Clinical trials: Early Interventions
Prematurity
Different Intervention Models of Premature Infants Based on the ICF Biopsychosocial Model
Prematurity is an important risk factor for delayed neuropsychomotor development. The main objective of this study is to analyze the impact of different intervention models on the neuropsychomotor development of premature babies…
- Trial name
- NCT05989438
- Testing
- Orientations for families, Professional stimulation more orientations for families.
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Federal University of Health Science of Porto Alegre
Eating Disorders
Study of the Effectiveness of a Systematic Minimal Early Intervention on Care Engagement in Adults With Eating Disorders Requesting Specialized Treatment.
Eating disorders (EDs) are complex psychiatric conditions-such as anorexia nervosa and bulimia nervosa-often emerging in young adulthood and associated with high morbidity and mortality.
- Trial name
- AGIS-TCA (NCT07411807)
- Testing
- Program (Systematic Minimal Early Intervention for Eating Disorders)
- Where
- France
- Volunteers
- 215 people
- Sponsor
- Centre Hospitalier St Anne
Psychotic Disorders, Schizophrenia
Graduated Recovery Intervention Program for Enhancing Treatment for First-Episode Psychosis
This study will determine the effectiveness of the Graduated Recovery Intervention Program, a manual-based individual therapy program, in enhancing the clinical benefit of routine treatment for individuals recovering from their…
- Trial name
- NCT00307216
- Testing
- Graduated Recovery Intervention Program (GRIP), Treatment as usual (TAU)
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of North Carolina, Chapel Hill
Autism Spectrum Disorder
Leveraging Autism Intervention for Families Using Telehealth (LIFT)
The purpose of the LIFT study is to develop a technology-assisted adaptation of the JASPER (Joint Attention, Symbolic Play, Engagement, and Regulation: Kasari et al., 2021) social communication intervention for young children…
- Trial name
- LIFT (NCT05582655)
- Testing
- ONLINE, COACH
- Volunteers
- 80 people
- Sponsor
- University of Oregon
Diabetic Non-proliferative Retinopathy, Type2 Diabetes
Clinical Study of Tang Wang Prescription Intervene Diabetic Non-proliferative Retinopathy
This study include 384 Participants with diabetic non-proliferative retinopathy Design Method: Randomized, double blind, placebo controlled and multicenter clinical study.
- Trial name
- NCT03025399
- Testing
- Tangwang prescription
- Volunteers
- 384 people
- Sponsor
- Fengmei Lian
Asthma
A Study of Efficacy and Safety of Depemokimab Compared With Placebo in Adults and Adolescents With at Risk Type 2 Asthma
The aim of this study is to evaluate the efficacy of depemokimab administered as an adjunctive therapy, in participants with Type 2 asthma at risk of exacerbations compared to the guideline recommended standard of care (SoC).
- Trial name
- MODIFY (NCT07456033)
- Testing
- Depemokimab
- Where
- 17 sites in United States, United Kingdom
- Volunteers
- 456 people
- Sponsor
- GlaxoSmithKline
Child Behavior, Parent-Child Relations
The Supporting Early Learning Study
FIND (Filming Interactions to Nurture Development) is a potentially disruptive innovation in the field of early childhood intervention.
- Trial name
- SEAL (NCT04107506)
- Testing
- Filming Interactions to Nurture Development, The Healthy Toddler Program
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Pregnancy
Effectiveness of Online-Based "Pregnant Women Care Cadres" Intervention on Husband Support in Early Detection of High Risk in Medan Maimun Area
The goal of this quasi-experimental study is to evaluate whether an online-based "Caring for Pregnant Women" intervention delivered through community health cadres can improve husband support in the early detection of high-risk…
- Trial name
- NCT07430033
- Testing
- Online-Based "Caring for Pregnant Women" Intervention Through Community Health Cadres to Enhance Husband Support in Early Detection of High-Risk Pregnancy
- Where
- Indonesia
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Siti Saidah Nasution
Lung Cancer, Mesothelioma
Feasibility of an Early Palliative Care Intervention for Metastatic Cancer Patients. A Phase 2 Study.
The objective of this phase 2 study is to evaluate the feasibility of an early palliative care intervention for metastatic cancer patients.
- Conditions
- Lung Cancer, Mesothelioma, Pancreas Cancer, Gastric Cancer
- Trial name
- NCT02078700
- Testing
- The early palliative care programme
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Spinal Cord Injuries, Cognitive Dysfunction
Early Intervention for Information Processing Speed Deficits in Acute SCI: A Pilot Study
This study seeks to conduct a pilot study to test whether a cognitive training program can improve processing speed abilities in individuals with acute traumatic spinal cord injury.
- Conditions
- Spinal Cord Injuries, Cognitive Dysfunction, Cognitive Impairment, Acute Spinal Cord Injury
- Trial name
- SCI-IQ (NCT06452264)
- Testing
- game-like computerized activities
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Kessler Foundation
COVID-19
The Standard of Care Combined With Glucocorticoid in Elderly People With Mild or Moderate COVID-19
This study is aimed to explore the dual-dimensional early intervention strategy of standard of care combined with host immunomodulation in elderly patients with mild and moderate COVID-19.
- Trial name
- NCT05855395
- Testing
- Glucocorticoid
- Where
- 15 sites in China
- Volunteers
- 5,815 people
- Sponsor
- Huashan Hospital
Colorectal Neoplasms, Colonic Neoplasms
Facilitating Risk-Appropriate Colorectal Cancer Testing - Testing the Cancer Risk Intake System (CRIS)
This study will adapt and test a touch-screen computer program to evaluate cancer risk and provide patient-tailored recommendations for appropriate risk-based testing.
- Trial name
- NCT02368236
- Testing
- Tailored Printout
- Volunteers
- 1,012 people
- Sponsor
- University of Texas Southwestern Medical Center
Upper Extremity Dysfunction
Movement Enhancing Device for Children
The purpose of this study is to assess: 1) how infants move their bodies to explore, play, and solve problems, 2) if this is different in a high-risk group of infants, and 3) if these abilities can be advanced in a high-risk…
- Trial name
- NCT01959581
- Testing
- Movement Enhancing Device
- Where
- 3 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Opioid-use Disorder, Substance Use Disorders
Promoting Caregiver-child Attachment and Recovery Through Early Intervention (pCARE): A Pilot Randomized Control Trial
This purpose of this study is to use the existing infrastructure and therapeutic relationships developed by Early Intervention, a national system of child development programs, to make an evidence-based intervention for parents…
- Conditions
- Opioid-use Disorder, Substance Use Disorders, Parenting
- Trial name
- pCARE (NCT04675099)
- Testing
- pCARE, Standard Early Intervention services
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Baystate Medical Center
Cardiovascular Diseases, Respiratory Diseases
Study on Intervention Effect of Heat-related Health Risk Early Warning Digital Technology for School-age Children
This cluster randomized trial is conducted in Beijing primary schools to evaluate the efficacy of a WeChat mini-program-based high-temperature early warning intervention on the physical and cognitive health of school-age…
- Conditions
- Cardiovascular Diseases, Respiratory Diseases, Mental Health Disorders, Heat Illness
- Trial name
- NCT07643571
- Testing
- WeChat Mini-program Based Heat Health Risk Early Warning Intervention
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention, China
Preterm, Sensory Disorders
Evaluation of The Effectiveness of The SAFE Early Intervention Program
In this study, it was aimed to examine the effect of SAFE, which is a sensory-based, activity-oriented early intervention approach applied in an enriched environment with family cooperation, on cognitive, language, motor and…
- Conditions
- Preterm, Sensory Disorders, Cerebral Palsy
- Trial name
- NCT06930482
- Testing
- Safe early intervention, early intervention approach based on neurodevelopmental treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Gazi University
Prostate Cancer, Psychosocial Effects of Cancer and Its Treatment
Communication and Intimacy-Enhancing Therapy for Men With Early Stage Prostate Cancer and Their Partners
RATIONALE: Participating in a therapy program may enhance communication and intimacy between men with prostate cancer and their partners.
- Conditions
- Prostate Cancer, Psychosocial Effects of Cancer and Its Treatment, Sexual Dysfunction and Infertility, Sexuality and Reproductive Issues
- Trial name
- NCT00503646
- Testing
- communication intervention, counseling intervention, questionnaire administration
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Age-related Macular Degeneration (AMD)
Intervention Trial in Early Age-related Macular Degeneration
The purpose of the I-TEAM project is to assess whether there is a change in visual function and status of the retina after a year of intervention in subjects with early signs of Age-related Macular Degeneration.
- Trial name
- I-TEAM (NCT01694680)
- Testing
- Lutein-enriched-egg beverage (NWT-02)
- Where
- 4 sites in United States, Germany and 2 more
- Volunteers
- 120 people
- Sponsor
- Newtricious R&D BV
Dementia, Cognitive Impairment
A Technology-Driven Intervention to Improve Early Detection and Management of Cognitive Impairment
Most experts advocate for early detection of cognitive impairment (CI) so that patients and caregivers can be prepared for making difficult decisions and to improve quality of life, but studies show that screening alone isn't…
- Trial name
- CI Wizard (NCT05723523)
- Testing
- CI-CDS
- Where
- 2 sites in United States
- Volunteers
- 3,230 people
- Sponsor
- HealthPartners Institute
Early Intervention, Child of Impaired Parents
VIA Family - Family Based Early Intervention Versus Treatment as Usual
This RCT aims to investigate the effect of an early family-based intervention (VIA Family) focusing on reducing risk and increasing resilience for children in families where at least one parent has a severe mental illness.The…
- Conditions
- Early Intervention, Child of Impaired Parents, Child, Adolescent
- Trial name
- NCT03497663
- Testing
- VIA Family intervention, Treatment As Usual
- Where
- Denmark
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital