Clinical trials: EMERGENCY MEDICINE
Pain, Acute Pain
Optimal Management of Pain in Hospitalized Patients - Opioid Tolerant Populations.
Pain is a symptom that drives hospital admissions, and pain management is required by most patients during their hospital stay. Further, the use of medications such as opioids can lead to upward-spiraling doses, especially among…
- Conditions
- Pain, Acute Pain, Postoperative Pain
- Trial name
- NCT02470728
- Testing
- New Clinical Pathway
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Duke University
Communication Barriers
Video-Interpreting in Prehospital Emergency Medicine - Feasibility Study
50 responsive patients with language barriers will be included in this study. The prehospital emergency physician will start video-interpreting via a tablet.
- Trial name
- NCT06322004
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Medical University of Vienna
Anemia
Phenotyping Acute Non-Severe Anemia in the Emergency Department
Anemia is traditionally diagnosed and managed using circulating hemoglobin concentration ([Hb]). However, [Hb] is influenced by plasma volume and may not accurately reflect the total amount of hemoglobin available for oxygen…
- Trial name
- PHENOEMEMIA (NCT07761104)
- Testing
- Total hemoglobin mass measurement, Focused transthoracic echocardiography, Near-infrared spectroscopy
- Where
- France
- Volunteers
- 59 people
- Sponsor
- Hospices Civils de Lyon
Deep Vein Thrombosis, DVT
DVT Ultrasound in the Emergency Department
Emergency Medicine (EM) Residents routinely conduct bedside ultrasound exams in the Emergency Department (ED) employing the two point compression method.
- Trial name
- NCT02369263
- Where
- United States
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Emergency Medicine Physicians, Nevada
Heart Failure, Pulmonary Disease, Chronic Obstructive
Randomized Clinical Trial of a Pharmaceutical Care Program in Chronic Patients Users of an Emergency Department
The study aims to assess the clinical and economic impact of a pharmaceutical care program initiated in the Emergency Department versus conventional follow-up of patients with decompensated heart failure/COPD.
- Trial name
- NCT02368548
- Testing
- Pharmaceutical Care Program, Standard Care
- Volunteers
- 100 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Headache, Migraine
0.5% Bupivacaine Lower Cervical Intramuscular Injection vs IV Medications for Headache Treatment
Headache is a frequent chief complaint among patients presenting to the Emergency Department (ED), accounting for 2.1 million visits annually in the United States.
- Conditions
- Headache, Migraine, Tension Headache, Occipital Neuralgia
- Trial name
- NCT06937385
- Testing
- 0.5% Bupivacaine HCl, standard IV treatment for headache
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- HCA Florida North Florida Hospital
Medication Adherence
Comparative Study of the Performance of Drug Anamneses in an Emergency Department
After the first medical history by the nurse and the emergency physician, the pharmacist and the pharmacy assistant take a detailed history of the patient's medications separately.
- Trial name
- ProtocoleV4 (NCT05951881)
- Testing
- Emergency Care Unit - medicines
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Grand Hôpital de Charleroi
Aortic Dissection
Aortic Dissection Detection Risk Score Plus D-dimer in Suspected Acute Aortic Dissection
Acute aortic dissection (AD) is a deadly, difficult to diagnose disease presenting with an array of common and unspecific symptoms.
- Trial name
- ADvISED (NCT02086136)
- Where
- 6 sites in Brazil, Germany and 2 more
- Volunteers
- 1,900 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Central Venous Catheterization, Ultrasound
Point of Care Echocardiography Versus Chest Radiography for the Assessment of Central Venous Catheter Placement
A prospective study to compare the use of point of care echocardiography versus routine chest radiography for the assessment of central venous catheter placement.
- Conditions
- Central Venous Catheterization, Ultrasound, Emergency Medicine, Critical Care
- Trial name
- NCT02661607
- Testing
- Point of care echocardiography, Central venous catheter placement, Chest radiography
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University of Göttingen
Pediatric Distal Forearm Fractures
Closed Reduction of Distal Forearm Fractures by Pediatric Emergency Medicine Physicians: A Prospective Study
Distal forearm fractures are amongst the most frequently encountered orthopedic injuries in the pediatric emergency department (ED). Immediate closed manipulation and cast immobilization, is still the mainstay of management.
- Trial name
- NCT01101607
- Testing
- Distal Forearm Fracture Reduction
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- InMotion Orthopaedic Research Center
Acute Kidney Injury, Urinary Tract Obstruction
Point-of-care Ultrasound to Assess Hydronephrosis in Patients With Acute Kidney Injury in the Emergency Department
Acute kidney injury (AKI) is a common diagnosis in the emergency department (ED), and urinary tract obstruction is a contributing cause that requires rapid diagnosis and therapeutic management.
- Trial name
- NCT06040736
- Where
- France
- Volunteers
- 155 people
- Sponsor
- University Hospital, Montpellier
Out-of-Hospital Cardiac Arrest
Implementation of Gold Standard EMS CPR Programs for 2% Improvement in Survival Rates of Out-of-Hospital Cardiac Arrest in a Metropolitan City
This study aims to improve the survival rate of out-of-hospital cardiac arrest patients by 2% through a bundle of three intervention measures including: 1) dispatcher-assisted CPR, 2) multi-tiered response team CPR, and 3)…
- Trial name
- 2% Project (NCT02540629)
- Testing
- Bundled EMS CPR approach including dispatcher-assisted CPR, 3-person team CPR, and feedback CPR monitoring device
- Where
- South Korea
- Volunteers
- 12,670 people
- Sponsor
- Seoul National University Hospital
Pneumonia, Pneumonia - Bacterial
Derivation and Validation of the Risk Evaluation Score for Pneumonia Involving Resistant Entities (RESPIRE)
This is a single-center, non-profit observational study with two sequential phases: an initial retrospective phase followed by a prospective phase. Patients were enrolled during two consecutive, non-overlapping periods.
- Conditions
- Pneumonia, Pneumonia - Bacterial, Multi Drug Resistant, Multi Drug Resistant Organisms
- Trial name
- RESPIRE (NCT07425561)
- Testing
- RESPIRE score
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Difficult Intravenous Access, Midline Catheter
Single Lumen Midline Catheter vs Long Peripheral Intravenous Cather for Difficult Intravenous Access in the ED
Many patients in the emergency department have veins that are difficult to get an intrevenous (IV) catheter into (called "difficult IV access").
- Conditions
- Difficult Intravenous Access, Midline Catheter, Peripheral Intravenous Catheter, Emergency Department Patient
- Trial name
- NCT06668766
- Testing
- 10-cm Single Lumen Mildine, 4.78 cm Long Peripheral Intravenous Catheter
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- Albany Medical College
Geriatric Patients
Use of Telemedicine for Geriatric Emergency Patients
The aim of the present study is the implementation of a telemedical geriatric co-evaluation in the area of the emergency department. The use of telemedicine is intended to improve the care of geriatric emergency patients.
- Trial name
- NCT04148027
- Testing
- Treatment recommendation by emergency department physicians, Treatment recommendation by telemedical geriatric co-evaluation
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- RWTH Aachen University
Fever
Treatment Of Fever In The Emergency Department
Fever is a frequent cause of admission to the Emergency Department (ED) around the world. While it can be caused by a wide range of conditions, the most effective treatment based on its etiology is still undetermined.
- Trial name
- NCT05814302
- Testing
- Paracetamol
- Where
- Italy
- Volunteers
- 324 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Mental Disorders, Metabolism Medication Toxicity
Pharmacogenomic Profiling of Pediatric Patients
The purpose of this study is to determine the proportion of children presenting to a pediatric emergency department with an acute mental health/behavioral crisis or clinical drug toxicity who have a "match" or "mismatch" between…
- Conditions
- Mental Disorders, Metabolism Medication Toxicity, Pediatric Disorder
- Trial name
- NCT02770339
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Alabama at Birmingham
Hypobaric Hypoxia, Hypobaric Normoxia
Cognition at Altitude in HEMS - Part II
The aim of the current study is to evaluate under blinded conditions, both in a simulated environment and during helicopter flight, the effect of a rapid (within 20 minutes) exposure to altitude (4000 m asl) on physiological…
- Conditions
- Hypobaric Hypoxia, Hypobaric Normoxia, Cognitive Performance, Emergency Medicine
- Trial name
- HEMS II (NCT05073406)
- Testing
- Altitude exposure in hypobaric normoxic condition, Altitude exposure in hypobaric hypoxic condition
- Where
- Italy
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Institute of Mountain Emergency Medicine
Knowledge, Attitudes, Practice
GEMAS Proyect. Gamification in Nursing and Medicine for Simulation Learning.
The GEMAS project is based on the creation of a virtual serious game in which, by carrying out clinical cases that simulate real environments and episodes of a hospital emergency service, the aim is to improve and reinforce the…
- Trial name
- NCT06516250
- Testing
- Virtual serious game GEMAS
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Consorci Sanitari de Terrassa
Pain, Hypoglycemia
Outcomes Study of MTM in a Medicare ACO
This is a non-randomized, prospective, quasi-experimental study designed to assess the impact of pharmacist-provided medication management on total cost of care and clinical outcomes (ie, hospitalizations, emergency department…
- Trial name
- NCT02875925
- Testing
- MTM
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- HealthEast Care System