Clinical trials: ERCP
Anxiety, Biliary Tract Diseases
Nurse-Led Education Before ERCP: Effects on Patient Knowledge and Anxiety
Endoscopic retrograde cholangiopancreatography (ERCP) is an invasive procedure frequently accompanied by preprocedural anxiety, which has been associated with altered physiological parameters, reduced procedural tolerance, higher…
- Conditions
- Anxiety, Biliary Tract Diseases, Pancreatic Diseases
- Trial name
- ERCP-EDU (NCT07805577)
- Testing
- Structured nurse-led preprocedural education, Routine information
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gazi University
Chronic Pancreatitis, Chronic Pain
Pancreatic Quantitative Sensory Testing (P-QST) to Predict Treatment Response for Pain in Chronic Pancreatitis
Abdominal pain in chronic pancreatitis (CP) affects up to 90% of patients during the course of their disease, and response to currently available therapies is suboptimal and unpredictable.
- Trial name
- P-QST (NCT04996628)
- Testing
- Quantitative Sensory Test 1, Quantitative Sensory Test 2, Quantitative Sensory Test 3
- Where
- 3 sites in United States
- Volunteers
- 150 people
- Sponsor
- University of Pittsburgh
Laparoscopic Cholecystectomy
Laparoscopic Cholecystectomy After ERCP
Evaluation of outcomes of early and late laparoscopic cholecystectomy after ERCP
- Trial name
- NCT06197373
- Testing
- Laparoscopic cholecystectomy
- Volunteers
- 60 people
- Sponsor
- Mohamed Bakr Mohamed Ahmed
Intraductal Papillary Mucinous Neoplasm
SpyGlass in Preoperative Diagnostics of Presumed Main Duct IPMNs: Efficacy and Novel Insights on Complications
Distinguishing intraductal papillary mucinous neoplasms (IPMNs) from other pancreatic cystic lesions is essential as IPMNs bear risk of becoming malignant.
- Trial name
- NCT03062124
- Testing
- SpyGlass pancreatoscopy
- Where
- 3 sites in Finland, Sweden
- Volunteers
- 101 people
- Sponsor
- Helsinki University Central Hospital
Obese
HFNO Versus Nasal CPAP in Obese Patients Undergoing Deep Sedation for ERCP
Endoscopic retrograde cholangio-pancreatography (ERCP) is commonly performed under deep sedation to provide amnesia, comfort, and optimal procedural conditions.
- Trial name
- NCT04912102
- Testing
- high flow nasal oxygen device (HFNO)
- Volunteers
- 270 people
- Sponsor
- Assiut University
Pancreatitis
High Volume Lactated Ringer's Solution and Pancreatitis
The purpose of this study is to examine whether giving large amounts of intravenous (IV) fluids will reduce the risk of developing a complication known as post-ERCP pancreatitis (PEP).
- Trial name
- NCT02050048
- Testing
- Administration of Lactated Ringer's (LR) Solution
- Where
- 6 sites in United States
- Volunteers
- 26 people
- Sponsor
- Endeavor Health
Difficult Biliary Cannulation
A Convolutional Neural Network for Difficult Biliary Cannulation
The main purpose of the study is to train a convolutional neural network (CNN) to predict difficult biliary canulation (DBC) following the European Society of Gastrointestinal Endoscopy Society (ESGE).
- Trial name
- PRECABIDO2 (NCT07389915)
- Testing
- Endoscopic retrograde cholangiopancreatography (ERCP)
- Volunteers
- 600 people
- Sponsor
- University of La Laguna
ERCP, Pancreatitis
Efficacy Study of Glyceryl-Trinitrate Patch and Parecoxib (Valdecoxib) for the Prevention of Pancreatitis After Endoscopic Retrograde Cholangiopancreatography (ERCP)
ERCP is a diagnostic and therapeutic procedure that is required in patients with suspected common bile duct stone, malignant biliary obstruction, biliary fistula, etc.
- Trial name
- NCT00419549
- Testing
- Glyceryl - trinitrate, Valdecoxib
- Where
- India
- Volunteers
- 371 people
- Sponsor
- All India Institute of Medical Sciences
Malignant Tumor of Extrahepatic Bile Duct
Winged Perimeter Versus Traditional Plastic Biliary Stent for Malignant Bile Duct Obstruction
Strictures in the bile duct cause a blockage of flow of bile. This leads to potential problems including jaundice, itch and infection in the bile duct.
- Trial name
- NCT01514214
- Testing
- WInged perimeter biliary stent insertion (Viaduct), traditional polyethylene stent insertion (Cotton Huibregtse)
- Where
- 2 sites in Canada
- Volunteers
- 58 people
- Sponsor
- University of British Columbia
Biliary Stones
Spyglass DS Peroral Cholangioscope Guided LL or EHL Versus BML for Endoscopic Removal of Complicated Bile Duct Stones
This study aims to compare the overall rate of endoscopic clearance of complicated bile duct stones by Spyglass DS peroral cholangioscopy guided holmium:YAG laser/electrohydraulic lithotripsy versus conventional BML.
- Trial name
- NCT03244163
- Testing
- Spyglass DS cholangioscope, BML
- Where
- Hong Kong
- Volunteers
- 86 people
- Sponsor
- Chinese University of Hong Kong
ERCP Surgery
Evaluation of the Benefit of Lidocaine on the Prevention of the Risk of Post Endoscopic Retrograde Cholangio-pancreatography Pancreatitis.
The goal of this study is, in a population of patients undergoing ERCP surgery, treated preventively with NSAIDs and divided into two groups according to the absence (group 1) or presence (group 2) of intravenous lidocaine in the…
- Trial name
- PEPLID (NCT05667987)
- Testing
- Intravenous lidocaine administration
- Where
- France
- Volunteers
- 1,800 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Acute Pancreatitis (AP), Gallstone Pancreatitis
Pentoxifylline Treatment in Acute Pancreatitis (AP)
The purpose of this study was to determine the effects (good and bad) of giving a drug called pentoxifylline to patients with acute pancreatitis.
- Conditions
- Acute Pancreatitis (AP), Gallstone Pancreatitis, Alcoholic Pancreatitis, Trauma Acute Pancreatitis
- Trial name
- AP (NCT02487225)
- Testing
- Pentoxifylline
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- Mayo Clinic
Hemodynamic Instability
Advanced vs Standard Hemodynamic Monitoring During Propofol Sedation for ERCP: A Prospective Study
The aim of this study is to evaluate whether there is a difference in hemodynamic events requiring intervention between patients monitored with advanced hemodynamic monitoring using the MostCare system and those monitored with…
- Trial name
- NCT07538115
- Testing
- Hemodynamic Monitoring, Standard Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Hitit University
Pancreatitis
Rectal Indomethacin With or Without Papillary Ice Water Irrigation to Prevent Post-ERCP Pancreatitis
Post-endoscopic retrograde cholangiopancreatography pancreatitis (post-ERCP pancreatitis, or PEP) is inflammation of the pancreas that can occur after an ERCP procedure.
- Trial name
- N-ICE (NCT07826026)
- Testing
- Rectal Indomethacin, Papillary Ice Water Irrigation
- Volunteers
- 120 people
- Sponsor
- Unity Health Toronto
Endoscopic Retrograde Cholangiopancreatography
Initial Case Series With Exalt Single-Use Duodenoscope
To confirm procedural performance of the Exalt single-use duodenoscope in Endoscopic Retrograde Cholangio-Pancreatography (ERCP) procedures.
- Trial name
- NCT03701958
- Testing
- Exalt Model D Single-Use Duodenoscope
- Where
- 6 sites in United States
- Volunteers
- 60 people
- Sponsor
- Boston Scientific Corporation
Biliary Obstruction
Cost Analysis for Endoscopic Retrograde Cholangiopancreatography (ERCP)
The purpose of the study is to determine if endoscopist notification of accessory cost results in altered resource utilization related to the total cost and number of accessories used in ERCP.
- Trial name
- ERCP (NCT02127229)
- Testing
- Endoscopist informed of cost per procedure
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Oklahoma
Intubation;Difficult
If Different Types of Periampullary Diverticula Affect ERCP Cannulation?
To study the influence of different types of periampullary diverticulum(PAD) on ERCP difficult cannulation and postoperative complications.
- Trial name
- NCT03556072
- Testing
- Routine ERCP
- Where
- China
- Volunteers
- 700 people
- Sponsor
- Hepatopancreatobiliary Surgery Institute of Gansu Province
Stone - Biliary
Effect of Saline Irrigation in Reducing Choledocholithiasis Recurrence After ERCP
In this prospective study, the investigators assessed the utility of intermittent saline irrigation in reducing the recurrent rate of choledocholithiasis after the endoscopic extraction for common bile duct stones, and it does…
- Trial name
- NCT03937037
- Testing
- Saline irrigation
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Hepatopancreatobiliary Surgery Institute of Gansu Province
the Severity and Duration of Intraoperative Hypotension
Remimazolam in High Risk ERCP Patients
We conducted a randomized trial to investigate whether the administration of Remimazolam in patients undergoing high-risk endoscopic retrograde cholangiopancreatography (ERCP) could significantly reduce the occurrence of…
- Trial name
- NCT06258356
- Testing
- Remimazolam
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Cognitive Impairment
Assessment of Cognitive and Functional Impairment in Older Patients After ERCP
Endoscopic retrograde cholangiopancreatography (ERCP) is an interventional endoscopy procedure utilized in the therapeutic management of pancreatobiliary diseases including gallstones, bile duct strictures, leaks and infections…
- Trial name
- NCT03762954
- Testing
- Neurocognitive function assessment
- Where
- United States
- Volunteers
- 215 people
- Sponsor
- Vanderbilt University Medical Center