Clinical trials: EMBRYO IMPLANTATION
Sterility
Embryo Implantation After Induced Endometrial Injury
Some studies have revealed that an induced endometrial injury could improve embryo human implantation in patients with implantation failure.
- Trial name
- NCT01955356
- Testing
- Scratching
- Where
- Spain
- Volunteers
- 600 people
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Patellofemoral Osteoarthritis
Implantation of Engineered Cartilage Grafts for Treatment of Patellofemoral Osteoarthritis Versus Surgical Comparators.
ENCANTO is a randomized, controlled, multi-center phase II clinical trial for the treatment of patellofemoral osteoarthritis (PFOA) with an Advanced Therapy Medicinal Product (ATMP), nasal chondrocyte-based tissue engineered…
- Trial name
- ENCANTO (NCT06576583)
- Testing
- Engineered cartilage graft (N-TEC), Autologous Matrix Induced Chondrogenesis (AMIC), Patellofemoral Arthroplasty (PFA)
- Where
- 11 sites in Austria, Croatia and 6 more
- Volunteers
- 150 people
- Sponsor
- University Hospital, Basel, Switzerland
Foramen Ovale, Patent, Nickel Sensitivity
Investigation of Nickel Sensitization After Percutaneous Implantation of Patent Foramen Ovale Occluder
Percutaneous PFO closure has been established as a first-line therapy for preventing recurrent strokes in selected patients. The devices used for the specific purpose contain and release nickel, which is considered as the most…
- Conditions
- Foramen Ovale, Patent, Nickel Sensitivity, Dermatitis Contact Irritant, Metal Allergy
- Trial name
- INSPIRE (NCT04713683)
- Testing
- Percutaneous Patent Foramen Ovale Closure
- Where
- Greece
- Volunteers
- 96 people
- Sponsor
- National and Kapodistrian University of Athens
Refractive Errors
Measurement of Refractive SE Following Implantation of LS313 MF30 IOL
This Study determines the most precise method for measuring post-operative refraction following implantation of the asymmetric multifocal LS-313 MF30 comparing the results of Refraction of the different Autorefractor Keratometers…
- Trial name
- NCT03292614
- Testing
- Measurements of the postoperative refraction
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- Dietrich-Bonhoeffer-Klinikum
Alveolar Bone Resorption
Socket Shield Technique With or Without Flap Elevation
It is aimed to compare the bone changes and the amount of marginal bone loss after prosthetic loading around the immediately placed implants using the Socket Shield Technique with or without flap elevation.
- Trial name
- NCT05492838
- Testing
- Immediate implantation with the Socket Shield Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Aortic Valve Stenosis
REPRISE IV: LOTUS Edge Valve System in Intermediate Surgical Risk Subjects
REPRISE IV: REpositionable Percutaneous Replacement of Stenotic Aortic Valve through Implantation of LOTUS Edge Valve System in IntermediatE Surgical Risk Subjects
- Trial name
- REPRISE IV (NCT03618095)
- Testing
- LOTUS Edge Valve System
- Where
- 50 sites in United States, Australia
- Volunteers
- 382 people
- Sponsor
- Boston Scientific Corporation
Complex Congenital Heart Defect, Dysfunctional RVOT Conduit
COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve Dysfunction
This study will demonstrate the safety and effectiveness of the Edwards Lifesciences SAPIEN 3/SAPIEN 3 Ultra RESILIA Transcatheter Heart Valve (THV) Systems in subjects with a dysfunctional right ventricular outflow tract (RVOT)…
- Conditions
- Complex Congenital Heart Defect, Dysfunctional RVOT Conduit, Pulmonary Valve Insufficiency, Pulmonary Valve Degeneration
- Trial name
- NCT02744677
- Testing
- SAPIEN 3/SAPIEN 3 Ultra RESILIA THV, SAPIEN 3 THV, SAPIEN 3 Ultra RESILIA THV
- Where
- 27 sites in United States
- Volunteers
- 108 people
- Sponsor
- Edwards Lifesciences
Primary Open-angle Glaucoma
SIGHT Study: Cost-effectiveness of InnFocus Microshunt Implantation vs. Trabeculectomy.
The standard surgical treatment for glaucoma is trabeculectomy. The PRESERFLO™ (formerly InnFocus) Microshunt (IMS) is a new, minimally invasive drainage device which has been suggested to result in similar IOP lowering, but with…
- Trial name
- SIGHT (NCT03931564)
- Testing
- PRESERFLO Microshunt implantation, Trabeculectomy
- Where
- Netherlands
- Volunteers
- 124 people
- Sponsor
- Maastricht University Medical Center
First Time Dual Chamber Pacemaker Implantation
Valsartan to Prevent Left Ventricle Remodeling in Pacemaker Patients
Dual chamber pacing is known to induce left ventricle remodeling and may eventually lead to heart failure. The investigators aim to test hypothesis that valsartan started immediately after dual chamber pacemaker implantation will…
- Trial name
- NCT01805804
- Where
- Poland
- Volunteers
- 88 people
- Sponsor
- Medical University of Silesia
Aortic Valve Disease, Myocardial Infarction
Aspirin Versus Aspirin + ClopidogRel Following Transcatheter Aortic Valve Implantation: the ARTE Trial
The purpose of this study is to compare aspirin + clopidogrel with aspirin alone as antithrombotic treatment following transcatheter aortic valve implantation (TAVI) for the prevention of major ischemic events [myocardial…
- Conditions
- Aortic Valve Disease, Myocardial Infarction, Stroke
- Trial name
- ARTE (NCT01559298)
- Testing
- Aspirin (80 mg/d) + clopidogrel (75 mg/d), Aspirin
- Where
- 2 sites in Canada
- Volunteers
- 178 people
- Sponsor
- Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec
Cochlear Implants, Sensory-Neural Hearing Loss
Balance in Children With Cochlear Implants
Cochlear implantation is performed in children with sensorineural hearing loss to restore hearing. Fifty percent of children with sensory neural hearing loss, who are candidates for cochlear implant, have vestibular (inner ear)…
- Conditions
- Cochlear Implants, Sensory-Neural Hearing Loss, Balance Disorder
- Trial name
- NCT03620500
- Testing
- Gross motor and developmental balance testing
- Where
- United States
- Sponsor
- Vanderbilt University Medical Center
Cartilage Repair
Implantation of Cartilage Mini-grafts Made From Donor Cells to Treat Chondral Lesions of the Knee
The purpose of this study is to investigate the safety and feasibility of implanting allogeneic cartilage mini-grafts (or allogenic Cartibeads) into cartilage defects in the knee.
- Trial name
- NCT06897111
- Testing
- Implantation of allogeneic cartilage mini-grafts (Allogeneic Cartibeads)
- Where
- 4 sites in Switzerland
- Volunteers
- 10 people
- Sponsor
- Vanarix SA
Aging of Breast Implants
Understanding the Phenomena of Aging and Rupture of Breast Implants
Breast implants, like all implantable medical devices, are subject to wear and tear as they age in the body. In addition to this wear and tear, they are subject to external trauma, whether accidental during daily life, during…
- Trial name
- CRIMA (NCT05527132)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Strasbourg, France
TAVI(Transcatheter Aortic Valve Implantation)
SAIRO - Feasibility and Safety of the Tele-operated TAVIPILOT Robot Guided by TAVIPILOT Software
The TAVIPILOT robotic platform, developed by Caranx Medical is an advanced intraoperative robotic assistance system designed to enhance the precision of transcatheter aortic valve positioning during TAVR.
- Trial name
- SAIRO (NCT07664163)
- Testing
- TAVR procedure with TAVIPILOT Software and tele-operated robot by Caranx Medical enhancing the precision of transcatheter aortic valve positioning during TAVR.
- Where
- 2 sites in Australia
- Volunteers
- 10 people
- Sponsor
- Caranx Medical
Placenta Implantation Site
Relation of Implantation Site to Placental Site
Trans vaginal ultrasound with a partially full bladder will be done at gestational age earlier than 10 weeks to assess the site of intrauterine gestational sac to the endometrial cavity and the distance between the implantation…
- Trial name
- NCT02765984
- Testing
- Transvaginal ultrasound
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Cairo University
Infertility, Subfertility
Effect of hCG on Receptivity of the Human Endometrium
Worldwide, 1 in 12 couples experience difficulty in getting pregnant and seek the help of assisted reproductive technologies (ART) such as in vitro fertilization (IVF-egg is fertilized by sperm outside the body), ovarian…
- Trial name
- NCT01786252
- Testing
- human chorionic gonadotropin (hCG)
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Bladder Dysfunction
The Utility of Shanfield Implantation Technique During Creation of Mitrofanoff Procedure in Pediatric Age Group
Management of bladder dysfunction was revolutionized by the introduction of intermittent catheterization by Lapides. Later, Mitrofanoff described a trans-appendicular continent cystostomy, launching a new concept whereby the…
- Trial name
- NCT06472193
- Testing
- Shanfield implantation technique in Mitroffanof procedure
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Sohag University
End-stage Heart Failure
Long-Term Survival After LVAD Implantation in End-Stage Heart Failure
This is a prospective, observational, multi-center cohort study designed to evaluate long-term survival and clinical outcomes in patients with end-stage heart failure undergoing left ventricular assist device (LVAD) implantation.
- Trial name
- NCT07382284
- Testing
- Left Ventricular Assist Device (LVAD) implantation
- Where
- China
- Volunteers
- 300 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Abdominal Aortic Aneurysm
Prophylactic Mesh Implantation After Abdominal Aortic Aneurysm Repair
AIDA Study is a prospective, multicentre, randomized, controlled clinical investigation with patients undergoing median laparotomy for Abdominal Aortic Aneurysm (AAA) repair.
- Trial name
- NCT01353443
- Testing
- Optilene® Mesh Elastic
- Where
- 9 sites in Germany
- Volunteers
- 282 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Infertility, Endometrial Diseases
Endometrial Injury In Recurrent Implantation Failure
The aim of this study is to investigate that the efficacy of the endometrial injury before IVF in recurrent implantation failure patients.
- Trial name
- NCT03748238
- Testing
- Endometrial Injury with Hysteroscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 230 people
- Sponsor
- Gurgan Clinic
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