Clinical trials: Effect Neonatal
Respiratory Distress Syndrome in Premature Infant, Bronchopulmonary Dysplasia
Safety, Pk and Anti-inflammatory Effects of CC10 Protein in Premature Infants With Respiratory Distress Syndrome (RDS)
Bronchopulmonary Dysplasia (BPD) is a multi-factorial disease process that is the end result of an immature, surfactant deficient lung that has been exposed to hyperoxia, mechanical ventilation and infection.
- Trial name
- NCT01473264
- Testing
- recombinant human CC10 (rhCC10)
- Where
- 4 sites in United States
- Volunteers
- 22 people
- Sponsor
- Clarassance, Inc.
Prematurity of Fetus
Effect of Prematurity on Renal Function in 5 Years Old Children
Purpose of the study: 1. To evaluate the effect of prematurity on renal function in 5 years old children 2. To compare former premature children treated by ibuprofen in the neonatal period to controls
- Trial name
- SUIVIREIN (NCT00817921)
- Where
- 3 sites in France
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Jean Michel Hascoet
Syndrome, Down
Effects of Kendall Exercise VS Gong's Mobilization on Pain, Range of Motion, Function, and Strength in Cases With UCS
The effectiveness of kendall exercise vs. gong's mobilization for alleviating pain with improvment in range of motion, function and strength in cases with upper cross syndrome, assessed by dividing 44 patinets in two groups as…
- Trial name
- NCT06486207
- Testing
- Gong's mobilization, Kendall Exercise
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Superior University
Pregnancy
Effect During Pregnancy and Intrapartum Health
Assessing the role of moderate exercise in newborn intrapartum variables have showed to be crucial not only on prescribing exercise safely, but also on understanding its impact on the prevention of some cardio-metabolic diseases…
- Trial name
- NCT03348332
- Testing
- Exercise pregnant women
- Where
- Spain
- Volunteers
- 530 people, healthy volunteers welcome
- Sponsor
- Technical University of Madrid
Cystic Fibrosis
Effect of Azithromycin on Fatty Acids in CF
In collaboration with Dr.Birgit Alteheld, Institute of Nutrional Sciences of the university of Bonn, Germany the following effect is explored: Effect of a 4 week therapy with AZT on synthesis of lipoproteins as well as…
- Trial name
- NCT03045198
- Testing
- Azithromycin
- Volunteers
- 20 people
- Sponsor
- University Childrens' Hospital (Zentrum für Kinderheilkunde des Universitätsklinikum Bonn)
Cystic Fibrosis
Effects of Inhaled Bicarbonate on Airway pH in Cystic Fibrosis
This study will compare the use of inhaled concentrated sodium chloride solution to an inhaled solution of sodium bicarbonate in an attempt to decrease the thickness and stickiness of the mucus in the lungs of a person with…
- Trial name
- NCT03391414
- Testing
- hypertonic bicarbonate, sodium chloride
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Joseph Pilewski
Thalassemia Major
The Effect of N-acetylcysteine on Oxidative Stress Status and Iron Overload in Thalassemia Major
The effect of N-acetylcysteine as antioxidant and its effect on pretransfusion hemoglobin and iron overload in patients with thalassemia were compared to patients who didn't receive n-acetylcysteine after 3 months of study…
- Trial name
- NCT04260516
- Testing
- N-acetyl cysteine
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Beni-Suef University
Neonatal Abstinence Syndrome, Aromatherapy
The Effect of Aromatherapy on Neonatal Abstinence Syndrome and Salivary Cortisol Levels
Determine the effectiveness of lavender and chamomile aromatherapy of mitigation of symptoms of Neonatal Abstinence Syndrome
- Trial name
- NCT03097484
- Testing
- lavender and chamomile essential oils
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- John M. Daniel
Pain, Infant ALL
Effect of Leg and Heel Massage on Pain During Heel Blood Collection Newborns
This study was planned to evaluate the effect of leg and heel massage on newborns, the pain experienced during heel blood collection, and the effects on physiological parameters.
- Trial name
- NCT06567093
- Testing
- Baby Foot and Leg Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bartın Unıversity
Hematologic Disease, Hemophilia A
BAY14-2222 Prophylaxis and Joint Function Improvement (Adults)
The purpose of the study is to evaluate the effect of prophylactic treatment on the number of joint bleeds and quality of life in severe hemophilia A subjects compared to on-demand treatment in a one-group two-treatment schedule…
- Trial name
- NCT00586521
- Testing
- Kogenate (BAY14-2222)
- Where
- 11 sites in United States, France and 3 more
- Volunteers
- 20 people
- Sponsor
- Bayer
Congenital Heart Disease (CHD), Postoperative Respiratory Dysfunction
Effect of Coughing Exercises Versus Incentive Spirometry on Respiratory Function and Recovery in Children After Cardiac Surgery.
This study examines the effects of coughing exercises and incentive spirometry (IS) on lung function and recovery in children who undergo heart surgery.
- Conditions
- Congenital Heart Disease (CHD), Postoperative Respiratory Dysfunction, Postoperative Recovery After Cardiac Surgery
- Trial name
- CEXIS (NCT07405333)
- Testing
- Coughing Exercises, Incentive Spirometry, Standard Postoperative Care
- Where
- 4 sites in Iraq
- Volunteers
- 99 people
- Sponsor
- University of Baghdad
Irritable Bowel Syndrome Constipation Predominant
Effects of ROSE-010 on GI Transit in Constipation Predominant Irritable Bowel Syndrome (C-IBS) Patients
This trial will study the effects of an investigational (not FDA approved) medication, ROSE-010, on the movement of food through the stomach, small intestine and colon in females with constipation predominant irritable bowel…
- Trial name
- NCT01056107
- Testing
- ROSE-010
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Mayo Clinic
Down Syndrome
Effect of Sensory Integration on Gross and Balance on Children With Down Syndrome
To investigate the effect of sensory integration on gross motor function in children with Down syndrome. To investigate the effect of sensory integration on balance in children with Down syndrome.
- Trial name
- NCT07785011
- Testing
- BALANCE AND SENSORY INTEGRATION
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Raheel Sanad
Sleep Apnea Syndromes in Children, Functional Orthodontic Treatment
Evaluation of Functional Orthodontic Treatment on Sleep Quality
Functional appliances are used in the treatment of Class II anomalies caused by mandibular rethrognathia. Herbst which is a fixed and rigid functional appliance and TWB which is removable appliance can be successful in the…
- Conditions
- Sleep Apnea Syndromes in Children, Functional Orthodontic Treatment, Mandibular Retrognathia, Upper Airway
- Trial name
- NCT06660771
- Testing
- Functional orthodontic treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Gökçenur Gökçe Kara
Melanoma
The Effects of Treatment With Vemurafenib on the Immune System in Advanced Melanoma
Approximately 40-60 % of cutaneous melanomas select for a mutation in a protein called BRAF which is part of a signaling pathway called the Mitogen Activated Protein Kinase (MAPK) pathway.
- Trial name
- NCT01942993
- Testing
- Vemurafenib
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Philip Friedlander
Hearing Loss, Neonatal
Mode of Delivery on Newborn Hearing Test
Neonatal hearing screening may fail due to some perinatal and neonatal factors. It is well known that false positivity increases cost and maternal anxiety and anxiety in the neonatal hearing screening.
- Trial name
- NCT03881514
- Where
- Turkey (Türkiye)
- Volunteers
- 1,000 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Pregnancy Related, Anxiety in Pregnancy
The Effect of Exposure to an Informative Video About Amniocentesis Before the Procedure on Maternal Anxiety
The effect of exposure to an informative video about amniocentesis before the procedure on maternal anxiety
- Conditions
- Pregnancy Related, Anxiety in Pregnancy, Amniocentesis Affecting Fetus or Newborn
- Trial name
- NCT05463549
- Testing
- Informative video
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Cleft Palate
Optic Nerve Sheath Diameter Measurement in Cleft Palate Repair
The aim of this study is to evaluate the effect of the Boyle-Davis mouth opener, which is routinely used in cleft palate surgery, on intracranial pressure by USG-guided optic nerve sheath diameter measurement, which is a…
- Trial name
- NCT04718558
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Karadeniz Technical University
Cleft Palate Children, Speech Therapy
Effect and Cost-utility of of High Intensity vs. Low Intensity Speech Intervention in Children With Cleft Palate
Achieving speech that is understandable and acceptable to others is the key outcome in cleft treatment. Therefore, speech therapy provided by a speech-language pathologist is necessary.
- Conditions
- Cleft Palate Children, Speech Therapy, Speech Disorders in Children, Cleft Lip and Palate
- Trial name
- NCT06381713
- Testing
- High intensive combined phonetic-phonological intervention, Low intensive combined phonetic-phonological intervention
- Where
- Belgium
- Volunteers
- 70 people
- Sponsor
- University Ghent
Obstetrical Complication of Anesthesia
Effects of Intraoperative Oxygen Therapy on Oxygenation of Newborns Born Via Elective Cesarian Section
In this study the investigators examine the effects of intraoperative oxygen administration to the mother on certain enzyme functions of the newborn.
- Trial name
- NCT02804555
- Testing
- Oxygen
- Where
- Hungary
- Volunteers
- 107 people
- Sponsor
- Szeged University
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