Clinical trials: Elderly Population
Abdominal Pain
Study to Evaluate Bioactive Peptides' Effect on Digestive Discomfort Symptoms of the Elderly
This trial will investigate the potential of a bioactive peptide to reduce symptoms of digestive discomfort in a generally healthy elderly population.
- Trial name
- Inflammaging (NCT04450979)
- Testing
- Bioactive hydrolysate
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Nuritas Ltd
Haemophilus Influenzae Type B Infection
Clinical Trial of Lyophilized Haemophilus Influenzae Type b Conjugate Vaccine
This trial is a randomized, partially blinded, positively controlled phase I clinical study. A total of 160 persons aged 18-59 years, 1-5 years, 6-11 months and 2 months (60-89 days) will be recruited into the trial, and the…
- Trial name
- NCT06621654
- Testing
- Lyophilized Haemophilus Influenzae Type b Conjugate Vaccine, Haemophilus Influenzae Type b Conjugate Vaccine
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- CanSino Biologics Inc.
Influenza
Japanese Pediatric H5N1 Vaccine Study
The purpose of this study is to obtain immunogenicity and safety data of an H5N1 pandemic influenza vaccine in a Japanese pediatric population aged 6 months to 17 years
- Trial name
- NCT01911754
- Testing
- H5N1 (Pre-)Pandemic Influenza Vaccine (Whole Virion, Vero Cell-Derived, Inactivated)
- Where
- 2 sites in Japan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Alachua Government Services, Inc.
Dermatitis Atopic
A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis
This is a parallel group, Phase 3, multinational, multicenter, randomized, double blind, placebo-controlled, 3-arm monotherapy study for treatment of participants diagnosed with moderate to severe atopic dermatitis (AD), whose…
- Trial name
- COAST 1 (NCT06130566)
- Testing
- Amlitelimab
- Where
- 148 sites in United States, Argentina and 13 more
- Volunteers
- 601 people
- Sponsor
- Sanofi
Infection in the Elderly
Involvement of the Translation Initiation Factors in Resolution of Inflammation in the Elderly Population
Aging cause specific changes in the immune system. Processes like "immunoessence" and "inflammaging" offend the functioning of the immune cells and expose the elderly patient to infections that can lead to morbidity and death.
- Trial name
- NCT02519361
- Volunteers
- 30 people
- Sponsor
- Meir Medical Center
Depression
Perception of Music and Facial and Vocal Emotions in a Population With and Without Depression
Depressed subjects display a cognitive bias of information processing and emotional self-regulation, which reinforces negative experiences more than positive ones, known as the negativity bias.
- Trial name
- MusInDep (NCT05143983)
- Testing
- Positive valence music, Neutral valence music
- Where
- France
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Cardiovascular Diseases
Melatonin and Risk Of Cardiovascular Events And Malignant Tumors In The Elderly
Cardiovascular diseases and tumors seriously threaten human health. There are many risk factors that affect the occurrence and death of cardiovascular diseases and malignant tumors.
- Trial name
- NCT04631341
- Testing
- Melatonin
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Sarcopenia
Dose Range Finding Study of Bimagrumab in Sarcopenia
The purpose of this study was to determine the efficacy of repeat dosing with multiple dose levels of bimagrumab on patient physical function, skeletal muscle mass and strength in older adults with sarcopenia.
- Trial name
- NCT02333331
- Testing
- bimagrumab
- Where
- 58 sites in United States, Australia and 11 more
- Volunteers
- 217 people
- Sponsor
- Novartis Pharmaceuticals
Atrial Fibrillation (AF), Hypertension
Village-Based Management of Chronic Cardiovascular Disease in Qu Jiang Elderly Population Registry: The BOUQUET Cohort Study
This is a prospective observational cohort study conducted in Qujiang District, Zhejiang Province, China, aiming to evaluate the effectiveness of a comprehensive management program for elderly patients with chronic cardiovascular…
- Conditions
- Atrial Fibrillation (AF), Hypertension, Coronary Heart Disease (CHD), Heart Failure
- Trial name
- NCT07149688
- Testing
- Comprehensive management program (pharmacologic treatment, lifestyle modification, health education, structured follow-up)
- Where
- China
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Beijing Anzhen Hospital
Neisseria Meningitidis Serogroup B
A Phase I Clinical Trial to Assess the Safety and Immunogenicity of DX-104
A randomized, double-blinded, positive-controlled clinical trial will be conducted to observe the safety and immunogenicity of DX-104 in adults 18 to 50 years of age.
- Trial name
- NCT07395739
- Testing
- Bexsero®, Group B Meningococcal OMV Vaccine
- Where
- Australia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Shanghai Yuguan Biotech Co., Ltd.（Delonix Bioworks)
Age-Related Atrophy, Physical Disorder
Efficacy of Neuromuscular Electrical Stimulation in Geriatric Population
The decline in physical function and strength was seen by the nature of aging. The older adults often complain of fatigue. For these reasons, proper rehabilitation approaches should be used to ensure healthy life and to keep the…
- Trial name
- NCT03409575
- Testing
- 5 minutes stimulation, 10 minutes stimulation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Sevim ACARÖZ CANDAN
Elderly, Malnutrition
Effectiveness of Oral Nutritional Supplements (ONS) in a Meals-on-Wheels Population
Researchers will measure weight, height, hand grip strength and quality of life information of Meals on Wheels (MOW) clients who are considered to have nutrition problems.
- Trial name
- NCT00933153
- Testing
- Ensure Plus, Meals on Wheels
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- Texas Christian University
Glaucoma, Glaucoma, Open-Angle
Prevalence of Glaucoma and Normative Data of Ocular Biometry in Elderly Population in Bangkok
The BANMOP eye study is an ophthalmic subproject of the Bangkoknoi Model Project (BANMOP), a community-based initiative integrating electronic health databases with population surveys to sup-port context-specific health promotion…
- Conditions
- Glaucoma, Glaucoma, Open-Angle, Glaucoma, Suspect, Glaucoma, Angle-Closure
- Trial name
- BANMOP (NCT07763288)
- Where
- Thailand
- Volunteers
- 1,470 people, healthy volunteers welcome
- Sponsor
- Siriraj Hospital
Physical Activity and Wellbeing, Whole Health
Online Mindfulness-based Dance/Movement Therapy on Physical Activity and Whole-Person Health in Older Adults
This randomized controlled trial will examine whether an online, group-based Mindfulness-based Dance/Movement Therapy (M-DMT) intervention can increase physical activity and improve whole-person health among sedentary older…
- Trial name
- MOVE WELL (NCT07852572)
- Testing
- Mindfulness-based Dance/Movement Therapy, Stony Brook Health Education Program (HEP)
- Where
- United States
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Drexel University
Healthy
Efficacy and Safety of Ginkgo Biloba in Middle-aged Cognitively Intact Adults
The primary objective of this study was to assess the efficacy and safety of Gingko biloba film-coated tablets in improving cognitive function and neuropsychological functioning of middle-aged cognitively intact adults.
- Trial name
- NCT02181972
- Testing
- Gingko biloba
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
HIV - Human Immunodeficiency Virus
Effect of Extra Virgin Olive Oil Consumption on the Occurrence of Cardiovascular Events in Population Living With HIV
Study Summary: OLEUM VIHTAEGeneral Information Sponsor: Fundación SEIMC - GESIDA Study Title: Effect of Extra Virgin Olive Oil (EVOO) consumption on the occurrence of cardiovascular events in people living with HIV.
- Trial name
- OLEUM VIHTAE (NCT07761819)
- Testing
- The patients must ingest 50 mL of extra virgin olive oil daily
- Where
- Spain
- Volunteers
- 1,324 people
- Sponsor
- Fundacion SEIMC-GESIDA
Fall Risk Assessment, Tele-assessment Reliability
''The Agreement Between Face-to-face and Tele-assessment of Fullerton Advanced Balance (FAB) Scale in Older People''
The purpose of this study is to examine the measurement consistency and reliability of the Fullerton Advanced Balance Scale (FAGBS) between the tele-assessment method and the face-to-face assessment method.
- Conditions
- Fall Risk Assessment, Tele-assessment Reliability, Geriatric Population
- Trial name
- FAB (NCT07178028)
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Femoral Fractures
Supracondylar Distal Femur Fractures and Abaloparatide
Supracondylar femur fractures in the geriatric population present a unique challenge to the orthopaedic surgeon both in terms of fixation, healing, and final extremity axial alignment.
- Trial name
- NCT04626141
- Testing
- Abaloparatide
- Where
- United States
- Sponsor
- Daniel Horwitz
Autism Spectrum Disorder (ASD)
Efficacy and Safety of Bumetanide Oral Liquid Formulation in Children Aged From 2 to Less Than 7 Years Old With Autism Spectrum Disorder.
The purpose of this study was to evaluate the efficacity and the safety of bumetanide/S95008 in the improvement of Autism Spectrum Disorder core symptoms.
- Trial name
- NCT03715153
- Testing
- BUMETANIDE (S95008) for week 0 - 26, Open-Label BUMETANIDE (S95008) for weeks 26 - 52
- Where
- 50 sites in United States, Australia and 10 more
- Volunteers
- 211 people
- Sponsor
- Institut de Recherches Internationales Servier
Seasonal Allergic Rhinitis
Efficacy and Safety of Fixed Dose Combination GSP 301 Nasal Spray (NS) in the Treatment of Seasonal Allergic Rhinitis (SAR)
Study to evaluate the efficacy and safety of GSP 301 NS compared to placebo NS and to individual monotherapies (comparators) as well as the efficacy of these monotherapies (comparators) versus placebo NS over 14 days of study…
- Trial name
- GSP 301-301 (NCT02631551)
- Testing
- GSP 301 NS, Olopatadine HCl NS, Mometasone furoate NS
- Where
- 37 sites in United States
- Volunteers
- 1,180 people
- Sponsor
- Glenmark Specialty S.A.