Clinical trials: Early Childhood
Micronutrient Deficiencies, Anemia
Effectiveness of Multiple Micro-nutrient Fortified Fudge on Nutritional Status of 3-5 Years of Age Children
Multiple micro-nutrient deficiencies in Pakistan is wide spread, there is dire need to address these by using smart solutions, among them multiple fortified product (fudge) is an alternate possible way to address this issue.
- Conditions
- Micronutrient Deficiencies, Anemia, Fortification, Undernutrition
- Trial name
- NCT03450174
- Testing
- Formative messgaes, Fortified product, Fortified product plus
- Where
- Pakistan
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- University of Veterinary and Animal Sciences, Lahore - Pakistan
Early Childhood Caries
Effectiveness of Dental Caries Arrest Treatment in Primary Teeth Using AgNO3 Followed by NaF Varnish
Aim: This randomised controlled trial will systematically compare the efficacy of a 25% AgNO3 solution followed by 5% NaF varnish with that of a 38% SDF solution in arresting caries teeth among preschool children when applied at…
- Trial name
- NCT02019160
- Testing
- 25% AgNO3 solution followed by 5% NaF varnish
- Where
- China
- Volunteers
- 1,070 people
- Sponsor
- The University of Hong Kong
Dental Caries
Prevention Management Model for Early Childhood Caries (MAYA Project)
The purpose of this study is to determine whether dental disease patterns and transmissable bacteria that are known to cause a severe form of dental decay in young children can be reduced or eliminated by treating mothers and…
- Trial name
- NCT00066950
- Testing
- Chlorhexidine gluconate, Fluoride Varnish
- Where
- United States
- Volunteers
- 361 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Fundamental Motor Skills, Physical Activity
A Movement and Music Programme in Early Childhood Education and Care (The MoviMusi Study Protocol)
The early childhood education and care (ECEC) environment is an important setting for providing children with daily opportunities for movement and music, supporting holistic child development in the early years.
- Conditions
- Fundamental Motor Skills, Physical Activity, Music Intervention
- Trial name
- MOVIMUSI (NCT06381687)
- Testing
- A multi-component, multi-level programme (MoviMusi)
- Where
- Spain
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Conduct Disorder, ADHD
Intervening Early With Neglected Children
This study will assess early and middle childhood outcomes of an intervention for neglecting parents that was implemented in the children's infancy.
- Conditions
- Conduct Disorder, ADHD, Depression
- Trial name
- NCT02093052
- Testing
- Attachment and Biobehavioral Catch-up, Developmental Education for Families
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- University of Delaware
Pediatric Sleep Problems, Sleep Hygiene
Storybook App vs Cognitive Behavioral Therapy for Child Sleep and Attachment
This completed randomized controlled trial compared two caregiver-delivered interventions for sleep in young children: a multimodal mobile health intervention delivered through the Storybook mobile application and a face-to-face…
- Conditions
- Pediatric Sleep Problems, Sleep Hygiene, Parent-Child Attachment
- Trial name
- STORYBOOK-RCT (NCT07668609)
- Testing
- CBT-Based Psychoeducational Intervention, Storybook Mobile Application Intervention
- Where
- Ecuador
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad Católica de Cuenca
Influenza
From Innovation to Solutions: Childhood Influenza Vaccination Planning
The purpose of this study is to increase childhood influenza vaccination rates using the FDA licensed influenza vaccines according to national guidelines in a randomized cluster trial in which primary care offices are randomized…
- Trial name
- NCT01664793
- Testing
- 4 Pillars Immunization Toolkit
- Where
- United States
- Volunteers
- 87,665 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Rare Genetic Disorders, Quality of Life
The Relationship Between Functional Independence and Family Well-being in Children With Rare Genetic Disorders
This study aims to examine the psychological status and quality of life of families with children who have rare genetic disorders.
- Conditions
- Rare Genetic Disorders, Quality of Life, Functional Impairment
- Trial name
- NCT07348926
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Early Childhood Caries, Knowledge, Attitudes, Practice
Effectiveness of Strengthened Anticipatory Guidance Used in the MOH Malaysia Infant Oral Health Care Programme
This study aimed to assess the effectiveness of strengthened anticipatory guidance (AG) used in MOH Malaysia Infant Oral Healthcare Programme in preventing early childhood caries (ECC) lesions and improving caries risk of infants…
- Trial name
- MOH (NCT06000293)
- Testing
- Oral health education
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Moderate and Severe Undernutrition
Transition to Scale of Nutrition and Psychosocial Stimulation Program for Malnourished Children
We hypothesize that it is feasible to integrate a program of Nutritional Care and Pychosocial Stimulation into the Community Clinics in Bangladesh and thereby improve malnourished children's growth and development after a year of…
- Trial name
- TTS Bangladesh (NCT02208531)
- Testing
- Psychosocial Stimulation and Nutritional Care
- Where
- Bangladesh
- Volunteers
- 6,400 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Hepatitis B
Adolescents' Response to Hepatitis B Vaccine Booster Dose
The aims of this study are to determine: 1. the degree of immunity against hepatitis B, 2. factors associated with immunity against hepatitis B, 3.
- Trial name
- REACH (NCT01341275)
- Testing
- hepatitis B vaccine
- Where
- 2 sites in United States
- Volunteers
- 400 people
- Sponsor
- Baylor College of Medicine
Early Childhood Caries
Salivary Interleukin-32, Interleukin-10, Interleukin-6 and Tumor Necrosis Factor-alpha Levels in Children
This study aimed to evaluate the levels of interleukin 10, interleukin 6, interleukin 32 and tumor necrosis factor-alpha (TNF-α) in saliva of children with early childhood caries.
- Trial name
- NCT04958005
- Testing
- ELISA
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Aydin Adnan Menderes University
Early Child Development and Growth
The Pakistan Early Childhood Development Scale Up Trial
The purpose of this study is to evaluate whether the integration of an early child 'stimulation and care for development' intervention, either alone or in combination with an 'enhanced care for nutrition' intervention, delivered…
- Trial name
- PEDS (NCT00715936)
- Testing
- Control, ECD, Enhanced Nutrition
- Where
- Pakistan
- Volunteers
- 1,489 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Early Life Adversity, Caregiver Stress
The Resilience Clinic Evaluation
Early life adversity can affect children's physical and mental health. The Resilience Clinic is a support program for young children and their caregivers who have been exposed to significant adversity, aiming to prevent the…
- Trial name
- NCT05690256
- Testing
- Resilience Clinic, Enhanced primary care
- Where
- 4 sites in United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Dental Caries in Children
Salivary Antioxidant Capacity Before and After Complete Dental Rehabilitation
Salivary samples were obtained from 20 children in their fifth year of life diagnosed S-ECC and 20 age and sex matched controls.
- Trial name
- NCT03432728
- Testing
- Dental rehabilitation under general anesthesia
- Where
- Saudi Arabia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riyadh Colleges of Dentistry and Pharmacy
Diet Habit, Cognitive Function
Diet Quality and Cognitive Control Function in Early Childhood: A Pilot Study
This study aims to study the relationship between diet and cognitive function among 4-5-year-olds.
- Trial name
- NCT03313245
- Testing
- No Intervention/Observational Study
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- University of Illinois at Urbana-Champaign
Early Melanoma, Advanced Melanoma
Impact of Anti PD-1 Therapy in Children, Adolescents and Young Adults (CAYA) Melanoma Patients
This is a retrospective observational cohort study, the primary objective is investigate the activity and efficacy of anti PD-1 antibodies in children, adolescents and young adult melanoma patients, with radically resected or…
- Trial name
- MELCAYA (NCT06281912)
- Where
- 13 sites in France, Germany and 5 more
- Volunteers
- 70 people
- Sponsor
- Azienda Ospedaliera di Perugia
School Readiness, Executive Function (Cognition)
Playful Physical Activity for Executive Functions and School Readiness in Preschool Children
Executive functions, such as attention, inhibition, working memory, and planning, are important for early learning and school readiness in preschool children.
- Conditions
- School Readiness, Executive Function (Cognition), Preschool Child Development
- Trial name
- PPA-EF-SR (NCT07678294)
- Testing
- Playful Physical Activities Intervention, Regular Physical Education Curriculum
- Where
- Tunisia
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Inonu University
Early Childhood Caries (ECC), Oral Health Behavior Change
Oral Health Awareness Among Egyptian Population
The objective of this research is to investigate the effect of digital tele-dentistry application using AI-generated content on the awareness and performance among a sample of Egyptian children and their caregivers in both…
- Trial name
- NCT07248800
- Where
- Egypt
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Cairo University
Sickle Cell Disease, Cognitive Ability, General
Improving Parental Psychosocial Functioning and Early Developmental Outcomes in Children With Sickle Cell Disease
There are all significant risk factors for poor early cognitive development and, as such, neurocognitive deficits have been demonstrated in pre-school children with sickle cell disease (SCD).
- Conditions
- Sickle Cell Disease, Cognitive Ability, General, Psychological Stress, Parenting
- Trial name
- NCT02394899
- Testing
- Play therapy, Problem solving skills
- Where
- Jamaica
- Volunteers
- 64 people
- Sponsor
- The University of The West Indies