Clinical trials: Effectiveness
Dyspepsia
A Comparison of Effectiveness of Oral Sucrolfate, Alginate and Hydrotalcide in Dispeptic Pain Treatment
Dyspepsia is a very common but non-specific complaint that may indicate a group of symptoms that can be attributed to the upper gastrointestinal system, such as epigastric discomfort, abdominal bloating or fullness, stomach upset…
- Trial name
- NCT03635372
- Testing
- Alginate, Sucralfate, Hydrotalcite
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Pamukkale University
Respiratory Distress Syndrome in Premature Infant, Bronchopulmonary Dysplasia
Efficacy of Recombinant Human Clara Cell 10 Protein (rhCC10) Administered to Premature Neonates With Respiratory Distress Syndrome
Bronchopulmonary Dysplasia (BPD) is a multi-factorial disease process that is the end result of an immature, surfactant deficient lung that has been exposed to hyperoxia, mechanical ventilation and infection.
- Trial name
- NCT01941745
- Testing
- Half normal saline, Low Dose rhCC10, High dose rhCC10
- Where
- 3 sites in United States
- Volunteers
- 88 people
- Sponsor
- Tufts Medical Center
Facial Rejuvenation
Assessment of the Safety and Efficacy of the Dermal Filler "mARG-01-17" in Facial Rejuvenation Therapy
The aim of the clinical investigation is to evaluate the performance of the mARG-01-17 dermal filler in the context of its efficacy and safety.
- Trial name
- NCT04643977
- Testing
- mARG-01-17 (mesohyal AGRIBENONE)
- Where
- Bulgaria
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mesoestetic Pharma Group S.L.
Psychological Stresses
Strengths-Based Family Psychoeducation for Youth Psychosis
The onset of Psychosis forces family members to bear a heavy burden of care. The mental well-being of the family is so complicated that it is important to relieve their psychological stresses.
- Trial name
- NCT01731977
- Testing
- Strengths-based family psychoeducation
- Where
- 4 sites in Japan
- Volunteers
- 74 people
- Sponsor
- Nagoya City University
Amyotrophic Lateral Sclerosis
Efficacy and Safety of YAM80 in Amyotrophic Lateral Sclerosis (ALS)
The efficacy and safety are evaluated when YAM80 is administered orally to the patients of Amyotrophic Lateral Sclerosis (ALS).
- Trial name
- NCT00886977
- Testing
- YAM80
- Where
- Japan
- Volunteers
- 25 people
- Sponsor
- Yoshino Neurology Clinic
Rheumatoid Arthritis
Study Evaluating Multiple Ascending Doses Of ATN-103 In Japanese Subjects With Rheumatoid Arthritis
This primary purpose of this study is to evaluate the safety, tolerability, and pharmacokinetic properties of multiple ascending doses of ATN-103 administered subcutaneously (below the skin) to Japanese subjects with active…
- Trial name
- NCT01007175
- Testing
- ATN-103 10 mg q4wks, ATN-103 30 mg q4wks, ATN-103 80 mg q4wks
- Where
- 15 sites in Japan
- Volunteers
- 60 people
- Sponsor
- Ablynx, a Sanofi company
Bipolar Disorder
A Study of Brenipatide in Adult Participants With Bipolar Disorder (RENEW-Bipolar-1)
The purpose of this study is to assess the efficacy and safety of brenipatide when administered with standard of care (SoC), compared with placebo plus SoC in delaying the worsening of bipolar disorder symptoms.
- Trial name
- NCT07286175
- Testing
- Brenipatide
- Where
- 87 sites in United States, Argentina and 6 more
- Volunteers
- 400 people
- Sponsor
- Eli Lilly and Company
Acute Myeloid Leukemia, Measurable Disease
Efficacy of Venetoclax Based Regimen in Prevention Relapse of Consecutive MRD Positive AML Patients
Measurable disease (MRD) plays an important role in the therapeutic efficacy and prognosis of acute myeloid leukemia (AML). Studies show that persistent MRD positivity after induction indicates that the patient has a higher risk…
- Trial name
- NCT05361057
- Testing
- Venetoclax, Azacitidine, Venetoclax, daunorubicin, cytarabine
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Institute of Hematology & Blood Diseases Hospital, China
Respiratory Viral Infection
Study to Assess the Safety and Efficacy of ZX-7101A for Oral Suspension in Chinese Pediatric Participants 2 to 11 Years of Age With Influenza
The goal of this phase III study is to learn if ZX-7101A for oral suspension works to treat uncomplicated influenza in Pediatric Participants aged 2 to 11 years.
- Trial name
- ZX-7101A-214 (NCT07095257)
- Testing
- ZX-7101A for oral suspension, Oseltamivir phosphate for oral suspension
- Where
- 2 sites in China
- Volunteers
- 169 people
- Sponsor
- Nanjing Zenshine Pharmaceuticals
Advanced Solid Tumor
Phase I Study of QLS1103 in Subjects With Advanced Solid Tumors
This study is a phase I, dose escalation and dose expansion study of QLS1103, to evaluate the safety, tolerability, pharmacokinetics, and preliminary efficacy of QLS1103 in subjects with advanced solid tumors.
- Trial name
- NCT05884801
- Testing
- QLS1103
- Where
- China
- Volunteers
- 148 people
- Sponsor
- Qilu Pharmaceutical Co., Ltd.
MeSH
Comparison of the Effectiveness of Sambiloto Herbs (Andrographis Paniculata) and Brisk Walking Exercise on Blood Glucose of Obese Patients
Problem Formulation 1. Does herbal medicine sambiloto affect the blood glucose levels of obese sufferers? 2. Does brisk walking affect blood glucose levels in obese sufferers? 3.
- Trial name
- NCT06520501
- Testing
- Herbal Medicine Sambiloto, Brisk Walking, Brisk Walking and Herbal Medicine Sambiloto
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitas Palangka Raya
Overactive Bladder Syndrome
Therapeutic Efficacy and Safety of Mirabegron Treatment on Patients With Overactive Bladder Syndrome in Taiwan
Recent phase III trials have confirmed the efficacy and safety of mirabegron in the treatment of overactive bladder (OAB) in Europeans, Australians, North Americans, Japanese and Asians.
- Trial name
- NCT03044912
- Testing
- mirabegron
- Where
- Taiwan
- Volunteers
- 574 people
- Sponsor
- Buddhist Tzu Chi General Hospital
Acute Myocardial Infarction
The OPTIMA-5 Trail
This study was a prospective, multicenter, randomized, controlled, excellence clinical trial. Subjects meeting the inclusion/exclusion criteria were randomly assigned 1:1 to r-SAK group or the control group (normal saline).
- Trial name
- NCT05023681
- Testing
- Recombinant Staphylokinase, normal saline
- Where
- 9 sites in China
- Volunteers
- 200 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Primary Open Angle Glaucoma, Ocular Hypertension
Efficacy of the Brand-name Latanoprost and One of Its Generic Version in Primary Open Angle Glaucoma and Ocular Hypertension
The purpose of this study is to evaluate and compare efficacy and tolerability of the brand-name latanoprost and one of its generic version in subjects with primary open angle glaucoma or ocular hypertension.
- Trial name
- NCT02047630
- Testing
- Generic latanoprost, Brand-name latanoprost
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- CHU de Quebec-Universite Laval
High-Risk Acute Myeloid Leukemia
Clinical Study to Evaluate the Safety and Efficacy of γδ T Cells for the Prevention of Relapse After Allogeneic Transplantation in Patients With High-risk Acute Myeloid Leukemia
This is an investigator-initiated clinical trial evaluating the safety and efficacy of allogeneic γδ T cell infusion for relapse prevention in high-risk acute myeloid leukemia patients after transplantation.
- Trial name
- NCT07237230
- Testing
- allogeneic γδ T cell infusion
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Donghua Zhang
Pregnant Women, Pregnant Women and Their Offspring
Effectiveness of MMS Compared With IFS Among Pregnant Women in Bangladesh: an Experimental Study
Background Maternal undernutrition and micronutrient deficiencies remain highly prevalent in Bangladesh and contribute to maternal anaemia, low birth weight, preterm birth, and adverse neonatal outcomes.
- Trial name
- NCT07540130
- Testing
- Multiple micronutrient supplementation
- Where
- Bangladesh
- Volunteers
- 667 people
- Sponsor
- National Institute of Neurosciences and Hospital, Dhaka
Breast Cancer
To Evaluate the Efficacy and Safety of Capecitabine Prior to Surgery in Women With Breast Cancer
This study will evaluate the efficacy and safety of treatment with oral capecitabine or intravenous (IV) 5-fluorouracil (5-FU), in combination with epirubicin and cyclophosphamide, prior to surgery in participants with breast…
- Trial name
- NCT02846428
- Testing
- 5-Fluorouracil, Capecitabine, Cyclophosphamide
- Where
- 21 sites in France
- Volunteers
- 182 people
- Sponsor
- Hoffmann-La Roche
Advanced Esophageal Squamous Cell Carcinoma
A Study of Simmitinib Plus Irinotecan in Advanced Esophageal Squamous Cell Carcinoma
To evaluate the safety and efficacy of simmitinib plus irinotecan liposome in the treatment of advanced esophageal squamous cell carcinoma, and to evaluate the PK of the drug and the correlation between biomarkers and clinical…
- Trial name
- NCT06512428
- Testing
- simmitinib plus irinotecan liposome, irinotecan liposome, irinotecan
- Where
- China
- Volunteers
- 138 people
- Sponsor
- Shanghai Runshi Pharmaceutical Technology Co., Ltd
Moderate Alzheimer's Disease
Efficacy Study of a ZT-1 Implant in Patients Suffering From Alzheimer's Disease
Alzheimer's disease is characterised by memory loss and difficulties with thinking. These problems may be due to a deficiency in a brain chemical called acetylcholine. Acetylcholine helps transmit messages between nerve cells.
- Trial name
- BRAINz (NCT00423228)
- Testing
- ZT-1, Donepezil
- Where
- 28 sites in Australia, Canada and 1 more
- Volunteers
- 228 people
- Sponsor
- Debiopharm International SA
Coronary Artery Disease
Study to Evaluate the Safety and Efficacy of Humacyte's Coronary Tissue Engineered Vessel (CTEV) in Patients With Coronary Artery Disease Requiring Coronary Artery Bypass Grafting (CABG)
The goal of this study is to assess safety and efficacy of Humacyte's coronary tissue engineered vessel (CTEV) used as a bypass conduit in patients requiring multi vessel coronary artery bypass grafting (CABG).
- Trial name
- NCT07730528
- Testing
- Humacyte Coronary Tissue Engineered Vessel (CTEV)
- Volunteers
- 10 people
- Sponsor
- Humacyte, Inc.
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.