Clinical trials: EMBRYO IMPLANTATION
Breast Implant Revision, Congenital Breast Defect Correction
Scaffold-guided Breast Surgery
The clinical trial is testing the use of a novel method to grow new tissue within the breast injecting fat tissue harvested from patient's own fat deposits.
- Trial name
- NCT05437757
- Testing
- Surgical implantation of the PCL Breast scaffold with autologous fat grafting
- Where
- Australia
- Volunteers
- 19 people
- Sponsor
- BellaSeno Pty Ltd
Chronic Spinal Cord Injury
RESTORES Trial: RESToration Of Rehabilitative Function With Epidural Spinal Stimulation
Spinal Cord Injury (SCI), being a devastating diagnosis, has little to no recovery which leads to a long-standing of debilitating impairment for affected patients.
- Trial name
- RS-01 (NCT05644171)
- Testing
- RESToration Of Rehabilitative function with Epidural spinal Stimulation
- Where
- Singapore
- Volunteers
- 18 people
- Sponsor
- National Neuroscience Institute
Cataracts
A Clinical Outcome Study of Two Multifocal Intraocular Lenses (IOL) in Cataract Patients
The purpose of this study is to compare AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL in both eyes (bilateral implantation) to AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL in the dominant eye with AcrySof® IQ ReSTOR® +3.0 D Multifocal…
- Trial name
- NCT01684007
- Testing
- AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL Model SN6AD2 [SV25T0], AcrySof® IQ ReSTOR® +3.0 D Multifocal IOL Model SN6AD1
- Volunteers
- 112 people
- Sponsor
- Alcon Research
Parkinson Disease, Movement Disorders
Long-Term Follow-up Safety After DDS Implantation With/Without CDNF Infusions
This study is a follow up to the HP-CD-CL-2002 clinical study. It evaluates the long-term safety in patients with Parkinson's disease after implantation of an investigational drug delivery system (DDS) with or without infusions…
- Conditions
- Parkinson Disease, Movement Disorders, Neuro-Degenerative Disease, Nervous System Diseases
- Trial name
- NCT04228653
- Testing
- Renishaw Drug Delivery System
- Where
- 3 sites in Finland, Sweden
- Volunteers
- 15 people
- Sponsor
- Renishaw
Malignant Tumors
Clinical Study of Pretreatment PET/CT Parameters for Predicting the Efficacy of 125I Seed Implantation in the Treatment of Malignant Tumors
This study aimed to determine if pre-treatment 18F-FDG PET/CT metabolic parameters could predict the effectiveness of 125I seed implantation for malignant tumors.
- Trial name
- NCT07208487
- Where
- China
- Volunteers
- 41 people
- Sponsor
- Jiangxi Provincial Cancer Hospital
Cardiomyopathy, Heart Failure
Evaluating Myocardial Injury for Defibrillation Threshold Testing Methods for ICD Implantation
The objective of this study is to evaluate myocardial injury, if any, as quantified by cardiac markers (Troponin-T) in defibrillation threshold (DFT) testing during implantation of implantable cardioverter defibrillators (ICDs)…
- Conditions
- Cardiomyopathy, Heart Failure, Cardiac Arrhythmia
- Trial name
- ULV (NCT02111993)
- Testing
- Standard Defibrillation Testing, Upper Limit of Vulnerability Testing
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, San Diego
Parkinson Disease
Embryonic Dopamine Cell Implants for Parkinson's Disease
The purpose of this trial is to determine if patients who received embryonic dopamine cell implant surgery showed significantly greater improvement in their Parkinson's disease than a control group undergoing the placebo…
- Trial name
- NCT00038116
- Testing
- embryonic dopamine cell implant surgery
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- University of Colorado, Denver
Asymmetric Hearing Loss, Single-sided Deafness
Cochlear Implantation in Children With Asymmetric Hearing Loss or Single-Sided Deafness Clinical Trial
This is a two-phase study that compares performance growth pre-implant with current hearing aid (HA) technology versus post-implant with a cochlear implant (CI) in children with either asymmetric hearing loss (AHL) or…
- Conditions
- Asymmetric Hearing Loss, Single-sided Deafness, Unilateral Deafness
- Trial name
- NCT04793412
- Testing
- Cochlear Implant
- Where
- 5 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Chronic Leg Ulcer, Sickle Cell Disease
Autologous Bone Marrow Stem Cells for Chronic Leg Ulcer Treatment in Sickle Cell Disease
The purpose of this study is to evaluate the safety and efficacy of autologous bone marrow stem cell implantation for the treatment of leg ulcer in adult patients with sickle cell disease.
- Trial name
- NCT02619734
- Testing
- Infusion of Autologous Bone Marrow Mononuclear Cells
- Volunteers
- 40 people
- Sponsor
- Federal University of Bahia
Leadless Pacemaker, Same-day Discharge
Vascular Access for Minimally-invasive Leadless Pacemaker Implantation Through the Right Jugular routE
Leadless pacemakers (LP) are associated with a lower risk of revision compared with transvenous pacemakers. However, LPs implantation is associated with a 0.6% risk of complication at the femoral vein puncture site (e.g.
- Trial name
- VAMPIRE (NCT06455566)
- Testing
- Leadless pacemaker implantation through right internal jugular vein
- Where
- 13 sites in France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Caen
Premature Ovarian Insufficiency, Intrauterine Adhesion
Application of Platelet-rich Plasma (PRP) in Reproductive Medicine
Female fertility is affected by many factors, such as ovarian function, fallopian tube patency, uterine environment, and mental state, among which the ovaries and endometrium are more important.
- Conditions
- Premature Ovarian Insufficiency, Intrauterine Adhesion, Poor Ovarian Response, Repeated Implantation Failure
- Trial name
- NCT06645379
- Testing
- Platelet-Rich Plasma (PRP) Injections
- Where
- China
- Volunteers
- 300 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Hearing Loss
Percutaneous Cochlear Implantation: Implementation of Technique
The investigators are studying a new way of doing cochlear implant surgery called "Percutaneous Cochlear Implantation". In this surgery, instead of doing a mastoidectomy where about 30ml of bone is removed, the investigators use…
- Trial name
- PCI-I (NCT01460823)
- Testing
- Percutaneous Cochlear Implantation using image guided surgical techniques
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Vanderbilt University
Mechanical Complication of Cardiac Pacemaker
Comparison of Axillary Vein Puncture With Subclavian Vein Puncture in Pacemaker Implantation
The intrathoracic subclavian venous technique for pacemaker implantation may be associated with serious complications. Axillary vein puncture tends to reduce lead implantation complications such as pneumothorax and lead crush…
- Trial name
- NCT02358551
- Testing
- Placement of electrode lead through axillary vein puncture, Placement of electrode lead through subclavian vein puncture
- Where
- China
- Volunteers
- 220 people
- Sponsor
- China-Japan Friendship Hospital
Infertility, In Vitro Fertilization
Injection of Day 2 Embryo Culture Supernatant Into the Uterine Cavity Didn't Improve Implantation and Pregnancy Rates
Forty-five infertile women undergoing in vitro fertilization treatment were managed by uterine cavity injection of day 2 embryo culture supernatant before day 3 embryo transfer.
- Trial name
- NCT00730496
- Testing
- uterine cavity injection of day 2 embryo culture supernatant
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Shen-Zhen City Maternity and Child Healthcare Hospital
Cataract, Presbyopia Correction
Photopic and Mesopic Multifocal IOL Performance
Modern cataract surgery has become a refractive procedure. Both, multifocal lens implantation and pseudophakic monovision with monofocal IOLs are effective means to address presbyopia correction after cataract surgery.
- Trial name
- MIOLRead (NCT06978556)
- Testing
- No intervention is subject of the study. Only standard pre- and postoperative data will be evaluated.
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- IROC AG
Effect of PGD on Implantation Rates in IVF Cycles
Study of the Efficacy of 24 Chromosome Preimplantation Genetic Diagnosis (PGD)
The purpose of this study is to determine if 24 chromosome preimplantation genetic diagnosis (PGD) increases implantation and delivery rates in couples attempting to conceive through in vitro fertilization (IVF).
- Trial name
- NCT01219283
- Where
- 3 sites in United States
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- Reproductive Medicine Associates of New Jersey
Preimplantation Gentic Screening (PGS), In Vitro Fertilization (IVF)
Impact of Parental Support on Pregnancy Outcomes (IPSO) Trial- Day 3 Preimplantation Genetic Screening (PGS) With Day 5 Fresh Transfer
Natera is recruiting patients for a research study evaluating pregnancy and implantation rates in women undergoing In Vitro Fertilization (IVF) and Preimplantation Genetic Screening (PGS).
- Conditions
- Preimplantation Gentic Screening (PGS), In Vitro Fertilization (IVF), Preimplantation Genetic Diagnosis (PGD)
- Trial name
- IPSO (NCT01194531)
- Testing
- 24 Chromosome Aneuploidy Screening with Parental Support
- Where
- 9 sites in United States
- Volunteers
- 59 people
- Sponsor
- Natera, Inc.
Necrosis
Treatment of Osteonecrosis of the Femoral Head by Bone Marrow Transplantation
Aseptic non traumatic osteonecrosis (ON) is a painful disorder of the hip which often leads, in its final stage, to femoral head collapse and subsequent total hip replacement.
- Trial name
- NCT00821470
- Testing
- core decompression, Bone marrow implantation into the necrotic lesion
- Where
- Belgium
- Volunteers
- 21 people
- Sponsor
- Erasme University Hospital
Sterility
Embryo Implantation After Induced Endometrial Injury
Some studies have revealed that an induced endometrial injury could improve embryo human implantation in patients with implantation failure.
- Trial name
- NCT01955356
- Testing
- Scratching
- Where
- Spain
- Volunteers
- 600 people
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Percutaneous Coronary Intervention (PCI), Atrial Fibrillation (AF)
Monotherapy With P2Y12 Inhibitors in Patients With Atrial fIbrillation Undergoing Supraflex Stent Implantation
Patients with atrial fibrillation undergoing percutaneous coronary intervention with stent implantation require treatment with different antithrombotic drugs.
- Conditions
- Percutaneous Coronary Intervention (PCI), Atrial Fibrillation (AF), Oral Anticoagulation, P2Y12 Inhibitor
- Trial name
- MATRIX-2 (NCT05955365)
- Testing
- P2Y12 inhibitor, Aspirin, DOAC
- Where
- 15 sites in Belgium, France and 7 more
- Volunteers
- 3,010 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
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