Clinical trials: EUS-FNA
Adenocarcinoma, Neuroendocrine Tumors
EchoTip AcuCore Post-Market Clinical Study
The purpose of collecting this data is to continue to learn more about the EchoTip AcuCore and the device's ability to produce the desired favorable effect and if there are any undesired outcomes that may be related to the…
- Conditions
- Adenocarcinoma, Neuroendocrine Tumors, Hepatocellular Carcinoma, Cholangiocarcinoma
- Trial name
- NCT06358001
- Testing
- EchoTip AcuCore
- Where
- 8 sites in United States
- Volunteers
- 183 people
- Sponsor
- Cook Research Incorporated
Pancreatic Solid Lesions
The Comparison of Wet Suction and Dry Suction Technique in EUS-FNA for the Outcomes in Pancreatic Solid Lesions
The objective of this randomized controlled trial is to evaluate whether wet suction technique (WST), compared with dry suction technique (DST), shall present a better outcome with regard to the diagnostic yield and specimen…
- Trial name
- NCT03821974
- Testing
- wet suction technique, dry suction technique
- Where
- China
- Volunteers
- 50 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Pancreas Mass Diagnosis
Comparing Methods to Biopsy Pancreas Mass
This study will examine whether there is any difference in number of passes needed to diagnose pancreatic masses during endoscopic ultrasound-guided biopsies using 2 different types of needles.
- Trial name
- NCT01663493
- Testing
- FNB
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Brigham and Women's Hospital
Endoscopic Ultrasonography, EUS-FNA
Heparin-based Wet Suction Method in EUS Fine Needle Biopsy of Solid Pancreatic Mass
The objective of this randomized cross-over trial is to evaluate whether Heparin based wet suction technique, compared with dry suction technique, shall present a higher quality tissue core by using quantitative macroscopic and…
- Conditions
- Endoscopic Ultrasonography, EUS-FNA, Pancreatic Neoplasms
- Trial name
- NCT04707560
- Testing
- EUS fine needle biopsy with heparin wet suction
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Cheng-Kung University Hospital
Diagnoses Diseases, Ultrasound Therapy; Complications
19 Versus 22-Gauge Needle for EUS-LB
Chronic liver disorders (CLD) are a major cause of morbidity and mortality for individuals in the US. Though serologic analysis will often lead to a conclusive diagnosis, liver biopsy remains an important method for helping to…
- Conditions
- Diagnoses Diseases, Ultrasound Therapy; Complications, Liver Diseases
- Trial name
- EUSLB1922 (NCT02967991)
- Testing
- EUS-guided liver biopsy
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Geisinger Clinic
Endoscopic Ultrasonography-guided Fine Needle Aspiration, Sedation Complication
Safety and Efficacy Evaluation of Remimazolam for Endoscopic Ultrasound-guided Fine Needle Aspiration/Biopsy
This study aims to compare the safety and efficacy of remimazolam and propofol in EUS-FNA/FNB sedation. This study is a prospective, single-blind study.
- Conditions
- Endoscopic Ultrasonography-guided Fine Needle Aspiration, Sedation Complication, Remimazolam
- Trial name
- NCT05437497
- Testing
- Remimazolam Injection, Propofol Injection
- Where
- China
- Volunteers
- 264 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Liver Biopsy
Liver Biopsy Using a 19 Gauge Fine Needle Biopsy Needle
A 19 gauge FNB needle, using same technique as with 22 gauge needle, to obtain liver histological specimen in regards to core length and the number of Complete Portal Triads.
- Trial name
- NCT03910790
- Testing
- 19 gauge needle liver biopsy
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- AdventHealth
Biliary Strictures
Endoscopic Ultrasound-guided Fine-needle Biopsy for Tissue Sampling of Biliary Strictures: a Multicenter Prospective Study
After the disappointing results of first-generation reverse bevel fine-needle biopsy (FNB) needles, newer 'third generation' endoscopic ultrasound (EUS) needles were developed, known as the "end-cutting" needles.
- Trial name
- NCT06614452
- Testing
- EUS-FNB
- Where
- 2 sites in Italy
- Volunteers
- 45 people
- Sponsor
- Ospedali Riuniti di Foggia
Pancreatic Cancer
Feasibility of the Loop Brush EUS-FNA for Characterization of Pancreatic Cysts: Pilot Clinical Investigation
This investigation aims to demonstrate the feasibility of the lbFNA device for the first time in pancreatic cysts in humans. This study will be used as a base for further investigations on the safety and diagnostic accuracy of…
- Trial name
- PCLoop-Pilot (NCT07814326)
- Testing
- Loop Brush Fine Needle Aspiration
- Where
- Sweden
- Volunteers
- 8 people
- Sponsor
- Urban Arnelo
Pancreatic Cancer
Endoscopic Ultrasound (EUS) Guided Fine Needle Aspiration (FNA) EUS-FNA of Solid Pancreatic Mass Lesions Using a Novel Corkscrew Technique: a Pilot Study
This research is being done to investigate if a new technique to biopsy the pancreas will lead to a larger amount tissue material that can be analyzed.
- Trial name
- NCT02116322
- Testing
- EUS-FNA with Corkscrew technique, Expect 19 G Flex needle
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Johns Hopkins University
Pancreatic Cancer
Evaluation of Multiple Needle Use in EUS-FNA for Pancreatic Cancer
The aim of this study is to evaluate if the early change of needle during EUS-FNA for suspected pancreatic cancer allows an earlier preliminary cytological diagnosis of neoplasia.
- Trial name
- EMUNE-07 (NCT00548626)
- Testing
- Single needle, Multiple needle
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- University of Chicago
Lung Cancer
Surgical Versus Non-surgical Staging of Lung Cancer
About half of all lung cancers are caught after they have spread to nearby lymph nodes. Lymph nodes are small glands found throughout the body that remove bacteria and foreign particles (part of the immune system).
- Trial name
- NCT01117714
- Testing
- Integrated Staging for Early Detection of Metastases in Lung Cancer
- Where
- 3 sites in United States
- Volunteers
- 9 people
- Sponsor
- Medical University of South Carolina
Pancreas Disease, Liver Diseases
Motorized Fine Needle Biopsy vs Standard Needles
Recent improvements in punctures techniques and needles now allow for the collection of high-quality specimens comparable to core needle biopsy.
- Trial name
- NCT06298604
- Testing
- EUS-guided standard fine needle biopsy, EUS-guided motorized fine needle biopsy
- Where
- Ecuador
- Volunteers
- 60 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Pancreatic Cyst
New Biomarkers in the Intracystic Liquid of Inflammatory and Non-inflammatory Pancreatic Cysts
Due to the advances made in the field of the imaging techniques and their common use, pancreatic cysts are more and more incidentally found.
- Trial name
- NCT05568433
- Testing
- Endoscopic ultrasound fine needle aspiration (EUS-FNA)
- Where
- Romania
- Volunteers
- 63 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Pancreatic Cancer, Lymphadenopathy
Prospective Trial of EUS-FNA Versus EUS-FNB Using a Novel Core Biopsy Needle
Endoscopic ultrasound (EUS) is paramount in the diagnosis and evaluation of cancers involving the gastrointestinal tract. EUS allows for the acquisition of cellular (fine needle aspirate - FNA) or tissue biopsy (fine needle…
- Conditions
- Pancreatic Cancer, Lymphadenopathy, Gastrointestinal Stromal Tumor
- Trial name
- MUCIN (NCT01769248)
- Testing
- Fine needle aspiration, Fine needle biopsy
- Where
- 3 sites in United States
- Volunteers
- 140 people
- Sponsor
- Northwestern University
Mediastinal or Intra-abdominal Lymphadenopathy,, Pancreatic Masses,
A Randomized Controlled Trial Of Endoscopic Ultrasound-Guided Fine-Needle Aspiration With And Without A Stylet
Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) has become an important tool in the diagnostic evaluation of gastrointestinal tract lesions and other organ sites such as mediastinal and intra-abdominal…
- Conditions
- Mediastinal or Intra-abdominal Lymphadenopathy,, Pancreatic Masses,, Left Adrenal Masses,, Gastrointestinal Submucosal Lesions, and
- Trial name
- NCT01213290
- Testing
- EUS - FNA with stylet, Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA)
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- American Society for Gastrointestinal Endoscopy
Cancer of Pancreas, Pancreatic Neoplasm
Trial Comparing 19 and 25-gauge EUS-FNA Needles
This study compares the 19G and 25G needles for procuring tissue samples from the pancreas during Endoscopic Ultrasound (EUS) procedures.
- Trial name
- EUS-FNA (NCT01677312)
- Testing
- Pancreatic Biopsy, Histological Samples
- Where
- 2 sites in United States
- Volunteers
- 72 people
- Sponsor
- AdventHealth
Pancreatic Neoplasms
Diagnostic Yield of 20-gauge Procore Needle for EUS-guided FNA Biopsy in Solid Pancreatic Lesions
This study aims to examine technical feasibility and diagnostic yield of new 20-gauge Procore needle for EUS-guided fine needle biopsy in solid lesions by comparing with 22-gauge Procore needle.
- Trial name
- NCT02920944
- Testing
- EUS-FNB with 20 gauge ProCore needle, EUS-FNB with 22 gauge ProCore needle
- Where
- South Korea
- Volunteers
- 35 people
- Sponsor
- Seung Bae Yoon
Pancreatic Cancer
Prospective Evaluation of Diagnostic Accuracy of Endoscopic Ultrasound-guided Fine Needle Aspiration and Biopsy (EUS-FNAB) in the Absence of Rapid Onsite Evaluation
<Background/aims> Rapid onsite evaluation (ROSE) of endoscopic ultrasound-guided fine needle aspiration and biopsy (EUS-FNAB) specimens by attending cytopathologists has been demonstrated to improve diagnostic yields of EUS-FNAB.
- Trial name
- FNASROSE (NCT02079285)
- Testing
- EUS-FNA
- Where
- 2 sites in South Korea
- Volunteers
- 75 people
- Sponsor
- Kangbuk Samsung Hospital
Non Small Cell Lung Cancer
Study Comparing EBUS & EUS to Mediastinoscopy in Staging and Detection of Lung Cancer
This is a prospective randomized clinical trial with the study cohort comprised of all male and female patients over the age of 21 presenting to the study site for evaluation of lung cancer.
- Trial name
- NCT00970645
- Testing
- Mediastinoscopy/thoracoscopy, EBUS/EUS
- Where
- 3 sites in United States
- Volunteers
- 2 people
- Sponsor
- Mayo Clinic