Clinical trials: Elective Surgical Patients
the Position of Laryngeal Mask Airway
Comparison Between Blind And Ultrasound Guided Laryngeal Mask Airway Insertion
The Proper position of a laryngeal mask airway (LMA) requires confirmation to ensure the adequacy of laryngeal seal and pulmonary ventilation.
- Trial name
- NCT04090944
- Testing
- the fiberoptic laryngoscope (KARL STORZ 11301BN1, Germany) for confirmation of LMA position
- Where
- Egypt
- Volunteers
- 102 people
- Sponsor
- Beni-Suef University
Thoracic Surgery, Cardiac Surgery
Immunonutrition in Cardiac Surgery
Effect of two preoperative oral immune-enhancing nutritional supplements in patients at high risk of infection after cardiac surgery: a randomized placebo-controlled study.
- Conditions
- Thoracic Surgery, Cardiac Surgery, Cardiopulmonary Bypass
- Trial name
- NCT00247793
- Testing
- Oral Impact (preoperative enteral nutritional supplement)
- Where
- Netherlands
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Anesthesia, Endothelial Dysfunction
Effect of Fluid Challenge on Glycocalyx
Interventional study comparing effect of two regimes of fluid challenge in patients with sepsis and in patients undergoing elective major surgery on glycocalyx by using perfused Boundary Region in sublingual microcirculation.
- Conditions
- Anesthesia, Endothelial Dysfunction, Sepsis, Septic Shock
- Trial name
- NCT03891342
- Testing
- Fluid bolus administration
- Where
- Czechia
- Volunteers
- 120 people
- Sponsor
- University Hospital Hradec Kralove
Frailty Syndrome
Multidisciplinary Prehabilitation to Improve Frailty and Functional Capacity in High-risk Elective Surgical Patients: a Retrospective Pilot Study
Frailty is a multidimensional syndrome in which multiple small physiological deficits accumulate gradually, resulting in a loss of physiological reserve and adaptability, putting a patient that is exposed to stressor at a higher…
- Trial name
- NCT05668221
- Testing
- Prehabilitation
- Where
- Hong Kong
- Volunteers
- 55 people
- Sponsor
- Chinese University of Hong Kong
Airway Management
VieScope in Patients With an Expected Difficult Airway
Patients requiring endotracheal intubation for elective surgery with an expected difficult airway are randomized to be intubated either by a) VieScope or b) videolaryngoscopy.
- Trial name
- NCT05044416
- Testing
- VieScope, Videolaryngoscopy
- Where
- Germany
- Volunteers
- 58 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Major Abdominal Surgery, Duodenohemipancreatectomy
Intraoperative Haemodynamic Optimization Comparing Flow and Pressure Parameters
The purpose of the study is to confirm the hypothesis that flow treatment algorithm based on cardiac index trending by transesophageal Dopplerometry would result in reduced complications and reduced length of hospital stay in…
- Conditions
- Major Abdominal Surgery, Duodenohemipancreatectomy, Rectal Resection, Extensive Bowel Surgery
- Trial name
- Flow-press (NCT02104687)
- Testing
- Flow group, Press group
- Where
- Czechia
- Volunteers
- 140 people
- Sponsor
- University Hospital Ostrava
Hypothermia, Complications
Impact of Expanded Peri Operative Warming
The purpose of this proposed study is to evaluate a normothermia protocol that includes preoperative warming and standard intra operative temperature management in patients undergoing general surgery.
- Trial name
- NCT01649596
- Testing
- Warming Gown, Standard of care warming
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Ascension Health
Elective Surgery, Frail Elderly
Hybrid III Trial of Automated Referral to Comprehensive Geriatric Assessment for Frail Older Surgical Patients
The goal of this observational study is to learn about automated referrals to Perioperative Optimization of Senior Health (POSH).
- Trial name
- NCT07836959
- Testing
- Automated referral, Usual Care Group
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Wisconsin, Madison
Chronic Disease, Old Age; Debility
CONNECARE-Assuta-Case Study 2
The European Union's Horizon 2020 project issued a Call for Action [1] in December 2013 to design, develop, disseminate and evaluate new IT technologies for use in integrative treatment processes, with emphasis on complex adult…
- Trial name
- NCT03327246
- Testing
- Connecare self managment system
- Volunteers
- 220 people
- Sponsor
- Assuta Medical Center
Surgery, Cancer
Post-Discharge Risk-Based Management in Patients Undergoing High-Risk Elective Major Cancer Operations (PRS II)
This is a randomized trial of intensified post-discharge surveillance (Intervention Arm) versus standard post-discharge surveillance (Control Arm).
- Trial name
- NCT05454280
- Testing
- Intensified post-discharge surveillance, Standard post-discharge surveillance
- Where
- United States
- Volunteers
- 526 people
- Sponsor
- Fox Chase Cancer Center
Patients Undergoing Elective Coronary Artery Bypass Graft
Lansoprazole Preventing Gastroduodenal Stress Ulcerations
The primary objective of this study is to determine whether lansoprazole, administered intravenously, can protect patients undergoing cardiac surgery from the development of and/or progression of previously undetected acid/peptic…
- Trial name
- NCT00220909
- Testing
- Lansoprazole
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Temple University
Atrial Fibrillation
Perioperative Anticoagulant Use for Surgery Evaluation Study
The aim of the Perioperative Anticoagulant Use for Surgery Evaluation (PAUSE) Study, is to establish a safe, standardized protocol for the perioperative management of patients with atrial fibrillation (AF) who are receiving a…
- Trial name
- PAUSE (NCT02228798)
- Where
- 21 sites in United States, Belgium and 3 more
- Volunteers
- 3,135 people
- Sponsor
- McMaster University
Laparoscopic Surgery, Hysteroscopic Surgery
Comparison of Sevoflurane, Propofol, and Sevoflurane Plus Propofol for Maintenance of Anaesthesia
Postoperative pain may be affected by general anaesthetics. The effect of propofol and sevoflurane on postoperative pain in chinese female patients has not been demonstrated before.
- Trial name
- NCT01084200
- Testing
- Propofol for maintenance, Sevoflurane, Sevoflurane+Propofol
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Huazhong University of Science and Technology
Oropharyngeal Leak Pressure, Supraglottic Airway
A Randomised Controlled Trial to Compare Two Supraglottic Airway Devices (Ambu AuraGain vs Air Q-3) in Terms of Performance Characteristics.
A supraglottic airway device (SAD) functions as a temporary device to maintain the patency of airway during the administration of anaesthesia.
- Conditions
- Oropharyngeal Leak Pressure, Supraglottic Airway, Elective Surgery, General Anaesthesia
- Trial name
- NCT06914453
- Testing
- Air Q-3 Supraglottic Airway Device, Ambu AuraGain Supraglottic Airway Device
- Where
- Malaysia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Pain, Postoperative, Pain, Acute
A Study of the Effects of Intravenous Magnesium Sulphate on Anaesthesia and Analgesia in Elective General Surgery Patients
The aim of this double-blind randomized study will be to evaluate the effect an intravenous infusion of magnesium has on recovery outcomes after elective laparoscopic cholecystectomy
- Conditions
- Pain, Postoperative, Pain, Acute, Pain, Nociceptive, Analgesia
- Trial name
- NCT05598307
- Testing
- magnesium bolus followed by normal saline infusion, magnesium bolus followed by magnesium infusion, normal saline bolus followed by normal saline infusion
- Where
- Greece
- Volunteers
- 90 people
- Sponsor
- Aretaieion University Hospital
Thrombocytopenia in Chronic Liver Disease Patients Undergoing Elective Invasive Surgery
The Phase III Clinical Study of Herombopag for the Treatment of Thrombocytopenia in Chronic Liver Disease Patients Undergoing Elective Invasive Surgery
This study includes Part A and Part B. Part A is a dose-finding study for subjects with chronic liver disease-related thrombocytopenia scheduled for elective surgery.
- Trial name
- NCT06507436
- Testing
- Herombopag tablets
- Where
- China
- Volunteers
- 127 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Postoperative Pain
Postoperative Pain Therapy With Hydromorphone Using TCI-PCA
Treatment of postoperative pain with hydromorphone (a strong analgesic) using patient-controlled analgesia with target concentrations in blood compared to conventional patient-controlled analgesia after planed cardiac surgery
- Trial name
- TCI-PCA (NCT02035709)
- Testing
- Hydromorphone
- Where
- 2 sites in Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
General Anaesthesia
Comparative Clinical Study of Efficacy and Safety of Remimazolam and Propofol in Patients Undergoing Elective Surgery Under General Anaesthesia
The purpose of this study was to perform comparative evaluation of clinical efficacy and safety of Remimazolam and Propofol for induction and maintenance of general anesthesia in patients undergoing elective surgery under general…
- Trial name
- NCT03669484
- Testing
- Remimazolam, Propofol, Fentanyl
- Where
- 6 sites in Russia
- Volunteers
- 150 people
- Sponsor
- R-Pharm
Colorectal Cancer (Diagnosis)
Effects of a WhatsApp-assisted Prehabilitation for Patient Undergoing Elective Colorectal Cancer Surgery
The goals of this study is to evaluate the feasibility and the effects of a WhatsApp-assisted prehabilitation for colorectal cancer patients undergoing elective surgery.
- Trial name
- NCT07376668
- Testing
- Intervention, Standard care
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- Tseung Kwan O Hospital, Hong Kong
Fatigue
Effects of Oral Iron on Postoperative Fatigue Upon Coronary Artery Bypass Graft Patients
The purpose of this research study is to examine how an oral iron supplement (Feramax®) influences fatigue during early postoperative recovery (at three months) among CABG patients and, the effects on recovery outcomes (e.g.
- Trial name
- NCT01912261
- Testing
- Polysaccharide iron complex
- Where
- Canada
- Volunteers
- 121 people
- Sponsor
- Nova Scotia Health Authority