Clinical trials: EMBRYO IMPLANTATION
Thromboembolism, Bleeding
Anticoagulant After Implantation of Biological Aortic Valve Comparing With Aspirin
The optimal medical strategy for prevention of thromboembolic events after bioprosthetic aorta valve replacement (BAVR) remains controversial.
- Trial name
- NCT01452568
- Testing
- Aspirin, Warfarin
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Lens Implantation, Intraocular
Incidence of Glaucoma-related Adverse Events in Pediatric Secondary Intraocular Lens Implantation
To compare the incidence of glaucoma-related adverse events of in-the-bag versus ciliary-sulcus-fixed secondary intraocular lens (IOL) implantation in pediatric aphakia
- Trial name
- NCT05136950
- Testing
- Secondary in-the-bag IOL fixation, Secondary ciliary sulcus IOL fixation
- Where
- China
- Volunteers
- 228 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Cataract
Evaluation Of Bilateral Tecnis Multifocal Versus ReSTOR 3D Intraocular Lenses
The purpose of this study is to compare the visual outcomes with bilateral implantation of Tecnis MF and ReSTOR intraocular lenses (IOLs) 6 months post cataract surgery.
- Trial name
- NCT01061918
- Testing
- Tecnis MF, ReSTOR
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Innovative Medical
Deafness Unilateral
Cochlear Implantation for Young Single-sided Deaf Children
Children with profound sensorineural unilateral hearing loss (UHL) lag behind in spoken language, cognition, spatial hearing, and academic performance compared to normal hearing (NH) children.
- Trial name
- CICADE (NCT04738968)
- Testing
- Cochlear implant
- Where
- 4 sites in Belgium
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Symptomatic Aortic Stenosis
ACURATE TF™ Transfemoral Aortic Bioprosthesis for Implantation in Patients With Severe Aortic Stenosis:CE-approval Cohort
First clinical experience on the ACURATE TF™ Transfemoral Aortic Bioprosthesis Implantation in Patients with Severe Aortic Stenosis to collect human data pertaining to the safety and performance of the device from three different…
- Trial name
- NCT03003650
- Testing
- ACURATE TF™
- Where
- 6 sites in Brazil, Germany and 1 more
- Volunteers
- 89 people
- Sponsor
- Symetis SA
Subacute Myocardial Infarction
Study to Assess Safety & Effects of Autologous ADSCs During Recovery Phase of ST-Elevation MI Effects of Autologous ADSC Implantation During Subacute Recovery Phase of ST-Elevation Myocardial Infarction
The intent of this clinical study is to answer the questions: 1) Is the proposed treatment safe? and 2) Is treatment effective in improving cardiac function and clinical outcomes?
- Trial name
- NCT03272191
- Testing
- Liposuction and stem cell implantation
- Where
- United States
- Sponsor
- Ageless Regenerative Institute
Articular Cartilage Defect, Articular Cartilage Degeneration
Phase 3 Clinical Trial of CartiLife® in Korea
To evaluate the safety and efficacy of pellet-type extracellular matrix-associated autologous chondrocytes (CartiLife®) obtained by cultivating costal chondrocytes of the subject implanted into articular cartilage defects of the…
- Trial name
- NCT05051332
- Testing
- Autologous Chondrocyte Implantation (CartiLife®), Microfracture Surgery
- Where
- 18 sites in South Korea
- Volunteers
- 104 people
- Sponsor
- Biosolution Co., Ltd.
Parkinson's Disease, Dystonia
Use of Interventional MRI for Implantation of Deep Brain Stimulator Electrodes
The purpose of this study is to gather observational data on an already FDA-approved implantation technique for deep brain stimulation (DBS) in which the entire surgery is performed within an MRI scanner ("interventional MRI", or…
- Trial name
- iMRI (NCT00792532)
- Testing
- interventional MRI for implantation of DBS electrodes, DBS electrodes
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of California, San Francisco
Hearing Loss, Binaural, Cochlear Implantation
Mi2000 TICI Follow-up
This Post-Market Clinical Follow-up (PMCF) investigation aims to further collect evidence on safety and performance of the Mi2000 TICI.
- Trial name
- M2FU (NCT07902414)
- Testing
- Cochlear Implantation
- Where
- 6 sites in Austria, Belgium and 2 more
- Volunteers
- 36 people
- Sponsor
- MED-EL Elektromedizinische Geräte GmbH
Effect on Implantation and Pregnancy Rates
Effect of Seminal Plasma Insemination on Pregnancy Rates After IVF-ET
Seminal plasma insemination into the vaginal vault of patients undergoing IVF-ET increases uterine receptivity.
- Trial name
- NCT01809366
- Testing
- seminal plasma insemination
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Assaf-Harofeh Medical Center
Stroke, Hemiplegia
Clinical Study to Evaluate the Implantation of the ActiGait Drop Foot Stimulator System
The objective of this study is to evaluate the efficacy and safety of surgical procedure involving ActiGait - implantable drop foot stimulator.
- Trial name
- NCT01116466
- Testing
- ActiGait
- Volunteers
- 5 people
- Sponsor
- Otto Bock Healthcare Products GmbH
Patients With SAT or LT After Stent Implantation (PCI)
Molecular and Cellular Mechanisms of the In-stent-thrombosis
In-Stent-Thrombosis is a rare but serious complication after implantation of stents during PTCA.
- Trial name
- NCT00652015
- Where
- Germany
- Sponsor
- RWTH Aachen University
Aortic Stenosis, Mitral Regurgitation
Transcatheter Treatment for Combined Aortic and Mitral Valve Disease. The Aortic+Mitral TRAnsCatheter (AMTRAC) Valve Registry
an international multicentre registry designed to answer 3 clinical questions: 1. Describing the characteristics and outcomes of current patients undergoing aortic + mitral transcatheter heart valve procedures. 2.
- Trial name
- AMTRAC (NCT04031274)
- Testing
- TAVI, TMVR/r
- Where
- Israel
- Volunteers
- 10,000 people
- Sponsor
- Rabin Medical Center
Urinary Incontinence
Variation of Physical Activity, Measured by the Number of Steps Per Day, After Artificial Urinary Sphincter Implantation
The management of urinary incontinence seems to improve daily activities and the practice of physical activity, according to the literature.
- Trial name
- AP-SU (NCT04008108)
- Testing
- Activity sensor
- Where
- France
- Volunteers
- 45 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pacemaker Implantation for Sinus Node Disease
Evaluation of Pacemaker Algorithms to Avoid Unnecessary Right Ventricular Pacing
Unnecessary right ventricular pacing has been shown to be detrimental in recipients of implantable pacemaker or defibrillators. The ADVANTAGE study evaluates the efficacy of two pacemaker based algorithms (atrioventricular…
- Trial name
- ADVANTAGE (NCT01803217)
- Testing
- pacemaker programming to mode switch to atrial pacing versus atrioventricular hysteresis function
- Where
- 3 sites in Germany
- Volunteers
- 70 people
- Sponsor
- Deutsches Herzzentrum Muenchen
Coronary Artery Stenosis
COmplex BifuRcation Lesions: A Comparison Between the AXXESS Device and Culotte Stenting: An Optical Coherence Tomography (OCT) Study
The aim of this study is to compare vessel healing at 9 months using OCT imaging for two different treatment techniques for treating bifurcation lesions.
- Trial name
- COBRA (NCT00895791)
- Testing
- AXXESS Biolimus A9-eluting bifurcation stent, culotte stenting (Xience V)
- Where
- Belgium
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Ischemic Heart Disease
Optimal Duration of Clopidogrel in Second-Generation Drug-Eluting Stents
Investigators try to assess the safety of 6-months or 12-months maintenance of dual antiplatelet therapy (DAPT, aspirin + clopidogrel) in patients undergoing percutaneous coronary intervention using the Zotarolimus-eluting…
- Trial name
- OPTIMA-C (NCT03056118)
- Testing
- 6-month dual anti-platelet therapy, 12-month dual anti-platelet therapy, Zotarolimus eluting stent
- Volunteers
- 1,368 people
- Sponsor
- Gangnam Severance Hospital
Embryo Implantation, Infertility
Clinical Trial of Novel Implantation Promoting Medium (EmbryoGlue) to Improve IVF Success Rates
Hypothesis: a special solution for improving human embryo implantation, when added to the solution during embryo transfer, will improve implantation rates in embryo transfers using previously frozen embryos.
- Trial name
- NCT00588250
- Testing
- EmbryoGlue
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Intraocular Lens
Comparison of the Visual Performance After Implantation of Multifocal Lens
This is a prospective, consecutive, nonrandomized,comparative study. Comparison of the Visual Performance After Implantation of a Trifocal Intraocular Lens and Two Bifocal Intraocular Lenses
- Trial name
- NCT03586271
- Testing
- trifocal lens, bifocal lens 1, bifocal lens 2
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Aier School of Ophthalmology, Central South University
Acute on Chronic Systolic Congestive Heart Failure, Cardiorenal Syndrome
Feasibility of the SCD in Cardiorenal Syndrome Patients Awaiting LVAD
Cardiovascular disease is the leading cause of mortality in the US, accounting for 45% of all deaths. Chronic Heart Failure (CHF) is now understood to be a multi-system disease process involving not only the cardiovascular system…
- Trial name
- NEUTRALIZE-CRS (NCT03836482)
- Testing
- Selective Cytopheretic Device
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- SeaStar Medical
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