Clinical trials: Effect of Drugs
Asthma
A Study of MRx-4DP0004 in Asthma
This is a multicentre, phase I/II, double-blind, placebo-controlled study of MRx-4DP0004 in participants taking long-term medication for asthma.
- Trial name
- NCT03851250
- Testing
- MRx-4DP0004
- Where
- 4 sites in United States, United Kingdom
- Volunteers
- 34 people
- Sponsor
- 4D pharma plc
Aspirin, Drug Safety
Pharmacy Based Pharmacoepidemiological Observational Study With Aspirin Protect 100 mg
In this non-interventional one year study, data about overall and particularly gastrointestinal tolerability, indications, cardiovascular risk factors and compliance are collected by basic questionnaires, which are handed out by…
- Conditions
- Aspirin, Drug Safety, Effects, Longterm
- Trial name
- NCT01669824
- Testing
- Acetylsalicylic acid (Aspirin, BAYE4465)
- Where
- Germany
- Volunteers
- 4,235 people
- Sponsor
- Bayer
HIV (Human Immunodeficiency Virus), Pain
Auricular Point Acupressure for Pain
The goal of this pilot clinical trial is to learn whether auricular point acupressure (APA) can help reduce chronic musculoskeletal pain in adults age 50 and older who are living with HIV.
- Trial name
- NCT07852611
- Testing
- Auricular Point Acupressure
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Dan Song
Cancer Pain
Effects of Mobile Medicine on Cancer Patients
With the existing medical system and insufficient medical resources in China, we developed a mini program. a pain management mini app can be useful and appreciated by patients and health care professionals, making it a good…
- Trial name
- NCT05049811
- Testing
- mini program, conventional pharmaceutical care
- Volunteers
- 200 people
- Sponsor
- Fujian Cancer Hospital
Type 2 Diabetes Mellitus, Endothelial Dysfunction
Huangqi Gegen Decoction for Endothelial Function in Type 2 Diabetes at Very High ASCVD Risk
This clinical trial evaluates whether Huangqi Gegen Decoction can improve blood vessel function in adults with type 2 diabetes mellitus who are at very high risk of atherosclerotic cardiovascular disease and meet the traditional…
- Conditions
- Type 2 Diabetes Mellitus, Endothelial Dysfunction, Cardiovascular Risk
- Trial name
- NCT07775664
- Testing
- Huangqi Gegen Decoction Granules, Conventional Treatment
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Putuo Hospital, Shanghai University of Traditional Chinese Medicine
Healthy
Drug Interaction Study of Clopidogrel and Rosuvastatin
The purpose of this study is to determine if clopidogrel inhibits hepatic uptake transport of rosuvastatin clinically.
- Trial name
- NCT01469416
- Testing
- Rosuvastatin, Clopidogrel
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Intractable Epilepsy
Network Effects of Therapeutic Deep Brain Stimulation
The purpose of this study is to map the acute, short-term cortical evoked responses to thalamic electrical stimulation in persons with intractable epilepsy
- Trial name
- NCT05600738
- Testing
- RNS/DBS activation
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- The University of Texas Health Science Center, Houston
Covid-19, Drug Effect
New Treatment for COVID-19 Using Ethanol Vapor Inhalation .
Since ARDS is a major complication of COVID - 19 with subsequent formation of non-cardiogenic pulmonary edema , worsening the oxygenation of the patients and foamy and even bloody sputum formation, so the idea is to use alcohol…
- Trial name
- NCT04554433
- Testing
- Ethanol with Asprin
- Volunteers
- 80 people
- Sponsor
- Mansoura University
Urinary Incontinence, Stress
A Chinese Herbal Decoction for Stress Urinary Incontinence
The purpose of this study is to determine whether Yiqi Suoquan Tang, a Chinese Herbal decoction, is effective in the treatment of female stress urinary incontinence.
- Trial name
- NCT02616952
- Testing
- Chinese herbal therapy, Pelvic floor muscle training
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Healthy Adult Subjects, Sickle Cell Disease
Safety, Tolerability and Pharmacokinetics of FTX-6058
This is a study to evaluate the safety, tolerability and pharmacokinetics of FTX-6058 in healthy adult subjects and adult subjects with sickle cell disease (SCD).
- Trial name
- NCT04586985
- Testing
- FTX-6058 - Two Dosing Periods, FTX-6058 / Midazolam Syrup
- Where
- 2 sites in United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Fulcrum Therapeutics
Cervical Dystonia
Effect of Osteopathic Manipulative Medicine on Motor Function and Quality of Life in Cervical Dystonia
The purpose of the proposed research is to determine if Osteopathic manipulative medicine (OMM) used alone or in combination with the standard treatment of botulinum toxin intramuscular injections improves motor function and…
- Trial name
- NCT02420106
- Testing
- Osteopathic Manipulative Medicine
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- New York Institute of Technology
Human Immunodeficiency Virus Infection (HIV), HIV-1 Infection in Adults
Long-Term Real-World Evidence Study to Evaluate Effectiveness, Persistence, Adherence, Safety and Tolerability of Long-acting Cabotegravir Plus Rilpivirine.
The RELATIVITY study is a nationwide, multicenter, ambispective observational cohort evaluating the long-term effectiveness, safety, persistence, and tolerability of long-acting injectable cabotegravir plus rilpivirine (CAB+RPV…
- Trial name
- NCT07703748
- Where
- Spain
- Volunteers
- 3,346 people
- Sponsor
- FUNDACIÓN HOSPITAL UNIVERSITARIO INFANTA LEONOR Y DEL HOSPITAL UNIVERSITARIO DEL SURESTE
Gynecological Laparoscopic Surgery, General Anesthetic
Effects and Safety of Oliceridine in Anesthesia Induction:A Randomised Controlled Trial
to investigate whether oliceridine is safe and effective for induction of anesthesia by comparing henodynamic changes before and after endotracheal intubation with sufentanil
- Conditions
- Gynecological Laparoscopic Surgery, General Anesthetic, Intubation
- Trial name
- NCT07372209
- Testing
- Oliceridine, Sufentanil
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Tangshan Maternal and Child Health Hospital
Necrotic Pulp
Post Operative Pain and Level of Endotoxins With Calcium Hydroxide and Calcium Hydroxide Mixed With Chlorhexidine in Treating Necrotic Teeth
The aim of this prospective in vivo randomized clinical trial to evaluate influence of combination of calcium Hydroxide (CALCIPAST Paste, Poland) and chlorhexidine Gel 2% (Gluco-Chex 2%, Cerkamed, Poland) in comparison to calcium…
- Trial name
- NCT03009006
- Testing
- Chlorhexidine 2% gel - Calcium Hydroxide Paste - Non-Setting, Calcium Hydroxide Paste - Non-Setting
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Cairo University
COVID-19 Drug Treatment
Ivermectin Effect on SARS-CoV-2 Replication in Patients With COVID-19
In the context of COVID-19 pandemic, a report on ivermectin suppression of SARS-CoV-2 viral replication in cell cultures has been published, and the use of this medication seems to be potentially useful for the therapy.
- Trial name
- NCT04381884
- Testing
- IVERMECTIN (IVER P®) arm will receive IVM 600 µg / kg once daily plus standard care. CONTROL arm will receive standard care.
- Where
- 3 sites in Argentina
- Volunteers
- 45 people
- Sponsor
- Laboratorio Elea Phoenix S.A.
Healthy Subjects
Study to Determine the Single and Repeat Dose Pharmacokinetics, Food Effect, Proton Pump Inhibitor (PPI) Drug Interaction, Safety and Tolerability of Oral Prototype Formulations of BOS172767 in Healthy Subjects
Part 1 of the study will be conducted to provide additional information on the safety and tolerability of single doses of BOS172767 in healthy participants, to evaluate the pharmacokinetic (PK) profiles (including relative…
- Trial name
- NCT03464058
- Testing
- BOS172767 tablets, BOS172767 liquid capsules, BOS172767 micronized capsules
- Where
- United Kingdom
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Boston Pharmaceuticals
Lymphoma, Advanced Cancer
A Drug Interaction Study of Tasisulam in Patients With Advanced Cancer or Lymphoma
The purpose of this study was to assess the effect of tasisulam as an inhibitor of CYP2C9, using tolbutamide as a probe substrate. This study was to have 3 treatment periods, and continued access in an extension period.
- Trial name
- JZAR (NCT01185548)
- Testing
- Tolbutamide, Tasisulam
- Where
- 5 sites in United Kingdom
- Volunteers
- 4 people
- Sponsor
- Eli Lilly and Company
Medication Adherence, Medication Nonadherence
Collaborative Nurse-pharmacist Counseling for Self-administered Biologics
The goal of this clinical trial is to learn if nurse-pharmacist counseling can improve patient knowledge and confidence and prevent side effects in patients who start a biologic medication in-office and later continue the…
- Conditions
- Medication Adherence, Medication Nonadherence, Adverse Drug Event
- Trial name
- COLLAB (NCT05798104)
- Testing
- Collaborative nurse-pharmacist counseling
- Where
- United States
- Sponsor
- Tonia Carr
HIV Infections
Drug Interaction Study With Atazanavir Administered With and Without Ritonavir and a Cytochrome P450 Substrate Rosiglitazone
The purpose of this clinical research study is to assess the effect of Atazanavir 400 mg QD and Atazanavir/Ritonavir 300/100 mg QD at steady state on the single dose pharmacokinetics of RGZ in healthy subjects.
- Trial name
- NCT00362726
- Testing
- Rosiglitazone maleate, Atazanavir Sulphate, Atazanavir Sulphate + Rosiglitazone maleate
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Arthroscopy
Comparison the Effects of 3 Different Intraarticular Ketamine Doses on Postoperative Pain.
the aim is to compare the effects of two different doses of intraarticular ketamine on postoperative pain scores and analgesic requirements.in knee artroscopy
- Trial name
- NCT03955809
- Testing
- Ketamine 0.5, Ketamine 1, % 0.9 NaCl
- Volunteers
- 75 people
- Sponsor
- Balikesir University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.