Clinical trials: Effects of Chemotherapy
Breast Cancer, Colorectal Cancer
Effect of Kefir on Symptom Management and Quality of Life in Oncology
This study was planned as a randomized controlled prospective experimental study to determine the effect of kefir on symptom management and quality of life in oncology patients receiving chemotherapy.
- Trial name
- NCT06517420
- Testing
- kefir consumption
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Izmir Bakircay University
Metastatic Colorectal Cancer (CRC), Volunteer Subjects
Evaluation of the Effect of Adapted Physical Activity on the Modification of Lipid Metabolism During Chemotherapy for Metastatic COLorectal Cancer
APACOL is a pilot, bicentric, randomised, open-label, prospective, category 2 study. The presence of colon cancer modifies blood lipid parameters which are likely to have an impact on the efficacy of anti-cancer treatments.
- Trial name
- APACOL (NCT06944548)
- Testing
- Lipidomic analyses, Adapted physical activity program
- Where
- 2 sites in France
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Centre Georges Francois Leclerc
Glioblastoma Multiforme
Usefulness of Therapy Monitoring by Means of [(18)F]Fluoroethyltyrosine-Positron Emission Tomography (FET-PET) in Glioblastoma Multiforme Patients
The aim of this study is to establish FET-PET as an additional therapy assessment parameter in patients diagnosed with a glioblastoma multiforme receiving radiochemotherapy and adjuvant chemotherapy after previous resection or…
- Trial name
- NCT01089868
- Where
- 3 sites in Germany
- Volunteers
- 79 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Glioma (Any Grade) in the Brain
Study on The Sensitizing Effect of Sonodynamic Therapy on The Treatment of Brainstem Glioma With Radiotherapy and Chemotherapy and Survival Analysis
1.Brief Introduction to the Research Background: You are invited to participate in a clinical study initiated by the First Affiliated Hospital of Zhengzhou University and chaired by Professor Zheng Yingjuan at our center.
- Trial name
- NCT06999148
- Testing
- Sonodynamictherapy, Radiotherapy plus temozolomide
- Where
- China
- Volunteers
- 216 people
- Sponsor
- Yingjuan Zheng
Breast Cancer, Cognitive Dysfunction
eHealth Interventions for Breast Cancer Cognitive Impairment
This study investigates the effectiveness of integrating a cognitive rehabilitation module into a digital psychosocial intervention for recently diagnosed breast cancer patients.
- Trial name
- ICOgnition (NCT06103318)
- Testing
- ICOgnition
- Volunteers
- 176 people
- Sponsor
- Institut Català d'Oncologia
Attention Deficit Disorder, Attention Deficit Disorder (ADD)
The Primary Objective of This Study is to Determine Whether Positively Framed Information (PFI) on Side Effects, Compared to Negatively Framed and Extensive Information (NFI) Can Reduce the Number and Severity of Reported Adverse Events Caused by ADHD Medication in Children Aged 7 to 17 Years.
The goal of this randomized controlled care evaluation is to determine whether positively framed and concise information (PFI), compared to negatively framed and extensive information (NFI) about adverse events can reduce the…
- Conditions
- Attention Deficit Disorder, Attention Deficit Disorder (ADD), Attention Deficit Disorder with Hyperactivity, ADHD
- Trial name
- NOVA (NCT06797570)
- Testing
- Communication Strategy for Side Effect Counseling in ADHD Treatment
- Volunteers
- 130 people
- Sponsor
- St. Antonius Hospital
Tongue Cancer, Chemotherapy Effect
A Study of Tongue Conservation Surgery for Oral Tongue Cancer
This is an open-label, non-comparative phase II clinical trial to assess efficacy and safety of tongue conservation treatment with sequential induction chemotherapy, tongue conservation surgery and postoperative concurrent…
- Conditions
- Tongue Cancer, Chemotherapy Effect, Surgery
- Trial name
- NCT03161548
- Testing
- Induction chemotherapy, Tongue conservation surgery, postoperative CCRT
- Volunteers
- 23 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Prostate Cancer, Chemotherapy Effect
Neoadjuvant Chemo-hormonal Therapy Combined With Radical Prostatectomy for Locally Advanced Prostate Cancer
To evaluate of the value of radical prostatectomy and extended pelvic lymph node dissection in locally advanced prostate cancer after neoadjuvant hormonal therapy with or without docetaxel chemotherapy.
- Conditions
- Prostate Cancer, Chemotherapy Effect, Hormone Sensitive Prostate Cancer, Locally Advanced Prostate Carcinoma
- Trial name
- NCT04220398
- Testing
- Neoadjuvant chemotherapy combined with hormone therapy, Neoadjuvant hormone therapy, Radical Prostatectomy (RP)+ extended lymph node dissection
- Volunteers
- 475 people
- Sponsor
- RenJi Hospital
Ovarian Cancer
The Effects Of Yoga On Quality Of Life Among A Population Of Ovarian/ Fallopian Tube/ Primary Peritoneal Cancer Patients Receiving Chemotherapy: A Feasibility Study
This is a pilot study to establish the feasibility of an eight-week yoga intervention and to estimate the effect size on QoL in female patients with ovarian, fallopian tube and primary peritoneal malignancies receiving…
- Trial name
- NCT01743547
- Testing
- Yoga
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Northwestern University
Breast Cancer, Colon Cancer
The Effect of Aerobic Exercise on Selective Biomarkers of Patients With Cancer
This study is a single-blinded, prospective, controlled trial aiming to evaluate the effect of supervised aerobic exercise on adipokine and myokine biomarkers in patients with breast or colon cancer during their systemic…
- Conditions
- Breast Cancer, Colon Cancer, Chemotherapy Effect
- Trial name
- NCT07048847
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Izmir Bakircay University
Chemotherapy-induced Peripheral Neuropathy
The Preliminary Effects of Henna on CIPN
Chemotherapy-induced peripheral neuropathy (CIPN) is one of the most common long-term toxicities of chemotherapy. Though, CIPN is one of the common symptoms encountered by oncology nurses in care of patients.
- Trial name
- NCT04201587
- Testing
- Henna application
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Neoplasm Metastases
A Study to Assess the Potential Effects of Ketoconazole on the Pharmacokinetics of Trabectedin in Patients With Advanced Malignancies
The purpose of this study is to evaluate the potential effects of ketoconazole on blood levels of trabectedin after administration to patients with advanced malignancies.
- Trial name
- NCT01267084
- Testing
- Trabectedin, Ketoconazole, Dexamethasone or equivalent steroid
- Where
- 2 sites in Belgium
- Volunteers
- 12 people
- Sponsor
- Janssen Research & Development, LLC
Pancreatic Cancer, Chemotherapy Effect
The Safety and Efficacy of the Combination of Raltitrexed for Injection and Nab-Paclitaxel in Advanced Pancreatic Cancer
The present study is intended to investigate the safety and efficacy of the patients with confirmed advanced pancreatic cancer after treating with the combination of raltitrexed for injection and nab-paclitaxel.
- Trial name
- NCT04581876
- Testing
- raltitrexed for injection, nab-paclitaxel
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Fudan University
Upper Abdominal Malignancies, Upper Gastrointestinal Cancer
Comparison of CT-Guided Celiac Plexus Neurolysis and Pharmacotherapy
After enrolment, patients were randomly assigned to two groups by means of a lottery procedure, whereby each patient blindly chose one of two labelled slips, resulting in group assignment to receive.
- Trial name
- NCT07761650
- Testing
- CT-guided celiac plexus neurolysis, Standard pharmacotherapy
- Where
- Pakistan
- Volunteers
- 110 people
- Sponsor
- Mayo Hospital Lahore
Chemotherapy- and/or Radiation-induced Oral Mucositis
A Trial of Episil® Oral Liquid in Cancer Patients Suffering From Chemotherapy- and/or Radiation-induced Oral Mucositis
This is a randomized, multi-center, single-use, active-controlled, two-stage open study of episil®. The purpose of this study is to assess the local analgesic effect of episil® in cancer patients suffering from chemotherapy…
- Trial name
- NCT03546985
- Testing
- episil®, Kang Su
- Where
- 7 sites in China
- Volunteers
- 60 people
- Sponsor
- Solasia Pharma K.K.
Testicular Cancer
Physical Activity and Testicular Cancer
The purpose of this study is to determine the feasibility and effect of a program including information, counseling and an individualized physical activity program on physical and psychological health during and after…
- Trial name
- NCT01749774
- Testing
- Physical activity counseling
- Where
- Norway
- Volunteers
- 13 people
- Sponsor
- Oslo University Hospital
Breast Cancer
Study to Determine Treatment Effects of Denosumab in Patients With Breast Cancer Receiving Aromatase Inhibitor Therapy
The purpose of this study is to determine whether denosumab compared to placebo, will reduce the rate of first clinical fracture in women with non-metastatic breast cancer receiving (non-steroidal) aromatase inhibitor therapy.
- Trial name
- NCT00556374
- Testing
- Denosumab, Non-steroidal aromatase inhibitor therapy, Zoledronic Acid
- Where
- 46 sites in Austria, Sweden
- Volunteers
- 3,420 people
- Sponsor
- Amgen
Chemotherapy Effect
Perioperative Oxaliplatin With S-1 Combined H. Pylori Eradication in the Management of Locally Advanced Gastric Cancer
This study focuses on patients with H. pylori-positive resectable locally advanced adenocarcinoma of the gastric and oesophagogastric junction. It evaluates the perioperative oxaliplatin with S-1 (SOX) combined H.
- Trial name
- NCT06510010
- Testing
- Oxaliplatin With S-1 (SOX) Combined H. Pylori Eradication (Amoxicillin + clarithromycin + omeprazole + colloidal bismuth subcitrate), Oxaliplatin With S-1 （SOX）
- Where
- China
- Volunteers
- 198 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Diabetes, Depression
Treatment of Diabetes and Depression in Hispanics and African Americans and Its Effect on A1c and Quality of Life.
This proposed study will test the following hypothesis: Treating depression in Hispanics and African Americans with diabetes will improve their HbA1c and quality of life while on intervention and six months after intervention.
- Trial name
- NCT00624013
- Testing
- sertraline
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Charles Drew University of Medicine and Science
Pediatric Cancer
The Effect of Occupation-Based Nursing Program Applied to Pediatric Oncology Patients
Nurses can include the child in their occupational activities by using the therapeutic communication techniques they have learned during their education.
- Trial name
- NCT04709653
- Testing
- Occupation-based nursing program, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Akdeniz University