Clinical trials: Edema Leg
Lymphedema of Leg
Hydrophobic Tubes for the Treament of Lower and Upper Limb Lymphedema
Lymphedema is a chronic condition causing fluid buildup in affected limbs. Traditional treatments often fall short, but subcutaneous implantation of hydrophobic silicone tubes shows promise, creating artificial drainage pathways.
- Trial name
- NCT05970068
- Testing
- implantation of hydrophobic tubes for edema fluid drainage, Best Medical Treatment
- Where
- Portugal
- Volunteers
- 20 people
- Sponsor
- Universidade do Porto
Heart Failure
Lancashire Objective Volume Evaluation of Leg Oedema in Heart Failure Second Pilot
Patients with heart failure (HF) who recently received treatment with IV diuretics for worsening congestion or outpatients with HF and peripheral oedema treated with at least 80 mg furosemide (or equivalent)/day will be recruited…
- Trial name
- LOVE-HF-2 (NCT04787393)
- Testing
- Heartfelt device, Connected weighing scales
- Where
- United Kingdom
- Volunteers
- 23 people
- Sponsor
- Heartfelt Technologies
Edema Leg, Pain
Does Edema Affect the Adjustment of TENS Amplitude
The goal of this pre-post clinical trial is to compare the amplitude settings of three different frequency TENS modes (Conventional TENS, LF TENS, HF TENS) in patients who had undergone total knee arthroplasty, both with the…
- Trial name
- NCT06153277
- Where
- Turkey (Türkiye)
- Volunteers
- 125 people
- Sponsor
- Karamanoğlu Mehmetbey University
Lower-Limb Lipedema, Lipedema
"Effect of Endermologie-Assisted Physiotherapy on Edema, Pain, and Functional Recovery After Liposuction for Lower-Limb Lipedema"
Lipedema is a chronic condition that mainly affects women and causes abnormal fat accumulation, pain, heaviness, tenderness, swelling, and difficulty with movement, especially in the lower limbs.
- Trial name
- NCT07618065
- Testing
- Endermologie-Assisted Physiotherapy, Standard Postoperative Physiotherapy
- Where
- 2 sites in Egypt
- Volunteers
- 88 people
- Sponsor
- Cairo University
Anterior Cruciate Ligament Injuries
TCM for Post-operative Edema
There are loads of research on knee surgery, including surgical methods, rehabilitation strategies, and complication prevention.
- Trial name
- NCT06335602
- Testing
- LASER acupuncture
- Volunteers
- 120 people
- Sponsor
- Chang Gung Memorial Hospital
Edema Leg
A New Intelligent Stocking for Quantification of Edema in the Lower Limbs
The purpose of the study is to evaluate a prototype of an intelligent stocking (Edema Stocking Device [ESD]), consisting of two stretch sensitive sensors, as a new method for continuously lower leg volume monitoring.
- Trial name
- NCT05310435
- Testing
- Single volume measurement with ESD, Single volume measurement with WDV, Single circumference measurement with tape measure
- Where
- Denmark
- Volunteers
- 6 people
- Sponsor
- University of Aarhus
Lymphatic Edema, Cellulitis of Leg
Efficacy of Complex Decongestive Therapy (CDT) in Patients With Venous Insufficiency: a Experimental Study
The study investigates the effectiveness of Complex Decongestive Therapy (CDT) in improving venous flow and reducing symptoms in venous insufficiency patients.
- Conditions
- Lymphatic Edema, Cellulitis of Leg, Vein Disease
- Trial name
- CDT (NCT06231940)
- Testing
- Complex Decongestive Therapy (CDT) in venous insufficiency,
- Where
- Spain
- Volunteers
- 21 people
- Sponsor
- University of Salamanca
Lymphedema, Gait Dysfunction
Impact of Virtual Reality (VR) Based Exercises on Lower Limb Lymphedema Outcomes (LELO)
This randomized controlled study aims to investigate the effects of virtual reality (VR)-assisted gait training, in addition to Complex Decongestive Therapy (CDT), on gait parameters, physical function, quality of life, and edema…
- Conditions
- Lymphedema, Gait Dysfunction, Physical Rehabilitation, Chronic Edema
- Trial name
- VR-LELO (NCT07472543)
- Testing
- Complex Decongestive Therapy (CDT) plus virtual reality (VR)-assisted gait training group, Complex Decongestive Therapy alone group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Venous Insufficiency of Leg
SOCKNLEG Compression Stocking Kit : User Friendliness
The investigators aim to evaluate the user friendliness of a newly designed leg compression stocking kit, the SOCKNLEG, compared to a standard leg compression stocking of the same compression strength, the SIGVARIS Cotton.
- Trial name
- SOCKNLEGZH (NCT03429959)
- Testing
- SOCKNLEG, SIGVARIS Cotton
- Where
- Switzerland
- Volunteers
- 47 people
- Sponsor
- University of Zurich
Weaning, Spontaneous Breathing Trial
Prediction Of Pulmonary Edema With Müller Maneuver
The mechanical ventilation weaning must begin as early as possible to limit its complications and requires a spontaneous breathing trial (SBT) before the separation from the ventilator to the patient.
- Trial name
- PoEM (NCT05358405)
- Testing
- Müller maneuver
- Where
- France
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Idiopathic Edema
Efficacy and Safety Evaluation of Changes in Lower Extremity Edema of Radiofrequency
The purpose of this study is to verify the efficacy and safety of the radiofrequency stimulation compared to the sham stimulation in reducing lower extremity edema in adult women with idiopathic edema.
- Trial name
- NCT05185193
- Testing
- radiofrequency
- Where
- South Korea
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Pusan National University Yangsan Hospital
Lower Limb Chronic Oedema
Oedema Study : Chroedem
The chroedem study is aiming to assess tissue and biomolecular components of chronic lower limb oedema (CO). The investigators working hypothesis is that according to the aetiology of CO, the proportion of oedema \& composition…
- Trial name
- CHROEDEM (NCT02914808)
- Testing
- Patients will undergo a lower limb MRI and blood tests
- Where
- 3 sites in France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Montpellier
Varicose Veins, Pregnancy Related
Graduated Elastic compRession for vAricose Veins in PrEgnancy
This study will be evaluate the clinical efficacy of using graduated compression hosiery for venospecific symptoms, leg edema, and quality of life (QoL) in pregnant women with varicose veins (VV's).
- Conditions
- Varicose Veins, Pregnancy Related, Quality of Life
- Trial name
- GRAPE (NCT05122195)
- Testing
- Compression therapy
- Where
- 2 sites in Belarus
- Volunteers
- 80 people
- Sponsor
- Belarusian State Medical University
Venous Insufficiency of Leg, Venous Reflux
Efficacy of Vasculera in Prevention on Post-op Pain and Edema Following Lower Extremity Venous Treatment in the Outpatient Setting
The purpose of this study is to evaluate the effectiveness of Vasculera in reducing post procedural pain, bruising and edema in the post procedure period for patients diagnosed with C2-C5 disease requiring an intervention(s).
- Conditions
- Venous Insufficiency of Leg, Venous Reflux, Varicose Veins, Lower Extremity Edema Chronic
- Trial name
- NCT02936271
- Testing
- Vasculera
- Where
- United States
- Sponsor
- Corewell Health West
Edema Leg, Venous Insufficiency of Leg
Discovering the Effect of Venous Insufficiency on Nocturia (DEVINe)
Nocturia, or waking during the night to pass urine, is a multifactorial disease. An important cause of nocturia are peripheral edema due to accumulation of fluid in the lower limbs.
- Conditions
- Edema Leg, Venous Insufficiency of Leg, Nocturia, Bio-Impedance Measurements
- Trial name
- DEVINe Pilot (NCT03928197)
- Testing
- Tilt Test, Inbody S10, Tape measurements
- Where
- Belgium
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Venous Leg Ulcer, Lymphovenous Edema
Lymphovenous Bypass Manage Venous Leg Ulcers
Leg ulcers are areas of epidermal discontinuity in lower limbs with causes of venous, arterial, diabetic, pressure, traumatic, allergic, or inflammation.
- Trial name
- NCT05068258
- Testing
- Lymphovenous bypass, including lymphaticovenular anastomosis/implantation
- Where
- Taiwan
- Volunteers
- 31 people
- Sponsor
- National Taiwan University Hospital
Gynecologic Cancer
Randomized Trial of Exercise on Lower Extremity Edema After Lymphadenectomy in Gynecologic Cancer
The primary outcome is the change in lower extremity edema-related symptoms. Secondary outcomes include the compliance rate of management guidelines for lower extremity edema, the performance rate for pelvic and lower extremity…
- Trial name
- NCT01849224
- Testing
- Pelvic and lower extremity exercise
- Where
- South Korea
- Volunteers
- 148 people
- Sponsor
- National Cancer Center, Korea
Heart Failure，Congestive, Leg Edema
The ROle of Compression StocKings in Heart Failure Patients
Congestive heart failure (CHF) occurs when the heart is weak and not able to effectively pump blood to the body. One of the common manifestations of CHF is fluid overload and swelling of the legs.
- Conditions
- Heart Failure，Congestive, Leg Edema, Venous Insufficiency, Venous Ulcers
- Trial name
- ROCK-HF (NCT06350695)
- Testing
- low grade compression stockings (10-15 mmHg), high grade compression stockings (20-30 mmHg)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Maryland, Baltimore
Diabetes, Diabetic Foot Ulcer
The Mount Sinai Diabetic Foot Ulcer Prospective Trial
The purpose of this study is to evaluate whether placing stent(s) for a blockage in a leg vein will help improve the healing of diabetic foot ulcers (DFU).
- Conditions
- Diabetes, Diabetic Foot Ulcer, Edema
- Trial name
- NCT03404895
- Testing
- Conventional Therapy, Venous Stent(s)
- Where
- United States
- Sponsor
- Windsor Ting
Diabetic Foot Ulcer, Pressure Injury
A Dual-center Study Evaluating Clinical Acceptance of a NPWT Wound Care System
The purpose of this study is to determine if use of the Medela Invia Motion NPWT system supports acceptable progress towards the goal of therapy when treating patients with a variety of wound types during the evaluation period.
- Conditions
- Diabetic Foot Ulcer, Pressure Injury, Pressure Ulcer, Surgical Wound
- Trial name
- NCT04593693
- Testing
- Invia Motion Endure NPWT system
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- Medela AG