Clinical trials: Elderly Women
Healthy Volunteers
First-in-human: Single Ascending Dose, Food Effect, Drug-drug Interaction, Multiple Ascending Dose, Proof of Pharmacology
The purpose of this study is to evaluate the safety, tolerability and pharmacokinetics (PK) and pharmacodynamics (PD) of single and multiple ascending oral doses of ASP6282 in healthy male and female subjects.
- Trial name
- NCT02420782
- Testing
- ASP6282, Itraconazole, Pilocarpine
- Where
- 2 sites in Germany, United Kingdom
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Europe B.V.
Healthy
Plyometric Training for Elderly Women
Introduction: the physiological aging process induces several structural changes in the musculoskeletal system. These, in turn, result in functional changes that are reflected in the senescent dependency, determining the…
- Trial name
- NCT02852642
- Testing
- Exercise
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Chronic Kidney Diseases, Hypertension
Inspiratory Muscle Strength Training in Chronic Kidney Disease
More than 80% of individuals with chronic kidney disease have concomitant hypertension and the majority fail to achieve blood pressure control <130/80 mmHg, leading to high risk of cardiovascular diseases and end-stage kidney…
- Conditions
- Chronic Kidney Diseases, Hypertension, Aging, Blood Pressure
- Trial name
- NCT04911491
- Testing
- IMST
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- University of Colorado, Denver
Aging
Fatigability and Physical Performance: Effects of Resistance Training Variables Manipulation
This study evaluate whether resistance training variables modulate the fatigability (power-duration relationship) and physical performance in adults and older adults
- Trial name
- NCT03619070
- Testing
- Resistance training, LL, Resistance training, HL, Resistance training, HVHL
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Triangulo Mineiro
Weight Gain, Women's Health
Preventing Weight Gain in African American Reproductive-Aged Women
The purpose of this research study is to evaluate the effect of a Facebook-delivered weight-gain prevention program versus a Facebook-delivered program with general women's health information.
- Conditions
- Weight Gain, Women's Health, Obesity
- Trial name
- FB--Pilot (NCT02416921)
- Testing
- Weight-gain Prevention, Women's Health
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Urinary Incontinence in Old Age
Keep On Keep Up Bladder Health: Co-creating and Testing a Self-management Technological Solution for Ageing Well
KOKU Bladder aims to develop and test an evidence based digital health program with behavior change techniques to improve bladder health of adults aged 50 and over.
- Trial name
- KOKU Bladder (NCT06583733)
- Testing
- KOKU Bladder, recommendations
- Where
- 4 sites in Lithuania, Spain and 1 more
- Volunteers
- 120 people
- Sponsor
- University of Vic - Central University of Catalonia
Polycystic Ovary Syndrome
Effect of Metformin and Probiotics in Reproductive-aged Patients With Polycystic Ovary Syndrome
The purpose of this clinical trial is to evaluate the safety and effectiveness on the clinical and biological parameters of reproductive-aged PCOS women after a 12-week metformin and/or probiotics administration.
- Trial name
- NCT03336840
- Testing
- Metformin tablets, ProMetS probiotics powder, 1. Metformin tablets; 2. ProMetS probiotics powder
- Where
- China
- Volunteers
- 90 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Hepatic Insufficiency, Renal Insufficiency
A Study of the Pharmacokinetics and Safety of Anaprazole Sodium in Special Populations
The objective of this study is to evaluate the pharmacokinetic profile and safety of anaprazole sodium in adult subjects, particularly including the elderly and those with renal or hepatic impairment.
- Conditions
- Hepatic Insufficiency, Renal Insufficiency, Elderly
- Trial name
- NCT07345689
- Testing
- Anaprazole Sodium enteric-coated tablet
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Xuanzhu Biopharmaceutical Co., Ltd.
HPV Infection
An Exploratory Open-Label Clinical Trial Evaluating the Immunogenicity of the 9-valent 2-dose HPV Vaccination Regimen
The goal of this study is to explore and evaluate whether a 2-dose schedule of Gardasil 9 among young and mid-adult women 16-45 years of age is generally safe and immunogenic, with an antibody response that is not inferior to…
- Trial name
- NCT04206813
- Testing
- Gardasil 9 2 dose regimen, Gardasil 9 3 dose regimen, Gardasil 9 rescue dose
- Where
- United States
- Volunteers
- 352 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Aging
Fatigability of Lower Limb Muscle in Older Adults: Protective Effects of Strength Training Exercise in Old Men and Women
The proposed studies will assess 1) the mechanisms for the age-related increase in fatigability during dynamic exercise (Aims 1 and 2) and 2) the effectiveness of high-velocity resistance training coupled with blood flow…
- Trial name
- NCT03888040
- Testing
- Exercise
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Marquette University
Kidney Disease
A Study of GSK4771261 in Healthy Participants Aged 25 to 55 Years of Age Inclusive
This is a first time in Asia (FTIA) study of GSK4771261 in healthy participants of Chinese, Japanese, and White/European ancestry.
- Trial name
- NCT07600450
- Testing
- GSK4771261
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Healthy
Single Increasing Doses of BIII 890 CL in Healthy Young Male Volunteers and in Healthy Elderly Male and Female Volunteers
Safety, tolerability and pharmacokinetics of BIII 890
- Trial name
- NCT02269215
- Testing
- BIII 890 CL
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Cardiovascular Disease
Cardiovascular Prophylaxis for Postmenopausal Women
The purpose of this study was to examine the effect of 6 months moderate intensity exercise training completed three times per week upon traditional and emerging cardiovascular disease risk factors in postmenopausal women both…
- Trial name
- NCT01219725
- Testing
- Exercise training
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Iron Deficiencies
A Novel Iron-Based Supplement for Athletes Aged 18-25: Phase II
Female endurance athletes are susceptible to iron deficiency and this can impact their exercise performance. This study aims to assess the efficacy of a novel iron supplement in improving iron status, gut microbiome, and exercise…
- Trial name
- NCT06269913
- Testing
- FeSC
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Postmenopausal; Menorrhagia, Physical Inactivity
Effects of Dietary Nitrate Intake on Physical Performance of Middle-aged Women
Through a randomized, crossover, triple-blind, placebo-controlled clinical trial, 15 physically inactive hypertensive women will participate a 8-day trial, each with two intervention protocols: 1) placebo and 2) beetroot; in…
- Conditions
- Postmenopausal; Menorrhagia, Physical Inactivity, Motor Activity
- Trial name
- NCT05820321
- Testing
- Beetroot juice rich in nitrate, Beetroot juice NO3 depleted
- Where
- 2 sites in Brazil
- Volunteers
- 15 people
- Sponsor
- University of Sao Paulo
Multimorbidity, Hypertension
Development and Validation of a Comprehensive Management Service Package for Older Adults With Multimorbidity
This study aims to test a new comprehensive management service package for older adults with two or more chronic conditions (multimorbidity).
- Conditions
- Multimorbidity, Hypertension, Diabetes Mellitus, Coronary Artery Disease
- Trial name
- COMPASS (NCT07151430)
- Testing
- Service Package Group
- Volunteers
- 358 people
- Sponsor
- Xuanwu Hospital, Beijing
Contraception
Comparative Cycle Control Europe
The aim of this study is to evaluate bleeding pattern, cycle control, and safety of this new four-phasic oral contraceptive in comparison to a reference OC.
- Trial name
- NCT00185367
- Testing
- EV/DNG (Qlaira, BAY86-5027, SH T00658K), SH D 593 B (Miranova)
- Where
- 34 sites in Czechia, France and 1 more
- Volunteers
- 798 people, healthy volunteers welcome
- Sponsor
- Bayer
HPV Infection Vaccine Safety SCT1000
A Phase I Safty and Immunogenicity Study of SCT1000 in Healthy Women Aged 18 to 45 Years
A phase 1 random, double blind, positive and placebo control trail was conducted in 120 healthy women in the arm A: 18-26 years old and Arm B: 27-45 years old.
- Trial name
- NCT04921111
- Testing
- SCT1000, Gardasil®9, Gardasil®
- Where
- China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Sinocelltech Ltd.
Overactive Bladder
Efficacy, Safety, and Tolerability of Darifenacin in Patients Aged > 65 Years With Overactive Bladder
The objective of this study is to assess the efficacy, safety and tolerability of 12-weeks treatment with darifenacin in patients aged >Ý 65 years with OAB.
- Trial name
- NCT00171184
- Testing
- Darifenacin
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Novartis
Healthy Male and Female Subjects
Study to Investigate Comparative Pharmacokinetics, Safety, Immunogenicity and Tolerability Between AVT80 and Entyvio
The study has been designed as a randomised, parallel-group, double-blind, 3 arm study to investigate the comparative pharmacokinetics, safety, immunogenicity and tolerability between AVT80 and Entyvio in healthy volunteers.
- Trial name
- NCT06732804
- Testing
- AVT80, Geographical region 1 Entyvio, Geographical region 2 Entyvio
- Where
- 3 sites in Australia, New Zealand
- Volunteers
- 385 people, healthy volunteers welcome
- Sponsor
- Alvotech Swiss AG
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