Clinical trials: EMERGENCY MEDICINE
Syncope
Syncope Decision Aid for Emergency Care
Syncope, or transient loss of consciousness/fainting, is a common emergency department (ED) complaint responsible for over 1 million ED visits yearly.
- Trial name
- SynDA (NCT02971163)
- Testing
- SynDA
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Cardiac and Respiratory Arrest
SST in Emergency Education
This study looks back at how the investigatorsll two different teaching methods work for training medical and nursing students in CPR (cardiopulmonary resuscitation), a life-saving emergency procedure used when someone's heart…
- Trial name
- SST (NCT07803861)
- Testing
- case-based scenario simulation teaching
- Where
- China
- Volunteers
- 69 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Community-Acquired Pneumonia, Fraility
Frailty and Outcomes in Older Emergency Department Patients With Pneumonia
Pneumonia is one of the leading causes of infection-related mortality in the older population. Traditional severity scores used in emergency departments, such as the Pneumonia Severity Index (PSI) and CURB-65, primarily focus on…
- Conditions
- Community-Acquired Pneumonia, Fraility, Hospitalizations
- Trial name
- NCT07442656
- Testing
- Clinical frailty scale, Clinical Frailty Scale (CFS)
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Ege University
Adverse Drug Events, Adverse Drug Reactions
The Effect of Medication Review in High-risk Emergency Department Patients
Adverse drug events are unintended and harmful events related to medication use and a leading cause of emergency department visits, unplanned hospital admissions and deaths.
- Conditions
- Adverse Drug Events, Adverse Drug Reactions, Medication-related Problems
- Trial name
- NCT02122965
- Testing
- Pharmacist-led medication review
- Where
- 3 sites in Canada
- Volunteers
- 10,805 people
- Sponsor
- University of British Columbia
Adverse Drug Event
Impact of an Optimized Communication on the Readmission for Adverse Drug Event
Emergency departments (EDs) are a crucial element of health care systems as they constitute the interface between hospital and communities.
- Trial name
- URGEIM (NCT03725046)
- Testing
- Optimized information transmission
- Where
- France
- Volunteers
- 346 people
- Sponsor
- University Hospital, Montpellier
Insomnia, Nightmares Associated With Trauma and Stress
Restorative Early Sleep Treatment After the Emergency Department
The goal of this randomized controlled trial is to pilot the virtual delivery of cognitive behavioral therapy for insomnia (CBT-I) and nightmares (CBT-I\&N) via telehealth as an early intervention for treating posttraumatic sleep…
- Conditions
- Insomnia, Nightmares Associated With Trauma and Stress, Nightmares, PTSD - Post Traumatic Stress Disorder
- Trial name
- RESTED (NCT07121270)
- Testing
- Cognitive Behavioral Therapy for Insomnia, Cognitive Behavioral Therapy for Insomnia and Nightmares, Sleep Education
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Henry Ford Health System
Geriatric Patients
Use of Telemedicine for Geriatric Emergency Patients
The aim of the present study is the implementation of a telemedical geriatric co-evaluation in the area of the emergency department. The use of telemedicine is intended to improve the care of geriatric emergency patients.
- Trial name
- NCT04148027
- Testing
- Treatment recommendation by emergency department physicians, Treatment recommendation by telemedical geriatric co-evaluation
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- RWTH Aachen University
Human Immunodeficiency Virus (HIV), Hepatitis C (HCV)
Persuasive Health Communication Intervention for HIV/HCV
A major impediment to emergency department (ED)-based HIV/HCV screening success is that often ED patients at risk for, or later diagnosed with, HIV and HCV decline testing.
- Trial name
- NCT05968573
- Testing
- Video Format with Captions, Video Format without Captions, Health Educator
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Acute Pain, İnjection
Comparison of the Efficacy of Shotblocker and Acupressure in Reducing Pain Due to Intramuscular Injection
Various non-pharmacological approaches are used in the relief of pain caused by intramuscular injection. Shotblocher and acupressure, which are among these methods, are easy to apply.More evidence-based studies are needed to…
- Conditions
- Acute Pain, İnjection, Acupressure, Alternative Medicine
- Trial name
- NCT05456945
- Testing
- acupressure application, Shotblocher
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Low Back Pain, Headache
Safe Harbors in Emergency Medicine, Specific Aim 3
Many patients who present to the emergency department (ED) receive a vast array of diagnostic tests, some of which might not be useful.
- Conditions
- Low Back Pain, Headache, Head Injury, Minor
- Trial name
- NCT05410366
- Testing
- Safe harbor clinical practice guideline
- Where
- United States
- Sponsor
- Vanderbilt University Medical Center
Fracture, Bone Fracture
AI Assisted Detection of Fractures on X-Rays (FRACT-AI)
This study has been added as a sub study to the Simulation Training for Emergency Department Imaging 2 study (ClinicalTrials.gov ID NCT05427838).
- Conditions
- Fracture, Bone Fracture, Dislocation, Fracture Multiple
- Trial name
- FRACT-AI (NCT06130397)
- Testing
- Cases reading, Ground truthing
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Oxford University Hospitals NHS Trust
Violence, Violence, Non-accidental
Optimization Study of the Wraparound Care for Youth Injured by Violence Program
This study is an optimization study to evaluate how a wraparound program for youth who have been injured by violence helps to change violence related attitudes and beliefs, change individual risk factors for violence and reduce…
- Conditions
- Violence, Violence, Non-accidental, Physical Violence
- Trial name
- NCT02573480
- Testing
- Wraparound care
- Where
- Canada
- Volunteers
- 11 people
- Sponsor
- University of Manitoba
Wounds and Injuries, Out-of-Hospital Cardiac Arrest
Psychoactive Drug Use and Acute Care Use After Trauma and Out-of-Hospital Cardiac Arrest
This retrospective population-based cohort study uses linked administrative healthcare data from the Local Health Authority of Bologna (Italy) to describe the use of four classes of psychoactive drugs (opioids, antiepileptics…
- Conditions
- Wounds and Injuries, Out-of-Hospital Cardiac Arrest, Traumatic Brain Injury
- Trial name
- LIFT-C (NCT07882589)
- Testing
- Opioids (ATC N02A), Antiepileptics (ATC N03A), Antipsychotics (ATC N05A)
- Where
- 2 sites in Italy
- Volunteers
- 52,720 people
- Sponsor
- Azienda Usl di Bologna
Trauma
Accuracy and External Validation of mREMS in Road Traffic Injuries
The goal of this prospective observational study is to assess the accuracy and external validation of the Modified Rapid Emergency Medicine Score (mREMS) in predicting outcomes for patients with road traffic injuries (RTIs)…
- Trial name
- AVE-MREMS (NCT06740409)
- Where
- Iraq
- Volunteers
- 292 people
- Sponsor
- Al-Nahrain University
Hemorrhage, Thrombosis
Adverse Drug Events in Patients on Oral Anticoagulation in the Emergency Department
Rationale: According to the latest National Survey on Care-Related Adverse Events, anticoagulants, including vitamin K antagonists (VKAs), rank first among medications responsible for serious iatrogenic accidents (37% in 2004…
- Conditions
- Hemorrhage, Thrombosis, Anticoagulant Therapy, Traumatic Hemorrhage
- Trial name
- ADEOA (NCT06692504)
- Where
- France
- Volunteers
- 2,080 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Old Age; Debility, Health Services for the Aged
Physiotherapy Led Community Intervention for Older Adults Discharged From the Emergency Department
ED PLUS Emergency Department Discharge Physiotherapy Led Community Service is a pilot feasibility randomized controlled trial investigating the role of an integrated care intervention consisting of comprehensive geriatrics…
- Trial name
- EDPLUS (NCT04983602)
- Testing
- Comprehensive Geriatric Assessment arm, EDPLUS
- Where
- Ireland
- Volunteers
- 29 people
- Sponsor
- University of Limerick
Migraine
A Comparison of Nurtec ODT to Maxalt MLT-ODT in Adult ED Patients With Migraine Headache
Rimegepant (Nurtec) is an orally administered small molecule CGRP receptor antagonist with efficacy in the acute treatment of migraine.
- Trial name
- NCT06473597
- Testing
- Rimegepant, Rizatriptan Benzoate
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Antonios Likourezos
Status Epilepticus
Paramedic Treatment of Prolonged Seizures by Intramuscular Versus Intravenous Anticonvulsant Medications
The goal of this non-inferiority trial is to determine which type of routine care is the best for paramedics to stop someone from seizing.
- Trial name
- RAMPART (NCT00809146)
- Testing
- Intramuscular route of active treatment, Intravenous route of active treatment
- Where
- 17 sites in United States
- Volunteers
- 1,023 people
- Sponsor
- Robert Silbergleit
Need to Refer the Patient to the Hospital Emergency Department
Artificial Intelligence Triage of Patients Requiring Emergency or Unscheduled Care Who Need to be Referred to Hospital
For several decades, hospital emergency departments have been experiencing congestion, sometimes reaching saturation point, where they are no longer able to fulfil their primary mission: to prioritise patients requiring immediate…
- Trial name
- TRIAGE (NCT07428109)
- Where
- France
- Volunteers
- 40,680 people
- Sponsor
- SOS Médecins Grand Paris
Dyspnea, Emergencies
Blue Protocol Assessment
Acute dyspnea is a common disease in emergency medicine. Mortality remains high is estimated at 15%. One third of initial diagnoses before paraclinical examination are estimated to be inaccurate.
- Trial name
- Blue P (NCT04223297)
- Testing
- lung ultrasound
- Where
- France
- Volunteers
- 115 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens