Clinical trials: Elderly People
HIV/AIDS, Chronic Pain
Acceptance and Commitment Therapy for Aging People Living With HIV in Chronic Pain
Chronic pain impacts a large proportion of aging people living with HIV (aPLWH) and involves factors directly related to HIV (neurotoxicity) and psychosocial co-morbidities common in aPLWH (i.e. social isolation and loneliness).
- Trial name
- NCT03699020
- Testing
- Acceptance and Commitment Therapy (ACT), Chronic Pain Education
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Elderly Patients With a Solid Tumor
Are the Fried Criteria Predictive of a Functional Decline in Older People With Solid Malignant Tumors?
Identifying the frail elderly patients or those at risk of becoming frail has become a cornerstone of modern geriatric medicine. Many instruments have been developed to identify fragility at the individual level.
- Trial name
- NCT02662179
- Testing
- Quality of life evaluation, Functional decline assessment, Physical decline assessment
- Where
- 2 sites in Belgium
- Volunteers
- 62 people
- Sponsor
- Brugmann University Hospital
Idiopathic Normal Pressure Hydrocephalus (INPH), Gait Disorders, Neurologic
Unsteady Gait in Older People May be a Common and Treatable Neurological Disease Associated With Increased Mortality
We live in an aging population and a third of the older population has a gait disorder that may cause institutionalization, and increased mortality.
- Conditions
- Idiopathic Normal Pressure Hydrocephalus (INPH), Gait Disorders, Neurologic, Gait Disorders in Old Age
- Trial name
- VESPR2 (NCT07137403)
- Where
- Sweden
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Umeå University
Frailty, Comprehensive Geriatric Assessment
Integrated Care with GP Participation for Older Persons in the Ambulatory Care Hub: a Prospective Cohort Study.
Comprehensive Geriatric Assessment (CGA) demonstrates positive outcomes amoung community-dwelling older people living with frailty.
- Trial name
- NCT05527223
- Where
- Ireland
- Volunteers
- 303 people
- Sponsor
- University of Limerick
Surgery, Old Age; Debility
Pre-surgical Protocol for Frail Elderly People in Order to Reduce Hospitalization Days (APOPM).
Elderly people (EP) have increased, as well as life expectancy at birth. In Chile there are more than 2 million 800 thousand EP, which corresponds to 1/6 of the Chilean population.
- Conditions
- Surgery, Old Age; Debility, Frail Elderly Syndrome, Post-Operative Confusion
- Trial name
- APOPM (NCT04770259)
- Testing
- Timely pre-surgical conditioning
- Where
- 2 sites in Chile
- Volunteers
- 87 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Elderly Persons
Biological MArkers of FRAilty in Elderly Subjects
Epidemiological data from Europe have shown that around 30% of subjects aged over 65 years of age are pre-frail, and 15% are frail.
- Trial name
- MAFRA (NCT02816580)
- Testing
- Blood collection
- Where
- France
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Older People, Sleep Problems
A Warm Foot Bath, Sleep Quality and Comfort Level
Objectives: To determine the effectiveness of a warm foot bath on sleep quality and comfort level among elderly individuals with sleep problems. Design and methods: This study was a randomized controlled trial.
- Trial name
- NCT04413188
- Testing
- Warm foot bath
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ordu University
Eldery People, Sedentarity
Impact of Plant Proteins and Exercise on Protein Metabolism in Older Adults
To gain mechanistic insights by examining the impact of innovative plant-protein fibre products, physical activity interventions on digestibility, amino acid bioavailability and whole-body protein metabolism in older persons
- Trial name
- APPETITE (NCT07155824)
- Testing
- Whey and plant protein blend
- Where
- France
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Accidental Falls
The HIP-HOP Flooring Study: Helping Injury Prevention in Hospitalised Older People
In hospitals, older people can fall and hurt themselves. The investigators want to see if a new type of flooring can help stop people hurting themselves as badly, if they accidentally fall.
- Trial name
- NCT00817869
- Testing
- New flooring
- Where
- 8 sites in United Kingdom
- Volunteers
- 571 people
- Sponsor
- University of Portsmouth
Mortality
Statins In The Elderly
In patients ≥ 75 years, there is no evidence that statins in primary prevention are associated with a decreased mortality and recent US recommendations consider statins in people only between 40 and 75 years.
- Trial name
- SITE (NCT02547883)
- Testing
- Cessation of statin
- Where
- France
- Volunteers
- 1,230 people
- Sponsor
- University Hospital, Bordeaux
COVID-19
A Study to Learn About the Study Medicines (Nirmatrelvir Plus Ritonavir) in People Aged 12 Years or Older With COVID-19 and a Compromised Immune System
The purpose of this clinical trial is to learn about the safety and effects of the study medicine (called Nirmatrelvir/Ritonavir) for the possible treatment of COVID-19.
- Trial name
- NCT05438602
- Testing
- Nirmatrelvir, Ritonavir
- Where
- 84 sites in United States, Australia and 7 more
- Volunteers
- 158 people
- Sponsor
- Pfizer
Old Age
Relationships Between Sexuality and Mental Health in Older People
The prevalence of sexual activity decreases with age, particularly among individuals over 60 years old. Although physical dysfunctions, such as erectile disorders, play a role, the decline in sexuality is also linked to cultural…
- Trial name
- PASS (NCT07252583)
- Testing
- questionnaires of quality of life
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Clermont-Ferrand
Dementia, Neurocognitive Disorders
Effectiveness and Cost-Effectiveness of Cognitive Stimulation Therapy - Spain (CST-ES) in People Living With Dementia
This study aims to evaluate the effectiveness and cost-effectiveness of CST-ES, the Spanish adaptation of Cognitive Stimulation Therapy (CST), to improve cognition and quality of life in people with mild to moderate dementia.
- Conditions
- Dementia, Neurocognitive Disorders, Mild Cognitive Impairment
- Trial name
- NCT06372002
- Testing
- Cognitive Stimulation Therapy (CST)
- Where
- 46 sites in Spain
- Volunteers
- 683 people
- Sponsor
- Instituto de Mayores y Servicios Sociales (IMSERSO)
Gait, Unsteady
Home-based Motor Imagery for Gait Stability in Older Adults. A Cross-over Feasibility Study. (MIGS-F)
Gait stability is reduced as early as from age 40 to 50. Gait stability can be improved in patients with neurological diseases or in healthy elderly persons with exercises.
- Trial name
- MIGS-F (NCT02693756)
- Testing
- Motor imagery
- Where
- Switzerland
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Applied Sciences of Western Switzerland
Under-consumption of Food
Engaging Elderly People Living in Institutions in Eating Situations
Several recent studies have revealed a significant under-consumption of food in hospitals and nursing homes. For instance, at the Dijon University Hospital, 8 out of 10 patients consume less than 80% of the meals served.
- Trial name
- ENGAGE (NCT05239442)
- Testing
- Taste Commission, Evaluation of the taste commissions, Entretien SWOT
- Where
- France
- Volunteers
- 640 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Pre-diabetes
Effects of Milk Powder Intervention on Blood Glucose Control and Fluctuation in Middle-aged and Elderly People With Pre-diabetes
This study aims to conduct a 8-week intervention involving one formula milk powder for middle-aged and elderly individuals with pre-diabetes, assessing its impact on blood glucose control and fluctuations in comparison to…
- Trial name
- NCT06863766
- Testing
- fortified formula milk powder group, regular milk powder group
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Huilian Zhu
Sever Aplastic Anaemia, Elderly (People Aged 65 or More)
Dose-attenuated IST and Hetrombopag in Elderly (≥65 Years) Patients With Severe Aplastic Anemia
This is a prospetive,Single-Center, Single-Arm, Phase IIB Clinical Study.This study aims to evaluate the efficacy and safety of dose-attenuated IST combined with Hetrombopag in elderly patients (≥65 years) with VSAA/SAA.
- Conditions
- Sever Aplastic Anaemia, Elderly (People Aged 65 or More), Immunosuppressive Treatment
- Trial name
- NCT07010237
- Testing
- Dose-attenuated IST and Hetrombopag
- Where
- China
- Volunteers
- 65 people
- Sponsor
- Institute of Hematology & Blood Diseases Hospital, China
Dementia
Montessori-Based Activities for Elderly Persons With Dementia
This study will determine whether montessori-based activities can help older adults with dementia become more responsive to others.
- Trial name
- NCT00079651
- Testing
- Montessori-based dementia programming
- Where
- 5 sites in United States
- Volunteers
- 300 people
- Sponsor
- Menorah Park
Frail Elderly People Hospitalized
Evaluation of the Hospital Pathway for Frail Elderly Patients Hospitalised for Pathologies Leading to Medical Decompensation
People aged over 75 account for 25% of emergency department visits in the Provence Alpes Côte d'Azur region. Depending on the facility, around 50% of these patients are discharged home without being hospitalised.
- Trial name
- FRAGIL (NCT06873256)
- Where
- France
- Volunteers
- 310 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Physical Activity and Wellbeing, Whole Health
Online Mindfulness-based Dance/Movement Therapy on Physical Activity and Whole-Person Health in Older Adults
This randomized controlled trial will examine whether an online, group-based Mindfulness-based Dance/Movement Therapy (M-DMT) intervention can increase physical activity and improve whole-person health among sedentary older…
- Trial name
- MOVE WELL (NCT07852572)
- Testing
- Mindfulness-based Dance/Movement Therapy, Stony Brook Health Education Program (HEP)
- Where
- United States
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Drexel University