorbable Vascular Scaffold Implantation
The purpose of this study is to compare clinical outcomes between QCA(quantitative coronary angiography)-guided and imaging-guided strategy in patients with native coronary artery disease undergoing Bioresorbable Vascular…
- Trial name
- GUIDE-BVS (NCT02831218)
- Testing
- QCA and Aspirin, QCA and Clopidogrel, Imaging guided and Aspirin
- Where
- South Korea
- Volunteers
- 70 people
- Sponsor
- Seung-Jung Park
Cryopreservation, Embryo Implantation
Optimal Length of Progesterone Supplementation Before the Transfer of Cryopreserved(Frozen)-Thawed Embryos in an Artificial Cycle With Exogenous Estrogen and Progesterone.
The aim of the study is to determine whether 5 or 7 days of progesterone supplementation before transfer of a day 5 cryopreserved thawed embryos in an artificial cycle results in a significant higher pregnancy rate.
- Conditions
- Cryopreservation, Embryo Implantation, Progesteron
- Trial name
- PROFETA-5 (NCT02032797)
- Testing
- Progesterone
- Where
- Belgium
- Volunteers
- 300 people
- Sponsor
- Universitair Ziekenhuis Brussel
Atrial Fibrillation
Left Atrial Appendage (LAA) Occluders After Catheter Ablation of Atrial Fibrillation
The primary objective of this study is to assess combined end point (All stroke, Systemic embolism, Cardiovascular death) between two groups.
- Trial name
- NCT01695824
- Testing
- LAA occluder, RFA ablation, Warfarin
- Where
- Russia
- Volunteers
- 96 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Cataract
PureSee/Odyssey Mix-and-Match IOL
Observational, prospective, bilateral, single-arm investigator-initiated study. Single cohort at one site: TECNIS PureSee intraocular lens in the dominant eye and TECNIS Odyssey intraocular lens in the non-dominant eye.
- Trial name
- NCT07898917
- Testing
- Mix-and-match PureSee/Odyssey cohort
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Gainesville Eye Associates
Renal Function, Renal Injury
Analysis of Remote-ischemic Preconditioning Effects on Kidney Function
Patients with impaired renal function are at elevated risk for development of acute kidney injury (AKI). AKI is associated with increased risk for cardiovascular morbidity and mortality.
- Trial name
- RenPRO-TAVI (NCT01925235)
- Testing
- remote ischemic preconditioning
- Where
- Germany
- Volunteers
- 18 people
- Sponsor
- University of Cologne
Vascular Access Complication
A Retrospective Study Evaluating the Use of the SoloPath® Sheath in Reducing Vascular and Bleeding Complications
This study is a retrospective, single center data collection to assess bleeding and vascular complications associated with TAVI when a SoloPath® Balloon Expandable TransFemoral Introducer is used for vascular access.
- Trial name
- NCT02297308
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- Terumo Medical Corporation
Dental Implantation, Peri-Implant Soft Tissue Deficiency
Volume-Stable Collagen Matrix vs. Connective Tissue Graft for Peri-Implant Soft Tissue Defects
Peri-implant soft-tissue defects will be treated with either a volume-stable collagen matrix (VCMX; test group) or an autogenous connective tissue graft (CTG; control group) following implant placement in patients with a single…
- Conditions
- Dental Implantation, Peri-Implant Soft Tissue Deficiency, Soft Tissue Augmentation
- Trial name
- NCT07782125
- Testing
- Connective tissue graft, Volume-stable collagen matrix
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Ankara University
Hip Fracture
Safety and Efficacy of the WaisFix100i for Intracapsular Femoral Fracture Fixation
The purpose of this study is to determine the safety and efficacy of using WaisFix100i device for Intracapsular Femoral Fracture Fixation.
- Trial name
- NCT00521716
- Testing
- Intracapsular Femoral Fracture Fixation, WaisFix100i for Intracapsular Femoral Fracture Fixation
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- OrthoMediTec
Aortic Valve Disease
Long-Term Follow-up After the Autograft Aortic Valve Procedure (Ross Operation)
With the current knowledge of aortic valve replacement modalities, no specific recommendations can be given and the decision for a particular prosthesis or procedure is rather arbitrarily.
- Trial name
- NCT00708409
- Testing
- Cardiac valve surgery
- Where
- Germany
- Volunteers
- 1,800 people
- Sponsor
- University of Luebeck
Cataract
Visual Outcomes of Tecnis Symfony Opti-Blue EDOF Intraocular Lens (IOL)
Tecnis Symfony Optiblue EDOF IOL is the latest version of Tecnis Symfony IOL with a violet light filter (VLF), which blocks short-wavelength light and improves the quality of vision while minimizing visual disturbances.
- Trial name
- NCT06500416
- Testing
- Tecnis Symfony OptiBlue/ Tecnis Symfony OptiBlue toric IOL
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Coastal Eye Surgeons PLLC
Fertility Issues, Embryo Implantation
Rescue Progesterone Supplementation During Frozen Embryo Transfer
Endometrin is a progesterone supplement prescribed during in vitro fertilization (IVF) for preparation for embryo transfer. The usual dose of Endometrin is 100 mg two to three times per day in the form of an effervescent tablet…
- Conditions
- Fertility Issues, Embryo Implantation, Frozen Embryo Transfer
- Trial name
- P4R (NCT05555121)
- Testing
- Progesterone Effervescent Vaginal Tablet
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Clinique Ovo
Recurrent Implantation Failure, Infertility (IVF Patients)
Endometrial Immune Profile in Recurrent Implantation Failure
The goal of this observational study is to learn whether differences in the immune cells of the womb lining (endometrium) help explain why some women do not become pregnant despite several IVF attempts using good-quality embryos…
- Trial name
- NCT07848399
- Where
- United Kingdom
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- King's College London
Penile Prosthesis Infection, Penile Prosthesis; Complications, Infection or Inflammation
Minimally Invasive Scrotal Incision for Penile Prosthesis Implantation, Novel Technique.
The main goals of this study are to examine the superiority of this novel technique and its acceptance by patients with ED candidate for PPI and compare these results with data available in the literature for ordinary…
- Trial name
- PPI (NCT05558163)
- Testing
- transverse scrotal approach for PPI, penoscrotal approach for PPI
- Volunteers
- 200 people
- Sponsor
- Al-Azhar University
Non-valvular Atrial Fibrillation (NVAF), Thromboembolism
Stepwise vs Standard Anticoagulation for AF Patients Undergoing CIED Implantation (STEP-AF)
This is a multi-center, prospective, open-label, randomized controlled trial (STEP-AF) designed to evaluate the safety of a stepwise anticoagulation strategy compared with the guideline-recommended standard anticoagulation…
- Conditions
- Non-valvular Atrial Fibrillation (NVAF), Thromboembolism, Cardiac Implantable Electronic Device, Perioperative Bleeding
- Trial name
- STEP-AF (NCT07616414)
- Testing
- Stepwise Anticoagulation Regimen, Standard Anticoagulation Regimen
- Where
- China
- Volunteers
- 424 people
- Sponsor
- Fu Wai Hospital, Beijing, China
Pregnancy, Embryo Implantation
Administration of GnRH Antagonist to Oocyte Donation Recipients
This prospective and randomized study was performed to evaluate whether the replacement of GnRH agonist by a GnRH antagonist in oocyte donation recipients during endometrial preparation has any impact on pregnancy and…
- Trial name
- GnRH-Ovodon (NCT00635258)
- Testing
- triptorelin (Decapeptyl®, Ipsen Pharma, Barcelona, Spain), GnRH antagonist (Orgalutran®)
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Centro Ginecologia y Obstetricia.
Osteonecrosis of the Femoral Head
Study on Autologous Osteoblastic Cells Implantation to Early Stage Osteonecrosis of the Femoral Head
Non-traumatic osteonecrosis is a painful disorder of the hip characterized by a necrosis of the osteomedullary tissue, which leads to subchondral bone collapse and joint destruction.
- Trial name
- NCT01529008
- Testing
- Core decompression/PREOB® implantation
- Volunteers
- 68 people
- Sponsor
- Bone Therapeutics S.A
STEMI, STEMI (ST Elevation MI)
Pilot Study of IC14 (Atibuclimab), an Anti-CD14 Monoclonal Antibody, to Treat STEMI
Adults who have had an ST-elevation myocardial infarction and were treated with stent placement will receive an intravenous infusion of a monoclonal antibody in order to prevent further heart muscle damage.
- Conditions
- STEMI, STEMI (ST Elevation MI), STEMI - ST Elevation Myocardial Infarction (MI), Stent Implantation
- Trial name
- NCT06678074
- Testing
- Atibuclimab (IC14), 20 mg/kg intravenously, once
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Implicit Bioscience
Morbid Obesity
Post Implantation/Post Market Evaluation of the Swedish Adjustable Gastric Band
The purpose of the study is to evaluate the long term safety of the Swedish Adjustable Gastric Band (SAGB) in subjects with an SAGB in place.
- Trial name
- SAGB-PM (NCT00543140)
- Testing
- REALIZE™ Swedish Adjustable Gastric Band
- Where
- 8 sites in United States
- Volunteers
- 303 people
- Sponsor
- Ethicon Endo-Surgery
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