Clinical trials: Early Child Development, open to volunteers
Autism Spectrum Disorder (ASD)
Associations of Autistic Traits and Feeding Difficulties
The objective is to assess the prevalence of autistic traits and feeding disorders in the general population.
- Trial name
- BAMBI2025 (NCT07188870)
- Where
- Hungary
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Down Syndrome, Trisomy 21
Executive Function Play Opportunities for Children With Down Syndrome
The Executive Function Play Opportunities (EXPO) study is a sequential, multiple assignment, randomized trial (SMART) evaluating adaptive caregiver-mediated intervention pathways for improving executive function (EF) in children…
- Trial name
- EXPO (NCT07792382)
- Testing
- EXPO, EXPO Extended, EXPO Foundations
- Where
- 2 sites in United States, Italy
- Volunteers
- 150 people
- Sponsor
- Colorado State University
Autism Spectrum Disorder, Autism
Early Diagnostic Telehealth Pilot for Moderate- and High-Risk Children: Evaluating Assessment Protocols and Efficiency in Georgia's Early Intervention Program
This pilot study includes children identified as moderate- as well as high-risk for autism spectrum disorder (ASD) within Georgia's Babies Can't Wait (BCW) Early Intervention (EI) program.
- Trial name
- NCT07623759
- Testing
- Early Diagnostic Response Model Expanded
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Emory University
Premature Baby, Neurocognition, Child
Longitudinal Assessment of Early Premature Infant Skills for Audiovisual Speech Perception
From birth, babies perceive speech face to face with their interlocutors in audiovisual situations (AV): in addition to hearing them (auditory speech), they will also, in most cases, be able to observe their speaking faces (ex…
- Trial name
- Pré-AV (NCT07245693)
- Testing
- Audiovisual association capability tests
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Grenoble
Cerebral Palsy Children, Motor Disabilities
Implementing Powered Mobility in Early Childhood Settings for Children With Cerebral Palsy
The goal of this clinical trial is to learn if a therapist training program can help providers in Part C Early Childhood Settings use powered mobility (PM) with young children who have cerebral palsy (Gross Motor Function…
- Conditions
- Cerebral Palsy Children, Motor Disabilities, Developmental Disability, Rehabilitation
- Trial name
- NCT07220590
- Testing
- Therapist Training on Powered Mobility Implementation, Powered Mobility Intervention for Child-Caregiver Dyads
- Where
- 3 sites in United States
- Volunteers
- 70 people
- Sponsor
- Oregon Health and Science University
Oncology, Survivorship
A Symptom Management Application for Children at the Early Stage of Cancer Survivorship and Their Caregivers
The goal of this randomized controlled trial is to examine the efficacy of the mHealth app in improving symptoms experienced by children in the early stage of cancer survivorship, including physical function, anxiety, depressive…
- Trial name
- NCT05748210
- Testing
- Symptom management mobile health application with personalised support, Wait-list Symptom management mobile health application with personalised support
- Where
- 2 sites in Hong Kong
- Volunteers
- 150 people
- Sponsor
- Chinese University of Hong Kong
Development and Health, Behavior and Behavior Mechanisms
The Effect of Mobile Devices on the Development and Health of Young Children
Interactive electronic devices (IEDs) have become a common part of young children's lives, yet research on this topic remains limited.
- Conditions
- Development and Health, Behavior and Behavior Mechanisms, Cognition, Physical Health
- Trial name
- iKids (NCT06810570)
- Where
- 2 sites in United Kingdom
- Volunteers
- 874 people, healthy volunteers welcome
- Sponsor
- Sheffield Hallam University
Physical Inactivity in Early Childhood and Care, Delayed Fundamental Motor Skill Development
Active Fundament - Fundamentally Better
The objective of this longitudinal, quasi-experimental study is to improve children's fundamental motor skills and physical activity levels.
- Conditions
- Physical Inactivity in Early Childhood and Care, Delayed Fundamental Motor Skill Development, Early Childhood & Care Physical Activity Behavior, Motor Development in Children Aged 2-6 Years
- Trial name
- AF (NCT07315009)
- Testing
- Actief Fundament
- Where
- 3 sites in Netherlands
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Fontys University of Applied Sciences
Epilepsy; Seizure, Child Development
Genotype, Phenotype, and Disease Progression of Developmental Epileptic Encephalopathy With Onset Before 2 Years of Age
According to estimates by the World Health Organization in 2019, more than 50 million people around the world have epilepsy. Nearly 80% of patients with epilepsy live in developing countries.
- Conditions
- Epilepsy; Seizure, Child Development, Gene Abnormality, Early Onset Disorder
- Trial name
- NCT06278428
- Where
- 2 sites in Vietnam
- Volunteers
- 50 people
- Sponsor
- Number 2 Children's Hospital, Ho Chi Minh City
Autism
Family-Centered Implementation of Parent Training for Autistic Toddlers in Early Intervention
Early Intervention (EI) systems are ill-equipped to serve the many children 12 to 36 months with early signs or a diagnosis of autism spectrum disorder (ASD).
- Trial name
- NCT07471594
- Testing
- Parent Training
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Dietary Assessment
Early Childhood Dietary Assessment Study
The goal of this crossover randomized controlled trial is to develop a proxy reporting protocol for a traditional 24-hour dietary recall (24HR) and an ecological momentary assessment (EMA) assisted 24-HR for use among children…
- Trial name
- ECDAS (NCT07227272)
- Testing
- Ecological Momentary Assessment, Traditional 24-hour dietary recall
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The University of Tennessee, Knoxville
Schizophrenia, Psychotic Disorders
Dimensional and Developmental Profiles of Psychosis in Children and Adolescents
Five collaborating sites in France will study the broad spectrum of schizophrenia in children and adolescents. Patients will be studied with diagnostic interviews, developmental histories, dimensional clinical ratings…
- Trial name
- PSYDEV (NCT04370730)
- Testing
- clinical, neuroimaging and DNA assessments
- Where
- 6 sites in France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Autism Spectrum Disorder, Autism
Pepea Pamoja: Cluster-Randomized Trial for Caregivers of Children With Autism in Kenya
Pepea Pamoja is a ten-session, group-based caregiver intervention designed to improve caregiver well-being and strengthen caregivers' ability to support communication and positive behavior in children with autism.
- Conditions
- Autism Spectrum Disorder, Autism, ASD
- Trial name
- NCT07259044
- Testing
- Professionally-facilitated groups, Peer-facilitated groups
- Where
- Kenya
- Volunteers
- 240 people
- Sponsor
- Indiana University
Autism Spectrum Disorder
Development and Evaluation of a Parent-led Intervention Module for Early Autism Spectrum Disorder (PRIME-ASD) in Odisha, India: Protocol for a Multiphase Mixed-methods Study Including an Open-label Randomised Controlled Trial
Many families of young children with autism in India wait a long time for a diagnosis and specialist therapy, and receive little structured guidance on how to help their child at home.
- Trial name
- NCT07858383
- Testing
- Behavioral: PRIME-ASD (Parent-led Intervention Module for Early Autism Spectrum Disorder), Behavioral: PRIME-ASD; Other: Treatment as usual
- Volunteers
- 188 people
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Developmental Delay, Behavioural Problem
Early Detection and Intervention in Developmental Delay / Behavioral Problems in Preschool Children - PLUSS
The PLUSS (Mental health, learning, development, collaboration around preschool children) is a collaborative project involving guardians, Jönköping County´s health care, preschools and social services.
- Conditions
- Developmental Delay, Behavioural Problem, Neurodevelopmental Delay
- Trial name
- PLUSS (NCT04815889)
- Testing
- PRIMUS parent training Group
- Where
- Sweden
- Volunteers
- 600 people
- Sponsor
- Region Jönköping County
Autism Spectrum Disorder (ASD)
Telehealth Intervention for Infants With Prodromes of ASD
Autism Spectrum Disorder (ASD) is a complex neurodevelopmental disorder characterized by social-communication and interaction deficits and restricted, repetitive patterns of interests and behavior.
- Trial name
- FIRRST (NCT06817746)
- Testing
- FIRRST, Parent Education
- Where
- 4 sites in Italy
- Volunteers
- 132 people
- Sponsor
- IRCCS Fondazione Stella Maris
Asthma, Respiratory Tract Infections
VItamin D in pregnanCy for prevenTion Of eaRlY Childhood Asthma
The overall aim of the study is to develop a nutritional preventive vitamin D supplementation strategy in pregnancy for early childhood asthma/persistent wheeze during the first three years of life as we hypothesize that…
- Conditions
- Asthma, Respiratory Tract Infections, Gastrointestinal Infection, Croup
- Trial name
- VICTORY (NCT06570889)
- Testing
- Cholecalciferol D3, Olive oil
- Where
- Denmark
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Professor Klaus Bønnelykke
ASD
Mental Imagery Therapy for Autism (MITA) - an Early Intervention Computerized Language Training Program for Children With Autism
Mental Imagery Therapy for Autism (MITA) is a highly innovative adaptive language therapy application for children with autism. MITA exercises are limitless in variations, therefore avoiding routinization.
- Trial name
- MITA-RCT (NCT07326423)
- Testing
- Mental Imagery Therapy for Autism (MITA), General executive function
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- ImagiRation, LLC
Confirmed Diagnosis of Cystic Fibrosis
Impact of Early Lung Physiology, Viral Infections and the Microbiota on the Development and Progression of Lung Disease in Children With Cystic Fibrosis
This study collects data on microbiological factors and lung function parameters (e.g. spirometry, body plethysmography, lung-MRI) to assess their interaction on the lung growth and lung development of infants and children with…
- Trial name
- SCILD (NCT04026360)
- Testing
- no intervention
- Where
- Switzerland
- Volunteers
- 500 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Healthy
Hair Biomarkers Study
Young children aged 0-4 years may be exposed to adverse childhood experiences (ACEs) and/or early life adversity (ELA), which are linked with worse physical and mental health across their lifespan.
- Trial name
- HBS-II (NCT07011082)
- Testing
- Stress preventative measures
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Stanford University