Clinical trials: Effects of Heat, open to volunteers
Kidney Calculi, Ureteral Calculi
Impact of Humid-Heat on Gut-Tryptophan-Stone Pathway
Investigating the differences in gut microbiota composition and tryptophan metabolite levels between kidney stone patients and healthy individuals, with special focus on: 1.
- Trial name
- NCT07043374
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Eosinophilic Esophagitis
Pediatric Eosinophilic Esophagitis (pedEoE): Effect of Allergen Heat Denaturation on EoE Remission: a Pilot Trial
The objective of the study is to study whether the introduction of heated food products (more specifically heated hen's egg and/or cow's milk) in children with EoE would be possible without re-occurrence of the eosinophilic…
- Trial name
- NCT06381219
- Testing
- Implementation of cow's milk in decreasingly heated forms, Implementation of hen's egg in decreasingly heated forms
- Where
- Belgium
- Volunteers
- 36 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Vaginitis Bacterial, Inflammation, Ear
Effect of Lactobacillus Johnsonii or White Pomegranate Extract on the Vaginal Health
The goal of this clinical trial is to explore the effect of Lactobacillus johnsonii and white pomegranate extract on female bacterial status, it aims to answer are: Evaluate Lactobacillus johnsonii TCI250 probiotics or white…
- Trial name
- NCT06069531
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- Chung Shan Medical University
Acute Low Back Pain
The Palliative Effect of TENS-WAA on 'Capsaicin/Heat' Induced Acute Lower Back Pain: a Self-controlled Clinical Study
Acute lower back pain is a common condition that occurs in all age groups, and most people will experience acute lower back pain at least once in their lives.
- Trial name
- NCT06944665
- Testing
- Transcutaneous Electrical Nerve Stimulation based on Wrist-Ankle Acupuncture theory
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Xiaonan Huang
Cold-water Immersion, High Heat Sauna
Thermodynamic Exposure and Sleep in Military Cadets
This pilot study investigates the effects of cold-water immersion, traditional sauna use, and their combination on sleep architecture and psychological health in military cadets.
- Conditions
- Cold-water Immersion, High Heat Sauna, Combination of Cold-water Immersion and High Heat Sauna
- Trial name
- NCT07201935
- Testing
- Cold Water Immersion, High Heat Sauna
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Cholelithiasis
Electrosurgical Patterns and Learning Curve in Elective Laparoscopic Cholecystectomy
This prospective observational study will examine how electrosurgical activation patterns during elective laparoscopic cholecystectomy are associated with surgeon experience and intraoperative difficulty.
- Trial name
- ELECTRO-LC (NCT07888491)
- Testing
- Elective laparoscopic cholecystectomy
- Where
- Croatia
- Volunteers
- 165 people
- Sponsor
- University Hospital of Split
Physical Inactivity, Vascular Dysfunction
Heat Therapy During Reduced Physical Activity
The purpose of this randomized controlled trial is to determine whether daily Finnish dry sauna therapy attenuates the adverse cardiovascular, muscular, and metabolic effects of seven days of experimentally reduced physical…
- Conditions
- Physical Inactivity, Vascular Dysfunction, Skeletal Muscle Atrophy
- Trial name
- HEAT-RPA (NCT07847424)
- Testing
- Sauna, Reduced Physical Activity
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Brigham Young University
Skin Cancer, Heat Tolerance
Title: ICARUS - Psycho-physiological Profiling of Low and High Heat-resilient Individuals
The escalating environmental heat-stress associated with global warming is a societal challenge with large and potential harmful consequences for humans.
- Conditions
- Skin Cancer, Heat Tolerance, Heat-related Illness, Hyperthermia
- Trial name
- ICARUS (NCT07510061)
- Testing
- Controlled Heat and Ultraviolet Radiation Exposure Protocol
- Where
- 2 sites in Denmark, Greece
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Heat Stroke
Study of Thermoregulation in Exercise Heat Stroke in the Military Environment
The EXPLO-MITO study is an ancillary study from the main EXPLO-CCE study (NCT04593316; IDRCB: 2020-A01967-32). The Heat Tolerance Test (HTT) is a physiological exploration that has several advantages for use in research and…
- Trial name
- EXPLO-MITO (NCT05847465)
- Testing
- Bike stress test, Heat Tolerance Test, Heat nociception test
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Hyperthermia
Rapid Cool: Heat Stroke Treatment
Hot climates such as in Phoenix, AZ commonly have individuals experiencing heat stroke, a life-threatening medical emergency. The dangerously high body temperature can result in death if not treated immediately with rapid body…
- Trial name
- NCT07743619
- Testing
- Recirculated water, Phoenix protocol
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Smoking ( Cigarette), Smoking (Tobacco) Addiction
Smoking Cessation With Wearables to Improve General, Oral Health and Quality of Life
Tobacco smoking remains one of the leading preventable causes of disease, disability, and premature death worldwide. According to the World Health Organization, tobacco use is responsible for more than eight million deaths each…
- Conditions
- Smoking ( Cigarette), Smoking (Tobacco) Addiction, Smoking Behaviors, Smoking Cessation
- Trial name
- Wear-Smile (NCT07593742)
- Testing
- Telemedicine-Based Smoking Cessation Program, Conventional Smoking Cessation Behavioral Program
- Volunteers
- 102 people
- Sponsor
- University of Salerno
Heat Strain, Healthy Volunteer Study
The Kidney's Response to Exercise in Heat, and the Impact of Vitamin B3 on This Response
The goal of this clinical trial is to learn about the processes occurring in the kidneys while under heat stress in healthy volunteers.
- Conditions
- Heat Strain, Healthy Volunteer Study, Kidney Dysfunction
- Trial name
- NCT06983730
- Testing
- Vitamin B3
- Where
- 2 sites in United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Intermediate AMD
A Clinical Trial Evaluating the Safety and Efficacy of a New Light Combination Therapy Addressing Intermediate AMD
The proposed clinical investigation wants primary to validate the safety of the innovative light therapy approach and in second priority provide insight and confirmations on therapeutic effect.
- Trial name
- retinaSEES-PoC (NCT06557369)
- Testing
- reSEES
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Oculox Technologies SA
Cutaneous Metastatic Melanoma
Intratumoral Targeted Hyperthermia Therapy (THT) for Cutaneous Metastatic Melanoma
This device phase I/II, first in human, early feasibility study (EFS), open-label, single-arm trial aims to evaluate the safety, tolerability, and preliminary efficacy of Gold Nanorod (GNR)-enabled sub-ablative targeted…
- Trial name
- NCT06870994
- Testing
- Targeted Hyperthermia Therapy
- Volunteers
- 10 people
- Sponsor
- Sona Nanotech Inc
Aging
Identification of Critical Thermal Environments for Aged Adults
This study evaluates critical environmental limits (temperature and humidity) above which older adults are unable to effectively thermoregulate.
- Trial name
- NCT04284397
- Testing
- Low dose ASA, Control
- Where
- United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Penn State University
Depression, Selective Serotonin Reuptake Inhibitor
Impact of Depression on Thermoregulation
The purpose of this study is to determine if, compared to non-depressed adults, differences exist in skin blood flow and sweating responses to passive heat stress in adults with clinically diagnosed depression, those with…
- Trial name
- NCT06805851
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Penn State University
General Population, no Specific Condition
Heat Waves, Urban Heat Islands, and Wellbeing and Health: a Mobile Sensing Approach
The first objective of H3Sensing is to investigate outdoor environmental, building, dwelling, situational, and behavioral determinants of objectively assessed personal heat stress over daily movements during warm periods.
- Trial name
- H3Sensing (NCT06850025)
- Where
- France
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Depression, Mood Disorders
Cold and Heat Investigation to Lower Levels of Depression
This study will recruit 112 medically healthy adults (aged 18-65) currently experiencing depressive symptoms to be randomized to receive either a single Whole Body Hyperthermia (heat therapy) treatment or a Whole Body…
- Conditions
- Depression, Mood Disorders, Healthy (Controls)
- Trial name
- CHILL'D (NCT06263738)
- Testing
- Whole Body Hyperthermia, Cold Water Plunge
- Where
- United States
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Barry Sandler
Head and Neck Cancer, Oropharyngeal Carcinoma
Thermotherapy for Head and Neck Cancer Patients
This phase I, single-center study evaluates the safety, tolerability, and recommended phase II dose (RP2D) of mild hyperthermia (thermotherapy) when added to standard-of-care treatment in patients with locally advanced head and…
- Conditions
- Head and Neck Cancer, Oropharyngeal Carcinoma, Hypopharyngeal Carcinoma, Laryngeal Carcinoma
- Trial name
- TANCAP-I (NCT07690618)
- Testing
- Thermotherapy, Radiotherapy, Concurrent chemoradiation
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Erasmus Medical Center
PAD, PAD - Peripheral Arterial Disease
Home-Based Lower-Extremity Heat Therapy for Walking Function in Peripheral Artery Disease
Lower-extremity peripheral artery disease is associated with impaired walking ability, reduced lower-extremity function, and decreased quality of life.
- Trial name
- NCT07653243
- Testing
- Lower-Extremity Heat Therapy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Aquilo Sports, LLC