Clinical trials: Elective Surgical Patients
Thromboembolism, Arthroplasty, Replacement, Hip
Dabigatran Etexilate in Extended Venous Thromboembolism (VTE) Prevention After Hip Replacement Surgery
The objective of this study is to determine the comparative efficacy and safety of two oral regimens of dabigatran etexilate, compared to a standard subcutaneous regimen of enoxaparin, in prevention of venous thromboembolism in…
- Trial name
- NCT00168818
- Testing
- dabigatran etexilate, enoxaparin
- Where
- 116 sites in Australia, Austria and 14 more
- Volunteers
- 3,494 people
- Sponsor
- Boehringer Ingelheim
Inguinal Hernia, Quality of Life
Objective and Perceived Quality Study in Patients Undergoing Elective Groin Hernia Surgery
This is a prospective non-comparative observational study of cohorts. Consists on offering surveys to every patient undergoing groin hernia surgery in our Abdominal Wall Surgery Unit, in Hospital of Navarra.
- Conditions
- Inguinal Hernia, Quality of Life, Surgery, Survey
- Trial name
- NCT03860285
- Testing
- Short form 36 quality of life survey
- Where
- Spain
- Volunteers
- 850 people, healthy volunteers welcome
- Sponsor
- Hospital of Navarra
Cataract Surgery, COVID-19
Effect Not Imposing COVID-19 Testing Prior to Elective Cataract Surgery
The world health organization declared corona virus disease (COVID19) a pandemic since march 2020. Since then the future landscape of medical practices and procedures is being heavily shaped by the emergence of this pandemic.
- Trial name
- NCT05217862
- Testing
- PCR for COVID-19 testing
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Central Line Complication
Comparison Between Supraclavicular And Infraclavicular Approach For Right Subclavian Venous Catheterization
A central venous catheter (CVC) is an indwelling device that is peripherally inserted into a larg central vein for a multitude of indications in major elective surgeries and ICU patients and now it's now with notable advance is…
- Trial name
- NCT05140668
- Testing
- Comparison between Supraclavicular And Infraclavicular Approach For Ultrasound-Guided Right Subclavian Venous Catheterization
- Where
- Egypt
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Sohag University
Thromboembolism
Melagatran/Ximelagatran Versus Enoxaparin for the Prevention of Venous Thromboembolic Events
This study is being carried out to study the efficacy and safety of treatment with melagatran injection followed by ximelagatran tablets in preventing blood clots, compared with enoxaparin for a period of 5-6 weeks.
- Trial name
- EXTEND (NCT00206089)
- Testing
- EXANTA
- Where
- 125 sites in Austria, Belgium and 14 more
- Volunteers
- 3,300 people
- Sponsor
- AstraZeneca
Thoracic Aortic Aneurysm, Respiratory Insufficiency
Immunonutrition and Thoracoabdominal Aorta Aneurysm Repair
The purpose of this study is to determine whether immunonutrition and pre operative nutrition can reduce lenght of respirator support, lenght of stay in the ICU and incidence of post operative infections
- Trial name
- NCT00339053
- Testing
- Immunonutrition ( Impact)
- Where
- Netherlands
- Volunteers
- 142 people
- Sponsor
- St. Antonius Hospital
Preoperative, Carbohydrate
Preoperative Two Hours Carbohydrate Load On Pediatric Patient Undergoing Elective Surgery
This work evaluated the systemic effect of different preoperative carbohydrate (CHO) loads in pediatrics undergoing elective surgery.
- Conditions
- Preoperative, Carbohydrate, Pediatric, Elective Surgery
- Trial name
- NCT06833671
- Testing
- Apple juice, Anhydrous glucose, Water
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Diabetes Mellitus Type 2
Carbohydrate Loading in Type 2 Diabetes Mellitus
The goal of this clinical trial is to learn the effects of preoperative carbohydrate loading on perioperative blood glucose levels and insulin resistance in type 2 diabetes mellitus undergo elective surgery.
- Trial name
- NCT06687811
- Testing
- preoperative carbohydrate loading
- Where
- Indonesia
- Volunteers
- 44 people
- Sponsor
- Universitas Indonesia
Cancer of Colon, Cancer of Rectum
Clinical Trial Comparing Standard Care Versus Prehabilitation in Patients Undergoing Cancer Surgery
To determine whether exercise and nutrition prehabilitation improves patient outcomes after cancer surgery
- Conditions
- Cancer of Colon, Cancer of Rectum, Liver Metastases
- Trial name
- SPECS (NCT04880772)
- Testing
- Prehabilitation
- Where
- United Kingdom
- Volunteers
- 42 people
- Sponsor
- East Lancashire Hospitals NHS Trust
To Investigate the Mortality of the Frailty Patients
Hospital Ederly Life Program for Surgical Patients
Frailty is the clinically recognizable medical condition, also called syndrome or phenotype, that is, the result of processes leading to an increased vulnerability for serious deteriorations in health and the diminished ability…
- Trial name
- NCT03792373
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Zhongda Hospital
Coronary Artery Disease, Valvular Heart Disease
Prehabilitation for Patients Undergoing Elective Cardiac Surgery
The objective of this clinical trial is to develop a novel rehabilitation model that, through the PRECICA program, will help to reduce perioperative and postoperative complications in the care process prior to planned cardiac…
- Conditions
- Coronary Artery Disease, Valvular Heart Disease, Chronic Thromboembolic Pulmonary Hypertension, Aortic Diseases
- Trial name
- PRECICA (NCT07704086)
- Testing
- Physical exercise, Educational program and respiration physiotherapy
- Where
- 2 sites in Spain
- Volunteers
- 86 people
- Sponsor
- Hospital Universitario 12 de Octubre
Frailty, Sarcopenia
Frailty and Muscle Strength Tests in Older Adults Undergoing Major Surgery
The goal of this observational study is to learn if simple tests for frailty and muscle strength can help predict which older adults (age 65 and older) are at higher risk for problems after major abdominal surgery.
- Conditions
- Frailty, Sarcopenia, Sarcopenia in Elderly, Muscle Strength
- Trial name
- NCT06988176
- Testing
- Frailty assessment, nutrition assessment, cognition assessment, muscle strength testing
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of North Carolina, Chapel Hill
Neurocognitive Disorders, Neutrophil-Lymphocyte Ratio
NLR and PRL in Neurocognitive Disorders
Preliminary evidence suggest a possible relationship between Neutrophil-Lymphocyte Ratio (NLR) and Platelet-Lymphocyte Ratio (PLR) and perioperative neurocognitive disorders (NCD).
- Conditions
- Neurocognitive Disorders, Neutrophil-Lymphocyte Ratio, Platelet-Lymphocyte Ratio
- Trial name
- NCT04736290
- Testing
- NLR, PLR
- Where
- Greece
- Volunteers
- 288 people
- Sponsor
- University of Thessaly
Elective Cardiac Surgery
Safety and Effectiveness of a Balanced 3rd Generation HES Solution (Tetraspan®) After Cardiac Surgery
The purpose of this randomized controlled trial in patients undergoing cardiac surgery is to show that a 3rd generation HES (Hydroxyethyl Starch) solution - Tetraspan® is as good as in terms of safety and effectiveness as the…
- Trial name
- NCT01418521
- Testing
- Balanced hydroxyethyl starch solution, Ringer- albumin
- Where
- Israel
- Volunteers
- 300 people
- Sponsor
- Rambam Health Care Campus
Colorectal Neoplasms, Diverticulitis
Neomycin and Metronidazole Hydrochloride With or Without Polyethylene Glycol in Reducing Infection in Patients Undergoing Elective Colorectal Surgery
This randomized clinical trial studies how well neomycin and metronidazole hydrochloride with or without polyethylene glycol work in reducing infection in patients undergoing elective colorectal surgery.
- Conditions
- Colorectal Neoplasms, Diverticulitis, Inflammatory Bowel Diseases, Surgical Site Infection
- Trial name
- NCT03042091
- Testing
- Polyethylene Glycol, Neomycin, Metronidazole Hydrochloride
- Where
- United States
- Volunteers
- 224 people
- Sponsor
- Thomas Jefferson University
Postoperative Recovery in Elderly Patients, Quality of Recovery After Elective Surgery
Postoperative Recovery in Elderly Patients Assessed With QoR-15E
Postoperative recovery in elderly patients is an important part of the surgical process and affects how patients feel after surgery.
- Conditions
- Postoperative Recovery in Elderly Patients, Quality of Recovery After Elective Surgery, Perioperative Care Outcomes in Older Adults
- Trial name
- PQoRE (NCT07505758)
- Testing
- QoR-15E questionnaire., Clinical Frailty Scale, Confusional Assessment Method
- Where
- 4 sites in Spain
- Volunteers
- 600 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Acute Respiratory Distress Syndrome
Effect of Low Tidal Volume Ventilation in Improving Oxygenation and Thus Reducing Acute Lung Injury in the Cardiac Surgical Patient
We propose that as low tidal volume ventilation has proven to be beneficial in patients with established ARDS it may have a role in preventing the onset of acute lung injury in the cardiac surgical population.
- Trial name
- NCT00538161
- Testing
- Ventilation strategy
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Beth Israel Deaconess Medical Center
Atrial Fibrillation, Anticoagulant-induced Bleeding
Perioperative Management of Factor Xa Inhibitors
This study aims to analyze the safety and effectiveness of the discontinuation/resumption protocol of factor Xa inhibitors before and after invasive procedures/surgeries in non-valvular atrial fibrillation patients who are at…
- Trial name
- PERIXa (NCT05801068)
- Testing
- Factor Xa Inhibitor
- Where
- South Korea
- Volunteers
- 2,500 people
- Sponsor
- Seoul National University Hospital
Knee Replacement, Total, Knee Replacement Surgery
Hyperbaric Bupivacaine Versus Hyperbaric Prilocaine in Spinal Anaesthesia
Prilocaine numbs you for a shorter time, allowing you to regain movement quicker, which helps you recover faster, start rehab sooner, and feel more satisfied with your treatment overall.
- Trial name
- NCT07329582
- Testing
- prilocaine, Bupivacaine
- Where
- Singapore
- Volunteers
- 50 people
- Sponsor
- National University Hospital, Singapore
Arterial Thromboembolic Events, Atrial Fibrillation
Effectiveness of Bridging Anticoagulation for Surgery (The BRIDGE Study)
Blood thinners, such as warfarin, prevent blood clots from forming, thereby reducing the risk of a stroke or heart attack. When people undergo surgery or certain procedures, they must stop using warfarin to prevent too much…
- Trial name
- NCT00786474
- Testing
- Dalteparin
- Where
- United States
- Volunteers
- 1,884 people, healthy volunteers welcome
- Sponsor
- Duke University