Clinical trials: Early Childhood
Down Syndrome
Promoting Health Through Parent Empowerment and the Activation of Routines (PrO-PEAR)
This study will examine the feasibility of the Promoting Health through Parent Empowerment and the Activation of Routines (Pro-PEAR) intervention using a open case-series for intervention optimization followed by a pilot RCT in…
- Trial name
- Pro-PEAR (NCT05020366)
- Testing
- Promoting Health through Parent Empowerment and the Activation of Routines, Enhanced Usual Care
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Pittsburgh
Plasmodium Vivax Malaria
Papua New Guinean Duffy Negativity And Vivax Malar
The purpose of this study is to learn more about vivax malaria in very young children, how the growth of children is affected by malaria infections, and how inherited traits protect children from getting malaria.
- Trial name
- NCT00138489
- Where
- Papua New Guinea
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Healthy Lifestyle
Active Kindergarten - Active Children
The AK-AC study was designed as a two-arm, randomised by ECEC institution, evaluative controlled trial with the overarching aim of increasing the children's PA level and reduce sedentary time.
- Trial name
- AK-AC (NCT04555746)
- Testing
- Physical activity
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of South-Eastern Norway
Cystic Fibrosis, Children
Prevention of CF Exacerbation in Childhood: PREVEC Study
Pulmonary exacerbations of CF are an important cause for the experienced disability of patients, respiratory symptoms, and decreases in lungfunction, which require antibiotic therapy at home or in the hospital.
- Conditions
- Cystic Fibrosis, Children, Exhaled Breath Condensate, Non-invasive Inflammatory Markers
- Trial name
- PREVEC (NCT01241890)
- Where
- 3 sites in Netherlands
- Volunteers
- 49 people
- Sponsor
- Maastricht University Medical Center
Candida Infection, Oral Thrush
Oropharyngeal Candidiasis (OPC) and S-ECC
The overall objective of this study is to investigate the association of early Candida infection (known as oral thrush or oropharyngeal candidiasis, OPC) in children during the first year of life with the onset and severity of…
- Conditions
- Candida Infection, Oral Thrush, Early Childhood Caries
- Trial name
- Oral-Thrush (NCT05761197)
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Temple University
Early Childhood Dental Caries
Development and Dissemination of Oral Health Risk Assessment and Referral Guidelines
Purpose: 1. Revise the existing oral health risk assessment tool (known as the Encounter Form in the IRB-approved project DENT-1527) and develop accompanying guidelines for its use and distribution. 2.
- Trial name
- PORRT (NCT00596856)
- Testing
- Development and dissemination of priority oral health risk assessment and referral guidelines - PORRT
- Sponsor
- University of North Carolina, Chapel Hill
Physical Activity
Training Early Childhood Educators to Increase Children's Physical Activity: The TEACH-Preschooler Study
This study aims to determine the effect of delivering a physical activity e-learning course to early childhood educators on young children's physical activity and sedentary behaviour while at childcare.
- Trial name
- NCT05359536
- Testing
- Training Early Childhood educators in PA
- Where
- Canada
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Feeding Disorder of Infancy or Early Childhood
Examining Relationships Between Family Mealtime and Feeding Outcomes in Young Children With Sensory Food Aversions
This study will examine the feasibility and preliminary effects of the Mealtime PREP (Promoting Routines of Exploration and Play) intervention package for young children with Sensory Food Aversions and their parents.
- Trial name
- NCT03138551
- Testing
- Mealtime PREP (Promoting Routines of Exploration and Play)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Pittsburgh
Language Development, Behavior, Child
Literacy Promotion for Latinos Study
This study tests the extent to which tailored outreach text messages that provide a cue to action and an intervention that enhances access to poverty-reducing resources, in combination with standard primary care literacy…
- Conditions
- Language Development, Behavior, Child, Parenting, Literacy
- Trial name
- NCT04609553
- Testing
- Usual care including ROR, Text messages, Connection to community resources
- Where
- United States
- Volunteers
- 662 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Early Chilhood Trauma, Personality Disorder
Sensorimotor Psychotherapy for Personality Disorders
SUMMARY Rationale: Personality disorders are treated conform the Dutch GGZ-zorgstandaard mainly with verbal psychotherapies but experts by experience call out to make use of body-oriented approaches as well.
- Trial name
- SPiPS (NCT07342270)
- Testing
- Sensorimotor Psychotherapy, Treatment as ususal
- Where
- 6 sites in Netherlands
- Volunteers
- 131 people
- Sponsor
- Tilburg University
Dental Caries in Children
Social Impact of Children's Dental Appearance
This study evaluates the social impact of children's dental perception from children with or without caries experience. For this, children and their parents are shown pictures of child faces with healthy teeth, decayed teeth and…
- Trial name
- NCT03800043
- Where
- Germany
- Volunteers
- 180 people
- Sponsor
- University of Göttingen
Eczema, Allergy
LaCE (Lactobacillus Paracasei LPB27 On Early Childhood Eczema)
The LaCE study is a double-blind, randomised, placebo-controlled trial examining the effectiveness of the probiotic Lactobacillus paracasei LPB27 in treating eczema in young children.
- Trial name
- NCT06584552
- Testing
- Lactobacillus Paracasei LPB27, Maltodextrin
- Where
- Australia
- Volunteers
- 100 people
- Sponsor
- The University of New South Wales
Neonatal Death, Mental Competency
Survive and Thrive Boa Vista Early Childhood Program
The proposed project will tackle the two most salient problems for children under 5 in Brazil: the continued high rates of neonatal mortality, and the large disparities in early childhood development.
- Trial name
- STBV (NCT03386747)
- Testing
- Home visits to improve parenting behaviors, Center based parenting groups
- Where
- Brazil
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Swallowing Disorder, Perinatal Asphyxia
Effect of Non-nutritive Sucking on Transition to Oral Feeding in Infants With Asphyxia
The transition period to full oral feeding in infants with perinatal asphyxia is important in predicting long-term outcomes. The transition to independent oral feeding is accepted as a discharge criterion by the American Academy…
- Conditions
- Swallowing Disorder, Perinatal Asphyxia, Feeding; Difficult, Newborn, Feeding Disorder of Infancy or Early Childhood
- Trial name
- NCT05687708
- Testing
- Non-Nutritive Sucking
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medipol University
Developmental Disabilities, Developmental Delay
Exploratory Trial of a Pediatric Web-Based Care Planning Guide
Infants and toddlers with developmental disabilities or delays use early intervention (EI) for rehabilitation services. Yet, poor quality of EI services is pervasive, particularly for racially and ethnically diverse and socially…
- Trial name
- PROSPECT+ (NCT06458959)
- Testing
- PEM+
- Where
- United States
- Volunteers
- 223 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Autism Spectrum Disorder (ASD)
Associations of Autistic Traits and Feeding Difficulties
The objective is to assess the prevalence of autistic traits and feeding disorders in the general population.
- Trial name
- BAMBI2025 (NCT07188870)
- Where
- Hungary
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Dental Caries
Preventing Early Childhood Caries With Silver Diamine Fluoride
Background: Silver diamine fluoride (SDF) solution is effective in arresting early childhood caries (ECC). Previous studies suggested that it might exert a preventive effect in managing ECC.
- Trial name
- NCT04075474
- Testing
- silver diamine fluoride, sodium fluoride
- Where
- Hong Kong
- Volunteers
- 730 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Childhood Obesity, Evidence-Based Practice
Network-Based Support to Help Community Coalition Members Choose and Use Strategies to Improve Child Health
Community coalitions bring together residents and organizations to improve child health, but they may need support to identify and put research-supported strategies into practice.
- Conditions
- Childhood Obesity, Evidence-Based Practice, Food Systems, Food Policy
- Trial name
- NCT07804550
- Testing
- Catalyzing Communities, FICAS Implementation Intervention
- Where
- United States
- Volunteers
- 3,300 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Reading Disability
Executive Function in Early Childhood
Despite the fact that a substantial number of school age children struggle with both reading and math acquisition, the brain mechanisms of the overlapping aspects of reading and math skills, thought in part to be linked via…
- Trial name
- NCT03713125
- Testing
- Reading Tutoring
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Healthy Diet, Stress
Happy Family, Healthy Kids Program
Happy Family, Healthy Kids program, funded by the Michigan Health Endowment Fund, is a 14-week healthy eating program aimed to foster "Happy Family \& Healthy Kids." The program will target parental emotional eating through a…
- Conditions
- Healthy Diet, Stress, Pediatric Obesity, Intergenerational Relations
- Trial name
- NCT04183179
- Testing
- Happy Family, Healthy Kids Program
- Where
- United States
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Michigan State University