Clinical trials: Egg Hypersensitivity
Egg Hypersensitivity
Gradual Egg-tolerance Induction in Hen's Egg Allergic Children Who Tolerate Baked Egg (TETI-II Study)
The investigators want to test the hypothesis that a total period of 12 months of stepwise open egg introduction is not inferior when compared to a total period of 20 months gradual open egg introduction of a certain egg product…
- Trial name
- TETI-II (NCT04677790)
- Testing
- assigned period of specific dietary restrictions
- Where
- 4 sites in Belgium
- Volunteers
- 62 people
- Sponsor
- Dominque Bullens
Food Allergy in Infants
Oral Immunotherapy With Egg in Infants
In children allergic to egg, oral immunotherapy (OIT) with egg may accelerate that the children grow out of the food allergy. Children than have a positive oral food provocation with egg with a low threshold, will be offered to…
- Trial name
- OIT egg (NCT07540091)
- Testing
- low-dose OIT egg
- Volunteers
- 40 people
- Sponsor
- Josefine Gradman
Egg Allergy, Eligible for Vaccination Against Influenza
FluMist in Egg Allergic Patients
With the growing public health concerns of seasonal influenza and H1N1 in the United States, the primary means by which this can be addressed is with prevention, namely, vaccination against the influenza virus.
- Trial name
- FluEMIST (NCT01248208)
- Testing
- FluMist intranasal influenza vaccine, Intramuscular influenza injection ("flu shot")
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Walter Reed Army Medical Center
Ig-E Mediated Food Allergy
Phase 2b Study of RPT904 as Monotherapy in Participants With IgE-Mediated Food Allergy
Phase 2b Study of RPT904 as Monotherapy in Participants With IgE-Mediated Food Allergy: This is a Phase 2b randomized, double-blind, placebo-controlled clinical trial evaluating RPT904, a next-generation anti-IgE monoclonal…
- Trial name
- NCT07220811
- Testing
- RPT904
- Where
- 37 sites in United States, Australia and 1 more
- Volunteers
- 100 people
- Sponsor
- RAPT Therapeutics, Inc., a member of the GSK plc group of companies
Food Allergy, Egg Allergy
Efficacy and Safety of Egg Ladders in Children With IgE-Mediated Hen's Egg Protein Allergy
Hen's Egg Allergy is one of the most common food allergies in early childhood. The first-line treatment is the elimination of hen's egg proteins from the child's or maternal diet.
- Conditions
- Food Allergy, Egg Allergy, Hen Egg Allergy
- Trial name
- NCT07040111
- Testing
- oral food challenge (OFC)
- Where
- 2 sites in Poland
- Volunteers
- 94 people
- Sponsor
- Medical University of Warsaw
Eczema, Egg Allergy
Promoting Tolerance to Peanut in High-Risk Children
This study will evaluate whether early exposure to peanuts promotes tolerance and provides protection from developing peanut allergy in children who are allergic to eggs or who have severe eczema.
- Conditions
- Eczema, Egg Allergy, Food Allergy
- Trial name
- LEAP (NCT00329784)
- Testing
- Peanut Consumption Group
- Where
- United Kingdom
- Volunteers
- 640 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Food Allergy, Food Allergy in Infants
The Clinical Impact of the Basophil Activation Test to Diagnose Food Allergy
The BAT Impact study is a prospective multicentre study in the UK using a biomarker-led study design to compare the incidence of adverse events (defined as allergic reactions during oral food challenges) in a…
- Conditions
- Food Allergy, Food Allergy in Infants, Food Allergy in Children, Food Allergen Sensitisation
- Trial name
- NCT05309772
- Testing
- Basophil activation test (BAT), Oral food challenge (OFC)
- Where
- 11 sites in United Kingdom
- Volunteers
- 398 people
- Sponsor
- King's College London
Eczema, Atopic, Inflammation; Skin
Nutrients-fortified Egg Consumption on Eczema Condition in Individuals With Eczema
The study aims to assess the effects of daily consumption of nutrients-fortified eggs on eczema condition in individuals with eczema.
- Conditions
- Eczema, Atopic, Inflammation; Skin, Eczema, Hypersensitivity
- Trial name
- NCT05913791
- Testing
- Nutrients-fortified egg, Regular egg
- Where
- Singapore
- Volunteers
- 41 people
- Sponsor
- National University of Singapore
Food Allergy in Infants
Early Allergen System Experience
Multiple clinical trials have demonstrated that early allergen introduction, feeding babies common food allergens before six months, decreases children's risk of developing a food allergy.
- Trial name
- EASE (NCT06262867)
- Testing
- Ready. Set. Food! Stage 1 Mix ins
- Where
- United States
- Volunteers
- 1,110 people, healthy volunteers welcome
- Sponsor
- Prollergy dba Ready Set Food
Food Allergy
The Basophil Activation Test For Egg Allergy
In this study, basophil activation test (BAT) established by the investigators' lab was evaluated for its sensitivity and specificity in child egg allergy diagnosis.
- Trial name
- BAT (NCT06559319)
- Testing
- blood sampling
- Where
- China
- Volunteers
- 174 people
- Sponsor
- Xia Peng
Egg Hypersensitivity
Gradual Egg-tolerance Induction in Hen's Egg Allergic Children
1. The investigators here want to test the hypothesis that a total period of 18 months of gradual open introduction of a certain egg product with regard to full egg tolerance induction is not inferior when compared to a total…
- Trial name
- TETI (NCT02487420)
- Testing
- shorter or longer period of specific dietary restrictions
- Where
- 6 sites in Belgium
- Volunteers
- 86 people
- Sponsor
- Dominque Bullens
Food Allergy, Food Allergy in Infants
Basophil Activation Test to Diagnose Food Allergy
The BAT II Study is a cross-sectional diagnostic study in which children with suspected IgE-mediated allergy to foods (namely cow's milk, egg, sesame and cashew), as defined by a history of an immediate-type allergic reaction to…
- Conditions
- Food Allergy, Food Allergy in Infants, Food Allergy in Children, Food Allergen Sensitisation
- Trial name
- BAT2 (NCT03309488)
- Testing
- Oral food challenge
- Where
- United Kingdom
- Volunteers
- 600 people
- Sponsor
- King's College London
Egg Hypersensitivity
Safety of Nasal Influenza Immunisation in Egg Allergic Children
Egg allergy is common in early childhood, affecting at least one in 50 preschool children. Influenza ("'flu") vaccines contain egg protein, as the vaccine is cultured in hen's eggs.
- Trial name
- SNIFFLE (NCT01859039)
- Testing
- Administration of Live attenuated influenza vaccine
- Where
- 12 sites in United Kingdom
- Volunteers
- 282 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Allergy
Follow up of Patients After Oral Immunotherapy for Cow's Milk, Eggs and Peanuts
Food allergy is a potentially life threatening condition. The current practice consists of elimination diet and injectable epinephrine in case of a reaction.
- Trial name
- OIT followup (NCT01999387)
- Testing
- Allergenic food
- Where
- Israel
- Volunteers
- 500 people
- Sponsor
- Assaf-Harofeh Medical Center
Food Allergy
The Effect of Per Oral Immunotherapy in Severe Milk, Peanut and Egg Allergy in Adults
The aim is to analyse the results of per oral immunotherapy treatment in severe milk, peanut or egg allergy in adults. This is the second part of the oral immunotherapy study in adults at Skin and Allergy Hospital.
- Trial name
- NCT03361072
- Testing
- Oral immunotherapy
- Where
- Finland
- Volunteers
- 30 people
- Sponsor
- Helsinki University Central Hospital
Peanut Allergy, Milk Allergy, Cow's
Investigating Modified Protocols of Oral Immunotherapy to Validate Efficacy and Safety
Protocols for Oral Immunotherapy (OIT) for the main food allergens have been recently incorporated in clinical practice for food allergies and their clinical benefits have been acknowledged in European and Canadian official…
- Conditions
- Peanut Allergy, Milk Allergy, Cow's, Egg Allergy
- Trial name
- IMPROVES (NCT06256146)
- Testing
- Food allergy desensitization / Oral Immunotherapy
- Where
- Canada
- Volunteers
- 360 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Food Allergy
The Effect of Per Oral Immunotherapy in Severe IgE Mediated Egg, Milk, and Nut Allergy in Adults
In Finland, the estimated prevalence of physician-diagnosed food allergy in 1-4 year old children is 9%, and the most common allergen is milk. The overall food allergy has been reported to be 3.7%.
- Trial name
- NCT01822353
- Testing
- Dietary supplement
- Where
- Finland
- Volunteers
- 23 people
- Sponsor
- Helsinki University Central Hospital
PreDiabetes
Effect of Egg Consumption on Cardiometabolic Health in Prediabetic Subjects.
The objective of this trial is to assess the effects of whole egg consumption (12 per week), compared to energy-matched typical breakfast control foods, on insulin sensitivity and other markers of metabolic health, including…
- Trial name
- NCT03332927
- Testing
- Egg based breakfast foods, Non-egg based breakfast foods
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Midwest Center for Metabolic and Cardiovascular Research
Food Allergy in Children, Milk Allergy
Comparison Between a Rush and a Conventional Oral Immunotherapy Protocol to Treat Cow's Milk and Hen´s Egg Allergy. CompITO Study
This study investigates the efficacy and safety of two different OIT schemes to treat milk and egg allergic children
- Conditions
- Food Allergy in Children, Milk Allergy, Egg Allergy
- Trial name
- compITO (NCT06976775)
- Testing
- "Rush" regimen, "Conventional" regimen
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Pablo Rodríguez del Rio
Food Allergies, Peanut Allergies
A Long Term, Observational Follow-Up Study of Children and Young People Who Underwent an 18-Month Course of Oral Immunotherapy Treatment for Peanut, Egg or Milk Allergy (5-15 Years Post-Treatment)
The goal of this observational study is to learn about the long-term outcomes of children and young people who underwent an 18-month course of oral immunotherapy (OIT) treatment for peanut, egg or milk allergy.
- Conditions
- Food Allergies, Peanut Allergies, Egg Allergy, Milk Allergy
- Trial name
- LPEM (NCT07359183)
- Where
- Australia
- Volunteers
- 147 people
- Sponsor
- Murdoch Childrens Research Institute