Clinical trials: ERCP
Post-ERCP Acute Pancreatitis
Study of Forceps Cannulation During ERCP
A difficult cannulation has been identified as one of the high risk factors for developing post-ERCP pancreatitis (PEP). The accessibility and morphology of the papilla influence the level of cannulation difficulty.
- Trial name
- SOCCER (NCT05336630)
- Testing
- Forceps
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Endoscopic Retrograde Cholangiopancreatography
Initial Case Series With Exalt Single-Use Duodenoscope - Expanded User Experience
The objective of this study is to confirm procedural performance of the Exalt Model D Single-Use Duodenoscope in Endoscopic Retrograde Cholangio-Pancreatography (ERCP) and other duodenoscope-based procedures.
- Trial name
- NCT04223830
- Testing
- Exalt Model D Single-Use Duodenoscope
- Where
- 7 sites in United States, Netherlands
- Volunteers
- 200 people
- Sponsor
- Boston Scientific Corporation
Post-ERCP Acute Pancreatitis
IV Ibuprofen for the Prevention of Post-ERCP Pancreatitis
Endoscopic retrograde cholangiopancreatography (ERCP) is an advanced endoscopic technique utilized to diagnose and treat pathologic conditions involving the ducts draining the liver and pancreas.
- Trial name
- NCT02241512
- Testing
- Ibuprofen
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- University of Texas Southwestern Medical Center
Choledocholithiasis, Cholangiocarcinoma
Etomidate vs. Midazolam for Sedation During ERCP
Recently up-coming drug, etomidate which is a modulator of GABA(gamma-Aminobutyric acid)-A receptor has been known that it maintains the appropriate sedative levels and affects little effects on respiratory system.
- Conditions
- Choledocholithiasis, Cholangiocarcinoma, Pancreatitis, Pancreatic Cancer
- Trial name
- NCT02027311
- Testing
- Etomidate, Midazolam, Meperidine
- Where
- South Korea
- Volunteers
- 63 people
- Sponsor
- Cheju Halla General Hospital
Bile Duct Stricture, Choledocholithiasis
Prospective Study to Investigate the Frequency of Possible Bacterial Entry Into the Bloodstream (Bacteremia) and Infectious Complications Associated With the Use of the Spyglass Cholangioscopy System During ERCP (Endoscopic Retrograde Cholangiopancreatography).
The aim of this study is to prospectively evaluate the frequency of bacteremia after ERCP/cholangioscopy using the Spyglass Direct Visualization System.
- Trial name
- NCT01414400
- Testing
- Blood draw for culture
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Stanford University
Post-ERCP Acute Pancreatitis
Lactated Ringers With or Without Rectal Indomethacin to Prevent Post-ERCP Pancreatitis
Post-ERCP pancreatitis is a well-known and sometimes life-threatening complication of ERCP. Both LR and rectal indomethacin have shown benefit in preventing post-ERCP pancreatitis.
- Trial name
- IND+LRPEP (NCT02641561)
- Testing
- Indomethacin, Lactated Ringer's Solution, Normal Saline
- Where
- United States
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- The Cooper Health System
Pancreatic Duct Stone, Pancreatic Duct Stricture
Pancreatic Endotherapy for Refractory Chronic Pancreatitis
The purpose of this study is to evaluate whether endoscopic ultrasound (EUS) only versus EUS + endoscopic retrograde cholangiopancreatography (ERCP) with pancreatic endotherapy reduces pain in the treatment of chronic…
- Conditions
- Pancreatic Duct Stone, Pancreatic Duct Stricture, Pancreatic Duct Dilatation
- Trial name
- PERCePT (NCT04232670)
- Testing
- EUS + Pancreatic Endotherapy
- Where
- 2 sites in United States
- Volunteers
- 14 people
- Sponsor
- Oregon Health and Science University
Hypoxemia
Does Capnography Prevent Hypoxemia During Endoscopic Retrograde Cholangiopancreatography and Endoscopic Ultrasound?
Subjects undergoing elective ERCP and EUS will receive standard monitoring and sedation. In addition, capnography which measures carbon dioxide levels and can graphically assess respiratory activity will be used.
- Trial name
- NCT00675415
- Testing
- Capnography
- Where
- United States
- Volunteers
- 263 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
ERCP, Pancreatic Diseases
Drotaverine Hydrochloride Versus Hyoscine-N-butylbromide for Duodenal Antimotility During Endoscopic Retrograde Cholangiopancreatography (ERCP)
The aim of the present study was to evaluate the use of drotaverine hydrochloride versus hyoscine-N-butylbromide in reducing duodenal motility during diagnostic and therapeutic ERCP.
- Conditions
- ERCP, Pancreatic Diseases, Bile Duct Diseases
- Trial name
- NCT00731198
- Testing
- Drotaverine hydrochloride, Hyoscine-N-butylbromide
- Where
- 4 sites in China
- Volunteers
- 650 people
- Sponsor
- Changhai Hospital
Post-ERCP Acute Pancreatitis
Rectal Indomethacin vs Intravenous Ketorolac
Endoscopic retrograde cholangiopancreatography (ERCP) is an essential procedure that can be complicated by post-ERCP pancreatitis (PEP). Indomethacin and ketorolac are two medications used to prevent PEP.
- Trial name
- NCT05664074
- Testing
- Rectal indomethacin, IV ketorolac
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- David Vitale MD
Pancreatitis, Pancreas Divisum
SpHincterotomy for Acute Recurrent Pancreatitis
The purpose of this study is to determine if a procedure called Endoscopic Retrograde CholangioPancreatography (ERCP) with sphincterotomy reduces the risk of pancreatitis or the number of recurrent pancreatitis episodes in…
- Conditions
- Pancreatitis, Pancreas Divisum, Pancreatitis, Acute, Pancreatitis Idiopathic
- Trial name
- SHARP (NCT03609944)
- Testing
- ERCP with miES, EUS
- Where
- 21 sites in United States, Canada
- Volunteers
- 181 people
- Sponsor
- Oregon Health and Science University
Bile Duct Carcinoma, Gallbladder Carcinoma
A Dual Channel Supraglottic Airway Device (LMA Gastro) for Oxygenation in Patients Undergoing ERCP
This clinical trial compares the effect of LMA Gastro, a dual channel supraglottic airway (SGA) device, to oxygenation with standard nasal cannula for endoscopic retrograde cholangiopancreatography (ERCP).
- Conditions
- Bile Duct Carcinoma, Gallbladder Carcinoma, Pancreatic Ductal Adenocarcinoma
- Trial name
- NCT04740164
- Testing
- Endoscopic Retrograde Cholangiopancreatography
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- M.D. Anderson Cancer Center
Conscious Sedation
Gabapentin to Improve Patient Tolerance in Endoscopic Retrograde Cholangiopancreatography (ERCP)
The standard approach to sedation in endoscopic retrograde cholangiopancreatography (ERCP) involves the use of benzodiazepines and opiates to achieve a moderate depth of sedation.
- Trial name
- NCT01143766
- Testing
- Gabapentin, Standard sedation regimen
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Indiana University
Post-ERCP Acute Pancreatitis
Rectal Indomethacin to Prevent Post-Endoscopic Retrograde Cholangiopancreatography (ERCP) Pancreatitis
The purpose of this study is to assess whether peri-procedural administration of rectal indomethacin, compared to placebo, can reduce the incidence of post-ERCP pancreatitis.
- Trial name
- NCT01774604
- Testing
- Indomethacin
- Where
- United States
- Volunteers
- 449 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Bile Duct Diseases
Angled-tip vs. Straight-tip Guidewire in Biliary Cannulation
The investigators aim is to compare outcomes between an angled-tip guidewire and a straight-tip guidewire in cannulation of the common bile duct during ERCP. This is a randomized, controlled, single-blinded study.
- Trial name
- NCT05600270
- Testing
- Angled guidewire, Straight guidewire
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Neev Mehta
Post-ERCP Pancreatitis
Stent vs. Indomethacin for Preventing Post-ERCP Pancreatitis
Background: Pancreatitis is the most frequent complication of endoscopic retrograde cholangiopancreatography (ERCP), accounting for substantial morbidity, occasional mortality, and increased health care expenditures.
- Trial name
- SVI (NCT02476279)
- Testing
- Indomethacin 100 mg rectally immediately after ERCP, NO prophylactic pancreatic stent placement, Indomethacin 100 mg rectally immediately after ERCP AND prophylactic pancreatic stent placement
- Where
- 20 sites in United States, Canada
- Volunteers
- 1,950 people
- Sponsor
- Medical University of South Carolina
Endoscopic Retrograde Cholangiopancreatography
Global Prospective Case Series Using a Single-Use Duodenoscope
Confirm procedural performance of the ExaltTM Model D Single-Use Duodenoscope in Endoscopic Retrograde Cholangio-Pancreatography (ERCP) and other duodenoscope-based procedures
- Trial name
- NCT04103749
- Testing
- Exalt Model D Single-Use Duodenoscope
- Where
- 22 sites in United States, Australia and 9 more
- Volunteers
- 551 people
- Sponsor
- Boston Scientific Corporation
Pancreatitis
Topical Pancreatic Duct Lidocaine for Prevention of Post-ERCP Pancreatitis
The purpose of this study is to determine if lidocaine is effective in reducing the incidence of post-ERCP pancreatitis.
- Trial name
- NCT00953199
- Testing
- Lidocaine Hydrochloride, Normal Saline
- Where
- United States
- Volunteers
- 506 people
- Sponsor
- Abraham Mathew MD
Biliary Tract Diseases
Spy II Clinical Registry
A prospective, multi-center registry for subjects undergoing Endoscopic retrograde Cholangiopancreatography (ERCP) and cholangioscopy for known or suspected pancreaticobiliary disease.
- Trial name
- NCT00751998
- Testing
- SpyGlass
- Where
- 15 sites in United States, Belgium and 4 more
- Volunteers
- 297 people
- Sponsor
- Boston Scientific Corporation
Cholangiopancreatography, Endoscopic Retrograde, Biliary Stricture
Prospective Evaluation of Biliary Tissue Sampling With ERCP
The purpose of this study is to assess the safety, outcomes and performance characteristics of multiple biliary sampling techniques including but not limited to: single operator cholangioscopy (SOC) directed biopsies…
- Conditions
- Cholangiopancreatography, Endoscopic Retrograde, Biliary Stricture, Biliary Tract Diseases, Cholangiocarcinoma
- Trial name
- NCT04572711
- Where
- United States
- Volunteers
- 327 people
- Sponsor
- Mayo Clinic