Clinical trials: Elderly Women
Breast Cancer, Colorectal Cancer
Expectations and Priorities of Elderly Patients for a First Medical Treatment for Cancer
The main objective of study is to describe the priorities of elderly patients (70 years and over) undergoing a first medical treatment for cancer, at initiation of treatment and after 3 months of treatment.
- Conditions
- Breast Cancer, Colorectal Cancer, Kidney Cancer, Lung Cancer
- Trial name
- PRIORITY (NCT02821793)
- Testing
- Consultation, evaluation questionnaire, Geriatric consultation, evaluation questionnaire
- Where
- France
- Volunteers
- 346 people
- Sponsor
- Institut Bergonié
Locally Advanced Cervical Carcinoma
Decision Aid for Chemotherapy in Cisplatin-Intolerant Patients With Locally Advanced Cervical Cancer
The goal of this clinical trial is to investigate the utility and effectiveness of a decision aid in cisplatin-intolerant patients with locally advanced cervical cancer. The main questions it aims to answer are: 1.
- Trial name
- CECIL (NCT05701735)
- Testing
- CECIL Patient Decision Aid
- Where
- 3 sites in Philippines
- Volunteers
- 45 people
- Sponsor
- University of Santo Tomas Hospital, Philippines
Overactive Bladder (OAB)
Study to Evaluate the Efficacy, Safety, and Tolerability of Mirabegron in Older Adult Subjects With Overactive Bladder (OAB)
The purpose of this study was to assess the efficacy, safety and tolerability of mirabegron versus placebo in the treatment of older adult subjects with OAB.
- Trial name
- PILLAR (NCT02216214)
- Testing
- Mirabegron
- Where
- 120 sites in United States, Canada
- Volunteers
- 888 people
- Sponsor
- Astellas Pharma Global Development, Inc.
Tricuspid Regurgitation, Tricuspid Valve Insufficiency
Evaluation of the Impact of Interventional Treatments for Symptomatic, Severe Tricuspid Valve Insufficiency on Renal Integrity and Function, as Well as on Physical Function and Activity in Older Adults.
The hypothesis is that renal function will improve following tricuspid valve intervention. A reduction in renal biomarkers is also expected.
- Conditions
- Tricuspid Regurgitation, Tricuspid Valve Insufficiency, Cardio-Renal Syndrome, Frailty
- Trial name
- TriRenGe (NCT07464106)
- Testing
- Transcatheter edge-to-edge repair (TEER)
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Robert Bosch Medical Center
Healthy Aged Women
A Pilates Exercise Program for Improving Core Strength, Balance and Functional Autonomy in Aged Women
This study is based on assess and contrast isometric and isokinetic core strength, static and dynamic balance, the number of falls, and functional autonomy in three different old women groups after a 18 weeks 1) Pilates-based…
- Trial name
- NCT02506491
- Testing
- Pilates exercise, Muscular exercise, Control Group
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Geriatrics, Chronic Kidney Disease
Evaluation of Endothelial Dysfunction in Geriatric Non-dialysis Chronic Kidney Disease Patients
Brief summary template The goal of this clinical trial is to assess endothelial dysfunction in geriatric non-dialysis CKD patients.
- Conditions
- Geriatrics, Chronic Kidney Disease, Carotis Intima-media Thickness
- Trial name
- EDGeriatrCKD (NCT07430982)
- Testing
- Ultrasonographic and Capillary Measurements
- Where
- Turkey (Türkiye)
- Volunteers
- 101 people
- Sponsor
- Muğla Sıtkı Koçman University
Metastatic Breast Cancer
1303GCC: Trastuzmab & Pertuzumab With Hormonal Therapy or Chemotherapy in Women Aged 60 and Over.
This is a phase II study that combines Trastuzumab with Pertuzumab to see how it works in women age greater than 60 who have been diagnosed with HER2/neu overexpressed locally advanced and/or metastatic breast carcinoma.
- Trial name
- NCT02000596
- Testing
- Trastuzumab plus Pertuzumab, Hormonal Therapy with Anastrozole and Fulvestrant, Chemotherapy with Eribulin
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Maryland, Baltimore
Ovarian Cancer
Retrospective Multicenter Study of Elderly Patients With Ovarian Cancer Treated With Trabectedin and PLD
The median age at which ovarian cancer is diagnosed is 63 years (50-75). This is still a significant adverse factor for survival results.
- Trial name
- NCT05868889
- Testing
- Trabectedin and PLD
- Where
- Spain
- Volunteers
- 43 people
- Sponsor
- Grupo Español de Investigación en Cáncer de Ovario
Tuberculosis
A Study to Investigate the Pharmacokinetics of a Combined Oral Contraceptive When Given Alone and in Combination With GSK3036656 in Female Participants of Non-childbearing Potential Aged 18 to 65 Years of Age
The purpose of this study is to provide data showing if there are any effects of GSK3036656 on a combined oral contraceptive containing Ethinyl Estradiol (EE) and Levonorgestrel (LNG), which will help inform future studies on…
- Trial name
- NCT06354257
- Testing
- Microgynon, GSK3036656
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Ureteral Stent Occlusion, Exposure Laser
Recovery Following Desflurane Versus Sevoflurane for Outpatient Urologic Surgery in Elderly Females
Numerous studies demonstrate that patients have improved immediate recovery characteristics following desflurane anesthesia compared to other volatile agents, including sevoflurane.
- Conditions
- Ureteral Stent Occlusion, Exposure Laser, Ureterostomy; Functional Disturbance, Vaginal Diseases
- Trial name
- NCT01310582
- Testing
- Desflurane, Sevoflurane
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Hahnemann University Hospital
Quality of Life, Posterior Urethral Valve
Study of the Quality of Life in School Aged-children With Posterior Urethral Valves
Posterior urethral valves (PUV) are the most common congenital obstructive lesion of the urethra, affecting from 1 per 3000 to 1 per 8000 live births.
- Conditions
- Quality of Life, Posterior Urethral Valve, Renal Insufficiency, Chronic Renal Disease
- Trial name
- QUALIVUP (NCT06439862)
- Testing
- Children with PUV
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Hospices Civils de Lyon
Infections, Papillomavirus
Study Assessing Risk of Autoimmune Diseases in Females (9 - 25 Years) Exposed to Cervarix® in United Kingdom
This is an observational cohort study to assess the risk of autoimmune disease(s) within 12 months of receiving the first dose of Cervarix® in the exposed cohort and over a comparable period in the unexposed cohorts.
- Trial name
- NCT01953822
- Testing
- Data collection
- Volunteers
- 1,053 people
- Sponsor
- GlaxoSmithKline
Breast Cancer
Doxorubicin Hydrochloride Liposome as First-Line Therapy in Treating Older Women With Metastatic Breast Cancer
RATIONALE: Drugs used in chemotherapy, such as doxorubicin hydrochloride liposome, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00960336
- Testing
- pegylated liposomal doxorubicin hydrochloride
- Where
- France
- Volunteers
- 59 people
- Sponsor
- ARCAGY/ GINECO GROUP
Infections, Papillomavirus
Complementary Testing to Evaluate Immunogenicity of Human Papillomavirus (HPV) Vaccine (580299) in Healthy Female Subjects Aged >/= 26 Years
Infection with human papillomavirus (HPV) has been clearly established as the central cause of cervical cancer. Indeed, certain oncogenic types of HPV can infect the cervix (part of the uterus or womb).
- Trial name
- NCT00456807
- Testing
- Cervarix TM
- Where
- 2 sites in Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Breast Cancer, Colon Cancer
Cancer Prevention and Treatment Among African American Older Adults: Treatment Trial
The Centers for Medicare and Medicaid Services (CMS) has awarded cooperative agreements to 6 sites from across the country (Salt Lake City, UT, Molokai, HI, Houston, TX, Newark, NJ, Detroit, MI, and Baltimore City) to participate…
- Conditions
- Breast Cancer, Colon Cancer, Rectum Cancer, Cervix Cancer
- Trial name
- CPTD (NCT00509444)
- Testing
- Educational materials, educational materials, plus patient navigation
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Conditions
Pilates and Muscle Strength Respiratory
Introduction: Among the systems of the organism, it is believed that the respiratory system is the one which gets older faster due to the greater exposure to environmental pollutants over the years.The Pilates method has emerged…
- Trial name
- NCT02189044
- Testing
- Pilates Exercise
- Where
- Brazil
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Triangulo Mineiro
Skin Care
Dynamic Optical Coherence Tomography(D-OCT) Aging Study: A Preliminary Evaluation of Structural Differences Between Young and Aged Skin, Cellulite and Atrophic Acne Scars in Female Caucasian Subjects With Fitzpatrick Skin Types I-III Utilizing Non-invasive in Vivo D-OCT.
This single-center clinical study is being conducted over the course of 2 weeks to conduct an exploratory pilot study as a preliminary evaluation of D-OCT's ability to measure skin changes from aging.
- Trial name
- NCT03767400
- Testing
- Skin Imaging, Facial Cleanser
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Allergan
Pelvic Floor Disorders
Combination Treatment With BTL-899 and HPM-6000UF Devices
This study will evaluate the clinical efficacy of the BTL-899 and HPM-6000UF devices in combination for non-invasive strengthening of the core muscles and overall improvement in quality of life in elderly patients.
- Trial name
- NCT05537181
- Testing
- BTL-899; HPM-6000UF Treatments
- Where
- 3 sites in United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Menopause, Older Adults
Effects of Hypopressive Abdominal Gymnastics in Urinary Incontinence
The increase in the age of the population is a problem that affects both Spain and the rest of the world. Life expectancy increases, and this will influence the quality of life that older people will have.
- Trial name
- NCT05722821
- Testing
- Hypopressive intervention
- Where
- Spain
- Volunteers
- 112 people
- Sponsor
- University of Jaén
Cervical Cancer, Vulvar Cancer
Long-term Follow-up of Bivalent Human Papillomavirus (HPV) Vaccine Study in Women
This extension study aims to evaluate the long-term protection and immune response of the bivalent HPV vaccine in women aged 18-30 who participated in a previous efficacy study (311-HPV-1003).
- Conditions
- Cervical Cancer, Vulvar Cancer, Vaginal Cancer, CIN - Cervical Intraepithelial Neoplasia
- Trial name
- NCT06776055
- Testing
- HPV-16/18 vaccine
- Where
- 9 sites in China
- Volunteers
- 5,372 people, healthy volunteers welcome
- Sponsor
- Shanghai Zerun Biotechnology Co.,Ltd
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