Clinical trials: EMERGENCY MEDICINE
Adverse Drug Event
Effectiveness of an ADE-related Hospitalization Risk Prediction Tool for Patients (ADE-RED)
The rationale for this study is to evaluate the effectiveness of a risk prediction tool for patients who are at high risk for ADEs resulting in hospitalization or ED revisit.
- Trial name
- NCT04181775
- Testing
- ADE-RED scoring tool
- Where
- United States
- Volunteers
- 471 people
- Sponsor
- Methodist Health System
Drug Abuse
Screening, Brief Intervention, and Referral to Treatment for Drug Use
Screening, Brief Intervention, and Referral to Treatment (SBIRT) is a comprehensive, integrated public health approach to identify and deliver a spectrum of early detection and intervention services for substance use in general…
- Trial name
- SBIRT (NCT01683227)
- Testing
- Screening/motivational drug intervention
- Where
- 2 sites in United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Drug Poisoning
StO2 Performance Measured on Admission to the Emergency Department in the Assessment of Drug Poisoning
The primary purpose of the protocol is to evaluate the StO2 performance measured at the admission to the emergency department to identify hemodynamic failure at the admission or within the first three hours of monitoring patients…
- Trial name
- IMACS (NCT01861262)
- Testing
- Measurement of StO2
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Toulouse
Heart Failure
Identifying Diuretic Resistance in Patients With Acute Heart Failure
The study team hypothesizes patients at risk for diuretic resistance can be identified early in their Emergency Department (ED) or hospital stay by evaluating their urine sodium and potassium concentration after an initial dose…
- Trial name
- NCT02751242
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Vanderbilt University
Heart Disease, Myocardial Infarction
Pre-hospital Administration of Thrombolytic Therapy With Urgent Culprit Artery Revascularization
The PATCAR study has been designed to test the hypothesis that the strategy of pre-hospital use of a "clot busting" (thrombolytic) drug followed with emergent heart catheterization including stenting of the problematic coronary…
- Conditions
- Heart Disease, Myocardial Infarction, Acute Myocardial Infarction
- Trial name
- PATCAR (NCT00178620)
- Testing
- Reteplase 10 Units (U) plus a second dose of reteplase 10 U, Reteplase 10 U, Urgent Percutaneous Coronary Intervention (PCI)
- Where
- United States
- Volunteers
- 390 people
- Sponsor
- The University of Texas Health Science Center, Houston
Epistaxis
Topical Intranasal Tranexamic Acid for Epistaxis in the Emergency Department
It is estimated that epistaxis results in 4.5 million emergency department visits per year throughout the United States. Due to the adverse effects of standard treatment options for epistaxis, tranexamic acid (TXA) may be…
- Trial name
- NCT02930941
- Testing
- Tranexamic Acid, 0.9% Sodium Chloride
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of California, Davis
Pediatric Anxiety
Non-Wearable Audiovisual Distraction for Children's Medical Anxiety in the ED
Pediatric emergency department (ED) visits often cause significant anxiety and stress for young patients due to unfamiliar environments and invasive medical procedures.
- Trial name
- NCT07761637
- Testing
- Non-Wearable Audiovisual Distraction, Routine ED Care
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- National Taiwan University Hospital
Acute Pain, İnjection
Comparison of the Efficacy of Shotblocker and Acupressure in Reducing Pain Due to Intramuscular Injection
Various non-pharmacological approaches are used in the relief of pain caused by intramuscular injection. Shotblocher and acupressure, which are among these methods, are easy to apply.More evidence-based studies are needed to…
- Conditions
- Acute Pain, İnjection, Acupressure, Alternative Medicine
- Trial name
- NCT05456945
- Testing
- acupressure application, Shotblocher
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Atrial Fibrillation and Flutter
Oral vs Intravenous Diltiazem for Rapid Atrial Fibrillation/Flutter Trial
The primary objective of this study is to compare the incidence of rate control (defined as: HR <110 beats/min or conversion to sinus rhythm) at 2 hours after medication administration between oral immediate release diltiazem and…
- Trial name
- OVID RAF (NCT03472495)
- Testing
- Diltiazem Oral Product, Diltiazem Injectable Product
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Virginia Commonwealth University
Pain
Prevention of Post Herpetic Neuralgia by Ultrasound Guided Single Nerve Block in the ED
Herpes zoster causes significant morbidity on over 1 million Americans every year. Although the majority of herpes zoster pain will self-resolve within one week, a significant proportion of patients will develop postherpetic…
- Trial name
- NCT04530162
- Testing
- Ultrasound guided nerve block
- Where
- United States
- Sponsor
- Antonios Likourezos
Telemedicine Usage, Teleconsultation Usage
Implementation Strategy and Systemic Effects of Routine Telemedical Care in Prehospital Emergency Medicine
In two research projects a comprehensive prehospital telemedicine system was developed and general feasibility as well as impact on guideline adherence were evaluated.
- Conditions
- Telemedicine Usage, Teleconsultation Usage, Emergency Medical Service Missions
- Trial name
- NCT04127565
- Volunteers
- 51,649 people
- Sponsor
- RWTH Aachen University
Number of Emergency Department and Hospital Visits Among Adults Experiencing Homelessness, Medication Adherence
Interactive Care Coordination and Navigation:RCT To Assess the Impact of a mHealth Intervention for Homeless Individuals
People experiencing homelessness (PEH) are at exceptionally high risk of frequent emergency department (ED) and hospital use, poor functional outcomes, and increased morbidity and mortality from poorly managed chronic health…
- Conditions
- Number of Emergency Department and Hospital Visits Among Adults Experiencing Homelessness, Medication Adherence, Social Support, Pyschological Distress
- Trial name
- iCAN (NCT05365867)
- Testing
- iCAN Group
- Where
- 3 sites in United States
- Volunteers
- 120 people
- Sponsor
- Leticia R. Moczygemba
Advanced Cancer, Metastatic Cancer
Emergency Department-Based Palliative Care for Advanced Cancer Patients
The purpose of this study is to: 1) identify the palliative care needs of Emergency Department patients with advanced cancer, and determine if these needs can be rapidly assessed in the ED; 2) determine whether early palliative…
- Trial name
- NCT01358110
- Testing
- Early palliative care consultation, Care as usual
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Medication Adherence, Hypertension
Pharmaceutical Care in Emergency Department
The purpose of this study is to evaluate the effectiveness of pharmaceutical care, compared to usual care, in patient discharge in an emergency department in patients with hypertension and/or diabetes mellitus type 2.
- Conditions
- Medication Adherence, Hypertension, Diabetes Mellitus
- Trial name
- AMPaRAR (NCT01978925)
- Testing
- Pharmaceutical care
- Where
- Brazil
- Volunteers
- 380 people
- Sponsor
- Hospital Moinhos de Vento
Supraventricular Tachycardia (SVT)
Adenosine vs Diltiazem for Treatment of SVT in the ED
This is a small, pilot study with a primary goal of assessing patient perceptions of two medication treatments for supraventricular tachycardia in adult patients treated in the Emergency Department.
- Trial name
- COMFORT-ED (NCT06993038)
- Testing
- adenosine, diltiazem
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Anne E. Zepeski
Low Back Pain
Morphine Versus Morphine-promethazine Combination for Acute Low Back Pain Relief in the Adult Emergency Department
Acute low back pain is a common cause for emergency department visits. Controversy remains regarding the optimal medication for acute low back pain relief.
- Trial name
- NCT01129934
- Testing
- Morphine-Promethazine, morphine
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Superficial Vein Thrombosis, D-dimer
Superficial Vein Thrombosis Testing in the Emergency Department
Superficial vein thrombosis (SVT) occurs when blood in a vein directly under the skin clots. SVT causes vein tenderness, pain, and skin discolouration. Over time, the vein hardens into a firm, nontender, easily palpable lump.
- Trial name
- SVTest (NCT07671300)
- Testing
- D-dimer
- Where
- Canada
- Volunteers
- 400 people
- Sponsor
- Dr. Kerstin de Wit
Poison;Medicinal, Extracorporeal Membrane Oxygenation
Treatment of Extracorporeal Membrane Oxygenation in Severe Poisoning
This is a prospective, multicentre clinical study to determine the value of the Extracorporeal Membrane Oxygenation in the treatment of critically ill poisoning patients and whether there are significant differences in the…
- Trial name
- NCT05762029
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Affiliated Hospital of Nantong University
Alcohol Dependence, Alcohol Use Disorder
Extended-release Naltrexone and Care Management for Alcohol Dependent Frequent Emergency Department Users
Our primary aim is to assess the feasibility of initiating treatment in the ED with extended-release naltrexone (XR-NTX) plus care management (CM) vs.
- Trial name
- NCT02445339
- Testing
- XR-NTX+CM (Extended-Release Naltrexone plus Care Management)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- NYU Langone Health
Cardiopulmonary Resuscitation, Echocardiography
Live Stream of Prehospital point-of Care Ultrasound During Cardiopulmonary Resuscitation
Background: Point-of-care ultrasound (POCUS) has been suggested as a useful tool in out-of-hospital cardiac arrest (OHCA) for diagnosis and treatment of reversible causes.
- Conditions
- Cardiopulmonary Resuscitation, Echocardiography, Ultrasound
- Trial name
- NCT04817475
- Testing
- Point-of-care ultrasound with tele-supervision
- Where
- Austria
- Volunteers
- 44 people
- Sponsor
- Medical University of Vienna