Clinical trials: Egg Allergy
Food Allergy, Egg Allergy
Efficacy and Safety of Egg Ladders in Children With IgE-Mediated Hen's Egg Protein Allergy
Hen's Egg Allergy is one of the most common food allergies in early childhood. The first-line treatment is the elimination of hen's egg proteins from the child's or maternal diet.
- Conditions
- Food Allergy, Egg Allergy, Hen Egg Allergy
- Trial name
- NCT07040111
- Testing
- oral food challenge (OFC)
- Where
- 2 sites in Poland
- Volunteers
- 94 people
- Sponsor
- Medical University of Warsaw
Food Allergy
ADP101 for Oral Immunotherapy in Food-Allergic Children and Adults
The purpose of this study is to assess the efficacy and safety of ADP101 in food allergic children and adults.
- Trial name
- NCT04856865
- Testing
- Low dose ADP101, High dose ADP101
- Where
- 15 sites in United States
- Volunteers
- 73 people
- Sponsor
- Alladapt Immunotherapeutics, Inc.
Allergy
Follow up of Patients After Oral Immunotherapy for Cow's Milk, Eggs and Peanuts
Food allergy is a potentially life threatening condition. The current practice consists of elimination diet and injectable epinephrine in case of a reaction.
- Trial name
- OIT followup (NCT01999387)
- Testing
- Allergenic food
- Where
- Israel
- Volunteers
- 500 people
- Sponsor
- Assaf-Harofeh Medical Center
Food Allergy, Food Allergy in Infants
Basophil Activation Test to Diagnose Food Allergy
The BAT II Study is a cross-sectional diagnostic study in which children with suspected IgE-mediated allergy to foods (namely cow's milk, egg, sesame and cashew), as defined by a history of an immediate-type allergic reaction to…
- Conditions
- Food Allergy, Food Allergy in Infants, Food Allergy in Children, Food Allergen Sensitisation
- Trial name
- BAT2 (NCT03309488)
- Testing
- Oral food challenge
- Where
- United Kingdom
- Volunteers
- 600 people
- Sponsor
- King's College London
IgE-Mediated Food Allergy, Peanut Allergy
A 52-week Study of Remibrutinib in IgE-mediated Food Allergy
The purpose of this Phase III study is to evaluate the clinical efficacy and safety of remibrutinib in participants with peanut, or cow's milk ("milk", cooked and uncooked) or hen's egg ("egg", cooked and uncooked) immunoglobulin…
- Conditions
- IgE-Mediated Food Allergy, Peanut Allergy, Cow Milk Allergy, Egg Allergy
- Trial name
- NCT07768371
- Testing
- Remibrutinib
- Where
- 18 sites in United States
- Volunteers
- 576 people
- Sponsor
- Novartis Pharmaceuticals
Egg Allergy, Egg Hypersensitivity
Oral Immunotherapy for Children With Egg Allergy
This clinical trial aims to investigate if oral immunotherapy can help children with egg allergy tolerate eggs. Children aged 6-18 months can take part in the trial.
- Conditions
- Egg Allergy, Egg Hypersensitivity, Food Allergy in Children, Food Allergies
- Trial name
- NCT07888439
- Testing
- Oral immunotherapy with egg
- Where
- 5 sites in Denmark
- Volunteers
- 76 people
- Sponsor
- Laura Ozer Kettner
Peanut Allergy, Milk Allergy
The Utility of Food-Specific IgE Measured With the IMMULITE 2000 Assay to Predict Symptomatic Food Allergy
Food allergy is on the rise within the pediatric population. Having food allergy can cause medical, nutritional and psychological issues in those who suffer with it.
- Conditions
- Peanut Allergy, Milk Allergy, Egg Allergy
- Trial name
- IMMULITE 2000 (NCT01950533)
- Testing
- Oral food challenge
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- National Jewish Health
Food Allergy in Children, Milk Allergy
Comparison Between a Rush and a Conventional Oral Immunotherapy Protocol to Treat Cow's Milk and Hen´s Egg Allergy. CompITO Study
This study investigates the efficacy and safety of two different OIT schemes to treat milk and egg allergic children
- Conditions
- Food Allergy in Children, Milk Allergy, Egg Allergy
- Trial name
- compITO (NCT06976775)
- Testing
- "Rush" regimen, "Conventional" regimen
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Pablo Rodríguez del Rio
Food Allergies, Peanut Allergies
A Long Term, Observational Follow-Up Study of Children and Young People Who Underwent an 18-Month Course of Oral Immunotherapy Treatment for Peanut, Egg or Milk Allergy (5-15 Years Post-Treatment)
The goal of this observational study is to learn about the long-term outcomes of children and young people who underwent an 18-month course of oral immunotherapy (OIT) treatment for peanut, egg or milk allergy.
- Conditions
- Food Allergies, Peanut Allergies, Egg Allergy, Milk Allergy
- Trial name
- LPEM (NCT07359183)
- Where
- Australia
- Volunteers
- 147 people
- Sponsor
- Murdoch Childrens Research Institute
Egg Hypersensitivity
Safety of Nasal Influenza Immunisation in Egg Allergic Children
Egg allergy is common in early childhood, affecting at least one in 50 preschool children. Influenza ("'flu") vaccines contain egg protein, as the vaccine is cultured in hen's eggs.
- Trial name
- SNIFFLE (NCT01859039)
- Testing
- Administration of Live attenuated influenza vaccine
- Where
- 12 sites in United Kingdom
- Volunteers
- 282 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Food Allergy in Infants
Early Allergen System Experience
Multiple clinical trials have demonstrated that early allergen introduction, feeding babies common food allergens before six months, decreases children's risk of developing a food allergy.
- Trial name
- EASE (NCT06262867)
- Testing
- Ready. Set. Food! Stage 1 Mix ins
- Where
- United States
- Volunteers
- 1,110 people, healthy volunteers welcome
- Sponsor
- Prollergy dba Ready Set Food
Egg Allergy
Pancake Oral Immunotherapy For Egg Allergy In Inducing Tolerance
Oral immunotherapy (OIT) using raw/ cooked egg has good desensitisation outcomes but is associated with frequent and sometimes severe adverse events (anaphylaxis is not uncommon).
- Trial name
- POET (NCT07192510)
- Testing
- Pancake oral immunotherapy
- Where
- Singapore
- Volunteers
- 23 people
- Sponsor
- KK Women's and Children's Hospital
Hypertriglyceridemia
Metabolic Effects of Egg Protein and Unsaturated Fat Intakes in Subjects With Hypertriglyceridemia
The goal of this study is to evaluate the effects of replacing some refined starches and added sugars with a combination of egg protein and unsaturated fatty acids on markers of cardiometabolic health in men and women with…
- Trial name
- NCT02924558
- Testing
- Egg protein/unsaturated fatty acid, Control
- Volunteers
- 28 people
- Sponsor
- Midwest Center for Metabolic and Cardiovascular Research
Egg Hypersensitivity
Gradual Egg-tolerance Induction in Hen's Egg Allergic Children Who Tolerate Baked Egg (TETI-II Study)
The investigators want to test the hypothesis that a total period of 12 months of stepwise open egg introduction is not inferior when compared to a total period of 20 months gradual open egg introduction of a certain egg product…
- Trial name
- TETI-II (NCT04677790)
- Testing
- assigned period of specific dietary restrictions
- Where
- 4 sites in Belgium
- Volunteers
- 62 people
- Sponsor
- Dominque Bullens
Food Allergy in Children
Determine Immunoglobulin G4 (IgG4) Standards for Cow's Milk and Egg in Different Populations of Allergic and Non-allergic Children
The study objectives are : Determine standards of plasma levels of casein-specific immunoglobulin G4 (IgG4) and egg-specific immunoglobulin G4 (IgG4) as a function of age, in non-allergic children, in allergic children, and in…
- Trial name
- IgG4 (NCT03776474)
- Testing
- Blood collection
- Where
- France
- Volunteers
- 135 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Ig-E Mediated Food Allergy
Phase 2b Study of RPT904 as Monotherapy in Participants With IgE-Mediated Food Allergy
Phase 2b Study of RPT904 as Monotherapy in Participants With IgE-Mediated Food Allergy: This is a Phase 2b randomized, double-blind, placebo-controlled clinical trial evaluating RPT904, a next-generation anti-IgE monoclonal…
- Trial name
- NCT07220811
- Testing
- RPT904
- Where
- 37 sites in United States, Australia and 1 more
- Volunteers
- 100 people
- Sponsor
- RAPT Therapeutics, Inc., a member of the GSK plc group of companies
Food Hypersensitivity, Probiotic
Colonization and Persistence Capacity of a Multi-strain Probiotics in Pediatric Food Allergy to Milk or Egg.
This study evaluates the addition of three probiotics (Bifidobacterium longum, Bifidobacterium breve and Bifidobacterium infantis) in the treatment of pediatric food allergic children to milk or egg.
- Trial name
- NCT03639337
- Testing
- Multi-strain probiotic
- Where
- Italy
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Bambino Gesù Hospital and Research Institute
Food Allergy
Open-label Extension Study of ADP101
This is an open-label, safety extension study for participants who participated in the Harmony study (protocol ADP101-MA-01).
- Trial name
- NCT05243719
- Testing
- ADP101
- Where
- 14 sites in United States
- Volunteers
- 45 people
- Sponsor
- Alladapt Immunotherapeutics, Inc.
Egg Allergy
Oral Immunotherapy for Egg Allergy in Children Aged 6 to 16
The aim of the study is to determine the efficacy of a 12-month egg oral immunotherapy (OIT) protocol with a cooked whole egg product including yolk and egg white.
- Trial name
- NCT05740163
- Testing
- Egg product including egg white and yolk allergens
- Where
- 2 sites in Finland
- Volunteers
- 60 people
- Sponsor
- Tampere University Hospital
Egg Protein Allergy
Egg Allergy Oral Desensitization
This study evaluates whether tolerance to eggs can be induced in patients through a process of oral immunotherapy. Participants will be randomized into groups receiving oral immunotherapy and a control group that will receive no…
- Trial name
- NCT04027465
- Testing
- Egg allergy oral desensitization
- Where
- 2 sites in Canada
- Volunteers
- 50 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre