Clinical trials: Elective Surgeries
Infection of Cesarian Section Wound Following Delivery
Antibiotic Prophylaxis for Elective Cesarean Section
A randomized controlled study comparing the effect of administration of 1 gm ceftriaxone in elective cesarean section 30-60 min before skin incision versus after cord clamping.
- Trial name
- TOAPFECSACT (NCT02177994)
- Testing
- ceftriaxone 1gm for intravenous infusion
- Where
- Egypt
- Volunteers
- 328 people
- Sponsor
- Ain Shams Maternity Hospital
Anesthesia
Efficacy and Safety of HSK3486 Compared to Propofol in Induction of General Anesthesia in Adults Having Elective Surgery
This is a multicenter, randomized, double-blinded, propofol-controlled, Phase 3 clinical study to evaluate the efficacy and safety of HSK3486 for induction of general anesthesia in adults undergoing elective surgery.
- Trial name
- NCT04711837
- Testing
- HSK3486, Propofol
- Where
- 13 sites in United States
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Haisco-USA Pharmaceuticals, Inc.
Brain Tumor
Influences of Propofol and Sevoflurane Anesthesia in Brain Tumor
In the preoperative waiting area, the patients are randomly assigned and divided into two groups according to the allocation sequence table (corresponding to 1:1 randomization) generated by the computer.
- Trial name
- anesthetics (NCT05141877)
- Testing
- Propofol, Sevoflurane
- Where
- Taiwan
- Volunteers
- 706 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Nausea, Vomiting
Oral Aprepitant and Lower Dose Dexamethasone Versus Aprepitant Alone for Preventing Postoperative Nausea and Vomiting (PONV) After Elective Laparoscopic Surgeries
The combination of aprepitant and lower dose dexamethasone is superior to aprepitant alone with respect to the proportion of patients with a complete response (no vomiting and no use of rescue therapy) during 24 hours after the…
- Trial name
- NCT00835965
- Testing
- Dexamethasone, Aprepitant
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Main Line Health
Anxiety
Assessment of the Aromatherapy to Alleviate Peri Operative Anxiety in Ambulatory Elective Upper Limb Surgery Under Loco-regional Anesthesia
AROMA study is a randomised controlled parallel-group single-site study. Patients randomized in the experimental group benefit from the aromatherapy at their arrival in the operating theatre in the recovery room.
- Trial name
- AROMA (NCT03583801)
- Testing
- Olfactory aromatherapy, without aromatherapy
- Where
- France
- Volunteers
- 289 people
- Sponsor
- University Hospital, Lille
Incisional Hernia, Hernia
Comparison of Mesh Fixation Techniques in Elective Laparoscopic Repair of Incisional Hernia - ReliaTack™ v ProTack™
This study is designed to examine the effects on post operative pain after the use of a fixation device to secure a mesh in the abdomen to repair a hernia of the abdominal wall.
- Conditions
- Incisional Hernia, Hernia, Abdominal Hernia
- Trial name
- TACKoMesh (NCT03434301)
- Testing
- ReliaTack™, Protack™
- Where
- United Kingdom
- Volunteers
- 63 people
- Sponsor
- Manchester University NHS Foundation Trust
Surgery, Brain Tumor
Neurosurgical Transitional Care Programme
Readmissions increasingly serve as a metric of hospital performance, inviting quality improvement initiatives in both medicine and surgery.
- Conditions
- Surgery, Brain Tumor, Brain Tumor, Recurrent, Brain Pathology
- Trial name
- TCP (NCT03593330)
- Testing
- Transitional Care Programme
- Where
- United Kingdom
- Volunteers
- 242 people
- Sponsor
- Barts & The London NHS Trust
Venous Thrombosis
Evaluation of PD 0348292 for Preventing Blood Clots in the Lungs or Deep Leg Veins of Patients After Knee Surgery
To study the safety and effectiveness of several doses of PD 0348292 compared to enoxaparin in preventing blood clots in the lungs or deep leg veins of patients after knee surgery
- Trial name
- NCT00306254
- Testing
- PD 0348292, Enoxaparin
- Where
- 134 sites in United States, Australia and 14 more
- Volunteers
- 1,225 people
- Sponsor
- Pfizer
Anxiety and Fear, Anxiety Depression
Psychological Well-being of Patients Awaiting for Cardiac Surgery During the COVID-19 Pandemic
The effect and impact of postponing cardiac surgery / creating a waiting list as a result of COVID-19 on patients, both psychologically and symptomatically on three groups of patients: 1.
- Conditions
- Anxiety and Fear, Anxiety Depression, Anxiety Postoperative, Psychological Stress
- Trial name
- NCT04406181
- Testing
- HADS, a survey
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Universitair Ziekenhuis Brussel
Elective Abdominal Surgery
Comparison of the Risk of Surgical Site Infections Between Dressings Stopped at Postoperative Day 1 vs Dressings Stopped at Postoperative Day 6+/-1 After Elective Abdominal Surgery
The daily changing of postoperative dressings is a widespread practice, often continuing until the 5th-7th day after surgery. In theory, dressings aim to reduce the risk of superficial surgical site infections (SSIs).
- Trial name
- PAN-STOP (NCT06569862)
- Testing
- Postoperative day 1 dressing, Postoperative day 6+/-1 dressing
- Where
- France
- Volunteers
- 1,288 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Coronary Artery Disease, Chronic Renal Failure
Coronary Rotational Atherectomy Elective vs. Bailout in Severely Calcified Lesions and Chronic Renal Failure
The current role of the rotational atherectomy is for non-dilatable coronary lesions and for severely calcified lesions that may interfere with optimal stent expansion.
- Trial name
- CRATER (NCT05353946)
- Testing
- Percutaneous coronary intervention (PCI)
- Where
- Spain
- Volunteers
- 124 people
- Sponsor
- Guillermo Galeote; MD, PhD
Infertility, Pregnancy, Multiple
eSET Plus Single Embryo Cryotransfer vs Double Embryo Transfer
The purpose of this study is to determine whether a policy of elective single embryo transfer (eSET) plus single embryo cryotransfer is as effective as a double embryo transfer in terms of clinical pregnancy rate
- Trial name
- eSET (NCT01909570)
- Testing
- Elective single embryo transfer, Double embryo transfer
- Where
- Spain
- Volunteers
- 194 people
- Sponsor
- University Hospital Virgen de las Nieves
Elective Colorectal Surgery
Impact of a Bridge Device on the Loop Ileostomy
During the creation of an ileostomy, a bridge device is systematically placed in an aim to reduce wound and peritoneal contamination by stools. Nevertheless no evidence was reported to justify this issue.
- Trial name
- IBIP (NCT02756273)
- Testing
- bridge device, no bridge device
- Where
- 3 sites in France
- Volunteers
- 166 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Hearing Loss; Post-Dural Puncture Headache; Cesarean Delivery
Evaluation of Postoperative Hearing Loss After Spinal Anesthesia for Elective Cesarean Section in Pregnant Women
This prospective observational study will evaluate postoperative hearing changes in women undergoing elective cesarean delivery under spinal anesthesia.
- Trial name
- NCT07697651
- Where
- Turkey (Türkiye)
- Volunteers
- 53 people
- Sponsor
- Duzce University
Spine Surgery
Tranexamic Acid Infusion During Elective Spine Surgery
Tranexamic acid (TXA) is an agent that has been shown to be safe and effective to reduce blood loss in surgical procedures. The purpose of the study is to assess the effect of transexamic on elective decompressive lumbar spine…
- Trial name
- NCT04312880
- Testing
- Tranexamic Acid
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Albany Medical College
Gastric Insufflation, I-gel
Gastric Insufflation Volume Using I-gel Versus Ambu AuraGain in Pediatric Patients Undergoing Elective Orthopedic Operations Under General Anesthesia
Our study aimed to compare the gastric insufflation volume between Ambu AuraGain and i-gel and its relationship with the oropharyngeal sealing pressure and the incidence of postoperative complications in generally anesthetized…
- Conditions
- Gastric Insufflation, I-gel, Ambu AuraGain, Pediatric
- Trial name
- NCT06853756
- Testing
- Ambu Auragain, I-gel
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Breast Cancer, Pain, Postoperative
Erector Spinae Plane Block Versus Paravertebral Block
This study aims to compare the effectiveness of paravertebral block and erector spinae plane block after mastectomy. The primary objective of this randomized controlled trial is to demonstrate equivalent dermatomal spread for…
- Conditions
- Breast Cancer, Pain, Postoperative, Anesthesia, Local
- Trial name
- NCT03471442
- Testing
- Paravertebral block, Erector spinae plane block, General anesthetic
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- University of Alberta
Respiratory Aspiration, Pregnancy
Gastric Sonography in the Fasted Term Pregnant Patient for Elective Cesarean Delivery
Food residue in the stomach of patients scheduled to have surgery is considered a major risk factor for pulmonary aspiration of gastric contents.
- Trial name
- NCT01980121
- Testing
- Ultrasound
- Where
- Canada
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Infectious Complications After Colorectal Surgery
Inflammatory Markers After COloRectal Surgery)
The clinical symptoms of septic complications (SC) (responsible for the majority of morbidity in colorectal surgery) become apparent only 5-7 days after the operation, whereas the efficacy of treatment depends on early diagnosis.
- Trial name
- IMACORS (NCT01510314)
- Testing
- C-reactive protein and procalcitonin dosages
- Where
- 3 sites in France
- Volunteers
- 552 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Intravenous Drug Usage
Median Effective Dose of Dexmedetomidine in Elective Upper Limb Lidocaine Intravenous Regional Anesthesia
Auxiliary drugs augment the effect of local anesthetic in intravenous regional anesthesia (IVRA). The purpose of our study was to estimate the median effective dose (ED50) of Dexmedetomidine in elective upper limb Lidocaine 0.5%…
- Trial name
- dexdix (NCT04304157)
- Testing
- Dexmedetomidine
- Where
- Egypt
- Volunteers
- 81 people
- Sponsor
- South Valley University
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