Clinical trials: Effect Neonatal
Quality of Life, Muscle Weakness
Effects of Progressive Resistance Training Compared With Aerobic Training in Patients With Hemophilia
This study aims to assess the effects of progressive resistance training compared with aerobic training, among those with hemophilia. Participants will be divided into two groups.
- Trial name
- NCT04892628
- Testing
- Progressive resistance training, Aerobic training
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Dow University of Health Sciences
Healthy
Effect of Multisensory (Snoezelen) Environment on Birth Outcomes
Giving birth is a fundamental life event that women will remember throughout their lives. While seeking perfection for the birth environment, much can be learned from other areas of expertise and different pursuits can be…
- Trial name
- NCT06732544
- Testing
- snoezelen room, routine delivery room
- Where
- Turkey (Türkiye)
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Amasya University
Irritable Bowel Syndrome, Digestive System Diseases
Efficacy of a Multi-strain Probiotic in the Treatment of Irritable Bowel Syndrome
The Canadian College of Naturopathic Medicine is conducting a research study on Irritable Bowel Syndrome (IBS), a common condition in North America.
- Conditions
- Irritable Bowel Syndrome, Digestive System Diseases, Colonic Diseases, Functional, Colitis, Mucous
- Trial name
- IBS (NCT01887834)
- Testing
- Kyodophilus multi-strain probiotic capsules
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- The Canadian College of Naturopathic Medicine
Wrinkle, Scar
Pre-marketing Trial to Assess Safety and Efficacy of 'Volumizing Filler Based on Hyaluronic Acid and Recombinant Collagen'
Study to validate the safety and efficacy of the Hyaluronic Acid +Collagen filler 40 patients will undergo through 3 visits one to asses the health and apply the filler one after 4 weeks to check the results one after 16 weeks…
- Conditions
- Wrinkle, Scar, Laxity; Skin
- Trial name
- NCT06336044
- Testing
- Karisma
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Taumedika s.r.l.
Breast Feeding, Exclusive, Hospitalization
The Effect of Chronobiologic Feeding Model on Circadian Rhythm in Newborns
This study was planned to evaluate the effect of "feeding model with chronobiologic approach" on circadian rhythm, growth and physiologic parameters of newborns.
- Conditions
- Breast Feeding, Exclusive, Hospitalization, Feeding Patterns
- Trial name
- NCT05923437
- Testing
- Feeding model group with a chronobiological approach
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Selcuk University
Hemophilia A
Effects of Emicizumab vs. Factor VIII Prophylaxis on Joint and Bone Health in Severe Hemophilia A
The investigators propose to study longitudinal joint and bone density changes in patients with severe Hemophilia A. Per current standard of care, most patients are on prophylactic FVIII replacement therapy intravenously several…
- Trial name
- EmiMSK (NCT04131036)
- Testing
- assessment of joint health and bone density
- Where
- 4 sites in United States
- Volunteers
- 40 people
- Sponsor
- Washington Institute for Coagulation
Pes Planus
Effects of Pes Planus on Quality of Life
This study will be conducted to investigate the effect of pes planus on physical activity level, exercise capacity and quality of life in young adults.
- Trial name
- NCT05836519
- Testing
- Survey Navicular Drop test, International Physical Activity Questionnaire (IPAQ) Short Form, 6-minute walk test, Foot Function Index (AFI), SF-36 quality of life questionnaire, Modified borg scale
- Volunteers
- 32 people
- Sponsor
- Saglik Bilimleri Universitesi
Tibial Muscular Dystrophy
Comparative Effects of Clamshell Technique With EMS vs CTin Iliotibial Band Tightness for Pain and Function
Iliotibial band syndrome (ITBS) is a common knee injury that usually presents with pain and/or tenderness on palpation of the lateral aspect of the knee, superior to the joint line and inferior to the lateral femoral epicondyle.
- Trial name
- NCT06428136
- Testing
- Clamshell exercises with Electrical Muscle Stimulation (CT + EMS), Conservative Treatment (CT)
- Where
- Pakistan
- Volunteers
- 62 people
- Sponsor
- Superior University
Severe Hemophilia
Individualized Exercise Combined With Manual Therapy in Severe Hemophilia Patients With Polyarthropathy
The aim of this study is to investigate the effect of individualized physical therapy, combined manual therapy and exercise intervention, for pain perception, range of motion (ROM), muscle strength, joint health, cardiopulmonary…
- Trial name
- NCT06535971
- Testing
- Manual therapy combined exercise
- Where
- Taiwan
- Volunteers
- 10 people
- Sponsor
- Far Eastern Memorial Hospital
Alpha1-antitrypsin Deficiency
Study of the Effect of Aerosolized, Recombinant Alpha 1-Antitrypsin on Epithelial Lining Fluid Analytes in Subjects With Alpha 1-Antitrypsin Deficiency
The study was a Phase 1B/2A, uncontrolled, open-label, single-center study in individuals with congenital AAT (alpha 1-antitrypsin) deficiency.
- Trial name
- NCT00157092
- Testing
- Aerosolized, Recombinant Alpha 1-Antitrypsin
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Baxalta now part of Shire
Infantile Colic, Infantile Spasm
The Effect of Spa and Massage on Babies on Colic Symptoms
Although various complementary health approaches have been examined to alleviate colic symptoms, there seems to be a limited number of studies on SPA and massage applications.
- Trial name
- NCT05538936
- Testing
- Baby SPA, Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Polycystic Kidney, Autosomal Dominant
Effect of Statin Therapy on Disease Progression in Autosomal Dominant Polycystic Kidney Disease (ADPKD)
The purpose of this study is to determine whether the medication pravastatin will ameliorate renal and cardiovascular disease over a 3-year period in children and young adults with autosomal dominant polycystic kidney disease…
- Trial name
- NCT00456365
- Testing
- pravastatin
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- University of Colorado, Denver
Sickle Cell Disease
Sickle Cell Pro-Inflammatory Response to Interval Training Study
Recommendations for exercise prescription currently do not exist for individuals with sickle cell anemia (SCA) despite the known impact that SCA-related complications has on physical functioning and fitness.
- Trial name
- SPRINTS (NCT03653676)
- Testing
- Exercise Test (CIIT)
- Where
- 3 sites in United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Flat Feet, Lower-Limb Muscle Activation
Plantar Stimulation, Whole-Body Vibration, and Baduanjin for Muscle Activation
This study will examine how different short-term exercise and vibration conditions affect lower-limb muscle activity in young adults with flat feet and young adults with normal feet.
- Conditions
- Flat Feet, Lower-Limb Muscle Activation, Neuromuscular Response
- Trial name
- NCT07811674
- Testing
- Whole-body Vibration Training,Whole-Body Vibration With Regional Plantar Stimulation,Baduanjin
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Vital Signs
The Effect of Postnatal Lying Position on Cerebral Oxygenation in Newborns
In the international delivery room guidelines, it is not specified which position is optimal for the baby stabilization. Here, the investigators want to evaluate the effects of the positions on postnatal adaptation and cerebral…
- Trial name
- NCT05868980
- Testing
- vital signs by postpartum position
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dr. Behcet Uz Children's Hospital
Premature Infant, Bronchopulmonary Dysplasia
The Effects of Position on the Oxygenation Instability of Premature Infants as Documented by SpO2 Histograms
SpO2 instability is in the nature of premature infants. Hypoxic episodes occur spontaneously in many of these infants, especially after the first week of life.
- Trial name
- NCT03546543
- Testing
- Position change
- Where
- Israel
- Volunteers
- 23 people
- Sponsor
- Rambam Health Care Campus
Congenital Heart Disease
The Effect of Fluids Flushed in Pediatric Cardiac Catheterization Procedures on Lung Ultrasound Score
Therapeutic catheterizations substituted many traditional surgical procedures with the advance of transcatheter techniques. Pediatric patients are more liable to fluid overload due to their smaller weights compared to adults and…
- Trial name
- NCT04311918
- Where
- Egypt
- Volunteers
- 43 people
- Sponsor
- Cairo University
Healthy Volunteers Sickle Cell Disease, Thalassemia
A Research Study of the Effect of Etavopivat on Other Drugs in Healthy Participants
The study aims to test if a new medicine called etavopivat potentially affects other medicines in healthy participants. The purpose of the study is to investigate whether the use of etavopivat affects the breakdown and metabolism…
- Trial name
- NCT06813924
- Testing
- Etavopivat, Digoxin, Pitavastatin
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Neonatal, Pain Management
The Effect of Scents Applied During Heel Blood Collection on Newborn Crying Duration, Pain, and Physiological Parameters
One of the most common and painful procedures in newborns is taking a capillary blood sample from the heel. This basic procedure, widely used in early health assessments, particularly in newborn screening tests, can cause mild to…
- Trial name
- Randomized (NCT07350980)
- Testing
- oil
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Infant, Premature, Diseases, Premature Birth of Newborn
Elevated Midline Positioning During Diaper Change in Preterm Infants
Diaper changing is one of the most frequent routine care procedures in the neonatal intensive care unit (NICU) and is known to cause physiological instability and behavioral stress responses in preterm infants.
- Conditions
- Infant, Premature, Diseases, Premature Birth of Newborn, Pain
- Trial name
- NCT07865897
- Testing
- 30-Degree Elevated Midline Positioning, Standard Lateral Position Diaper Change
- Volunteers
- 80 people
- Sponsor
- Akdeniz University
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