Clinical trials: Elastography, open to volunteers
COPD, Healthy Adult
Shear Wave Elastography of Intercostal Muscles for the Non-invasive Assessment of the Work of BreathinG
Quantifying respiratory effort is a key step in physiological and clinical research on exercise tolerance, mechanisms of fatigability, and ventilatory impairment.
- Trial name
- SWING (NCT07371754)
- Testing
- Intercostal muscle shear wave elastography (SWE) during standardized inspiratory loading
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Groupe Hospitalier du Havre
Dysphagia After Stroke, Stroke
Effect of Visual Biofeedback-Assisted Oropharyngeal Exercises in Post-Stroke Dysphagia
Post-stroke dysphagia is a common complication that negatively affects nutritional status, quality of life, and morbidity. Conventional swallowing rehabilitation, including oropharyngeal exercises and neuromuscular electrical…
- Conditions
- Dysphagia After Stroke, Stroke, Dysphagia, Swallowing Disorders
- Trial name
- NCT07492719
- Testing
- Suprahyoid Neuromuscular Electrical Stimulation (NMES), Visual Biofeedback Training, Conventional Oropharyngeal Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Gazi University
Ulcerative Colitis
Development of Novel Imaging and Molecular Biomarkers of Fibrosis in Patient With Ulcerative Colitis
Prospective multicenter interventional non-randomized cross-sectional study. Ultrasound operators will be blinded to clinical and endoscopic findings and the endoscopist will be blinded of the clinical and ultrasound findings.
- Trial name
- NCT06516237
- Testing
- to determine molecular and epigenetic biomarkers
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- IRCCS San Raffaele
Portal Hypertension, Spleen Disease
Liver Cirrhosis Complicated by Clinically Significant Portal Hypertension
Portal hypertension is a major complication of cirrhosis. HVPG is the diagnostic gold standard but is invasive. Non-invasive tools such as spleen stiffness measurement (SSM) and CEUS show promise for assessing CSPH, though they…
- Conditions
- Portal Hypertension, Spleen Disease, Cirrhosis
- Trial name
- CIRCE (NCT07365709)
- Testing
- SonoVue
- Volunteers
- 107 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Polyneuropathies
Ultrasonography in Diagnosis of Polyneuropathy
The main goal of this trial is to establish recommendations for clinical practice that enhance the reliability, accessibility and convenience of sheer wave elastography as a routine diagnostic test for diverse peripheral…
- Trial name
- NCT06390527
- Volunteers
- 120 people
- Sponsor
- University Medical Centre Ljubljana
Chronic Hepatitis B, Liver Fibrosis
MR Elastography for Assessing Liver Fibrosis in Chronic Hepatitis B
How to construct a non-invasive, accurate, and convenient method to evaluate the severity of liver fibrosis (LF) is an important general problem in the management of patients with chronic hepatitis B (CHB).
- Trial name
- NCT06779058
- Testing
- MRE, Liver biopsy
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Shengjing Hospital
Congenital Diaphragmatic Hernia
Preliminary Study of Pediatric Diaphragmatic Elastography
This diaphragmatic elastography study is a preliminary pilot study to have first values of diaphragmatic stiffness in patients with a history of diaphragmatic hernia and to estimate the difference in stiffness compared to a group…
- Trial name
- ECHODIA (NCT06666140)
- Testing
- Ultrasonic elastography
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Strasbourg, France
Psoriatic Arthritis, Enthesitis
Ultrasound and Shear Wave Elastography Assessment of Entheses in Psoriatic Arthritis
Psoriatic arthritis (PsA) is a chronic inflammatory disease that frequently involves the entheses, where tendons, ligaments, and fascia insert into bone.
- Trial name
- SWE-PsA (NCT07785089)
- Testing
- Grayscale Ultrasonography, Power Doppler Ultrasonography, and Shear Wave Elastography
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Marmara University
Metabolic Dysfunction-Associated Steatotic Liver Disease, Pediatric Obesity
Non-Invasive Diagnostic Panel for MASLD in Children With Obesity
This prospective, single-center, two-group observational study evaluates a non-invasive multi-parameter diagnostic panel for metabolic dysfunction-associated steatotic liver disease (MASLD) in children with obesity.
- Conditions
- Metabolic Dysfunction-Associated Steatotic Liver Disease, Pediatric Obesity, Insulin Resistance Syndrome
- Trial name
- PedMASLD-Pilot (NCT07731360)
- Testing
- Non-Invasive Multi-Parameter Diagnostic Panel
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Kayseri City Hospital
Colorectal Cancer, Coffee
COffee and Metabolites Modulating the Gut MicrobiomE in Colorectal caNCER
This is research study is assessing the effects of 6-g daily use of freeze-dried instant coffee on liver fat and fibrosis and the gut microbiome and metabolome in patients who have completed routine treatment (including surgery…
- Conditions
- Colorectal Cancer, Coffee, Gastrointestinal Microbiome, Stenosis
- Trial name
- COMMENCER (NCT05692024)
- Testing
- Nestlé NESCAFÉ® TASTER'S CHOICE® House Blend capsule.
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Massachusetts General Hospital
Metabolic Syndrome, Obesity
A Clinical Study on Using Multimodal Ultrasound to Assess Muscle Mass in Metabolic Diseases
This study aims to evaluate the clinical value of multimodal ultrasound for assessing muscle mass in patients with metabolic diseases, including metabolic syndrome, type 2 diabetes, and simple obesity.
- Conditions
- Metabolic Syndrome, Obesity, Sarcopenia, Type 2 Diabetes
- Trial name
- NCT07836088
- Where
- China
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Zhangzhou Municipal Hospital
Supraspinatus Injury
Added Value of Sonoelastography in Assessment of Traumatic and Non Traumatic Supraspinatus Tendinopathy and Tear Compared with Magnetic Resonance Imaging
Primary Aims: To assess the value of sonoelastography in the evaluation of supraspinatus tendon abnormalities. Secondary Aims: 1.
- Trial name
- NCT06803303
- Testing
- sonoelastography
- Volunteers
- 43 people
- Sponsor
- Assiut University
HCC - Hepatocellular Carcinoma
Can Hepatic-splenic Elastography Predict the Risk of Hepatocellular Recurrence After Radiofrequency Ablation?
The study aims to assess whether there is an association between hepatic and splenic elastography values and the risk of HCC recurrence after treatment with RFA
- Trial name
- ELASTORFA (NCT06777017)
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Amyloidosis
A Study Of Myocardial Stiffness In Amyloidosis With Magnetic Resonance Elastography
This is a prospective case control study to determine the feasibility and utility of myocardial stiffness assessment by cardiac magnetic resonance elastography (MRE) in patients with cardiac amyloidosis.
- Trial name
- NCT07216469
- Testing
- Magnetic Resonance Elastography (MRE)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Diaphragm Ultrasound, Diaphragm Dysfunction
Correlation of Diaphragm Shear-Wave Elastography With Transdiaphragmatic Pressure in Healthy Adults: a Feasibility Study
Changes in intrapleural pressure after lung volume reduction in Chronic Obstructive Pulmonary disease (COPD) patients can lead to complications, including an increased risk of pneumothorax.
- Conditions
- Diaphragm Ultrasound, Diaphragm Dysfunction, Health Adult Subjects
- Trial name
- PLEASSURE 1 (NCT07253480)
- Testing
- shear wave elastography of the diaphragm
- Where
- Netherlands
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Isala
Pancreatic Masses
Mri and Ultrasound Elastography in Pancreatic Masses
To compare transcutaneous ultrasound elstography to Diffusion weighted MRI in differentiating between benign and malignant pancreatic masses.
- Trial name
- NCT06895655
- Testing
- MRI and Ultrasound Elastography
- Volunteers
- 50 people
- Sponsor
- Assiut University
Arterial Hypertension, Chronic Kidney Disease, Primary Aldosteronism
Kidney Stiffness Measured by Ultrasound in Patients With High Blood Pressure and Healthy Volunteers
High blood pressure (hypertension) is a leading cause of kidney damage, but detecting early kidney changes remains challenging with currently available tools.
- Conditions
- Arterial Hypertension, Chronic Kidney Disease, Primary Aldosteronism, Arterial Stenosis
- Trial name
- K-STRESS (NCT07914075)
- Where
- Italy
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera di Padova
Patellar Tendinopathy / Jumpers Knee
Comparison of Ultrasound-guided Electrolysis Therapy vs. Sham Electrolysis in Patients With Patellar Tendinopathy: A Prospective Randomized Study Including MRI and Shear-wave Ultrasound Elastography Imaging
Study Background and Purpose Tendinopathies are common and debilitating musculoskeletal disorders that often lead to chronic pain and reduced mobility.
- Trial name
- NCT06939491
- Testing
- Ultrasound guided electrolysis therapy
- Where
- Germany
- Volunteers
- 74 people
- Sponsor
- Gymna Uniphy
Chronic Viral Hepatitis
Agreement and Reliability of Transient Elastography
The aim of this study is to assess agreement, smallest detectable change, and reliability of repeated measurements of liver stiffness of transient elastography in patients with chronic viral hepatitis, and to explore factors…
- Trial name
- HEPSCAN (NCT05686785)
- Testing
- Transient elastography
- Where
- Sweden
- Volunteers
- 300 people
- Sponsor
- Lund University
Pleural Diseases
The Efficacy of Shear-wave Elastography-guided Biopsy for Diagnosis in Pleural Disease
To investigate the information from shear-wave elastography on pleural tissues will improve the diagnosis of pleural diseases, as to increase the diagnostic yield in ultrasound-guided transthoracic pleura biopsy.
- Trial name
- NCT06226909
- Testing
- different types of ultrasound technique
- Where
- Taiwan
- Volunteers
- 234 people
- Sponsor
- National Taiwan University Hospital