Clinical trials: Effectiveness
Male Pattern Hair Loss, Androgenetic Alopecia
Laser Assisted Delivery of Minoxidil in Androgenetic Alopecia
The objective of this study is to evaluate the safety and efficacy of fractionated ablative 10,600nm CO2 laser assisted delivery of 2% minoxidil solution in the treatment of MPHL.
- Conditions
- Male Pattern Hair Loss, Androgenetic Alopecia, Male Pattern Baldness
- Trial name
- NCT03852992
- Testing
- Post-Laser Minoxidil 2%, At-Home Minoxidil 5%, Laser
- Where
- United States
- Sponsor
- University of Minnesota
Graft vs Host Disease
Research Study of Visilizumab for Treatment of Acute Graft Versus Host Disease
The purpose of this Phase I/II, open-label, dose-escalation study is to evaluate an investigational monoclonal antibody administered as a first-line therapy to patients with acute, Grade II, III, or IV graft-versus-host disease…
- Trial name
- NCT00032292
- Testing
- Visilizumab
- Where
- 7 sites in United States
- Volunteers
- 34 people
- Sponsor
- Facet Biotech
Locally Advanced Gastric Cancer
Carrelizumab (PD-1) Combined With Chemotherapy in Neoadjuvant Treatment of Locally Advanced Gastric Cancer
This is a single-arm, open, exploratory clinical study to evaluate the efficacy of carrelizumab (PD-1) combined with chemotherapy (SOX/XELOX) as neoadjuvant therapy and to observe the changes of tumor immune microenvironment in…
- Trial name
- NCT05545436
- Testing
- Camrelizumab + SOX (oxaliplatin + Teggio) /XELOX (oxaliplatin + capecitabine )
- Where
- China
- Volunteers
- 34 people
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
Systemic Scleroderma
Sildenafil Effect on Digital Ulcer Healing in sClerodErma SEDUCE STUDY
Digital ulcers (DUs) are an expression of the microangiopathy in patients with scleroderma (SSc). DUs lead to pain and impaired hand use. DUs remain a severe complication for many patients and effective therapy remains elusive.
- Trial name
- SEDUCE (NCT01295736)
- Testing
- Sildenafil
- Where
- 24 sites in France
- Volunteers
- 84 people
- Sponsor
- University Hospital, Lille
Hypertension
Effectiveness of SMS Text Reminders to Improve Blood Pressure Among Patients With Hypertension
Objective: To test the primary hypothesis that SMS text messages delivered to patients via mobile phone can improve blood pressure within 12 weeks compared to usual care Design: Parallel group, randomized, controlled trial; the…
- Trial name
- NCT01255436
- Testing
- SMS text reminders, Usual Care
- Where
- Philippines
- Volunteers
- 700 people
- Sponsor
- University of the Philippines
Plasmodium Falciparum Malaria
A Phase I/IIa Sporozoite Challenge Study to Assess the Efficacy of Candidate Combination Malaria Vaccine Approaches Using the ChAd63 and MVA Vectors Encoding the Antigens ME-TRAP, CS and AMA1
This is an open label, multi-centre phase I/IIa sporozoite-challenge trial to assess the safety, immunogenicity and efficacy of two combination ChAd63-MVA heterologous prime-boost vaccination regimens.
- Trial name
- NCT01739036
- Testing
- ChAd63 CS/ME-TRAP, MVA CS/ME-TRAP, ChAd63 CS/ME-TRAP/AMA1
- Where
- 3 sites in United Kingdom
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Drug-Induced Liver Injury, Cholestatic Liver Injury
A Randomized,Double-blind, Placebo Controlled, Multicenter Study to Evaluate the Safety and Efficacy of MT2004 Capsule in DILI Subjects
The goal of this randomized, double-blind, placebo controlled, Multicenter Phase II clinical trial is to initially evaluate the Safety and Efficacy of MT2004 Capsule in Cholestatic and Mixed drug induced liver injury (DILI)…
- Conditions
- Drug-Induced Liver Injury, Cholestatic Liver Injury, Mixed Liver Injury
- Trial name
- NCT06019936
- Testing
- MT2004 Capsule
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Xi'An Aolitai Pharmaceutical Technology Co Ltd
Hyponatremia, Ascites
Tolvaptan for Hyponatremia in Cirrhotic Patients With Ascites
The purpose of the study is to investigate the efficacy and safety for the management of hyponatremia and ascites in patients with liver cirrhosis.
- Trial name
- TONIC (NCT01716611)
- Testing
- Tolvaptan
- Where
- South Korea
- Volunteers
- 105 people
- Sponsor
- Konkuk University Medical Center
Immunization Coverage, Vaccination
Increasing Measles Vaccination Coverage Through Supplementation With an SQ-LNS Incentive in Children Aged 6-23 Months
Provision of SQ-LNS also holds promise in incentivizing vaccination as well as other health services. The investigators will estimate 1) the effectiveness of a SQ-LNS mass supplementation program added to routine immunization…
- Conditions
- Immunization Coverage, Vaccination, Nutrition
- Trial name
- NCT06387511
- Testing
- Small-quantity lipid-based nutrition supplements (SQ-LNS) NutriVax, Sensitization on vaccination and on Infant and Young Child Feeding (IYCF) practices
- Where
- Nigeria
- Volunteers
- 3,814 people, healthy volunteers welcome
- Sponsor
- Alliance for International Medical Action
Esophageal Neoplasms
Efficacy and Safety of Apatinib for Recurrent or Metastatic Esophageal Squamous Cell Carcinoma
There is no standard treatment strategy for recurrent or metastatic esophageal squamous cell carcinoma patients now, especially after the second-line treatment.
- Trial name
- NCT03274011
- Testing
- Apatinib
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Fudan University
Gastric Adenocarcinoma
Using Genetic Polymorphisms to Predict the Efficacy and Toxicity - A Gastric Adenocarcinoma Study
This is an open-label, non-comparative phase II study of sequential capecitabine plus oxaliplatin followed by docetaxel plus capecitabine in patients with unresectable gastric adenocarcinoma.
- Trial name
- NCT01558011
- Testing
- Capecitabine, Oxaliplatin, Docetaxel
- Where
- Taiwan
- Volunteers
- 51 people
- Sponsor
- National Health Research Institutes, Taiwan
Stroke
Metacognitive-Strategy Training in Sub-Acute Stroke
The long-term goal of this research is to improve activity performance and reduce motor impairment in individuals with stroke. Contemporary stroke rehabilitation focuses on remediation of post-stroke impairments with a false…
- Trial name
- NCT04099511
- Testing
- Usual Care Occupational Therapy-Outpatient, Cognitive Orientation to daily Occupational Performance
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Missouri-Columbia
Pulmonary Disease, Chronic Obstructive
Co-administration of Olodaterol Respimat® and Tiotropium Handihaler®
The overall objective of this study is to assess efficacy and safety of 12 weeks, once daily, orally inhaled co-administration of olodaterol 5 µg (delivered by the Respimat® Inhaler) and tiotropium (delivered by the Handihaler®…
- Trial name
- NCT01694771
- Testing
- Tiotropium, Olodaterol
- Where
- 90 sites in United States
- Volunteers
- 1,134 people
- Sponsor
- Boehringer Ingelheim
Chronic Pelvic Pain
Clinical Observation on the Efficacy of Acupoint Force Therapy Devices in the Intervention of Chronic Pelvic Pain
The present study is a prospective,single-center, single-arm, pre-post control clinical trial conducted at Peking University Third Hospital.
- Trial name
- NCT07841171
- Testing
- EMMA Robot-assisted Tuina
- Volunteers
- 20 people
- Sponsor
- Peking University Third Hospital
Lumbar Erector Spinae Plane Block, Pericapsular Nerve Group Block (PENG Block)
Combined Lumbar Erector Spinae Plane Block and Pericapsular Nerve Group Block in Patients Undergoing Hip Surgeries
The investigators are going to evaluate the postoperative analgesic efficacy of combined LESPB and PENG block after hip surgeries.
- Trial name
- NCT05930171
- Testing
- Ultrasound guided L-ESPB and PENG block using Bupivacaine, Postoperative conventional analgesia in form of Acetaminophen
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Telangectasia, Reticular Veins
Foam and Liquid Sclerotherapy With or Without Herbal Gel for Small Vein Treatment
Telangiectasias (spider veins) and reticular veins represent early and common manifestations of chronic venous insufficiency . Telangiectasias are dilated intradermal venules or capillaries less than 1 mm in diameter and…
- Trial name
- ELF-HTR (NCT07162844)
- Testing
- Liquid sclerotherapy in telangectasia and reticular veins without application of herbal gel post procedure, Liquid sclerotherapy in telangectasia and reticular veins wit application of herbal gel post procedure, foam sclerotherapy in telangectasia and reticular veins without application of herbal gel post procedure
- Where
- Egypt
- Volunteers
- 508 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Immune Thrombocytopenia (ITP)
A Phase 1/2 Study of ESG206 in Patients With Primary Immune Thrombocytopenia
This is a multicenter, open-label Phase1/2 study aimed at evaluating the safety, tolerability, pharmacokinetic (PK) profile, pharmacodynamics (PD), immunogenicity, and preliminary efficacy of ESG206.
- Trial name
- NCT06853444
- Testing
- ESG206
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Shanghai Escugen Biotechnology Co., Ltd
Rheumatoid Arthritis
A Prospective, Non-Interventional Study of RoActemra/Actemra (Tocilizumab) in Patients With Moderate to Severe Active Rheumatoid Arthritis
This prospective, observational study will evaluate the efficacy, safety and tolerability of RoActemra/Actemra (tocilizumab) in patients with moderate to severe active rheumatoid arthritis who have had an inadequate response or…
- Trial name
- NCT01770834
- Where
- 12 sites in Kuwait, Lebanon and 2 more
- Volunteers
- 100 people
- Sponsor
- Hoffmann-La Roche
Acute Muscle Pain
Evaluation of Efficacy and Safety of SPARC1401 in Acute Low Back Pain
A phase 2 randomized clinical trial to evaluate efficacy and safety of SPARC1401 at three dose levels in patients with acute low back pain
- Trial name
- NCT02887534
- Testing
- SPARC1401-low dose, SPARC1401-mid dose, SPARC1401-high dose
- Sponsor
- Sun Pharma Advanced Research Company Limited
Hepatocellular Carcinoma
A Study of Anlotinib in Patients With Hepatocellular Carcinoma
To assess the primary effects and safety of Anlotinib with placebo in patients with Hepatocellular Carcinoma(HCC).
- Trial name
- ALTER0802 (NCT02809534)
- Testing
- Anlotinib
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
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