Clinical trials: Early Childhood Caries
Early Childhood Caries
Investigation of Supragingival Plaque Microbiome in Early Childhood Caries
The purpose of this study was to characterize the supragingival plaque microbiome in children with early childhood caries and identify potential microorganisms associated with caries.
- Trial name
- NCT04456335
- Testing
- Collection of supragingival plaque from caries free children
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Trakya University
Caries, Dental, Health Behavior
Interactive Parent-Targeted Text Messaging in Pediatric Clinics to Reduce Caries Among Urban Children
This is a randomized clinical trial to test the efficacy of a parent-targeted text message-based intervention program on caries incidence and oral health behaviors (child and parent).
- Trial name
- iSmile (NCT03294590)
- Testing
- OHT Parent targeted text messages, CWT Parent targeted text messages
- Where
- United States
- Volunteers
- 754 people, healthy volunteers welcome
- Sponsor
- Boston University
Caries,Dental
Fluoride Caries-control Effectiveness/Feasibility in Children
The aim of this study is to compare the effectiveness and feasibility of using silver diamine fluoride solution (SDF) vs. sodium fluoride varnish (NaF) for caries management in children from Bogotá (and its suburban areas) and…
- Trial name
- NCT06690008
- Testing
- Experimental group
- Where
- 2 sites in Colombia
- Volunteers
- 814 people, healthy volunteers welcome
- Sponsor
- Universidad El Bosque, Bogotá
Dental Caries in Children
Social Impact of Children's Dental Appearance
This study evaluates the social impact of children's dental perception from children with or without caries experience. For this, children and their parents are shown pictures of child faces with healthy teeth, decayed teeth and…
- Trial name
- NCT03800043
- Where
- Germany
- Volunteers
- 180 people
- Sponsor
- University of Göttingen
Dental Caries
Evaluation of a Brief Tailored Motivational Intervention to Prevent Early Childhood Caries
The Detroit Dental Health Project (DDHP)aims to promote oral health and reduce disparities within the community of low-income African-American children (0-5 years) and their main caregivers (14+ years), living in the City of…
- Trial name
- NCT01123330
- Testing
- Motivational Interviewing
- Where
- United States
- Volunteers
- 2,042 people, healthy volunteers welcome
- Sponsor
- Temple University
Early Childhood Caries, Dental Caries in Children
Treatment of Early Childhood Caries Using Silver Diammine Fluoride and Sodium Fluoride Tricalciumphosphate and the Effects on Oral Health Related Quality of Life
There is still a need for the assessment of different minimal intervention strategies and treatments focusing on the prevention and arrest of carious lesions of primary molars The evidence-based clinical practice guideline on…
- Conditions
- Early Childhood Caries, Dental Caries in Children, Dental Caries Extending Into Dentin, Dental Caries
- Trial name
- NCT05772039
- Testing
- Topical application of 38% Silver Diammine Fluoride Solution, Topical application of 5% Sodium Fluoride with functional Tricalcium phosphate Varnish
- Where
- Pakistan
- Volunteers
- 72 people
- Sponsor
- Universiti Sains Malaysia
Early Childhood Caries
Effectiveness Fluoride Varnishes in Children With Early Childhood Caries
The study was carried out in 88 children with severe early childhood caries (dmfs≥age +1) who were referred to the investigators' clinic.
- Trial name
- NCT03625310
- Testing
- Sodium Fluoride, Sodium Fluoride with TCP, Sodium Fluoride with CXP
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Merve Erkmen Almaz
Early Childhood Caries (ECC)
Analysis of Salivary Proteins in Young Children as an Device to Improve Caries Risk Assessment
The goal of this observational study is to learn if the composition of salivary proteins in 3-year-old children, from communities with documented varying caries risks, can be used to identify future diagnostic predictors for…
- Trial name
- DecodECC (NCT06957509)
- Where
- Sweden
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Dental Caries
Effectiveness of Fluoride Varnish in the Prevention of Early Childhood Caries: A Randomized Controlled Trial
Triple-blind randomized controlled trial with two parallel arms conducted between 2012 and 2014. Children 2-3 years old, from 28 rural public preschools, located in low socioeconomic areas of Chile were invited to participate.
- Trial name
- NCT02742038
- Testing
- Fluoride varnish plus education
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Universidad de La Frontera
Tooth Decay
Efficacy Trial of MySmileBuddy
This study seeks to evaluate the best way to encourage a healthy diet and proper fluoride use in children at greatest risk for tooth decay.
- Trial name
- NCT04845594
- Testing
- MySmileBuddy (MSB)
- Sponsor
- Columbia University
Dental Caries
Perception of Children With Visible Untreated and Treated Caries
In Germany about 5 to 20% of children suffer from early childhood caries (ECC). Preceding results of eye-tracking-studies on the perception of patients with unilateral cleft and patients with severe orthognathic malocclusion let…
- Trial name
- ECC-ET (NCT02899273)
- Where
- 2 sites in Germany
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Göttingen
Early Childhood Caries
Salivary Cystatin S Levels in a Group of Egyptian Children
Aim of the study 1. Measuring the levels of salivary cystatin S protein and salivary buffering capacity to determine their relation to early childhood caries. 2.
- Trial name
- NCT05716867
- Testing
- Measurement of salivary cystatin S protein levels in saliva
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Early Childhood Caries (ECC), Active Dentin Caries in Primary Molars
Efficacy of Silver Diamine Fluoride Versus Nano-Silver Fluoride in Arresting Active Dentin Caries in Primary Teeth in Young Children
Early childhood caries is a major public health problem affecting preschool children worldwide. Silver Diamine Fluoride is a well-established non-invasive treatment for arresting caries; however, it causes black discoloration of…
- Trial name
- NCT07382245
- Testing
- Nano-Silver Fluoride, Silver Diamine Fluoride
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- October University for Modern Sciences and Arts
Reversible Pulpitis, Pulpitis
Antibacterial Effect and Clinical Performance of Chitosan Modified Glass Ionomer
The study is a randomized clinical trial that assesses the clinical success and the antibacterial effect on carious dentine of glass ionomer when modified with Chitosan and/or Titanium dioxide nano particles vs the control group…
- Conditions
- Reversible Pulpitis, Pulpitis, Caries,Dental, Caries Class I
- Trial name
- NCT04365270
- Testing
- Glass Ionomer, Chitosan Low Molecular Weight (20-200 Mpa.S), Chlorhexidine Diacetate
- Where
- Egypt
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Early Childhood Caries, Health Care Acceptability
Effectiveness and Acceptability of SDF Compared to ART for the Management of Early Childhood Caries
The goal of this clinical trial is to assess the acceptability and clinical effectiveness of Silver Diamine Fluoride (SDF) in comparison with Atraumatic Restorative Treatment (ART) in Early Childhood Caries (ECC) management at…
- Trial name
- SDF and ART (NCT06786975)
- Testing
- Silver Diamine Fluoride, Atraumatic Restorative Treatment
- Where
- Chile
- Volunteers
- 156 people
- Sponsor
- Universidad de La Frontera
Early Childhood Caries
Knowledge and Behavior Toward Early Childhood Caries
400 mothers are at least 18 years of age who have at least a child with minimum age of 6 years or even younger will be selected from the outpatient clinics of October University for Modern Sciences and arts (MSA).
- Trial name
- NCT03693443
- Testing
- early childhood caries
- Where
- Egypt
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- October University for Modern Sciences and Arts
Early Childhood Caries
Parental Acceptance and Perception of Silver Diamine FlouridApplication Among A Sample of Egyptian Children.
Dental caries can be prevented or arrested . Moreover, preventive measures for dental caries are more cost effective than emergency room visits or restorative treatments when the illness has been established .
- Trial name
- NCT04218955
- Testing
- Silver Diamine Flouride
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Cairo University
Severe Early Childhood Caries, Caries
Construction of a Multidimensional Risk Prediction Model for Severe Early Childhood Caries
This study aims to address the high prevalence and recurrence rate of severe early childhood caries (S-ECC) by breaking away from the traditional single biological factor perspective and introducing the theories of "24-hour…
- Trial name
- NCT07335744
- Testing
- questionnaire survey
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- The Children's Hospital of Zhejiang University School of Medicine
Early Childhood Caries
Clinical Efficiency and Treatment Failure of Hall Versus SDF Techniques in the Management of Carious Primary Molar.
This study will compare two non- invasive treatment options: Hall technique and 38% Silver diamine fluoride. Both are methods used to create a more favorable environment without removal of caries leading to the arrest of the…
- Trial name
- NCT04765904
- Testing
- SDF, Hall technique
- Volunteers
- 120 people
- Sponsor
- Cairo University
Early Childhood Caries
Effect of Three Types of Fluoride Varnish in Preventing Early Childhood Caries
This study evaluates and compares the effect of two types of calcium- and phosphate-containing fluoride varnishes to conventional fluoride varnishes in preventing early childhood caries.
- Trial name
- NCT04274569
- Testing
- NaF vanish, NaF-TCP, NaF-CPP-ACP
- Where
- Hong Kong
- Volunteers
- 570 people
- Sponsor
- The University of Hong Kong