Clinical trials: Elderly Adults
Healthy Participants, Young Healthy Adults
CanCan Body Composition Study
The aim of this study is to develop a dataset with reference body composition measurements using criterion methods. This dataset will be used to develop new protocols to study patients with cancer.
- Conditions
- Healthy Participants, Young Healthy Adults, Elderly (People Aged 65 or More)
- Trial name
- Cancan (NCT07305753)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Retirement, Healthy Adults
Transitions and Old Age Potential - 1st, 2nd, and 3rd Wave
With the third wave of the Transitions and Old Age Potential (TOP) study, the longitudinal study of initially 5,002 individuals was completed in 2019.
- Conditions
- Retirement, Healthy Adults, Elderly
- Trial name
- TOP (NCT07301112)
- Volunteers
- 5,002 people, healthy volunteers welcome
- Sponsor
- Jacobs University Bremen gGmbH
Community Dwelling, Elderly Adults
Effectiveness of Active Brain Construction Program in Community-Dwelling Older Adults
The urgency of health promotion and dementia prevention is paramount. In 2019, the World Health Organization announced the "Risk reduction of cognitive decline and dementia," which reviewed evidence-based prevention aspects and…
- Conditions
- Community Dwelling, Elderly Adults, Lifestyle Risk Reduction
- Trial name
- NCT07282626
- Testing
- ABC program with coaching, Active comparator (ABC Program)
- Where
- Taiwan
- Volunteers
- 75 people
- Sponsor
- National Taiwan University Hospital
Elderly, Older Adults, Aging Brain
Effects of Physical Exercise and Cognitive Training on Quality of Life in Older Women
Ageing exposes people to a progressive loss of cognitive and functional abilities, especially in women. The aim of the study is to investigate the effectiveness of different types of intervention, based on physical exercise…
- Trial name
- INCOGNITO (NCT07244562)
- Testing
- EXERCISE TRAINING WITH OR WITHOUT MEDICATION, Exercise plus cognitive training, Exercise plus cognitive stimulus at home
- Where
- Italy
- Volunteers
- 124 people
- Sponsor
- University Hospital of Ferrara
Obesity (Disorder), Obesity
Effect of Vitamin D on Body Composition and Functionality of Older Adults
Older adults with obesity often experience a gradual loss of muscle mass and muscle strength, a condition sometimes described as sarcopenic obesity.
- Conditions
- Obesity (Disorder), Obesity, Sarcopenia, Sarcopenia in Elderly
- Trial name
- NCT07275177
- Testing
- Vitamin D
- Where
- Mexico
- Volunteers
- 29 people
- Sponsor
- Universidad Autónoma Benito Juárez de Oaxaca
Frailty at Older Adults, Post-Traumatic Stress Disorder in Old Age
Multimodal Intervention for Older Adults After an Earthquake
This randomized controlled study was conducted among older adults (≥65 years) living in temporary container housing in Kahramanmaraş after the February 2023 earthquakes.
- Conditions
- Frailty at Older Adults, Post-Traumatic Stress Disorder in Old Age, Depression in Adults, Malnutrition Elderly
- Trial name
- NCT07273253
- Testing
- Multimodal intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Constipation in Older Adults, Functional Constipation in Elderly
The Effects of Prune Juice on Bowel Movement Patterns, Constipation Symptoms, and Quality of Life
This study investigates the effects of different prune juice dosages on bowel movement patterns, constipation symptoms, and quality of life in older adults.
- Trial name
- NCT06963125
- Testing
- Low-Dose Prune Juice, Medium-Dose Prune Juice, High-Dose Prune Juice
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Dalin Tzu Chi General Hospital
Fractures, Hip, Femoral Neck Fractures
Preoperative Use of Peripheral Nerve Blocks in Elderly Patients With Hip Fractures
The goal of this clinical trial is to explore the effects of different peripheral nerve blocks in older adults with hip fractures. It will also explore the safety of preoperative administration of peripheral nerve blocks.
- Conditions
- Fractures, Hip, Femoral Neck Fractures, Intertrochanteric Fractures, Subtrochanteric Fractures
- Trial name
- NCT07130006
- Testing
- PENG and LFCN peripheral nerve blocks with spinal anesthesia, FN and LFCN peripheral nerve blocks with spinal anesthesia, FIC peripheral nerve block with spinal anesthesia
- Where
- Croatia
- Volunteers
- 256 people
- Sponsor
- University Hospital of Split
Sarcopenia in Elderly, Institutionalized Older Adults
Observational and Analytical Study on the Diagnostic Criteria for Sarcopenia in Institutionalized Older Adults and Those Living in the Community
Sarcopenia is one of the main problems in the elderly population. However, its diagnostic criteria have not yet been studied in two specific populations, namely institutionalized older adults in nursing homes vs…
- Conditions
- Sarcopenia in Elderly, Institutionalized Older Adults, Community-dwelling Elderly
- Trial name
- NCT07080554
- Where
- Spain
- Volunteers
- 415 people, healthy volunteers welcome
- Sponsor
- University of Extremadura
Frailty in Adult Surgery, Frail Elderly Syndrome
Patient's Database: Prepare for Your Surgery Program
Frailty is a multidimensional syndrome that predominantly affects older people and people with long-term treatments such as cancer and chronic pain.
- Conditions
- Frailty in Adult Surgery, Frail Elderly Syndrome, Database, Perioperative Care
- Trial name
- NCT06857981
- Testing
- Clinical data collection
- Where
- 2 sites in Chile
- Volunteers
- 120 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Alzheimer's Disease, Healthy Non-elderly and Elderly Adults
Multiple Ascending Dose Safety, Tolerability, PK Study of AL001 in Alzheimer's Disease Patients & Healthy Adult Subjects
This is a Phase 1/2a, multi-center, placebo-controlled, double-blinded, randomized, multiple ascending dose (MAD) clinical trial to determine the safety and maximum tolerated dose of AL001.
- Trial name
- "MAD" (NCT05363293)
- Testing
- AL001
- Where
- 2 sites in United States, Canada
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Alzamend Neuro, Inc.
Eccentric Exercise, Home-based Training
Effects of Eccentric Training at Long Muscle Length on Functional Capacities of Elderly Adults
As aging leads to a decline in muscle function and overall physical performance, interventions targeting muscle strength and neuromechanical properties are critical for maintaining functional independence in older adults.
- Conditions
- Eccentric Exercise, Home-based Training, Elderly Adults
- Trial name
- EMULE (NCT06953258)
- Testing
- Home-based eccentric training at long muscle length, Conventional home-based training
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Robin Souron
Sarcopenia in Elderly, Frailty
Safety and Efficacy of Isomyosamine in Reducing Inflammation and Treating Muscle Loss in Older Adults After Hip or Thigh Bone Fractures
This Phase II clinical study investigates the safety and effectiveness of a new drug, Isomyosamine, in patients with sarcopenia or frailty, conditions associated with aging and muscle weakness.
- Conditions
- Sarcopenia in Elderly, Frailty, Frailty/Sarcopenia, Frailty in Older Adults
- Trial name
- NCT06942182
- Testing
- Isomyosamine 250mg
- Volunteers
- 60 people
- Sponsor
- TNF Pharmaceuticals, Inc.
Colorectal Cancer, Oncologic Complications
The SaVe Project-Sarcopenia and Vertigo in Aging Patients With Colorectal Cancer
The goal of this clinical trial is to learn about the cause of dizziness and decline in walking ability in in older adults ≥65 years during chemotherapy treatment for colorectal cancer.
- Conditions
- Colorectal Cancer, Oncologic Complications, Comprehensive Geriatric Assessment, Vestibular Rehabilitation
- Trial name
- SaVe (NCT05710809)
- Testing
- Targeted specialized physical group-based exercise and Comprehensive Geriatric Assessement
- Where
- 2 sites in Denmark
- Volunteers
- 150 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Frail Elderly Syndrome, Older Adults
A Digital Home-Based Physiotherapy Program for Active Aging
This clinical trial will aim to understand the effects of the TRAK-SILVER digital platform on pre-frail and older adults living at home, assessing its impact on physical activity level, emotional variables, and overall quality of…
- Trial name
- TRAK-SILVER (NCT06381336)
- Testing
- TRAK-SILVER platform
- Where
- Spain
- Volunteers
- 72 people
- Sponsor
- Trak Health Solutions S.L.
Sarcopenia in Elderly, Cachexia; Cancer; Sarcopenia
Body Composition in Older Adults
The primary aim of the study is to explore body composition in older adults (aged 70 years and over) with cancer, undergoing systemic anticancer treatment.
- Conditions
- Sarcopenia in Elderly, Cachexia; Cancer; Sarcopenia, Body Composition Changes, Older Adults
- Trial name
- BODI (NCT06630754)
- Testing
- No Intervention: Observational Cohort
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Surgery, Old Age; Debility
Pre-surgical Protocol for Frail Elderly People in Order to Reduce Hospitalization Days (APOPM).
Elderly people (EP) have increased, as well as life expectancy at birth. In Chile there are more than 2 million 800 thousand EP, which corresponds to 1/6 of the Chilean population.
- Conditions
- Surgery, Old Age; Debility, Frail Elderly Syndrome, Post-Operative Confusion
- Trial name
- APOPM (NCT04770259)
- Testing
- Timely pre-surgical conditioning
- Where
- 2 sites in Chile
- Volunteers
- 87 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Older Adults, Gastro-Intestinal Cancer
PeRsonalizing the Approach to the Oncologic Frail Individual Through Tailored Assessment and Intervention (PROFIT Study)
The PROFIT study has two complementary aims. The first aim is to compare, in a cohort study enrolling N=257 older adults (>65 years) with lung, gastrointestinal and prostate cancer, different easy measures of frailty (Geriatric 8…
- Conditions
- Older Adults, Gastro-Intestinal Cancer, Prostate Cancer, Lung Cancer
- Trial name
- PROFIT (NCT05319145)
- Testing
- Intervention group, Control group
- Where
- 3 sites in Andorra, Spain
- Volunteers
- 268 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Elderly Study Participants, Adult Study Participants
A Study to Test the Safety and Tolerability of Single and Multiple Doses of Padsevonil in Adult and Elderly Study Participants
The purpose of the study is to evaluate the plasma pharmacokinetic of padsevonil in adult and elderly study participants.
- Trial name
- NCT04013191
- Testing
- Padsevonil
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- UCB Biopharma S.P.R.L.
Healthy Adult Subjects, Healthy Elderly Subjects
Multiple Dose Study Of BIIB118 (PF-05251749) In Healthy Volunteers
This is the first clinical trial to evaluate ascending multiple oral doses in healthy adult and healthy elderly subjects to characterize the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of BIIB118
- Trial name
- NCT02691702
- Testing
- BIIB118, Melatonin
- Where
- 2 sites in United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Biogen