Clinical trials: Elective Cesarean Delivery, open to volunteers
Gastric Emptying, Caesarean Delivery
Comparison of 'Sip Til Send' Regimens Prior to Elective Caesarean Delivery Using Bedside Gastric Ultrasound
'Sip Til send' is a liberal drinking policy that replaces fasting before a caesarean delivery, meaning that women waiting in hospital can freely drink sips of water until they are called from the ward for their delivery.
- Conditions
- Gastric Emptying, Caesarean Delivery, Pregnancy
- Trial name
- NCT07407530
- Testing
- The carbohydrate group represent the interventional group and will utilise the standard carbohydrate-rich drink, The "water group"
- Where
- 2 sites in Ireland
- Volunteers
- 190 people
- Sponsor
- The Rotunda Hospital
Intraoperative Pain
Sensory Stimuli During Cesarean Delivery
During a cesarean delivery (C-section), most patients are awake and receive spinal or epidural anesthesia to block pain from the lower body.
- Trial name
- PIONEER-MC (NCT07340970)
- Testing
- Patient-initiated request for pharmacological intervention during cesarean delivery
- Where
- Canada
- Volunteers
- 1,005 people
- Sponsor
- University of British Columbia
Cesarean Section, Anesthesia, Obstetrical
Dural Puncture Epidural With 27G vs 26G Needles Versus Standard Epidural for Elective Cesarean Delivery
The goal of this clinical trial is to learn whether the dural puncture epidural (DPE) technique shortens the onset time of surgical anesthesia compared with the standard epidural technique in healthy women undergoing elective…
- Conditions
- Cesarean Section, Anesthesia, Obstetrical, Anesthesia, Epidural
- Trial name
- NCT07897045
- Testing
- Standard Epidural Anesthesia, Dural Puncture Epidural With 27G Spinal Needle, Dural Puncture Epidural With 26G Spinal Needle
- Where
- Turkey (Türkiye)
- Volunteers
- 165 people
- Sponsor
- Ankara City Hospital Bilkent
Depression, Postpartum
Effect of Peripartum 40 Hz Audiovisual Stimulation on Postpartum Depression in Women Undergoing Elective Cesarean Section: A Randomized Clinical Trial
Postpartum depression (PPD) is a common mental health condition affecting 10%-30% of new mothers, with serious consequences for both mother and child.
- Trial name
- NCT07807462
- Testing
- 40 Hz Audiovisual Stimulation
- Where
- China
- Volunteers
- 204 people
- Sponsor
- The First People's Hospital of Lianyungang
Hypotension, Spinal Anesthesia
Pupillary Light Reflex to Predict Post-Spinal Hypotension in Elective Cesarean Delivery
This prospective observational cohort study investigates whether pre-anesthetic pupillary light reflex (PLR) parameters can predict the risk of hypotension following spinal anesthesia in women undergoing elective cesarean…
- Conditions
- Hypotension, Spinal Anesthesia, Cesarean Delivery
- Trial name
- NCT07678723
- Testing
- Not applicable- observational study
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Cesarean Section (MeSH: D002585), Postoperative Pain After Cesarean Section
Esketamine Combined With Transcutaneous Electrical Acupoint Stimulation on Postoperative Recovery Quality After Elective Cesarean Section
This study is a prospective randomized controlled trial aimed at evaluating whether the combination of esketamine and transcutaneous electrical acupoint stimulation (TEAS) can improve the quality of postoperative recovery in…
- Conditions
- Cesarean Section (MeSH: D002585), Postoperative Pain After Cesarean Section, Enhanced Recovery After Surgery
- Trial name
- NCT07916051
- Testing
- Esketamine, Active TEAS, Normal Saline
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- Anhui Provincial Hospital
Postoperative Pain, Cesarean Delivery
Comparison of Intrathecal Bupivacaine With and Without Morphine for Post-operative Analgesia in Parturients Undergoing Elective Cesarean Section: A Randomized Controlled Trial
The goal of this clinical trial is to compare intrathecal bupivacaine with or without morphine for postoperative analgesia in patients undergoing elective cesarean section.
- Conditions
- Postoperative Pain, Cesarean Delivery, Analgesia, Obstetrical
- Trial name
- NCT07094802
- Testing
- Intrathecal morphine with bupivacaine, Hyperbaric Bupivicaine
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Music Therapy, Anxiety
Therapy on Perioperative Anxiety and Pain in Patients
This study aims to explore the effects of preoperative education combined with intraoperative music therapy on perioperative anxiety and pain in patients undergoing elective cesarean section.
- Conditions
- Music Therapy, Anxiety, Health Education
- Trial name
- NCT06970431
- Testing
- eoperative Education + Intraoperative Music Therapy Arm, Preoperative Education Alone Arm
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Maternal and Child Health Hospital of Hubei Province
Obstetric Pain
Quality of Postoperative Analgesia and Functional Recovery After Elective Cesarean Delivery
Based on randomization, patients will receive a mixture for spinal anesthesia and will be followed in the following hours for the various outcomes and for functional recovery
- Trial name
- MoFe (NCT06355271)
- Testing
- Fentanyl 1, Fentanyl2, Fentanyl 3
- Where
- Switzerland
- Volunteers
- 63 people
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Anxiety, Pregnancy
Virtual Reality in Elective Caesarean Births Study (VREC)
This study will establish the safety of a known intervention in a novel setting. It will assess how maternal anxiety during the peri-operative period of an elective cesarean section (eCS) is affected by the introduction of a…
- Conditions
- Anxiety, Pregnancy, Pain
- Trial name
- VREC (NCT07130084)
- Testing
- Virtual Reality Educational Film
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Royal United Hospitals Bath NHS Foundation Trust
Respiratory Distress Syndrome
Respiratory Distress and Elective Cesarean Section at Term
Cesarean section is a life-saving surgical operation for women and their newborns. In Egypt, caesarean sections are over-utilized. The rate increased from 27.6 % in 2008 to 51.8 % in 2014, reaching 72.2 % in 2021.
- Trial name
- NCT06874478
- Testing
- Ultrasound
- Where
- Egypt
- Volunteers
- 210 people
- Sponsor
- Assiut University
Dexamethasone, Magnesium Sulphate
Dexamethasone Versus Magnesium Sulphate as an Adjuvant to Bupivacaine in Ultrasound Guided Erector Spinae Plane Block for Postoperative Analgesia in Elective Caesarean Section Under Spinal Anesthesia
This study aims to compare the efficacy of adding dexamethasone and magnesium sulfate as an adjuvant to bupivacaine in bilateral erector spinae block in postoperative pain control in patients undergoing caesarean section under…
- Conditions
- Dexamethasone, Magnesium Sulphate, Adjuvant, Ultrasound
- Trial name
- NCT07139522
- Testing
- Bupivacaine, Dexamethasone, Magnesium sulphate
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Cairo University
Postpartum Hemorrhage
Rectal Misoprostol for Reducing Blood Loss in Elective Cesarean Section
This randomized controlled trial aims to evaluate the efficacy of adding preoperative rectal misoprostol to standard oxytocin for reducing intraoperative and postoperative blood loss in women undergoing elective cesarean section.
- Trial name
- NCT07188207
- Testing
- Oxytocin
- Volunteers
- 282 people
- Sponsor
- Assiut University
Nausea and Vomiting, Postoperative, Cesarean Delivery
Frequency of Occurrence and Risk Factors of Postoperative Nausea and Vomiting During Elective C-section Under Spinal Anesthesia With Preventive Medication
The aim of this study is to learn about the incidence and risk factors of nausea and vomiting during planned caesarean section under spinal anesthesia.
- Conditions
- Nausea and Vomiting, Postoperative, Cesarean Delivery, Spinal Anesthesia, Antiemetic Therapy
- Trial name
- NCT06927830
- Where
- 2 sites in Belgium
- Volunteers
- 400 people
- Sponsor
- University of Liege
Postpartum Hemorrhage, Uterine Atony
Comparison of Effect of Two Different Doses of Intravenous Oxytocin on Patients Undergoing Elective Cesarean Section
Uterine atony and postpartum hemorrhage are important causes of maternal morbidity and mortality following cesarean section. Oxytocin is routinely administered to stimulate uterine contractions and prevent postpartum uterine…
- Conditions
- Postpartum Hemorrhage, Uterine Atony, Elective Cesarean Section
- Trial name
- OXY-CS (NCT07922083)
- Testing
- Oxytocin 5 IU (Low Dose), Oxytocin 10 IU (High Dose)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Shalamar Hospital
Hypotension During Cesarean Delivery, Postoperative Nausea and Vomiting (PONV)
Dexamethasone to Prevent Side Effects of Spinal Anesthesia in Cesarean Delivery
The goal of this clinical trial is to evaluate the effectiveness of intravenous dexamethasone in preventing adverse effects of spinal anesthesia and prolonging postoperative analgesia in parturients undergoing elective cesarean…
- Conditions
- Hypotension During Cesarean Delivery, Postoperative Nausea and Vomiting (PONV), Pain, Postoperative
- Trial name
- NCT07615595
- Testing
- Dexamethasone
- Where
- Vietnam
- Volunteers
- 176 people
- Sponsor
- University Medical Center Ho Chi Minh City (UMC)
Spinal Anesthesia, Pregnancy
Preoperative Shock Indexes and Post-Spinal Hypotension in Cesarean Surgery
This prospective observational study aims to evaluate the predictive performance of preoperative Shock Index (SI) and Modified Shock Index (MSI) for hypotension following spinal anesthesia in elective cesarean surgery.
- Conditions
- Spinal Anesthesia, Pregnancy, Hypotension Postprocedural
- Trial name
- NCT07500519
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Marmara University
Surgical Site Infection
Local Subcutaneous Gentamicin for Prevention of Surgical Site Infection After Elective Cesarean Section
The goal of this clinical trial is to evaluate whether local subcutaneous administration of gentamicin reduces the incidence of surgical site infection (SSI) following elective cesarean section.
- Trial name
- NCT07311395
- Testing
- Gentamicin, Standard antibiotic prophylaxis
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Husband Attendance, Maternal-Neonatal Outcomes
Effect of Husband Attendance on Anesthesia Performance and Maternal-Neonatal Outcomes During Elective Cesarean Section Under Spinal Anesthesia
Family-centered perinatal care has become an integral component of modern obstetric practice, emphasizing emotional support and shared parental experiences during childbirth.
- Trial name
- NCT07641751
- Testing
- Husbands will be allowed to attend the cesarean section procedure, providing emotional support to their partners., Husbands will not be permitted to attend the cesarean section procedure
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Alexandria University
Anesthesia, Pregnancy Related
Upper vs Lower Extremity BP in Spinal Cesarean Using ClearSight
This is a single-center, prospective observational study in patients undergoing cesarean delivery under spinal or combined spinal-epidural anesthesia.
- Conditions
- Anesthesia, Pregnancy Related, Blockades Neuromuscular
- Trial name
- NCT07685730
- Testing
- ClearSight
- Where
- United States
- Volunteers
- 327 people, healthy volunteers welcome
- Sponsor
- Ohio State University