Clinical trials: Elective Surgeries
Elective Major Abdominal Surgery
Postoperative Analgesia of Quadratus Lumborum Block Versus Epidural Block After Major Abdominal Surgeries
Acute postoperative pain is an important issue after major abdominal surgeries for which different analgesic modalities have been tried.
- Trial name
- NCT04541732
- Testing
- Thoracic epidural block, Ultrasound-guided bilateral quadratus lumborum block, Induction of general anaesthesia with propofol
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Mansoura University
Coronary Artery Disease
Comparison of Efficacy of Ivabradine Versus Metoprolol
Ivabradine may be better than Metoprolol for controlling heart rate before Coronary CTA.
- Trial name
- IMAGE (NCT01755663)
- Testing
- Ivabradine and Metoprolol
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Col. Suthee Panichkul
Anesthesia; Functional
Effects of Analgesics in Cesarean Section Elective
Two approved treatments for spinal anesthesia will be compared in women undergoing cesarean section. It is usual to perform cesarean sections using spinal anesthesia with a local anesthetic (bupivacaine) plus some opioid, such as…
- Trial name
- CES (NCT03386630)
- Testing
- Hyperbaric bupivacaine+Sufentanil, Hyperbaric bupivacaine+Morphine
- Where
- Spain
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Fundación Pública Andaluza Progreso y Salud
Postoperative Nausea and Vomiting, Postoperative Pain
Dexamethasone Improves Postoperative Symptoms After Laparoscopic Cholecystectomy
Dexamethasone has been reported to reduce postoperative nausea and vomiting (PONV) after laparoscopic cholecystectomy (LC). However, its effects on other surgical outcomes such as pain and fatigue have been unclear.
- Conditions
- Postoperative Nausea and Vomiting, Postoperative Pain, Postoperative Fatigue
- Trial name
- dxt (NCT01030614)
- Testing
- Dexamethasone
- Where
- Mexico
- Volunteers
- 210 people
- Sponsor
- Instituto Mexicano del Seguro Social
Post Induction Hypotension, Postoperative Morbidity
Preoperative Carotid Doppler Ultrasound Parameters for Prediction of Post-Induction Hypotension in Elective Non-Cardiac Surgery
This prospective observational study aims to evaluate the predictive value of preoperative carotid Doppler ultrasound parameters, including carotid velocity-time integral (carotid VTI) and corrected carotid flow time (ccFT), for…
- Trial name
- NCT07488182
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Necmettin Erbakan University
Depression, Postpartum
Effect of Peripartum 40 Hz Audiovisual Stimulation on Postpartum Depression in Women Undergoing Elective Cesarean Section: A Randomized Clinical Trial
Postpartum depression (PPD) is a common mental health condition affecting 10%-30% of new mothers, with serious consequences for both mother and child.
- Trial name
- NCT07807462
- Testing
- 40 Hz Audiovisual Stimulation
- Where
- China
- Volunteers
- 204 people
- Sponsor
- The First People's Hospital of Lianyungang
Elective Cardiac Surgery
Influence of Corticoids on Renal Function in Cardiac Surgery
Hypothesis: Corticoid treatment in cardiac surgery works renal protective. Study design: Randomized, double blind trial in which one group of patients will receive methylprednisolone and the other group (control) will receive…
- Trial name
- NCT00879931
- Testing
- Methylprednisolone
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- University Hospital, Ghent
Pregabalin, Optic Nerve Sheath Diameter Measurement
Effect of Pregabalin on Optic Nerve Sheath Diameter in Craniotomy Patients.
When patients undergo brain tumor removal surgery (craniotomy), the pressure inside the skull may increase, which can lead to brain swelling and slower recovery.
- Conditions
- Pregabalin, Optic Nerve Sheath Diameter Measurement, Intracranial Pressure Changes
- Trial name
- NCT07630753
- Testing
- Pregabalin
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Benha University
Coronary Artery Disease
Tirofiban in Stenting for Long Coronary Lesion
Periprocedural myonecrosis or infarction are associated with short, intermediate, and long term adverse outcomes. Previous study indicated 12.6% of patients suffered a peri-procedural CK-MB rise by overlapping use of drug-eluting…
- Trial name
- PETITION (NCT01498003)
- Testing
- tirofiban, normal saline solution
- Where
- China
- Volunteers
- 748 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Pregnancy Anemia, Electrocardiography
Effect of Spinal Anesthesia in Elective Cesarean Cases on Frontal QRS Angle in Anemic and Non-Anemic Patients
The QRS-T angle represents a novel marker of myocardial repolarisation. It is defined as the angle difference between the direction of ventricular depolarisation (QRS wave) and the direction of ventricular repolarisation (T…
- Conditions
- Pregnancy Anemia, Electrocardiography, Anesthesia, Spinal
- Trial name
- NCT06434870
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Sanliurfa Mehmet Akif Inan Education and Research Hospital
Cholelithiases
Enhanced Recovery After Cholecystectomy
this study will be conducted involving patients of all genders between the ages of 20 and 60 years who will undergo elective laparoscopic cholecystectomy for uncomplicated symptomatic gallstone disease.
- Trial name
- NCT06339437
- Testing
- ERAS Protocol
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Children Hospital and Institute of Child Health, Lahore
Paroxysmal Atrial Fibrillation, Coronary Artery Disease
Surgical Pulmonary Vein Isolation Efficiency Study
A substantial proportion of patients undergoing elective coronary artery bypass grafting have a history of paroxysmal atrial fibrillation. Paroxysmal atrial fibrillation has adverse short-and long term postoperative effects.
- Trial name
- FIN-PVI (NCT01791218)
- Testing
- CABG, AVR or CABG+AVR and PVI, CABG, AVR or CABG+AVR
- Where
- Finland
- Volunteers
- 2 people
- Sponsor
- Kuopio University Hospital
General Anesthesia
Efficacy and Safety of HSK3486 Compared to Propofol for Adults Undergoing Elective Surgery With General Anesthesia
To demonstrate HSK3486 0.4/0.2 mg/kg (0.4 mg/kg intravenous [IV] slow injection over 30 [±5] seconds for the first dose, an additional 0.2 mg/kg if needed) is non-inferior to propofol 2.0/1.0 mg/kg (2.0 mg/kg IV slow injection…
- Trial name
- NCT05478174
- Testing
- HSK3486, Propofol
- Where
- 23 sites in United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Haisco-USA Pharmaceuticals, Inc.
Cesarean Section
Fluid Volume-hypotension Association in Cesarean Under Neuraxial Anesthesia
Hypotension resulted from neuraxial block is a common problem, of which is a special issue in patients undergoing Cesarean section.
- Trial name
- VOHOCUNA (NCT01013090)
- Testing
- Ringer's Lactate, Six percent hydroxyethyl starch
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Nanjing Medical University
Colorectal Surgery
Impact of Coffee vs Orange Juice on Enhancing Recovery After Laparoscopic Colorectal Surgery
Colorectal surgery, even performed by laparoscopy is followed by a transient episode of GI hypomotility, which results in a postoperative ileus (POI).
- Trial name
- NCT05167890
- Testing
- Coffee, Orange juice
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- National Cancer Institute, Egypt
Nausea/Vomiting
Prospective Controlled Trial On Clear Feeds Versus Low Residue Diet After Surgery In Elective Colorectal Surgery Patients
Prospective randomized controlled trial investigating commencement of low residue diet versus clear feeds on postoperative day one following elective colorectal surgery, with regards to patient tolerability, incidence of nausea…
- Trial name
- NCT01890499
- Testing
- Low Residue diet arm.
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Cedars-Sinai Medical Center
Primary Valvular Heart Disease With Comorbid Coronary Artery Disease, Planned to Undergo Elective On-pump Valve Surgery Due to Primary Mitral and/or Aortic Valvular Heart Disease
Quantitative Flow Ratio (QFR) Guided Coronary Artery Bypass Grafting for Patients Undergoing Primary Valve Surgery With Concomitant Coronary Artery Disease
This is a multicenter, prospective, randomized, blinded, controlled clinical study in patients with planned primary valvular surgery and comorbid coronary artery lesions with diameter stenosis of ≥ 50%, to compare the…
- Trial name
- FAVOR IV-QVAS (NCT03977129)
- Testing
- QFR-guided strategy, CAG-guided strategy
- Where
- 12 sites in China
- Volunteers
- 792 people
- Sponsor
- Ruijin Hospital
Ureteroneocystostomy
The Effect of Intravenous (IV) Patient Controlled Analgesic (PCA) With Ketorolac or Fentanyl Combined With Caudal Block for Postoperative Analgesia in Small Children Undergoing Intravesical Ureteroneocystostomy
The effect of IV PCA with ketorolac or fentanyl combined with caudal block for postoperative analgesia in small children undergoing intravesical ureteroneocystostomy.
- Trial name
- NCT01081535
- Testing
- ketorolac, fentanyl
- Volunteers
- 50 people
- Sponsor
- Yonsei University
Wound Infection
Catheterization During Second Elective Caesarean Delivery
Use versus non use of urinary catheterization during Second Elective caesarean delivery:
- Trial name
- CDSECD (NCT02143089)
- Testing
- Foley's Catheter
- Where
- Egypt
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Hypothermia
An Epidemiology Survey on the Incidence of Perioperative Hypothermia
The purpose of this study is to understand and grasp the incidence rate of hypothermia during perioperative period of elective operations under general anaesthesia in Beijing.
- Trial name
- NCT01913041
- Where
- China
- Volunteers
- 869 people
- Sponsor
- Jie YI
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