Clinical trials: EMBRYO IMPLANTATION
Pancreatic Adenocarcinoma Non-resectable, Pancreatic Adenocarcinoma Metastatic
Open-Label Phase 2 Efficacy Trial of Cancer Macrobeads in Patients With Treatment-Resistant Pancreatic/Colorectal Cancer
This is a clinical research study of an investigational (FDA BB-IND 10091) treatment for patients with pancreatic cancer (all stages) and advanced colorectal cancer that no longer responds to standard therapies.
- Conditions
- Pancreatic Adenocarcinoma Non-resectable, Pancreatic Adenocarcinoma Metastatic, Colorectal Cancer Metastatic
- Trial name
- Macrobead (NCT01053013)
- Testing
- RENCA macrobeads
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- The Rogosin Institute
Bioprosthetic Valve Failure, Prosthetic Heart Valve Dysfunction
REVIVE-FR Registry
This registry aims to investigate treatment options for patients whose previously implanted biological aortic heart valve no longer functions properly.
- Conditions
- Bioprosthetic Valve Failure, Prosthetic Heart Valve Dysfunction, Structural Valve Deterioration, Prosthetic Heart Valve Thrombosis
- Trial name
- NCT07885761
- Testing
- TAVI-in-SAVR (Valve-in-Valve), THV-in-THV (Redo-TAVI), Surgical Explantation of a Failed Transcatheter Heart Valve
- Volunteers
- 200 people
- Sponsor
- Institut für Pharmakologie und Präventive Medizin
Cochlear Implantation
Follow-up of Cochlear Implanted Children at 3 Years : Comparison of Electrophysiological and Speech-language Results
The objective of the study is to compare the responses recorded with automated cortical auditory evoked potentials, of children who had one or two cochlear implants for 3 years, and the results of the speech therapy assessment.
- Trial name
- ImplantHear3 (NCT04192968)
- Testing
- Cortical auditory evoked potentials, Additional exams
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Coronary Artery Stenosis
Optimal Predilatation Technique for BVS Implantation
The purpose of this study is to determine the optimal way of predilatation for BVS implantation.
- Trial name
- OPTI-BVS (NCT02946320)
- Testing
- Predilatation with non-compliant balloon, Predilatation with scoring balloon (Scoroflex), Predilatation with cutting balloon (Flextome)
- Volunteers
- 45 people
- Sponsor
- Cardiology Center Agel
IOL, Cataract
The Clinical Importance of Angle Alpha by Multifocal Intraocular Lenses.
Purpose: to evaluate the effect of visual axis positioning on the optical performance of the Tecnis MIOL and the Diff-aA MIOL.
- Trial name
- NCT04274088
- Testing
- Cataract surgery
- Volunteers
- 65 people
- Sponsor
- Hospital Hietzing
Serratus Anterior Plane Block, Transversus Thoracis Plane Block
Serratus Anterior Plane Block Combined With Transversus Thoracic Muscle Plane Block Versus Conventional Local Anesthetic Infiltration for SICD Implantation: A Randomized Controlled Trial
This is a prospective randomized study. The aim is to investigate the efficacy of a combined SAPB with TTPB for perioperative pain control compared to the standard local anesthetic infiltration technique in adult patients…
- Conditions
- Serratus Anterior Plane Block, Transversus Thoracis Plane Block, Subcutaneous ICD
- Trial name
- NCT05092490
- Testing
- Combined serratus anterior plane block and transversus thoracis plane block, Standard local infiltration technique
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- New York Presbyterian Brooklyn Methodist Hospital
Amputation of Upper Limb
A Multicenter, Multinational, Cohort Long-term Post-market Clinical Follow-up (PMCF) of the Safety and Efficacy of the Osseoanchored Prostheses for the Rehabilitation of Amputees (OPRA) Implant System When Used for Transhumeral Implantation in Amputee Patients
This non-interventional clinical investigation is initiated for the purpose of long-term Post-Market Clinical Follow-up (PMCF) and the follow-up time of patients is expected to span from 6 months to >20 years in function.
- Trial name
- ReTHro (NCT06753110)
- Testing
- OPRA transhumeral
- Where
- 6 sites in Australia, Austria and 3 more
- Volunteers
- 70 people
- Sponsor
- Integrum
Repeated Implantation Failure
Intrauterine Injection of Human Chorionic Gonadotrophin and Pregnancy Rate in ICSI
Despite recent advances in clinical and laboratory techniques of Assisted Reproductive Technology (ART), the pregnancy rate remains around 30% per cycle.
- Trial name
- NCT03445910
- Testing
- Human chorionic gonadotropin
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Osteoarthritis
Total Knee Arthroplasty With Personalized Implantation: Computer Navigation-Assisted Surgery Versus Robotic-Assisted Surgery
Title: Personalized Total Knee Arthroplasty: Computer-Assisted Navigation vs. Robotic Assistance (CAN-ARD). Summary: Knee osteoarthritis is frequently treated with Total Knee Arthroplasty (TKA).
- Trial name
- CAN-ARD (NCT07574762)
- Testing
- Robotic-Arm Assisted Surgery (RA), Computer-Assisted Navigation (CAN)
- Where
- France
- Volunteers
- 140 people
- Sponsor
- Groupe Hospitalier Diaconesses Croix Saint-Simon
Infertility
3D Ultrasound Measurement of Junctional Zone Thickness and Its Relation to Implantation Success
100 patients aged 21-40 years old, diagnosed as primary or secondary infertility . These patients are then assigned to receive fertility treatment (ovulation induction, ICSI, intrauterine insemination and IVF).
- Trial name
- NCT02362061
- Testing
- 3D ultrasound
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
Glaucoma
Results of Different Location of Ahmed Glaucoma Valve Implantation in Refractory Glaucoma, Superior Versus Inferior
Purpose:To compare the efficacy and safety of Ahmed Glaucoma Valve (AGV) implantation in the superior versus inferior quadrants.
- Trial name
- NCT00628173
- Testing
- AGV implantation
- Volunteers
- 106 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Mechanical Complication of Cardiac Pacemaker
Comparison of Axillary Vein Puncture With Subclavian Vein Puncture in Pacemaker Implantation
The intrathoracic subclavian venous technique for pacemaker implantation may be associated with serious complications. Axillary vein puncture tends to reduce lead implantation complications such as pneumothorax and lead crush…
- Trial name
- NCT02358551
- Testing
- Placement of electrode lead through axillary vein puncture, Placement of electrode lead through subclavian vein puncture
- Where
- China
- Volunteers
- 220 people
- Sponsor
- China-Japan Friendship Hospital
Drug-eluting Stent (DES)
Aspirin Mono Therapy 12-months After Drug-eluting Stents Implantation
The purpose of this study is to determine whether high dose statin therapy in patients with aspirin mono antiplatelet therapy who had received drug-eluting stent (DES) previously and were free of the adverse cardiac events during…
- Trial name
- statin (NCT01557075)
- Testing
- Atorvastatin (High dose statin treatment), Pravastatin (High dose statin treatment)
- Where
- South Korea
- Volunteers
- 2,000 people
- Sponsor
- Yonsei University
Atrial Fibrillation
Impact of Implantation of an LAA Occluder on ANP and BNP Level and Quality of Life
Closure of the LAA by several devices is a alternative therapy to oral anticoagulation in patients with Atrail fibrillation. Nothing is known about the acute influence of a device closure of the LAA on the secretion of ANB nad…
- Trial name
- NCT03085667
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- University of Leipzig
Intracranial Arteriosclerosis, Intracranial Artery Stenosis
Comparison Three vs Six Months of Dual Anti-platelet Therapy After Sirolimus-eluting Stent Implantation
This study is a prospective, multicenter, open-label, randomized controlled clinical trial, aims to assess the clinical non-inferiority of 3 months (short-term) vs 6 months (long-term) of Dual Anti-Platelet Therapy (DAPT) in…
- Conditions
- Intracranial Arteriosclerosis, Intracranial Artery Stenosis, Drug-Eluting Stents
- Trial name
- NCT06857045
- Testing
- NOVA intracranial sirolimus-eluting stent system
- Where
- China
- Sponsor
- Sino Medical Sciences Technology Inc.
Angina Pectoris
Myocardial Ischemia After Coronary Sinus Reduction Stent Implantation
Chronic angina pectoris refractory to medical and revascularization therapies is a disabling medical condition and a major public health problem. Patients with refractory angina have limited treatment options.
- Trial name
- MICS-Reduce (NCT06033495)
- Testing
- Coronary sinus reduction stent
- Volunteers
- 15 people
- Sponsor
- Oslo University Hospital
Coronary Heart Disease
Recovery of Left Ventricular Function in Chronic Total Occluded Coronary Arteries
The study is a randomised comparison of recanalisation of chronic occluded coronary arteries with implantation of Sirolimus eluting stents and medical therapy.
- Trial name
- REVASC (NCT01924962)
- Testing
- revascularisation
- Where
- Germany
- Volunteers
- 205 people
- Sponsor
- University Heart Center Freiburg - Bad Krozingen
Hearing Loss, Hearing Loss, Sensorineural
Cochlear Implant Recipients: Comprehensive Longitudinal Evaluation
This study aims to assess hearing and speech perception, as well as quality of life, in deaf patients of all ages before and after cochlear implantation, and to explore differences across age groups and treatment subtypes…
- Conditions
- Hearing Loss, Hearing Loss, Sensorineural, Deafness, Cochlear Implantation
- Trial name
- CIRCLE (NCT07380269)
- Testing
- Cochlear Implantation
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Recurrent Implantation Failure
PRP in Recurrent Implantation Failure
The endometrial function and endometrial receptivity have been accepted to be major limiting factors in the establishment of pregnancy.
- Trial name
- NCT04085783
- Testing
- PRP
- Where
- Bahrain
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Dr. Kamal Rageh
Epilepsy
Transcranial Direct Current Stimulation (tDCS) As A Tool For Prospective Responder Identification Before Vagus Nerve Stimulation (VNS) Implantation
The aim of the study is to establish tDCS as a prognostic tool to predict VNS therapy outcome among patients with pharmacoresistant epilepsy.
- Trial name
- NCT00625222
- Testing
- transcranial direct current stimulation
- Where
- Germany
- Volunteers
- 70 people
- Sponsor
- University of Luebeck
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