Clinical trials: Effect Neonatal
Irritable Bowel Disease
(FODMAP) Diet on Improving Symptoms of Patients With Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) is a common disorder of gut-brain interaction, characterized by chronic abdominal pain and altered bowel habits.
- Trial name
- NCT07299305
- Testing
- Low Fermentable, Oligo-, Di-, Monosaccharides and Polyols (FODMAP) Diet
- Where
- Egypt
- Volunteers
- 183 people
- Sponsor
- Zagazig University
Bone Diseases, Metabolic, Acid-Base Imbalance
The Effect of Potassium Bicarbonate on Bone and Several Physiological Systems During Immobilisation
Mainly due to the absence of gravitational forces in weightlessness, astronauts suffer from an increased bone loss- negatively affecting health and vitality during a mission.
- Conditions
- Bone Diseases, Metabolic, Acid-Base Imbalance, Muscular Atrophy, Sprains and Strains
- Trial name
- NUC (NCT01509456)
- Testing
- Potassium Bicarbonate
- Where
- Germany
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- DLR German Aerospace Center
Neonatal Diabetes
Effect of Food Composition on Postprandial Insulin Secretion in Neonatal Diabetes
Neonatal diabetes is diagnosed before 6 months of age and causes high blood glucose levels due to the pancreas not secreting insulin. Neonatal diabetes can be caused by a change in a DNA region called the KCNJ11 gene.
- Trial name
- FoND (NCT02921906)
- Testing
- High protein meal, High carbohydrate meal, Paracetamol
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Royal Devon and Exeter NHS Foundation Trust
Pes Planus
Investigation of the Effects of Short Foot Exercise and Mobilization in Young Adults With Pes Planus
Pes Planus (PP) is a foot deformity characterized by a lower-than-normal medial longitudinal arch. Individuals diagnosed with PP experience various challenges in daily life.
- Trial name
- NCT07107763
- Testing
- short foot exercise, Mobilization, Short foot exercise and mobilization
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Kirsehir Ahi Evran Universitesi
Flexible Flatfoot
The Effect of Sensorimotor Insoles on Gait Parameters in Adults With Flexible Flatfoot
The flatfoot is one of the most common diagnosis in foot. The main goals of its orthotic intervention in adult population are the control of the rearfoot and midfoot movement, the affection of the forefoot position and the…
- Trial name
- NCT04125407
- Testing
- Sensorimotor foot orthoses
- Where
- Czechia
- Volunteers
- 32 people
- Sponsor
- Palacky University
Apnea of Newborn, Preterm Labor
Analyze Changes in Respiratory Rate When Using the Scare Respirator
Pilot study of 10 preterm, who are going to be randomly placed to 3 phases : 2 hour of basal observation of respiratory rate, heart rate, saturation, NIPS and aEEG recording, 2 hours with a 20cycles/minute with "scare…
- Trial name
- RESPSUS (NCT04584814)
- Testing
- without any device, scare ventilator at 20, scare ventilator at 40
- Where
- Chile
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Muscular Dystrophy, Duchenne, Upper Extremity
The Effects of Trunk Exercises on Upper Extremity and Respiratory Functions in DMD
The aim of this study was to investigate the effects of trunk training on trunk control, upper extremity, and pulmonary function in children with Duchenne muscular dystrophy (DMD).
- Conditions
- Muscular Dystrophy, Duchenne, Upper Extremity, Respiratory Functions
- Trial name
- NCT04669847
- Testing
- Trunk-oriented exercise program, Conventional exercise program
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Gokce Yagmur Gunes Gencer
Anterior Crossbite, Class III Malocclusion
Evaluation of the Treatment Effects of Tooth Borne Versus Bone-anchored Protraction Procedures in Class III Patients With Maxillary Deficiency
The aim of this prospective randomized controlled clinical study is to compare the effects of bone-anchored and tooth borne maxillary protraction on dentofacial structures in skeletal Class III patients.
- Conditions
- Anterior Crossbite, Class III Malocclusion, Maxillary Deficiency
- Trial name
- NCT04863404
- Testing
- Face mask with hybrid-hyrax, Face mask with conventional bonded RME
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Quality of Life, Congenital Heart Disease
Exercise Training in Children With Corrective Cardiac Surgeries
To determine the effects of preoperative exercise therapy on postoperative cardiopulmonary outcomes and quality of life in children with corrective cardiac surgeries.Within literature there is limited evidence on preoperative…
- Conditions
- Quality of Life, Congenital Heart Disease, Heart; Surgery, Heart, Functional Disturbance as Result
- Trial name
- NCT05763238
- Testing
- INTERVENTION GROUP, CONTROL GROUP
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Riphah International University
Pneumonia
Effect of Prolonged Slow Expiration Technique on Blood Gases Among Pneumatic Neonates
Pneumonia is a medical condition that, if not treated promptly, can lead to life- threatening complications. The prolonged slow expiration technique is a new type of chest physiotherapy that helps infants discharge bronchial…
- Trial name
- NCT05781464
- Testing
- Traditional chest physiotherapy, Prolonged slow expiration technique
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Cairo University
Chronic Respiratory Disease, Cystic Fibrosis
The Effect of Proprioceptive Neuromuscular Facilitation (PNF) Technique for Children With Chronic Pulmonary Diseases.
Cystic fibrosis and bronchiectasis are the most seen problems in children with chronic pulmonary diseases. İt is a genetic, chronic system disease that reduces life expectancy, and life quality as well.
- Conditions
- Chronic Respiratory Disease, Cystic Fibrosis, Bronchiectasis
- Trial name
- NCT03420209
- Testing
- Group applying PNF technique
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul University
Neonatal Hyperbilirubinemia, Newborn Care Phototherapy
Massage, Tub Bathing, and Sponge Bathing Effects on Neonatal Bilirubin and Comfort
This randomized controlled trial evaluates the effects of massage, tub bathing, and sponge bathing on bilirubin levels, skin integrity, neonatal comfort, and physiological parameters in term newborns undergoing phototherapy
- Trial name
- NEO-BATH (NCT07084987)
- Testing
- neonatal massage, Tub Bathing, sponge bath
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Uludag University
Sickle Cell Disease, Hemolytic Anemia
Long Term Effects of Erythrocyte Lysis
In this prospective observational trial, participants with chronic hemolysis will be assessed with echocardiogram for elevated tricuspid jet velocity and other evidence of pulmonary hypertension.
- Trial name
- NCT00842621
- Testing
- Clinical Evaluations, Laboratory Studies
- Where
- United States
- Volunteers
- 390 people
- Sponsor
- St. Jude Children's Research Hospital
Neonatal Sepsis
Effect of N-acetylcysteine as Adjunct Therapy on the Clinical Outcome of Neonatal Sepsis
Neonatal sepsis (NS) is a life-threatening condition characterized by systemic inflammation in response to infection during the first 28 days of life.
- Trial name
- NCT07380347
- Testing
- N-Acetyl Cysteine (NAC), Normal Saline
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Exercise Addiction, Cardiovascular Abnormalities
Exercise Addiction and Health Risks in Gym Users
This observational study aims to investigate the prevalence of musculoskeletal injuries and cardiovascular risk factors among individuals with and without exercise addiction.
- Trial name
- NCT07061509
- Testing
- Battery of Physical and Psychological Assessments
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Saglik Bilimleri Universitesi
Complication of Anesthesia, Ischaemia-reperfusion Injury
Dexmedetomidine Effect on Mitochondrial Function
The investigators hypothesize that in addition to a known sympatholytic effect, intraoperative dexmedetomidine reduces adverse changes in mitochondrial function and structure attenuating ischaemia-reperfusion and end-organ injury…
- Trial name
- NCT02299063
- Testing
- Dexmedetomidine, 0.9% NaCl
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- The Hospital for Sick Children
Dermatitis, Atopic
A Study to Evaluate the Safety, Tolerability, Drug Levels, and Drug Effects of BMS-986326 in Participants With Atopic Dermatitis
The purpose of this study is to assess the safety, tolerability, drug levels, drug effects, and impact on disease severity of BMS-986326 in participants with moderate-to-severe atopic dermatitis (AD).
- Trial name
- NCT06248814
- Testing
- BMS-986326
- Where
- 13 sites in Czechia, France and 3 more
- Volunteers
- 64 people
- Sponsor
- Bristol-Myers Squibb
Preterm Birth
The Effects of Lactobacillus Reuteri DSM 17938 on Immunomodulation and Gastric Motility in Preterm Newborns
The investigators propose a Phase II interventional trial to investigate the role of Lactobacillus reuteri DSM 17938 on the intestinal motility and immune response of premature infants and further evaluate safety of the use of…
- Trial name
- NCT00985816
- Testing
- Lactobacillus Reuteri
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- University of Bari
Huntington's Disease
A Study to Evaluate the Effect of SAGE-718 on Cognitive Function in Participants With Huntington's Disease (HD)
The primary purpose of this study is to evaluate the effect of SAGE-718 on cognitive performance and functioning in participants with HD.
- Trial name
- NCT05107128
- Testing
- SAGE-718
- Where
- 49 sites in United States, Australia and 2 more
- Volunteers
- 189 people
- Sponsor
- Supernus Pharmaceuticals, Inc.
Dermatitis Atopic
An Open-label, DDI Study to Investigate the Effects of Amlitelimab on the PK of Selected Cytochrome P450 Substrates
This is an open-label, single group, 2-period, Phase 1, single-sequence study. The study duration will be up to 342 days. The treatment period will be up to Week 29, where Week 29 is defined as End of Treatment (last amlitelimab…
- Trial name
- NCT06686628
- Testing
- Amlitelimab, Midazolam, Caffeine
- Where
- Germany
- Volunteers
- 23 people
- Sponsor
- Sanofi
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