Clinical trials: Elder
Obstructive Sleep Apnea of Adult
Effect of Continuous Positive Airway Pressure on Chronotype, Dietary Intake, and Cardiovascular Risk Markers
In this study the investigators will evaluate chronotype, food intake pattern, and cardiovascular risk markers of elder individuals with OSA, in use of CPAP, when submitted to two weeks of CPAP withdrawal.
- Trial name
- NCT04262960
- Testing
- Device: active CPAP
- Where
- Brazil
- Volunteers
- 44 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Vitamin D Deficiency, Accidental Falls
Improving Vitamin D Status in Home-bound Elders
In the past two decades, the role of vitamin D has extended beyond bone health to encompass a wide range of biological activities important to physical function in older adults.
- Trial name
- MOW VitD (NCT01410084)
- Testing
- Vitamin D3, Vitamin E
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Wake Forest University Health Sciences
Pneumococcal Infections
Immunogenicity and Reactogenicity of Pneumococcal Polysaccharide and Conjugate Vaccines in Native Elders
To test the hypothesis that immune responses to 23-valent pneumococcal polysaccharide vaccine (PPV-23) could be improved in Alaska Native elders by immune priming with 7-valent pneumococcal conjugate vaccine (PCV-7), we assessed…
- Trial name
- NCT00153543
- Testing
- PCV7 + PPV23, 2 months, PCV7 + PPV23, 6 months
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Chronic Low Back Pain
Expressive Art Therapy for Elder Adults With Chronic Low Back Pain
This research project aims to assess the feasibility of expressive art therapy for elderly adults with chronic low back pain and to evaluate the preliminary efficacy of combining art therapy with exercise intervention.
- Trial name
- NCT07141082
- Testing
- Art therapy combined with Exercise, Exercise
- Where
- Hong Kong
- Volunteers
- 30 people
- Sponsor
- The Hong Kong Polytechnic University
Aging, Alzheimer's Disease
Effects of Exercise and Cognitive Training on Cognitive Function in Older Adults
The purpose of this study is to gain a better understanding of the effects of exercise and cognitive training on improving brain function in healthy older adults who may be at risk for developing Alzheimer's Disease.
- Trial name
- NCT01038726
- Testing
- Exercise Training, Cognitive Training, Flexibility Training
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Frailty
Effect of an Oral Frailty Measures Intervention Programs in Institutionalized Elders
This is a compelling 16-week prospective, double-blind, whole-cluster randomized controlled trial(RCT).This study will recruit 226 older adults over the age of 65.Based on King's goal attainment theory, a program to promote oral…
- Trial name
- NCT06536985
- Testing
- treatment group, Contral group
- Where
- China
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- Hangzhou Normal University
Mild Cognitive Impairment
Lithium As a Treatment to Prevent Impairment of Cognition in Elders
Alzheimer's disease (AD) is the most common cause of dementia in adults 65 years and older. AD leads to a complete loss of memory and independent function, and presently there is no cure.
- Trial name
- LATTICE (NCT03185208)
- Testing
- Lithium Carbonate
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- Ariel Gildengers, MD
Muscular Atrophy, Sensitivity Training Groups
Effects of Inspiratory Muscle Training in Elders
Aging causes anatomical and physiological changes in the respiratory system and respiratory muscle strength with decline in its maximum function.
- Conditions
- Muscular Atrophy, Sensitivity Training Groups, Aging
- Trial name
- NCT01791010
- Testing
- Inspiratory muscle training
- Where
- Brazil
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Hypertension
Hypertension Approaches in the Elderly: a Lifestyle Study
Two-center randomized, parallel, controlled trial which will compare a pragmatic combined training program with a health education program in 184 older adults with hypertension.
- Trial name
- HAEL (NCT03264443)
- Testing
- Health education, Combined training
- Where
- 2 sites in Brazil
- Volunteers
- 184 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Healthy Elder People
Feru-guard and General Antioxidant Capacity in Older People
To determine if Feru-guard, a dietary supplement, can decrease general oxidation and inflammation in people who are ages 65-89 years old. Also to determine if Feru-guard is safe in older people when given for 3 months.
- Trial name
- NCT07801521
- Testing
- Feru-guard
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Oregon Health and Science University
Dementia, Caregivers
The Balance Study Balancing Life and Reducing Stress For Those Providing Elder Care
The primary goals of this exploratory/developmental (R21) study are to evaluate the feasibility and acceptability of a MBSR intervention for caregivers of patients with dementia, and to estimate the effectiveness of program…
- Conditions
- Dementia, Caregivers, Stress
- Trial name
- Balance (NCT00615082)
- Testing
- Mindfulness-Based Stress Reduction, Caregiver Education & Social Support
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- HealthPartners Institute
Non-Small Cell Lung Cancer
Gemcitabine and Carboplatin for Elderly Patient With Lung Cancer
A comparison of biweekly combination chemotherapy (gemcitabine plus carboplatin) with weekly gemcitabine in elder patients (> 75) with previously untreated advanced non-small cell lung cancer.
- Trial name
- GEEP (NCT00881296)
- Testing
- gemcitabine and carboplatin, Gemcitabine
- Where
- Japan
- Volunteers
- 60 people
- Sponsor
- Hamamatsu University
Frail Elderly Syndrome
GrandMove Project to Promote Elders' Robustness Against Frailty
This is a single-blind, cluster randomized, cross-over trial to investigate the effectiveness of (1) a 6-month aerobic exercise program, (2) a 6-month resistance exercise program, versus (3) a 6-month psychoeducation program on…
- Trial name
- GrandMove (NCT05397288)
- Testing
- Resistance exercise (R), Aerobic exercise (A), Healthy lifestyle education (E)
- Where
- Hong Kong
- Volunteers
- 390 people
- Sponsor
- The University of Hong Kong
Postoperative Delirium in Elder Patients After Spine Surgery
Predictors of Postoperative Delirium in Elder Patients After Spine Surgery: Regional Cerebral Oxygen Saturation
Postoperative delirium is an important problem in patients undergoing major surgery. The incidence of delirium was 12.5% in the patients over 70 years old undergoing spine surgery.
- Trial name
- NCT02331953
- Where
- South Korea
- Volunteers
- 109 people
- Sponsor
- Yonsei University
Elder Abuse
A Path to Prevention of Elder Abuse in Long-term Care. General Population Prevalence Study
The goal of this cross-sectional study is to learn about how common experiences of different forms of abuse are among people over the age of 65 years in Sweden.
- Trial name
- APPEAL (NCT06786065)
- Testing
- No intervention (observational study)
- Where
- Sweden
- Volunteers
- 7,727 people, healthy volunteers welcome
- Sponsor
- Linkoeping University
Elderly
Eldercare Technology in a Silver Culture Village
The aim of this project is to create ten smart devices that involve combining an interactive art environment with IC technology, arts and health administration.
- Trial name
- NCT03084107
- Testing
- Questionnaire
- Where
- Taiwan
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Sarcopenia in Elderly, Tai Chi
The Effect of Tai Chi Exercise Among Elders With Sarcopenia
Sarcopenia has been defined as a disease which presented as low muscles strength, low muscle quantity or quality and low physical activity.
- Trial name
- NCT05145036
- Testing
- Tai-Chi, Comprehensive training
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Aging, Cognitive Decline
ACHIEVE Brain Health Follow-Up Study
The ACHIEVE Brain Health Follow-Up Study is a 3-year follow-up to the Aging and Cognitive Health Evaluation in Elders (ACHIEVE) randomized study to determine the long-term effect of hearing intervention vs.
- Conditions
- Aging, Cognitive Decline, Mild Cognitive Impairment, Dementia
- Trial name
- ACHIEVE-BHFU (NCT05532657)
- Testing
- Hearing intervention, Successful aging/delayed hearing intervention
- Where
- 4 sites in United States
- Volunteers
- 629 people
- Sponsor
- Johns Hopkins University
Sarcopenia, Falls Patient
Sarcopenia and Risk of Fall in Osteoporotic Postmenopausal Women
The main scope of the present pilot study is to evaluate the possible association between the status of sarcopenia and the risk of fall in osteoporotic postmenopausal women.
- Conditions
- Sarcopenia, Falls Patient, Osteoporosis, Postmenopausal
- Trial name
- Sarcopenia (NCT03382366)
- Testing
- Blood sampling, risk of fall evaluation, and MR acquisition.
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Dialectical Behaviour Therapy
Pathways to Care-Understanding the Impact of an Indigenous Elder Co-lead in Perinatal Dialectical Behaviour Therapy
To integrate traditional Indigenous Knowledge with gold-standard therapy to enrich the patient experience from an anti-oppressive, culturally safe perspective for marginalized individuals with psychosocially complex pregnancies.
- Trial name
- NCT06466694
- Testing
- Modified Dialectical Behavioural Therapy
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Manitoba