Clinical trials: Elective Surgeries
Venous Thromboembolism, Arthroplasty, Replacement, Hip
A Study Evaluating Efficacy and Safety of YM150 Compared to Enoxaparin in Subjects Undergoing Hip Replacement Surgery
The purpose of this study is to evaluate the efficacy and safety of various doses of YM150 (the experimental drug) compared to enoxaparin in the prevention of venous thromboembolism in patients that are undergoing elective hip…
- Trial name
- ONYX-3 (NCT00902928)
- Testing
- YM150, enoxaparin
- Where
- 156 sites in United States, Australia and 26 more
- Volunteers
- 1,992 people
- Sponsor
- Astellas Pharma Europe B.V.
Colonoscopy
Study to Investigate the Safety and Efficacy of 3 Dosing Regimens of ABP-700 for Procedural Sedation in Adult Participants Undergoing Colonoscopy
This is a phase II, two-part, multiple-dose, dose-finding, single-blind study in adult participants undergoing elective colonoscopy for screening or diagnostic purposes.
- Trial name
- ABP-700 (NCT02800590)
- Testing
- ABP-700
- Where
- 3 sites in Netherlands
- Volunteers
- 150 people
- Sponsor
- The Medicines Company
Hypotension Drug-Induced
Different Preloads for Prevention of Hypotension in Patients Undergoing Elective CS Under Intrathecal Anesthesia
The aim of this study was to compare between crystalloid versus crystalloid and colloid combination preloads for prevention of hypotension following intrathecal anaesthesia in patients undergoing elective Caesarean section.
- Trial name
- NCT03465943
- Testing
- Ringer, Voluven
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Elective Surgery for Any Digestive Cancer
Benefit of a Flash Dose of Corticosteroids in Digestive Surgical Oncology: a Randomized, Double Blind, Placebo-controlled Trial
Perioperative inflammation is harmful in cancer patients, namely in those undergoing surgery: it increases the risk of recurrence, decreases cancer survival, increases post-operative complications, and prolongs the time of…
- Trial name
- CORTIFRENCH (NCT03875690)
- Testing
- Injection of methylprednisolone, Injection of sodium chloride, Blood samples
- Where
- France
- Volunteers
- 1,200 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Postoperative Pain, Ultrasound Guided Transmuscular Quadratus Lumborum Block
Ultrasound-guided Transmuscular Quadratus Lumborum Block for Elective Laparoscopic Hand-assisted Nephrectomy and Robot Assisted Partiel Nephrectomy
Patients with kidney cancer often undergo hand-assisted laparoscopic nephrectomy or Robot assisted partiel nephrectomy. The investigators performed a one-year retrospective study.
- Trial name
- NCT03571490
- Testing
- Ropivacaine, Saline
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Zealand University Hospital
Knee Arthroplasty, Postoperative Complications
Increased Perioperative Communication Program in Knee Arthroplasty
Total knee replacement (TKA) is a surgical procedure to increase the function of the knee joint. However, in the postoperative period, it takes a long time for patients to gain independence and adapt to daily life, and they need…
- Trial name
- NCT06130813
- Testing
- increased perioperative communication program
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Hacettepe University
Myocardial Infarction
Early Percutaneous Coronary Intervention (PCI) After Fibrinolysis Versus Standard Therapy in ST Segment Elevation Myocardial Infarction (STEMI) Patients
Several recent trials (1,2) suggest that all STEMI patients receiving fibrinolysis in non-PCI centres should be routinely transferred for elective early PCI within 24 hours from hospitalization, with no additive risk of major…
- Trial name
- NCT01014182
- Where
- United Kingdom
- Volunteers
- 3,000 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Hypotension, Anesthesia, General
Internal Jugular Vein Collapsibility Index for Predicting Post-Induction Hypotension
This study aims to investigate whether the Internal Jugular Vein Collapsibility Index (IJV-CI), measured via ultrasonography, can predict hypotension (low blood pressure) that occurs after the induction of general anesthesia.
- Conditions
- Hypotension, Anesthesia, General, Cholecystectomy, Laparoscopic
- Trial name
- IJV-CI (NCT07565025)
- Testing
- IJV-CI Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- University of Gaziantep
Elective Surgery
Neuromuscular Blocking Agents in the Elderly
The number of elderly patients (>80 years) is increasing and a large proportion of these patients will require surgery and anaestheasia within the next decades.
- Trial name
- NCT03857750
- Testing
- Rocuronium
- Where
- Denmark
- Volunteers
- 32 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Umbilical Hernia, Liver Cirrhosis
Conservative Treatment Versus Elective Repair of Umbilical Hernia in Patients With Ascites and Liver Cirrhosis
The purpose of the present study is to investigate whether or not to perform elective surgical repair of umbilical hernias in patients with liver cirrhosis and ascites.
- Conditions
- Umbilical Hernia, Liver Cirrhosis, Ascites
- Trial name
- CRUCIAL (NCT01421550)
- Testing
- Conservative treatment, Surgical repair
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Erasmus Medical Center
Oral Intubation
GlideScope Video Laryngoscope Versus Fiberoptic Intubation
Following informed consent, patients will be randomly assigned to oral fiberoptic intubation or to oral intubation using the GlideScope Video Laryngoscope.
- Trial name
- NCT01091948
- Testing
- Intubation with Fiberoptic laryngoscope, GlideScope® Video Laryngoscope
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- The Cleveland Clinic
Venous Thromboembolism
A Study to Compare the Efficacy and Safety of SRSD107 and Enoxaparin in Adult Subjects Undergoing TKA
This is a Phase 2, multicenter, randomized, open-label, parallel group, blinded endpoint evaluation, active-controlled, dose-finding study.This study is designed to compare the efficacy and safety of 3 dose levels of SRSD107 and…
- Trial name
- NCT07140523
- Testing
- SRSD107, enoxaparin
- Where
- Czechia
- Volunteers
- 450 people
- Sponsor
- Sirius Therapeutics Co., Ltd.
Skull Pin Insertion
The Lowest Effective Dose of Dexmedetomidine in Attenuating the Hemodynamic Responses During Skull Pin Insertion in Patients Undergoing Elective Craniotomy
Skull pins are used to immobilize the head during craniotomy. Fixation of skull pins causes acute hemodynamic changes which may affect cerebral autoregulation and hence cerebral blood flow.
- Trial name
- NCT03738059
- Testing
- Dexmedetomidine Injection [Precedex], normal saline 0.9%
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Assiut University
Prostate Cancer
Androgen Suppression Combined With Elective Nodal and Dose Escalated Radiation Therapy
The purpose of this trial is to compare two similar treatments for patients diagnosed with prostate cancer. The two treatment arms being compared are: (Standard Arm) hormone therapy, which will prevent the production of the male…
- Trial name
- NCT00175396
- Testing
- Androgen suppression, radiotherapy, Androgen suppression, radiotherapy, iodine 125 brachytherapy
- Where
- Canada
- Volunteers
- 400 people
- Sponsor
- University of British Columbia
Quality of Recovery, Pain, Postoperative
Quality of Recovery After Laparoscopic Cholecystectomy Comparing Opioid Free Analgesia Versus Opioid Free Anesthesia
The aim of this study is to compare the quality of recovery from general anesthesia and surgery using the quality of recovery 15 item scale (QoR-15) for participant's receiving opioid-Sparing anesthesia with those receiving…
- Conditions
- Quality of Recovery, Pain, Postoperative, Elective Laparoscopic Cholecystectomy
- Trial name
- NCT06343753
- Testing
- Opioid free analgesia, Opioid based Anesthesia
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Spinal Anesthesia, General Anesthesia
Spinal Versus General Anesthesia for Laparoscopic Cholecystectomy
The purpose of the study is to assess whether spinal anesthesia is or not superior to the standard general anesthesia for fit patients undergoing laparoscopic cholecystectomy.
- Conditions
- Spinal Anesthesia, General Anesthesia, Postoperative Pain
- Trial name
- SALC (NCT00492453)
- Testing
- laparoscopic cholecystectomy
- Where
- Greece
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Elective Surgical Procedures
Fast Track Surgery for Abdominal Surgery in Rwanda
Fast Track Surgery (FTS) was started in colorectal surgery, but was later applied to other surgical fields. Core elements include epidural or regional anaesthesia, perioperative fluid management, minimally invasive surgical…
- Trial name
- NCT03067519
- Testing
- Fast track surgery, Conventional management
- Where
- Rwanda
- Volunteers
- 62 people
- Sponsor
- University of Rwanda
Brain Tumor Adult, Transfusion
Predictive Model to Calculate the Risk of RBC Transfusion in Elective Brain Tumours Resections (TScoreBTR)
To validate a predictive model for the risk of receiving RBCs in this population. This model uses four preoperative values (haemoglobin levels, tumour volume, previous craniotomy in the same spot, and number of craniotomies…
- Conditions
- Brain Tumor Adult, Transfusion, Surgery
- Trial name
- TScoreBTR (NCT05832450)
- Testing
- Red cell concentrate transfusion
- Where
- Spain
- Volunteers
- 1,434 people
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Cancer of Colon, Nutrition Related Cancer
Preoperative Immunonutrition in Patients Undergoing Elective Colorectal Surgery for Neoplasm
Enhanced Recovery After Surgery (ERAS) protocols were developed to standardize perioperative practice in colon surgery to reduce morbidity, improve recovery, and shorten length of stay (LOS).
- Trial name
- NCT05916001
- Testing
- Oral Impact Nestle, Colorectal surgery
- Volunteers
- 216 people
- Sponsor
- University of Roma La Sapienza
Preoperative Care, Surgery--Complications
Vascular Events In Patients Undergoing Same-day Noncardiac Surgery (VALIANCE) Study
The proportion of noncardiac surgeries performed as same-day surgery is increasing worldwide, with more complex surgeries being performed on higher risk patients in the outpatient setting.
- Conditions
- Preoperative Care, Surgery--Complications, Myocardial Infarction
- Trial name
- VALIANCE (NCT04973397)
- Where
- 16 sites in United States, Canada and 2 more
- Volunteers
- 15,000 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
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