Clinical trials: Edema, Pulmonary
Preeclampsia, Pulmonary Edema
Point-of-care Ultrasound Abnormalities in Early Onset Preeclampsia
The study is planned to describe the prevalence and severity of cardiac, lung and optic-nerve sheath diameter (ONSD) ultrasound abnormalities in women with early onset preeclampsia with severe features.
- Conditions
- Preeclampsia, Pulmonary Edema, Cardiac Function
- Trial name
- NCT05662995
- Testing
- Lung ultrasound
- Where
- South Africa
- Volunteers
- 60 people
- Sponsor
- University of Cape Town
Acute Mountain Sickness, Subclinical High Altitude Pulmonary Edema
The Incidence of Subclinical High-altitude Pulmonary Oedema at High Altitude
The aim of this investigation is to determine the incidence of silent interstitial pulmonary edema by chest ultrasound at moderate altitude (3905m).
- Trial name
- NCT01794130
- Where
- Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Institute of Mountain Emergency Medicine
Cardiopulmonary Disease, Fluid Overload
Fluid Status and Body Composition Analysis by Bioelectrical Impedance in Patients After Cardiac Surgery (FLUBIACS)
Evaluation of fluid status in cardiac surgery patients using bioelectrical impedance and its impact on postoperative morbidity and mortality
- Trial name
- FLUBIACS (NCT06498375)
- Testing
- Bioelectrical impedance
- Where
- Slovenia
- Volunteers
- 150 people
- Sponsor
- University Medical Centre Ljubljana
Pulmonary Edema
Screening for Individual Susceptibility Factors to Immersion Pulmonary Edema
Immersion Pulmonary Edema (IPE) is a relatively new form of hemodynamic pulmonary edema. The number of cases has been increasing over the last ten years and it has become the second most common cause of hospitalization for…
- Trial name
- RFSI-OPI (NCT05049889)
- Testing
- Terrestrial exercise, Swimming exercise, Transthoracic cardiac ultrasound
- Where
- 2 sites in France
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Heart Failure, Congestive
Evaluation of MRI Measures of Lung Water With Posture Changes in Healthy Volunteers and in Patients With Cardiac Failure
The aim of this study is to establish a model for the evaluation of drug targets using postural measures to induce changes in lung water concentration as assessed by MRI.
- Trial name
- NCT01277679
- Testing
- MRI
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Edema, Heart Failure
Effect of Normatec Pump for Relief of Leg Edema
The investigators hypothesize that leg edema will decrease rapidly when using the NormaTec pump, patients will lose weight, will feel better, will be less prone to infections in their legs and to congestion of the liver.
- Conditions
- Edema, Heart Failure, Pulmonary Hypertension
- Trial name
- NCT01112150
- Testing
- NormaTec Pump
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Hillel Yaffe Medical Center
Acute Cardiogenic Pulmonary Edema
Non Invasive Mechanical Ventilation in Acute Cardiogenic Pulmonary Edema
Cardiogenic pulmonary edema (CPE) is a common medical emergency and noninvasive ventilation (NIV) in addition to conventional medical treatment might be beneficial for patients with CPE.
- Trial name
- NCT00912158
- Testing
- standard therapy (ST), CPAP, BIPAP
- Where
- Egypt
- Volunteers
- 129 people
- Sponsor
- Assiut University
Lung Cancer (Non-Small Cell), Radiation
Early Prophylactic Versus Late Salvage Recombinant Human Endostatin in Managing Radiosurgery-Induced Brain Injury for NSCLC Brain Metastases
Primary Purpose:To preliminarily evaluate the efficacy and safety of recombinant human endostatin (Endostar) in the early prophylactic cohort (Cohort A) and late salvage cohort (Cohort B) for radiation-induced brain injury after…
- Conditions
- Lung Cancer (Non-Small Cell), Radiation, Brain Injury, Brain Edema
- Trial name
- NCT07841106
- Testing
- Recombinant Human Endostatin (Endostar)
- Volunteers
- 49 people
- Sponsor
- Jiangmen Central Hospital
Congestive Heart Failure, Cardiomyopathy
FAST (Fluid Accumulation Status Trial)
Heart failure is a progressive disease that decreases the pumping action of the heart. This may cause a backup of fluid in the heart and may result in heart beat changes.
- Conditions
- Congestive Heart Failure, Cardiomyopathy, Dyspnea, Pulmonary Edema
- Trial name
- NCT00289276
- Testing
- Fluid Status Monitoring (OptiVol™)
- Where
- 16 sites in United States, Canada and 1 more
- Volunteers
- 156 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
ARDS, Human, Lung, Wet
Treatment of ARDS With Instilled T3
It is hypothesized that instillation of Liothyronine Sodium (T3) into the airspace will be safe, well tolerated, and will increase alveolar fluid clearance and decrease inflammation in patients with ARDS, reflected in improved…
- Conditions
- ARDS, Human, Lung, Wet, Thyroid, Pulmonary Edema
- Trial name
- ARDS+T3 (NCT04115514)
- Testing
- Liothyronine Sodium (T3+0.9% sodium chloride) modified formulation specifically for airway instillation., Non-intervention
- Where
- 2 sites in United States
- Volunteers
- 68 people
- Sponsor
- University of Minnesota
Cardiogenic Pulmonary Edema
Helmet CPAP Versus HFNC in Acute Cardiogenic Pulmonary Edema
This study objectively held to compare the physiological outcomes in the non-invasive (NIV) treatment of Acute Cardiogenic Pulmonary Oedema (ACPE) patients in the Emergency Department (ED) delivered by Helmet CPAP (hCPAP) and…
- Trial name
- HCPAPvsHFNC (NCT04005092)
- Testing
- hCPAP versus HFNC
- Where
- Malaysia
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Hospital Raja Permaisuri Bainun
Dyspnea, Peripheral Edema
NT-proBNP and New Biomarkers in Patients With Dyspnea and/or Peripheral Edema
The objectives of this study are to: Evaluate the sensitivity and specificity of NT-proBNP (N-terminal prohormone brain natriuretic peptide) and new biomarker measurements for the diagnosis of heart failure in patients with acute…
- Trial name
- MANPRO (NCT00143793)
- Where
- Germany
- Volunteers
- 400 people
- Sponsor
- Universitätsmedizin Mannheim
Pregnancy Complications, Ultrasound Therapy; Complications
Lung Ultrasound Patterns Preeclampsia
Evaluation of lung ultrasound as a diagnostic tool in pregnant patients.
- Conditions
- Pregnancy Complications, Ultrasound Therapy; Complications, Pulmonary Disease, Pulmonary Edema
- Trial name
- NCT03576092
- Testing
- Lung Ultrasound
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Cardiogenic Shock, Pulmonary Edema Cardiac Cause
Hemodynamic Evaluation of Left Atrial Pressure in Relationship to Pulmonary Capillary Wedge Pressure in Cardio Thoracic Patients
Accurate hemodynamic monitoring is critical in cardiothoracic surgery, where left atrial pressure (LAP) serves as the gold standard for assessing left-sided cardiac filling pressures.
- Trial name
- HEART (NCT07163052)
- Volunteers
- 136 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
SARS-CoV-2 Infection
Microvascular Injury and Distal Thrombosis in COVID-19
Investigators aimed to better understand the pathophysiology of SARS-CoV-2 pneumonia in non-critically ill hospitalized patients secondarily presenting with clinical deterioration and increase in oxygen requirement
- Trial name
- MIND (NCT04990505)
- Testing
- lung ventilation/perfusion scintigraphy
- Where
- Monaco
- Volunteers
- 25 people
- Sponsor
- Centre Hospitalier Princesse Grace
High Altitude Pulmonary Hypertension
Cerebral Tissue Oxygenation in Highlanders/Lowlanders
The purpose of the current study is to evaluate the cerebral tissue oxygenation of Kyrgyz highlanders with high altitude pulmonary hypertension (HAPH) by performing a longitudinal cohort study.
- Trial name
- NCT03172429
- Where
- Kyrgyzstan
- Volunteers
- 79 people
- Sponsor
- University of Zurich
Pulmonary Edema
Thoracic Fluid Content During Hypervolemic Hemodilution
Thoracic fluid content (TFC) is one of the many variables measured by the ICON electrical cardiometry (EC) device (Osypka Medical).
- Trial name
- NCT04689516
- Testing
- Thoracic fluid content estimation
- Where
- Egypt
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Cairo University
Acute Mountain Sickness, High Altitude Pulmonary Edema
Sleep and Cerebral Responses to High Altitude
Mechanisms underlying high-altitude intolerance as well as exercise performance limitation in hypoxia still remain to be fully understood.
- Conditions
- Acute Mountain Sickness, High Altitude Pulmonary Edema, High Altitude Cerebral Edema
- Trial name
- VALLOT 2011 (NCT01565603)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Acute Coronary Syndrome, Diabetes Mellitus
Acute Coronary Syndrome in Diabetic Patients
This study aims to compare the clinical profile and outcomes of acute coronary syndrome patients with diabetes and without diabetes.
- Conditions
- Acute Coronary Syndrome, Diabetes Mellitus, Heart Failure, Acute Pulmonary Edema
- Trial name
- NCT03607201
- Testing
- No intervention
- Where
- Indonesia
- Volunteers
- 86 people
- Sponsor
- Tarumanagara University
Lung Transplant
Decreasing Edema With a Novel OCS Solution Trial
This is a prospective, multicenter randomized trial of lung transplant recipients transplanted with either a DBD or DCD donor lungs.
- Trial name
- DENOVO (NCT07340710)
- Testing
- OCS Lung System, Static Cold Storage
- Volunteers
- 450 people
- Sponsor
- TransMedics