Clinical trials: Early Onset Preeclampsia
Preeclampsia (PE), Intrauterine Growth Restriction (IUGR)
Statin Intervention for Severe Early-Onset Placental Insufficiency. (STATIN-PRE Trial)
In pregnancies with placental insufficiency, the only available treatment is close monitoring to determine the point at which the risks of preterm birth for the baby are lower than the risks of continuing the pregnancy.
- Conditions
- Preeclampsia (PE), Intrauterine Growth Restriction (IUGR), Placental Insufficiency
- Trial name
- STATIN-PRE (NCT07098975)
- Testing
- Pravastatin 40 mg
- Where
- 2 sites in Spain
- Volunteers
- 154 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Pre-Eclampsia, Hippocampus
Fetal Fornix and Hippocampus in Pregnant Women With Early-Onset Preeclampsia
Since early-onset preeclampsia (EOPE) is commonly associated with inadequate placentation, placental insufficiency, chronic fetal hypoxia, oxidative stress, and heightened inflammation, these pathological processes may adversely…
- Trial name
- FHC-EOPE (NCT07245056)
- Testing
- FHC dimensions in EOPE and control groups
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Ankara Etlik City Hospital
Preeclampsia
Esomeprazole in Treatment of Early Onset Preeclampsia (ESOPE Trial)
Pre-eclampsia is one of the most serious complications of pregnancy affecting 3-8 % of pregnancies worldwide. It is a multi-system disorder involving maternal vessels (causing hypertension and endothelial dysfunction), the…
- Trial name
- NCT03213639
- Testing
- Esomeprazole 40 mg Oral Tablet
- Where
- Egypt
- Volunteers
- 205 people
- Sponsor
- Assiut University
Pregnancy
Detecting Early Onset Pre-eclampsia and Use of Placental Growth Factor (PlGF) for Marker of Trisomy 21
This is a study for the evaluation of the benefits of 1 st Trimester risk markers in detecting Early Onset Pre-eclampsia and the use of the Placental Growth factor(PIGF) as a potential marker for Trisomy 21 and other…
- Trial name
- PlGF (NCT01387776)
- Where
- Canada
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- Clinique Ovo
Preeclampsia
Esomeprazole With Sildenafil Citrate in Women With Early-onset Preeclampsia
Previous studies have shown that expectant management of preeclampsia in the context of extreme prematurity may improve perinatal outcomes.
- Trial name
- NCT03724838
- Testing
- Esomeprazole with Sildenafil Citrate, Sildenafil Citrate
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Aswan University Hospital