Clinical trials: Elective Surgical Patients
Prevention, Venous Thromboembolism
Regulation of Coagulation in Orthopedic Surgery to Prevent DVT and PE, a Controlled, Double-blind, Randomized Study of BAY 59-7939 in the Extended Prevention of VTE in Patients Undergoing Elective Total Hip Replacement
The purpose of this study is to assess if 10 mg BAY 59-7939, taken once daily as a tablet, is safe and can help prevent blood clots forming after a hip replacement operation.
- Trial name
- RECORD 2 (NCT00332020)
- Testing
- Rivaroxaban (BAY59-7939), Enoxaparin
- Where
- 126 sites in United States, Australia and 21 more
- Volunteers
- 2,457 people
- Sponsor
- Bayer
Hemophilia
Safety and Efficacy of FVIIa to Prevent Excessive Bleeding in Hemophilia Patients With Inhibitors Undergoing Major Surgery
This is an interventional, prospective, international, multicenter, single-arm, Phase 3, and sequential efficacy and safety study in adolescents and adults with congenital hemophilia A or B with inhibitors to factor VIII (FVIII)…
- Trial name
- SCOPE HIM (NCT05695391)
- Testing
- Coagulation Factor VIIa (Recombinant)
- Where
- 15 sites in United States, Malaysia and 4 more
- Volunteers
- 2 people
- Sponsor
- Laboratoire français de Fractionnement et de Biotechnologies
Airway Management
VieScope in Patients With an Expected Difficult Airway
Patients requiring endotracheal intubation for elective surgery with an expected difficult airway are randomized to be intubated either by a) VieScope or b) videolaryngoscopy.
- Trial name
- NCT05044416
- Testing
- VieScope, Videolaryngoscopy
- Where
- Germany
- Volunteers
- 58 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Anesthesia, Analgesia
The Impact of the Anaesthetic Technique Employed on the Quality of Recovery in Patients Undergoing Hysterectomy Surgery.
The objective of this study is to evaluate the results of different anesthesia methods (general anesthesia with epidural catheter application and spinal anesthesia with epidural catheter application) applied in elective…
- Conditions
- Anesthesia, Analgesia, Acute Pain
- Trial name
- NCT06461832
- Testing
- Group 1, Group 2
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Samsun University
Intubation Complication
Evaluation of Hemodynamic Response to Laryngoscopy and Endotracheal Intubation Using Conventional Laryngoscope Versus C-MAC Video Laryngoscope in Patients Undergoing Elective Coronary Artery Bypass Grafting (CABG) Surgery
This study is being done to compare hemodynamic response upon endotracheal intubation using either conventional laryngoscopy with Macintosh blade versus C-Mac video laryngoscope in patients undergoing elective coronary artery…
- Trial name
- NCT04433884
- Testing
- Endotracheal intubation using a laryngoscope
- Where
- Pakistan
- Volunteers
- 86 people
- Sponsor
- Aga Khan University
Neuromuscular Blockade
Safety and Efficacy of HRS-9190 Compared to Rocuronium for Tracheal Intubation in Adults
The study will enroll adult patients scheduled for elective surgery requiring general anesthesia with tracheal intubation. Participants will be randomly assigned to receive either HRS-9190 for Injection or Rocuronium.
- Trial name
- NCT07252921
- Testing
- HRS-9190
- Where
- 2 sites in China
- Volunteers
- 70 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Pain, Postoperative, Opioid Use
Comparison of Postoperative Nociception Between NOL-guided and Standard Intraoperative Analgesia Based on Fentanyl
Pain is defined as an unpleasant sensory and emotional conscious experience, associated with actual or potential tissue damage. Nociception is the sympathetic response to noxious stimuli during unconsciousness.
- Conditions
- Pain, Postoperative, Opioid Use, Nociceptive Pain, Postoperative Pain
- Trial name
- NOLFentanyl (NCT03858621)
- Testing
- fentanyl NOL guided
- Where
- Chile
- Volunteers
- 100 people
- Sponsor
- Victor Contreras, MSN
Postoperative Complications, COVID-19
Perioperative Complications Linked to COVID-19 History in Elective Cardiac Surgery Patients
A. Primary objective Identifying risk factors for peri-operative complications in patients who have had COVID-19. B. Secondary objectives Identifying peri-operative complications in patients who have had COVID-19.
- Trial name
- NCT05752162
- Where
- 2 sites in Romania
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Carol Davila University of Medicine and Pharmacy
Fatigue
Effects of Oral Iron on Postoperative Fatigue Upon Coronary Artery Bypass Graft Patients
The purpose of this research study is to examine how an oral iron supplement (Feramax®) influences fatigue during early postoperative recovery (at three months) among CABG patients and, the effects on recovery outcomes (e.g.
- Trial name
- NCT01912261
- Testing
- Polysaccharide iron complex
- Where
- Canada
- Volunteers
- 121 people
- Sponsor
- Nova Scotia Health Authority
Cholecystolithiasis, Cholecystitis, Chronic
Elective Endoscopic Gallbladder Treatment: Pilot Study
Laparoscopic cholecystectomy (LC) represents the gold standard for treatment of elective and acute of gallbladder diseases, such as acute cholecystitis (AC).
- Trial name
- SLATAN (NCT05723224)
- Testing
- elective endoscopic gallbladder treatment
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Coronary Artery Disease, Anesthesia
Influence of Oxygen on Perioperative Outcome in Patients Undergoing General Anaesthesia for Elective Non-cardiac Surgery
The purpose of this study is to investigate the impact of supraphysiologic oxygen (hyperoxia) on myocardial function in anaesthetized patients undergoing non-cardiac vascular surgery.
- Trial name
- Promise-O2 (NCT04808401)
- Testing
- Oxygen
- Where
- Switzerland
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Frailty, Frail Elderly
Prehabilitation of Elderly Patients With Frailty Syndrome Before Elective Surgery (PRAEP-GO)
The aim of the study is to evaluate the effect of a shared decision-making conference and three-week prehabilitation program on the outcome "care dependency" one year after surgery.
- Trial name
- NCT04418271
- Testing
- Prehabilitation- new form of care
- Where
- 23 sites in Germany
- Volunteers
- 1,199 people
- Sponsor
- Charite University, Berlin, Germany
General Anesthesia, Elective Surgery
Therapeutic Equivalence (TE) Study of Propofol 2% MCT Fresenius (MCT=Medium-Chain Triglycerides) Compared With Diprivan® in Patients Undergoing Elective Surgery
The purpose of this study is to evaluate the therapeutic equivalence, based on pharmacodynamic parameters of Propofol 2% (20 mg/mL) MCT Fresenius and Diprivan® 20 mg/mL (AstraZeneca), administered by target controlled infusion…
- Trial name
- PropofolTE (NCT01856998)
- Testing
- Propofol, Diprivan
- Where
- France
- Volunteers
- 71 people
- Sponsor
- Fresenius Kabi
Preoperative Patients, Surgical Procedures, Elective
Effect of Virtual Reality Environment Created in Preoperative Area and Hand Massage on Patient Outcomes
The aim of this study is to investigate the effects of video watching with virtual reality glasses and classical hand massage on patient outcomes in patients undergoing elective surgery.
- Conditions
- Preoperative Patients, Surgical Procedures, Elective, Anxiety
- Trial name
- NCT06883916
- Testing
- Virtual reality tour, Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Cukurova University
Elective Surgical Procedure
Perioperative Management & Outcome Following Preoperative Transthoracic Echocardiography in Noncardiac Surgery Patients
In August 2022 the European Society of Cardiology published updated guidelines including recommendations on preoperative transthoracic echocardiography.
- Trial name
- NCT06409234
- Testing
- Transthoracic Echocardiography Recieved
- Where
- Germany
- Volunteers
- 8,250 people
- Sponsor
- European Society of Anaesthesiology
Neuromuscular Blockade, Statin-Associated Myopathy
Evaluation of Neuromuscular Blockade Responses in Statin-Using and Non-Using Patients
This study aims to compare the neuromuscular blockade responses in patients undergoing elective surgery under general anesthesia, with a focus on the use of statins.
- Conditions
- Neuromuscular Blockade, Statin-Associated Myopathy, Neuromuscular Monitoring
- Trial name
- NCT06834776
- Testing
- TOF (Train-of-Four) monitoring for depth of neuromuscular blockade.
- Volunteers
- 104 people
- Sponsor
- Ankara City Hospital Bilkent
Sedation, Preoperative Anxiety Experienced by the Pediatric Patient
Children of Age 2-6years Undergoing Elective Surgery Will be Divided Into Two Groups Randomly. This Study Aims to Evaluate if Intranasal Dexmedetomidine is Better Than Intranasal Ketamine in Producing Sedation and Reducing Parent Separation Anxiety Before Surgery.
This study aims to compare intranasal dexmedetomidine versus intranasal ketamine as a premedication in children undergoing surgery in our population.
- Conditions
- Sedation, Preoperative Anxiety Experienced by the Pediatric Patient, Anxiolytic Effect, Sedation and Analgesia
- Trial name
- DREAM-Kids (NCT07180095)
- Testing
- Intranasal dexmedetomidine, Intranasal ketamine
- Volunteers
- 60 people
- Sponsor
- Liaquat National Hospital & Medical College
Mobile-based Mindfulness Intervention to Reduce Preoperative Anxiety, Pre-operative Anxiety
Effects of Mobile-based Mindfulness Intervention to Reduce Preoperative Anxiety for Patients Undergoing Elective Surgery
This study is a pilot randomized controlled trial (RCT) conducted at Tin Shui Wai Hospital to evaluate the effectiveness of a mobile-based mindfulness intervention in reducing preoperative anxiety among patients scheduled for…
- Conditions
- Mobile-based Mindfulness Intervention to Reduce Preoperative Anxiety, Pre-operative Anxiety, Postoperative Pain, Postoperative Use of Analgesics
- Trial name
- NCT07005973
- Testing
- mobile-based mindfulness intervention
- Where
- Hong Kong
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Hospital Authority, Hong Kong
Postoperative Ileus, Colorectal Surgery
Prucalopride in Postoperative Ileus
Postoperative ileus (POI) refers to the period of gut dysmotility that occurs after abdominal surgery. Patients with POI are unable to eat, suffer ongoing nausea and vomiting, are unable to open their bowels and have a prolonged…
- Conditions
- Postoperative Ileus, Colorectal Surgery, Postoperative Complications
- Trial name
- NCT02947269
- Testing
- Prucalopride
- Where
- New Zealand
- Volunteers
- 150 people
- Sponsor
- University of Auckland, New Zealand
Laparoscopic Surgery, Hysteroscopic Surgery
Comparison of Sevoflurane, Propofol, and Sevoflurane Plus Propofol for Maintenance of Anaesthesia
Postoperative pain may be affected by general anaesthetics. The effect of propofol and sevoflurane on postoperative pain in chinese female patients has not been demonstrated before.
- Trial name
- NCT01084200
- Testing
- Propofol for maintenance, Sevoflurane, Sevoflurane+Propofol
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Huazhong University of Science and Technology