Clinical trials: Elderly Women
Epidural Catheter, Epidural Analgesia
Epidural Anesthesia for Transurethral Resection of The Prostate
The aim of this study is to assess the effects of different routes of local anesthetic administration in epidural anesthesia applied to patients undergoing transurethral resection of the prostate (TUR-P).
- Conditions
- Epidural Catheter, Epidural Analgesia, Geriatric Cardiology, Urologic Disorders
- Trial name
- NCT06893809
- Testing
- Epidural injection via Tuohy needle, Epidural injection via catheter, Combined epidural injection (needle and catheter)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Hypertension, Vascular Stiffness
Cardiovascular Effects of EVOO in Healthy Reproductive-aged Women
This study aims to compare changes in cardiovascular function and markers of inflammation and metabolic dysfunction in women randomized to treatment with extra virgin olive oil (EVOO) versus those randomized to treatment with a…
- Trial name
- NCT03820336
- Testing
- Extra Virgin Olive Oil, Control Oil
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Vermont Medical Center
Bone and Body Composition, Obesity
Higher Protein Diet and Exercise for Optimal Weight Loss in Elderly Women
The broad aim is to determine efficacy of a weight loss diet higher in protein and lower in carbohydrate combined with low intensity exercise to favorably impact body composition, bone health, physical function, metabolic disease…
- Conditions
- Bone and Body Composition, Obesity, Metabolic Syndrome, Physical Function
- Trial name
- NCT00912210
- Testing
- Whey protein isolate, Maltodextrin powder supplement
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Protein-energy; Imbalance
Assessment of Dietary Protein Needs of Older Women
The purpose of this study is to evaluate dietary protein requirements in elderly women aged 80 years and older using the indicator amino acid oxidation technique.
- Trial name
- NCT01193946
- Testing
- dietary control
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Purdue University
Post Traumatic Stress Symptoms, Preterm Infant
EMDR Therapy in Preterm-Born Infants With Post-Traumatic Stress Symptoms
This study examines a trauma-focused treatment for very young children who were born prematurely and developed post-traumatic stress related symptoms after medical care.
- Trial name
- EMDR-INFANTS (NCT07590778)
- Testing
- Eye Movement Desensitization and Reprocessing (EMDR) storytelling method
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- Tanja Holtackers
Infertility
Recombinant FSH Investigation in the Treatment of Infertility With Assisted Reproductive Technology (ART) (RITA-1)
This trial investigates the effects of FE 999049 compared to placebo.
- Trial name
- RITA-1 (NCT03740737)
- Testing
- Follitropin delta
- Where
- 23 sites in United States
- Volunteers
- 579 people
- Sponsor
- Ferring Pharmaceuticals
Urinary Incontinence, Pelvic Floor Muscle Weakness
The Effects of Pelvic Floor Muscle Training Combined With Otago Exercises in Elderly People With Incontinence
Pelvic floor muscle weakness is one of the most important causes of incontinence. There are many studies supporting that pelvic floor muscle training prevents incontinence and reduces symptom severity, and with A level of…
- Conditions
- Urinary Incontinence, Pelvic Floor Muscle Weakness, Muscle Weakness
- Trial name
- NCT06331039
- Testing
- PFMT, PFMT+Otago
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Manisa Celal Bayar University
Older Adult
High-intensity Interval Training Combined with Muscle-strength Training in Older Women
Women generally live longer than men but often experience a faster muscle mass loss due to inactivity, which can lead to weakness and disability. Despite these risks, women, particularly older women, are less active than men.
- Trial name
- NCT06825130
- Testing
- Exercise
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Healthy Adults
Study of Pharmacokinetics, Safety and Tolerability of Intravenous Methylnaltrexone Bromide
This double-blind, randomized, two-cohort, placebo-controlled, parallel group study characterized the pharmacokinetics, safety, and tolerability of MNTX following single doses and at steady-state during multiple dosing and…
- Trial name
- NCT01366365
- Testing
- methylnaltrexone
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Bausch Health Americas, Inc.
Infections, Papillomavirus
Evaluation of Safety and Immunogenicity of Co-administering HPV Vaccine With Other Vaccines in Healthy Female Subjects
Infection with human papillomavirus (HPV) has been clearly established as the central cause of cervical cancer. Vaccination of pre-teens and adolescents, ideally before sexual debut and thus before exposure to oncogenic HPV, is a…
- Trial name
- NCT00369824
- Testing
- Different formulations of GSK Biologicals' HPV vaccine (580299), Menactra TM, Boostrix TM
- Where
- 50 sites in United States
- Volunteers
- 1,330 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Physical Performance and Fitness in Old Age
Impact of Various Therapeutic Methods on Gait Quality, Physical and Mental Fitness of Postmenopausal Women.
The goal of this clinical trial is to learn which physical activity affects the quality of gait, physical and mental fitness of older women.
- Trial name
- NCT07304622
- Testing
- Coordination Training, Core Training, Mobility Training
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The President Stanisław Wojciechowski State University of Applied Sciences in Kalisz
Polycystic Ovary Syndrome, Polycystic Ovary Syndrome (PCOS)
Observational Study on the Causal Architecture of Polycystic Ovary Syndrome (PCOS)
The goal of this observational study is to learn about the causal architecture of Polycystic Ovary Syndrome (PCOS) in women aged 18 to 45.
- Conditions
- Polycystic Ovary Syndrome, Polycystic Ovary Syndrome (PCOS), PCOS, PCOS (Polycystic Ovary Syndrome)
- Trial name
- NCT07623551
- Testing
- No intervention - observational data collection only
- Volunteers
- 100 people
- Sponsor
- AnnieGuard Corp.
Interventional, Prevention
A Phase II Study of SCT1000 in Healthy Women Aged 18 to 45 Years
A phase II random, double blind, positive and placebo control trail was conducted in 1200 healthy women in the arm A: 18-26 years old and 600 healthy women in the Arm B: 27-45 years old.
- Conditions
- Interventional, Prevention, Randomized
- Trial name
- NCT05060484
- Testing
- SCT1000, Gardasil®9, Gardasil®
- Where
- China
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Sinocelltech Ltd.
Alport Syndrome
A Study to Learn About How Well BAY 3401016 Works in Adults With Alport Syndrome
Alport syndrome (AS) is a rare genetic condition that causes kidney disease, hearing loss, and eye abnormalities that occur due to changes in specific genes (COL4A3, COL4A4, and COL4A5).
- Trial name
- ASSESS (NCT07211685)
- Testing
- BAY 3401016
- Where
- 51 sites in United States, Argentina and 13 more
- Volunteers
- 60 people
- Sponsor
- Bayer
Heart Failure Preserved Ejection Fraction, Pregnancy Complications
Middle-aged Women With Adverse Pregnancy Outcomes and Heart Failure With Preserved Ejection Fraction
Due to the steady increase in the burden of HFpEF, especially in women, it is an important task to search for new markers and early predictors associated with the development of this disease.
- Trial name
- MAPO-HF (NCT06338943)
- Testing
- Echocardiography, Questionnaire
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- National Medical Research Center for Therapy and Preventive Medicine
Sarcopenic Obesity
Metabolic and Molecular Responses Under the Effect of Taurine Supplementation With and Without Multicomponent Training
Sarcopenic obesity is characterized by a progressive decline in muscle mass and an increase in body fat, a condition especially present in the elderly.
- Trial name
- NCT05437952
- Testing
- Taurine and Exercise (Tau+Ex), Taurine (Tau)
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo
Bladder Cancer, Transitional Cell Cancer of the Renal Pelvis and Ureter
S0028, Gemcitabine and Paclitaxel in Treating Patients With Advanced or Recurrent Cancer of the Urinary Tract
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Giving more than one drug may kill more tumor cells.
- Conditions
- Bladder Cancer, Transitional Cell Cancer of the Renal Pelvis and Ureter, Urethral Cancer
- Trial name
- NCT00022633
- Testing
- gemcitabine hydrochloride, paclitaxel
- Where
- 92 sites in United States
- Volunteers
- 65 people
- Sponsor
- SWOG Cancer Research Network
Cardiorespiratory Fitness, Metabolism
Effects of Probiotic and HIIT in Obese Women
The aim of this study is to investigate whether there are the additive effects when implementing both high-intensity interval training (HIIT) and probiotics simultaneously on improving cardiorespiratory endurance and metabolism…
- Conditions
- Cardiorespiratory Fitness, Metabolism, Anthropometry
- Trial name
- NCT06285578
- Testing
- Probiotics supplementation, HIIT training
- Where
- Taiwan
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Taipei
Healthy
Determination of Protein Requirement in Elderly Female Subjects 65-75 Yrs Old
Minimal data are available on protein requirements throughout the lifespan. Currently available recommendations are based on nitrogen balance data. The limitations of the nitrogen balance method have been well described.
- Trial name
- NCT01578733
- Testing
- protein intake.
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Hypertension, Type 2 Diabetes Mellitus
Nanshan Elderly Cohort Study
Objective: The Nanshan Elderly Cohort Study (NECS) aims to investigate the nutritional, as well as other environmental and genetic factors of chronic diseases, such as cardio-metabolic diseases.
- Conditions
- Hypertension, Type 2 Diabetes Mellitus, Cardiovascular Diseases, Stroke
- Trial name
- NECS (NCT03569735)
- Where
- 2 sites in China
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
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