Clinical trials: EMERGENCY MEDICINE
Acute Myocardial Infarction
Bystander Helping Behaviour for Myocardial Infarction Following First Aid Training
The objective of this study is to measure the effect of an innovative training programme on the help seeking behaviour and helping rates of bystanders in medical emergencies.
- Trial name
- NCT00954161
- Testing
- Helping behaviour curriculum, First aid only curriculum
- Where
- Belgium
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Overdose, Drug, Drug Use
ASSIST: A Surveillance Study of Illicit Substance Toxicity
There is a drug-related death crisis in Scotland. This study aims to collaborate with Public Health Scotland in order to assess the feasibility of introducing a surveillance system to the Emergency Department to highlight illicit…
- Conditions
- Overdose, Drug, Drug Use, Drug Abuse, Drug Toxicity
- Trial name
- ASSIST (NCT05329142)
- Testing
- Surplus sample toxicology analysis
- Where
- United Kingdom
- Volunteers
- 1,000 people
- Sponsor
- NHS Greater Glasgow and Clyde
Renal Colic
Oral NSAI Versus Acetaminophen or Placebo as a Discharge Treatment of Non Complicated Renal Colics
Treatment with NSAI in renal colics has not been well investigated and there is no clear recommendations regarding this subject.
- Trial name
- NAP-RC (NCT05722782)
- Testing
- Piroxicam, Acetaminophen
- Where
- Tunisia
- Volunteers
- 500 people
- Sponsor
- University of Monastir
Asthmatic Patients, MDI
Assessment of Emergency Spacers Versus Traditional Spacers for Delivery of Aerosolized Drugs
The goal of this clinical trial is to evaluate the performance, feasibility, and safety of emergency spacers compared to traditional spacers for the delivery of aerosolized drugs using pMDI.
- Conditions
- Asthmatic Patients, MDI, Aerosol Generating Procedure
- Trial name
- NCT06816342
- Testing
- Ventoline® Evohaler® 100 µg/inhalation pMDI alone, Ventoline® Evohaler® 100 µg/inhalation pMDI connected to Able spacer, Ventoline® Evohaler® 100 µg/inhalation pMDI connectec to Tips-Haler spacer
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Beni-Suef University
Supraventricular Tachycardia (SVT)
PERceptions of Diltiazem Versus ADEnosine for Treatment of Supraventricular Tachycardia in the Emergency Department
Supraventricular tachycardia (SVT) is a dysrhythmia characterized rapid heart rate, typically with rapid onset. SVT accounts for over 50,000 emergency department visits per year.
- Trial name
- PERVADE-ED (NCT07086560)
- Testing
- IV adenosine, IV diltiazem
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Iowa
Opioid-Use Disorder (OUD)
SafetyNet Program for Opioid Use Disorder (OUD)
The principal aim of this study is to determine whether a novel biopsychosocial intervention following opioid overdose (OD) affects 1) the frequency of secondary opioid OD events and 2) the proportion of individuals who remain…
- Trial name
- NCT04253782
- Testing
- Team Intervention
- Where
- 2 sites in United States
- Volunteers
- 81 people
- Sponsor
- Yale University
Sepsis, Shock
Fluid Management and Individualized Resuscitation in Sepsis
The goal of this clinical trial is to find out if a personalized treatment approach can improve care for people with sepsis in the emergency department (ED).
- Conditions
- Sepsis, Shock, Personalized Medicine, Emergency Medicine
- Trial name
- FLUIDS (NCT07009665)
- Testing
- Personalized SV-guided resuscitation, Standard Care Resuscitation
- Where
- Netherlands
- Volunteers
- 188 people
- Sponsor
- University Medical Center Groningen
Sepsis
Early PREdiction of Severe Sepsis I (ExPRES-Sepsis I) Study
Between 6 and 16% of patients presenting to hospital emergency departments have infections, with half of these having signs of systemic inflammation (known as 'sepsis').
- Trial name
- ExPRES (NCT02188992)
- Where
- 3 sites in United Kingdom
- Volunteers
- 401 people
- Sponsor
- University of Edinburgh
Geriatric, Elderly
A Descriptive Multicenter Investigation of Geriatrics Hotlines : A French Study
In France, for general practitioners, the Emergency Hospitality Services (UAS) are the fastest and usual way to respond to the complexity of managing elderly polypathological patients.
- Trial name
- NCT03959475
- Where
- France
- Volunteers
- 2,000 people
- Sponsor
- Support and Education Technic Centre
Educational Problems
Mobile Education for Emergency Ultrasound
The investigators aim to investigate the feasibility of using mobile application platform for sonographic education. Junior physicians at the National Taiwan University Hospital will be enrolled in this study.
- Trial name
- NCT03738033
- Testing
- educational platform
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- National Taiwan University Hospital
Emergency Medicine, Well-Being, Psychological
ED Adaptive Staffing Study
Emergency Departments (EDs) across Ontario are being inundated with unprecedented high patient volumes and a staffing shortage that directly impacts patient care and flow.
- Trial name
- FAST-ED (NCT05937763)
- Testing
- Staffing model
- Where
- Canada
- Volunteers
- 5,917 people
- Sponsor
- Oak Valley Health
Pain
An Efficacy and Safety of Proprietary Formulations of Oral Ketamine + Aspirin in Treatment of Acute Headache
Headaches affect over 50% of patients annually, with close to 4% of ED visits for headache. Most headaches managed in the ED are benign, with 90% of these headaches classified as tension, migraine, or cluster.
- Trial name
- NCT04860713
- Testing
- aspirin and ketamine, Nurtec (Rimegepant)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Antonios Likourezos
Craniocerebral Trauma, Brain Injuries, Traumatic
Socio-Cultural Level, Health Literacy, and Parental CT Demand in Paediatric Minor Head Trauma
Minor head trauma is one of the most frequent reasons for paediatric emergency department visits worldwide. The PECARN (Paediatric Emergency Care Applied Research Network) clinical decision rule stratifies children with minor…
- Conditions
- Craniocerebral Trauma, Brain Injuries, Traumatic, Head Injuries, Closed
- Trial name
- NCT07655310
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Well-being at Work, Burnout
Emergency Medicine Practitioners Overall Well-being Enhancement With Ambient AI Scribes
The primary objective of the study is to investigate the impact of an ambient AI scribe on clinicians' wellness and well-being outcomes; additionally, the investigators will also explore how the use of the ambient AI scribe will…
- Trial name
- EMPOWER (NCT07742761)
- Testing
- Ambient AI Scribe
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Washington University School of Medicine
Pediatric ALL, Acute Disease
Improving Nighttime Access to Care and Treatment; Part 2- Ghana
Globally, leading causes of death among children one month to 5 years old are pneumonia, diarrheal disease and malaria which are treatable early in the disease-course with low-cost medications.
- Trial name
- INACT2-G (NCT05506683)
- Testing
- MotoMeds pediatric telemedicine and medication delivery service (TMDS)
- Where
- Ghana
- Volunteers
- 1,239 people
- Sponsor
- University of Florida
Mechanical Ventilation, Acute Respiratory Distress Syndrome
Ventilation's Parameters Applied in Emergency Medicine. A Prospective Observational Study
To prospectively assess the mechanical ventilation management when its provided by Emergency Physicians in French Hospital, and to assess complications and outcome of these patients.
- Conditions
- Mechanical Ventilation, Acute Respiratory Distress Syndrome, Protective Ventilation, Survival
- Trial name
- PARAVENT (NCT03351920)
- Testing
- mechanical ventilation
- Where
- 7 sites in France
- Volunteers
- 229 people
- Sponsor
- Poitiers University Hospital
Difficult Intravenous Access, Midline Catheter
Single Lumen Midline Catheter vs Long Peripheral Intravenous Cather for Difficult Intravenous Access in the ED
Many patients in the emergency department have veins that are difficult to get an intrevenous (IV) catheter into (called "difficult IV access").
- Conditions
- Difficult Intravenous Access, Midline Catheter, Peripheral Intravenous Catheter, Emergency Department Patient
- Trial name
- NCT06668766
- Testing
- 10-cm Single Lumen Mildine, 4.78 cm Long Peripheral Intravenous Catheter
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- Albany Medical College
Alcohol Abuse
Study of an Emergency Department-based Intervention to Reduce Alcohol Misuse in Older Adults
This is a randomized trial to assess the value of an emergency department-based intervention to reduce hazardous alcohol use among older adults.
- Trial name
- NCT02236494
- Testing
- Brief Negotiated Interview, General Health Information
- Where
- United States
- Volunteers
- 222 people
- Sponsor
- University of North Carolina, Chapel Hill
Pediatric ALL, Cardiac Arrest
Effect of IAM With an I-gel® on Ventilation Parameters in Simulated Pediatric OHCA
Pediatric cardiac arrest occurs most in the prehospital setting. Most of them are due to respiratory failure (e.g., trauma, drowning, respiratory distress), where hypoxia leads to cardiac arrest.
- Conditions
- Pediatric ALL, Cardiac Arrest, Cardiopulmonary Arrest, Resuscitation
- Trial name
- NCT05498402
- Testing
- i-gel ® device, bag-valve-mask ventilation
- Where
- 4 sites in Switzerland
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Geneve TEAM Ambulances
Adverse Drug Event
Effectiveness of an ADE-related Hospitalization Risk Prediction Tool for Patients (ADE-RED)
The rationale for this study is to evaluate the effectiveness of a risk prediction tool for patients who are at high risk for ADEs resulting in hospitalization or ED revisit.
- Trial name
- NCT04181775
- Testing
- ADE-RED scoring tool
- Where
- United States
- Volunteers
- 471 people
- Sponsor
- Methodist Health System